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| 1 | Investigations of the superlubricity of sapphire against ruby under phosphoric acid lubrication显示文摘In this study,we address the superlubricity behavior of sapphire against ruby(or sapphire against itself)under phosphoric acid solution lubrication.An ultra-low friction coefficient of 0.004 was obtained under a very high contact pressure,with a virgin contact pressure up to 2.57 GPa.Related experiments have indicated that the load,sliding speed,and humidity of the test environment can affect superlubricity to some degree,so we tested variations in these conditions.When superlubricity appears in this study a thin film is present,consisting of a hydrogen bond network of phosphoric acid and water molecules adsorbed on the two friction surfaces,which accounts for the ultra-low friction.Most significantly,the wear rate of the sapphire and ruby in the friction process is very slow and the superlubricity state is very stable,providing favorable conditions for future technological applications. | Jinjin LI Chenhui ZHANG Mingming DENG Jianbin LUO | 2014 | Friction2014，2，2： | 13 |
| 2 | Hydrodynamic effect on the superlubricity of phosphoric acid between ceramic and sapphire显示文摘In this work,a super-low friction coefficient of 0.003 was found between a silicon nitride ball and a sapphire plate lubricated by phosphoric acid solution.The wear mainly occurred in the running-in period and disappeared after superlubricity was achieved.The friction coefficient was effectively reduced from 0.3 to 0.003 at a constant speed of 0.076 m/s,accompanied by a 12-nm-thickness film.The lubrication regime was indicated to change from boundary lubrication in the running-in period to elastohydrodynamic lubrication in the superlubricity period,which is also supported by the results of the friction coefficient versus sliding speed.In addition,the experimental results showed good agreement with theoretical calculations based on the elastohydrodynamic lubrication theory,suggesting a significant hydrodynamic effect of phosphoric acid on superlubricity. | Mingming DENG Chenhui ZHANG Jinjin LI Liran MA Jianbin LUO | 2014 | Friction2014，2，2： | 11 |
| 3 | Extraction of Lithium from Salt Lake Brine with Triisobutyl Phosphate in Ionic Liquid and Kerosene显示文摘 | GAO Daolin YU Xiaoping GUO Yafei WANG Shiqiang LIU Mingming DENG Tianlong CHEN Yuwei BELZILE Nelson | 2015 | Chemical Research in Chinese Universities2015，31，4： | 10 |
| 4 | Restoration of electrical microenvironment enhances bone regeneration under diabetic conditions by modulating macrophage polarization显示文摘Macrophage-mediated inflammation compromises bone repair in diabetic patients.Electrical signaling cues are known to regulate macrophage functions.However,the biological effects of electrical microenvironment from charged biomaterials on the immune response for regulating osteogenesis under diabetic conditions remain to be elucidated.Herein the endogeneous electrical microenvironment of native bone tissue was recapitulated by fabricating a ferroelectric BaTiO_(3)/poly(vinylidene fluoridetrifluoroethylene)(BTO/P(VDF-TrFE))nanocomposite membrane.In vitro,the polarized BaTiO_(3)/poly(vinylidene fluoridetrifluoroethylene)(BTO/P(VDF-TrFE))nanocomposite membranes inhibited high glucose-induced M1-type inflammation,by effecting changes in cell morphology,M1 marker expression and pro-inflammatory cytokine secretion in macrophages.This led to enhanced osteogenic differentiation of human bone marrow mesenchymal stem cells(BM-MSCs).In vivo,the biomimetic electrical microenvironment recapitulated by the polarized nanocomposite membranes switched macrophage phenotype from the pro-inflammatory(M1)into the pro-healing(M2)phenotype,which in turn enhanced bone regeneration in rats with type 2 diabetes mellitus.Mechanistic studies revealed that the biomimetic electrical microenvironment attenuated pro-inflammatory M1 macrophage polarization under hyperglycemic conditions by suppressing expression of AKT2 and IRF5 within the PI3K-AKT signaling pathway,thereby inducing favorable osteo-immunomodulatory effects.Our study thus provides fundamental insights into the biological effects of restoring the electrical microenvironment conducive for osteogenesis under DM conditions,and offers an effective strategy to design functionalized biomaterials for bone regeneration therapy in diabetic patients. | Xiaohan Dai Boon Chin Heng Yunyang Bai Fuping You Xiaowen Sun Yiping Li Zhangui Tang Mingming Xu Xuehui Zhang Xuliang Deng | 2021 | Bioactive Materials2021，6，7： | 9 |
| 5 | A new unconventional HLA-A2-restricted epitope from HBV core protein elicits antiviral cytotoxic T lymphocytes显示文摘细胞毒素的 T 房间(CTL ) 在肝炎 B 的控制起一个关键作用病毒(HBV ) 感染和病毒的清理。然而,大多数识别 CTL epitopes 从遗传型 A 和 D 的 HBV 被导出,并且很少在在亚洲更流行的遗传型 B 和 C 的病毒被定义。因为 HBV 核心蛋白质(HBc ) 是最保守、产生免疫性的部件,在这研究,我们使用了盖住 HBc 屏蔽并且识别特定的 CTL epitopes 的一个重叠 9-mer 肽水池。异乎寻常的 HLA-A2-restricted epitope HBc141149 被结晶化分析发现,在结构上描绘了。immunogenicity 和 anti-HBV 活动进一步在 HBV 和 HLA-A2 被决定转基因的老鼠。最后,我们证明在 HBc141149 epitope 的变化与病毒的参数被联系,在 HBV 的疾病前进感染了病人。我们的数据因此提供卓见进这异乎寻常的 epitope 绑定的结构特征给 MHC-I 分子,以及 epitope 特定的 CTL 活动在 HBV 安排 T 房间反应和有免疫力的避免感染的病人。 | Lu Sun Yu Zhang Bao Zhao Mengmeng Deng Jun Liu Xin Li Junwei Hou Mingming Gui Shuijun Zhang Xiaodong Li George F. Gao Songdong Meng | 2014 | Protein & Cell2014，5，4： | 7 |
| 6 | Matrix stiffness modulates tip cell formation through the p-PXN-Rac1-YAP signaling axis显示文摘Endothelial tip cell outgrowth of blood-vessel sprouts marks the initiation of angiogenesis which is critical in physiological and pathophysiological procedures.However,how mechanical characteristics of extracellular matrix(ECM)modulates tip cell formation has been largely neglected.In this study,we found enhanced CD31 expression in the stiffening outer layer of hepatocellular carcinoma than in surrounding soft tissues.Stiffened matrix promoted sprouting from endothelial cell(EC)spheroids and upregulated expressions of tip cell-enriched genes in vitro.Moreover,tip cells showed increased cellular stiffness,more actin cytoskeleton organization and enhanced YAP nuclear transfer than stalk and phalanx ECs.We further uncovered that substrate stiffness regulates FAK and Paxillin phosphorylation in focal adhesion of ECs promoting Rac1 transition from inactive to active state.YAP is subsequently activated and translocated into nucleus,leading to increased tip cell specification.p-Paxillin can also loosen the intercellular connection which also facilitates tip cell specification.Collectively our present study shows that matrix stiffness modulates tip cell formation through p-PXN-Rac1-YAP signaling axis,shedding light on the role of mechanotransduction in tip cell formation.This is of special significance in biomaterial design and treatment of some pathological situations. | Yaru Guo Feng Mei Ying Huang Siqin Ma Yan Wei Xuehui Zhang Mingming Xu Ying He Boon Chin Heng Lili Chen Xuliang Deng | 2022 | Bioactive Materials2022，7，1： | 4 |
| 7 | Controlled synthesis of core-mesoporous shell from biomass sustainable N-doped hollow carbonaceous nanospheres显示文摘 | Chuanlong Han Shiping Wang Jing Wang Mingming Li Jiang Deng Haoran Li YongWang | 2014 | Nano Research2014，7，12： | 3 |
| 8 | Nitrogen-doped flower-like porous carbon materials directed by in situ hydrolysed MgO: Promising support for Ru nanoparticles in catalytic hydrogenations显示文摘为有理想的性质的多孔的碳材料的制造的新奇、简单、方便的技术的发展例如悦耳的毛孔结构和氮功能的存在,从可更新、丰富的 biomasses 被要求。我们此处描述一在里面为任意地采用的做氮的象花的多孔的碳(NFPC ) 的准备指导方法的 situ 从导出简历的 glucosamine 氯化物(GAH ) 塑造了 MgO。试验性的证据证明指导的结构 Mg 完成(哦) 从 MgO 水解作用在 situ 形成的 2 nanosheets 对这个过程关键,与是无关的原来的 MgO 形态学。而且,这个方法为许多导出生物资源的碳先锋是适用的。产生 NFPC 展出了 9 wt.% 的一个高氮内容,并且作为支持被采用抛锚小 Ru nanoparticles (平均尺寸 = 2.7 nm ) 。产生 Ru/NFPC 在甲苯和安息香的酸的异构的加氢是高度活跃的,它表明了氮以增加催化性能做的优点。 | Mingming Li MinghuiTang Jiang Deng Yong Wang | 2016 | Nano Research2016，9，10： | 2 |
| 9 | Effect of layered joints on rockburst in deep tunnels显示文摘The existence of joints in the surrounding rock mass has a considerable efect on tunnel rockbursts.Herein,we studied the efect of layered joints with diferent inclination angles and spacings on rockburst in deep tunnels and investigated the failure area,deformation process of the surrounding rock mass,stress change inside the surrounding rock mass,velocity of the failed rock,and the kinetic energy of the failure.The failure type of the surrounding rock mass can thus be determined.The results showed that the intensity of rockburst increases as rock quality designation(RQD)decreases,while the deformation rate of the surrounding rock mass frst increases and then decreases.The deformation rate exhibits a turning point between RQD=50 and 70,below which the deformation rate of the surrounding rock mass gradually decreases,ultimately ceasing to be a rockburst.Rockburst always occurs perpendicular to the direction of the joint.Whenσ_(x)=σ_(y),as the joint inclination angle changes from 45°to 90°,the intensity of a rockburst frst decreases(from 45°to 60°),and then increases(from 60°to 90°).When combined with the evolution law of stress and strain energy,the rockburst process can be divided into four stages. | Mingming He Jinrui Zhao Bianyuan Deng Zhiqiang Zhang | 2022 | International Journal of Coal Science & Technology2022，9，2： | 2 |
| 10 | Citron C-05 inhibits both the penetration and colonization of Xanthomonas citri subsp.citri to achieve resistance to citrus canker disease显示文摘Citrus canker,caused by Xanthomonas citri subsp.citri(Xcc),is a serious bacterial disease that affects citrus production worldwide.Citron C-05(Citrus medica)is the only germplasm in the Citrus genus that has been identified to exhibit strong resistance to Xcc.However,it has not been determined when,where,and how Xcc is restricted in the tissues of Citron C-05 during the infection process.In the present study,we investigated the spatiotemporal growth dynamics of an eGFP-labeled virulent Xcc(eGFP-Xcc)strain in Citron C-05 along with five susceptible biotypes(i.e.,lemon,pummelo,sour orange,sweet orange,and ponkan mandarin)upon inoculation via the spraying or leaf infiltration of a bacterial suspension.The results from extensive confocal laser scanning microscopy analyses showed that while Xcc grew rapidly in plants of all five susceptible genotypes,Xcc was severely restricted in the epidermal and mesophyll cell layers of the leaves of Citron C-05 in the early stage of infection.Not surprisingly,resistance against Xcc in Citron C-05 was found to be associated with the production of reactive oxygen species and hypersensitive response-like cell death,as well as greater upregulation of several defense-related genes,including a pathogenesis-related gene(PR1)and a glutathione S-transferase gene(GST1),compared with sweet orange as a susceptible control.Taken together,our results not only provide further valuable details of the spatiotemporal dynamics of the host entry,propagation,and spread of Xcc in both resistant and susceptible citrus plants but also suggest that resistance to Xcc in Citron C-05 may be attributed to the activation of multiple defense mechanisms. | Hongyan Fu Mingming Zhao Jing Xu Limei Tan Jian Han Dazhi Li Meijun Wang Shunyuan Xiao Xianfeng Ma Ziniu Deng | 2020 | Horticulture Research2020，7，1： | 2 |
| 11 | Lithium Ion Extraction from the High Ration Mg/Li Salt Lake Brine with Ionic Liquid in Triisobutyl Phosphate and Kerosene显示文摘1 Introduction As the lightest metal with the unique properties of energy production and storage,lithium is regarded as the new century energy metal.Lithium and its compounds were widely used in various industrial fields,especially | GAO Daolin LIU Mingming GUO Yafei YU Xiaoping WANG Shiqiang DENG Tianlong | 2014 | Acta Geologica Sinica(English Edition)2014，88，S1： | 1 |
| 12 | The Phototropism of Jurassic Petrified Wood in North China Plate显示文摘Trees on the side directly exposed to sunlight generally grow faster than on the opposite side,a phenomenon termed plant phototropism.There are in situ vertical trunks of silicified wood in the Xiadelongwan area of Yanqing County,north Beijing,where the first National Geologic Park of Petrified Wood of China has been built since 2002.A few trunks have well-preserved growth rings.One petrified stump from the formation shows a positive phototropism direction of SW23O0.As compared with the modern normal growth stumps in Beijing plain area,which have a positive phototropism direction of SW210 °± 5°,the evidence of wood phototropism supports the conclusion of previous palaeomagnetic studies that the North China Plate has rotated clockwise since the Late Jurassic.The known petrified wood stumps in the Yanshan-Liaoning area are mainly found from the strata of 165-136 Ma,which corresponds to the main stage of the Yanshanian Movement. | JIANG Zikun LIU Benper HUANG Min DENG Shenghui LU Yuanzheng LIU Lu LI Mingming DONG Shuxin WANG Yongdong | 2014 | Acta Geologica Sinica(English Edition)2014，88，5： | 1 |
| 13 | Chrysophanol inhibits the progression of gastric cancer by activating nod-like receptor protein-3显示文摘Aim:Gastric cancer(GC)is one of the most common malignant tumors.Chrysophanol has been reported to possess antitumor effects on a variety of cancers;however,its role in GC remains unclear.This study aimed to investigate the effects of chrysophanol on the proliferation,pyroptosis,migration,and invasion of GC cells.Methods:Human GC cell lines MKN 28 and AGS cells were treated with different concentrations of chrysophanol,then cell proliferation,migration,invasion and pyroptosis were determined by CCK-8,colony-forming assay,wound healing assay,Transwell assay,and flow cytometry.Cell migration and invasion were reassessed in these transfected cells following the transfection of nod-like receptor protein-3(NLRP3)siRNA in MKN 28 and AGS cells.To examine the downstream signaling pathway of the NLRP3 signaling pathway,NLRP3,caspase-1,gasdermin-D,interleukin(IL)-1β,and IL-18 were detected by quantitative real-time-polymerase chain reaction or western blotting.Results:Chrysophanol inhibited the proliferation of GC cells,caused pyroptosis,inhibited cell migration and invasion,and increased the expression of NLRP3 inflammasomes in GC cells.Knockdown of NLRP3 inhibited the effects of chrysophanol on proliferation,pyroptosis,migration,and invasion of GC cells.Chrysophanol plays an anticancer role by enhancing NLRP3.Conclusions:Chrysophanol exerts anti-neoplastic effects in vitro in GC cells by modulating NLRP3,thus highlighting its therapeutic potential in GC. | BINFEN HOU LI ZHAO TIANHAO ZHAO MINGMING YANG WANWAN ZHU XIAODONG CHEN XIQUAN KE ZHENZENG MA LIN GU MENG WANG MIN DENG | 2023 | BIOCELL2023，47，1： | 0 |
| 14 | Transformation Process and Mechanism of Lithium Borates显示文摘Amounts of lithium-containing salt lake brine resources are widely distributed in the four provinces named Qinghai,Tibet,Inner Mongolia and Xinjiang province,especially the salt lakes in Qinghai-Tibet Plateau are abundant | CAO Lina L IU Mingming GAO Daolin GUO Yafei DENG Tianlong | 2014 | Acta Geologica Sinica(English Edition)2014，88，S1： | 0 |
| 15 | Synthesis and Characterization of an Extractant [Bmim]PF_6 for Lithium Ion显示文摘With the rapid increasing demand of metal lithium and its compounds in science and technology,studies on lithium recovery though lithium ion extraction from salt lake brines are blooming bacause more than 60 percent | ZHANG Nan GAO Daolin LIU Mingming DENG Tianlong | 2014 | Acta Geologica Sinica(English Edition)2014，88，S1： | 0 |
| 16 | Insight into the boosted activity of TiO2–CoP composites for hydrogen evolution reaction:Accelerated mass transfer,optimized interfacial water,and promoted intrinsic activity显示文摘The use of abundant elements in the earth as electrocatalytic hydrogen production catalysts is of great significance for hydrogen energy cycling.Herein,we report amorphous TiO_(2)-decorated CoP/NF(TiO_(2)–CoP/NF)as an excellent electrocatalyst for alkaline hydrogen evolution reaction(HER).The welldispersed amorphous TiO_(2)on nanoneedle-like CoP arrays preserves the crystal structure of CoP and changes its electronic structure by interfacial charge transfer.Compared to CoP/NF catalyst,the Ti O_(2)–CoP/NF composite catalyst exhibits high HER activity with an overpotential of 61 mV at 10 mA cm^(-2)and high stability.Importantly,it almost maintains the Volmer step as a rate-determining step(RDS)and the Tafel slope at a wide cathodic potential range showing the fast kinetics under large polarization regions.Theoretical simulations reveal that the combination of TiO_(2)and CoP selectively accelerates the hydrated K+diffusion,regulates the interfacial water orientation to adapt to the subsequent smooth water dissociation,and optimizes*H adsorption/H_(2)desorption.The strengthened coupling of HER multi-scale-processes on transition metal compound composites catalysts is the underlying mechanism for improving HER activity. | Mingming Deng Hongmei Yang Lishan Peng Ling Zhang Lianqiao Tan Guiju He Minhua Shao Li Li Zidong Wei | 2022 | Journal of Energy Chemistry2022，31，11： | 0 |
| 17 | Introduction to the International Symposium on Lipid Science and Health and research progress in lipid science and health显示文摘The International Symposium on Lipid Science and Health(ISLSH),which was organized annually by Oil Crops Research Institute of Chinese Academy of Agricultural Sciences(OCRI-CAAS)since 2016,has gained a strong reputation and attracted hundreds of delegates from around the world for discussion of lipid research trends and advances every year,to promote research and academic exchanges in the fields of lipid science and health.The 5th International Symposium on lipid Science and Health was successfully held in Wuhan,China,from October 23rd to 25th,2020,to celebrate the 60th anniversary of OCRI-CAAS.The two-day symposium gathered wellknown experts specialized in lipid science to share the current state of lipid research with emphasis on aspects covering:(1)lipid profiling and characterization,(2)lipid preparation and modification,(3)lipid improvement and regulation,and(4)lipid nutrition and health.The symposium was conducted by a combination of on-site and network meeting.More than 250 distinguished delegates from academia and industry participated in the on-site multidisciplinary meeting,and thousands of scholars attended the virtual event.This paper is as a record of the symposium proceedings and a brief summary of the advances and trends in 4 aspects of lipid science and health. | Fang Wei Mingming Zheng Qianchun Deng Xia Wan Jiqu Xu Yangmin Gong Hong Chen Fenghong Huang | 2021 | Oil Crop Science2021，6，4： | 0 |
| 18 | Metal-center effect induced efficient charge transfer of metal-organic framework for strengthening Sb(Ⅴ)capture performance显示文摘The adsorbents–adsorbates interaction is critical for resourcelization in heavy metal wastewater treatment.Nevertheless,it is still indistinct to depict the impact of metal center effect on heavy metals removal performance in metal-organic frameworks(MOFs)-based adsorbents.Herein,a series of MOFs with different metal centers of Mg(II),La(III),and Zr(IV)are rationally designed,and the effect of electronic structure on the Sb(V)removal performance is systematically investigated.The obtained La-MGs achieve Sb(V)adsorption capacity of 897.6 mg/g,which is about 1.2 and 4.5 times above average than those of Zr-MGs and Mg-MGs,respectively.On account of more edge adsorption sites achieve,the sites utilization efficiency of La-MGs(92.1%)is much better than Zr-MGs(75.0%)and Mg-MGs(20.4%).Furthermore,density functional theory(DFT)calculations reveal that La-MGs are more active than Mg-MGs and Zr-MGs,owing to the lower adsorption energy,higher charge transfer,and stronger bonding interaction,which will promote the Sb(V)removal performance.The experimental results in practical water indicate that La-MGs effectively capture antimony at low concentration,reaching drinking water standard in samples from Ganjiang River.This study opens an avenue for atomic-level insight into high-efficient absorbents design for water treatment from electronic structuremodification of active centers. | Deng You Hui Shi Mingming Peng Liming Yang Penghui Shao Kai Yin Haozhi Wang Shenglian Luo Xubiao Luo | 2022 | Nano Research2022，15，9： | 0 |
| 19 | Research progress of vegetable oil and derivative in microbial fermentation for high-value-added metabolite production显示文摘Vegetable oil and derivative,as well as waste cooking oil,are important resources for microbial fermentation to produce high-value-added metabolites.Diversity of their compositions not only provides more choices for the fermentation by different microorganisms,but also is a challenge for their systematic utilization.According to the previous literature,4 main functions of vegetable oil and derivative can be summarized,such as carbon source,precursor,inducer and cell protectant during fermentation process.Currently,there is still insufficient knowledge about application of vegetable oil and derivative for high-value-added metabolite production.Therefore,this article firstly presented a comprehensive summary of compositions of vegetable oils and their derivatives,variety of corresponding microbial metabolites,limiting factors and optimization of fermentation process. | Wenchao Chen Meng Wang Qi Zhou Qianchun Deng Mingming Zheng Chen Yang Xia Wan Fenghong Huang | 2019 | Oil Crop Science2019，4，4： | 0 |
| 20 | The contribution of water molecules to the hydrogen evolution reaction显示文摘Traditionally,water molecules act as solvents in most chemical reactions,whereas they act as solvents and reactants in the alkaline electrolyte for the hydrogen evolution reaction(HER).It is well known that there is a current plateau in the linear potential–current dependence for HER in neutral or near-neutral electrolytes,showing that the HER is governed by the mass transport of reactive hydronium species at a given overpotential.The sharp rise in the current signal after the plateau at a slightly higher overpotential indicates that HER is supported by a new reactant,namely the water molecules rather than the limited hydronium species.Herein,in combination with our own research experience in water electrolysis,we review the relevant literature in these years about the HER activity descriptor and mainly focus on the contribution of water molecules to the HER,including their dissociation,configuration,and composition in regulating the pH-dependent HER.Finally,we try to provide new insights into understanding the mechanism of the HER in terms of interfacial water enrichment,orientation,and configuration with the electric field strength of electrode/electrolyte interface and electrode compositions. | Chao Cheng Mingming Deng Li Li Zidong Wei | 2022 | Science China Chemistry2022，65，10： | 0 |
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