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21篇 您的检索式:作者名="Metodiev"
    题名 作者 年代 出处 被引量
1为瘤的劣等的静脉 cava 的切除术和重建显示文摘 AIM: To evaluate the results of an aggressive surgical approach of resection and reconstruction of the inferior vena cava (IVC). METHODS: The approach to caval resection depends on the extent and location of tumor involvement. The supraand infra-hepatic portion of the IVC was dissected and taped. Left and right renal veins were also taped to control the bleeding. In 12 of the cases with partial tangential resection of the IVC, the flow was reduced to less than 40% so that the vein was primarily closed with a running suture. In 3 of the cases, the lumen of the vein was significantly reduced, requiring the use of a polytetrafluoroethylene (PTFE) patch. In 2 of the cases with segmental resection of the IVC, a PTFE prosthesis was used and in 1 case, the IVC was resected without reconstruction due to shunting the blood through the azygos and hemiazygos veins. RESULTS: The mean operation time was 266 min (230-310 min) with an average intraoperative blood loss of 300 mL (200-2000 mL). The patients stayed in intensive care unit for 1.8 d (1-3 d). Mean hospital stay was 9 d (7-15 d). Twelve patients (66.7%) had no complications and 6 patients (33.3%) had the following complications: acute bleeding in 2 patients; bile leak in 2 patients; intra abdominal abscess in 1 patient; pulmonary embolism in 2 patients; and partial thrombosis of the patch in 1 patient. General complications such as pneumonia, pleural effusion and cardiac arrest were observed in the same group of patients. In all but 1 case, the complications were transient and successfully controlled. The mortality rate was 11.1% (n = 2). One patient died due to cardiac arrest and pulmonary embolism in the operation room and the second one died 2 d after surgery due to coagulopathy. With a median follow-up of 24 mo, 5 (27.8%) patients died of tumor recurrence and 11 (61.1%) are still alive, but three of them have a recurrence on computed tomography. CONCLUSION: There are a variety of options for reconstruction after resection of the IVC that offers a higher resectable rate and better prognosis in selected cases.Nikola Nikolov Vladov Vassil Ivanov Mihaylov Nikolai Vassilev Belev Ventzislav Metodiev Mutafchiiski Ivelin Rumenov Takorov Sergei Kirilov Sergeev Evelina Hristova Odisseeva 2012World Journal of Gastrointestinal Surgery2012,4,4:2
2Variable and tissue-specific subunit composition of mitochondrial m-AAA protease complexes linked to hereditary spastic paraplegia显示文摘Koppen M Metodiev MD Casari G 2007Mol Cell Biol2007,27,2:1
3L rpprc is necessary for polyadenylation and coordination of translation of mitochondrial mmas显示文摘Ruzzenente B Metodiev M D Wredenberg A 0,,:1
4Stat1 and CD74 overexpression is co-dependent and linked to increased invasion and lymph node metastasis in triple-negative breast cancer显示文摘Christina Greenwood Gergana Metodieva Khalid Al-Janabi Berthold Lausen Louise Alldridge Lin Leng Richard Bucala Nelson Fernandez Metodi V. Metodiev 2011Journal of Proteomics2011,,10:1
5Adenomatous polyposis coli (APC)protein expression in primary and metastatic serious ovarian carcinoma 显示文摘Karbova E Davidsion B Metodiev K 2002Int J Surg Pathol2002,10,:1
6NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly 显示文摘Metodiev MD Spahr H Loguercio Polosa P 2014PLoS Genet2014,10,10:1
7Differential phosphoproteome profiling by affinity capture and tandem matrix-assisted laser desorption/ionization mass spectrometry显示文摘 TIMANOVA A STONE D E 2004Proteomics2004,4,5:1
8Adenomatous polyposis coli (APC) protein expression in primary and metastatic serous ovarian carcinoma显示文摘Karbova E Davidson Metodiev K 2002Int J Surg Pathol2002,10,:1
9Differential phosphoproteome profiling by affinity capture and tandem matrix-assisted laser desorption/ionization mass spectrometry显示文摘 Timanova A Stone DE 2004Proteomics2004,4,5:1
10Computational fluid dynamics(CFD)simulation of velocity and concentration profiles in the vicinity of immobilized Acidithiobacillus ferrooxidans cells 显示文摘Metodiev B Lilova K Karamanev D 2006Biochemical Engineering Journal2006,,29:1
11Computational fluid dynamics (CFD) simulation of velocity and concentration profiles in the vicinity of immobilized Acidithiobacillus ferrooxidans cells显示文摘B. Metodiev K. Lilova D. Karamanev L. Lilov 2005Biochemical Engineering Journal2005,,:1
12Adenomatous polyposis coli (APC) protein expression in primary and metastatic serous ovarian carcinoma显示文摘Karbova E Davidson Metodiev K 2002Int J Surg Pathol2002,10,3:1
13Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome显示文摘Metodiev M D Lesko N Park C B Cámara Y Shi Y Wibom R Hultenby K Gustafsson C M 0,,04:1
14Adenomatous polyposis coli (APC) protein expression in primary and metastatic serous ovarian carcinoma 显示文摘Karbova E Davidson B Metodiev K 2002Int J Surg Pathol2002,10,3:1
15Methylation of 12S rRNA is necessary for in vivo stability of the small sub- unit of the mammalian mitochondrial ribosome 显示文摘Metodiev M D Lesko N Park C B 2009Cell Metab2009,9,4:1
16Adenomatous polyposis coli (APC) protein expression in primary and metastatic serous ovarian carcinoma显示文摘Karbova E Davidson B Metodiev K 2002lnt J Surg Pathol2002,10,3:1
17Adenomatous polyposis coli (APC) protein expression in primary and metastatic serous ovarian carcinoma 显示文摘Karbova E Davidson B Metodiev K 2002Int J Surg Pathol2002,10,:1
18Adenomatous polyposis coli(APC) protein expression in primary and metastatic serious ovarian tumors 显示文摘Karbova E Dvaidsion B Metodiev K 2002Int J Sugr Patho2002,10,3:1
19Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mamma-lian mitochondrial ribosome 显示文摘Metodiev MD Lesko N Park CB 2009Cell Metab2009,9,4:1
20Methylation of 12s rma is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome显示文摘Metodiev M D Lesko N Park C B 0,,:1
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