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| 1 | Metastatic type 1 gastric carcinoid:A real threat or just a myth?显示文摘AIM:To describe disease characteristics and treatment modalities in a group of rare patients with metastatic gastric carcinoid type 1(GCA1).METHODS:Information on clinical,biochemical,radiological,histopathological findings,the extent of the disease,as well as the use of different therapeutic modalities and the long-term outcome were recorded.Patients’data were assessed at presentation,and thereafter at 6 to 12 monthly intervals both clinically and biochemically,but also endoscopically and histopathologically.Patients were evaluated for the presence of specific symptoms;the presence of autoimmune disorders and the presence of other gastrointestinal malignancies in other family members were also recorded.The evaluation of response to treatment was defined using established WHO criteria.RESULTS:We studied twenty consecutive patients with a mean age of 55.1 years.The mean follow-up period was 83 mo.Twelve patients had regional lymph node metastases and 8 patients had liver metastases.The primary tumor mean diameter was 20.13±10.83mm(mean±SD).The mean Ki-67 index was 6.8%±11.2%.All but one patient underwent endoscopic or surgical excision of the tumor.The disease was stable in all but 3 patients who had progressive liver disease.All patients remained alive during the follow-up period.CONCLUSION:Metastatic GCA1 carries a good overall prognosis,being related to a tumor size of≥1 cm,an elevated Ki-67 index and high serum gastrin levels. | Simona Grozinsky-Glasberg Dimitrios Thomas Jonathan R Strosberg Ulrich-Frank Pape Stephan Felder Apostolos V Tsolakis Krystallenia I Alexandraki Merav Fraenkel Leonard Saiegh Petachia Reissman Gregory Kaltsas David J Gross | 2013 | World Journal of Gastroenterology2013，19，46： | 11 |
| 2 | Role of c-Abl in the DNA damage stress response显示文摘c-Abl has been implicated in many cellular processes including differentiation, division, adhesion, death, and stress response. c-Abl is a latent tyrosine kinase that becomes activated in response to numerous extra- and intra-cellular stimuli. Here we briefly review the current knowledge about c-Abl involvement in the DNA-damage stress response and its implication on cell physiology. | Yosef SHAUL Merav BEN-YEHOYADA | 2005 | Cell Research2005，15，1： | 5 |
| 3 | Women's willingness to be tested for human immunodeficiency virus during pregnancy: A review显示文摘Mother-to-child-transmission of human immunodeficiency virus(HIV) is a primary cause of pediatric infections with HIV. Many of these infections involve women who were not tested early enough in pregnancy, or who didnot receive prevention services. HIV testing of pregnant women is considered to be one of the key strategies for preventing mother-to-child-transmission of HIV, but HIV testing rates among pregnant women in various countries remain suboptimal. Understanding the factors relating to women's willingness to be tested for HIV during pregnancy is critical for developing strategies to increase HIV testing rates among pregnant women. Extensive research points to various factors relating to women's willingness to be tested for HIV during pregnancy, and various recommendations aimed at improving testing rates among pregnant women have been suggested based on the research. In light of the goals set by the United Nations to reduce the rate of infants infected with HIV, it is necessary to summarize what is currently known regarding factors related to women's willingness to be tested for HIV during pregnancy. The purpose of this review is therefore to examine factors related to women's willingness to be tested for HIV during pregnancy, and to summarize recommendations for practice and further research. | Merav Ben-Natan Yelena Hazanov | 2015 | World Journal of Virology2015，4，3： | 4 |
| 4 | Using no-cost mobile phone reminders to improve attendance for HIV test results: a pilot study in rural Swaziland显示文摘Background:Mobile technology has great potential to improve adherence and treatment outcomes in healthcare settings.However,text messaging and phone calls are unaffordable in many resource-limited areas.This study investigates the use of a no-cost alternative mobile phone technology using missed calls(‘buzzing’)to act as a patient reminder.The use of missed calls as a patient reminder was evaluated for feasibility and effectiveness as an appointment reminder in the follow-up of newly-diagnosed human immunodeficiency virus(HIV)positive patients in an HIV testing and counselling department in rural Swaziland.Methods:This pilot study uses a before-and-after operational research study design,with all patients with mobile phones being offered the intervention.The primary outcome was the rate of attendance at the HIV testing and counselling department for collection of results in those with mobile phones before and after the introduction of the intervention.Results:Over two-thirds,71.8%(459/639),of patients had a mobile phone.All patients with a mobile phone consented to being buzzed.There was no difference in attendance for follow-up at the clinic before and after the intervention was implemented(80.1%versus 83.3%,p=0.401),or after adjusting for confounding factors(OR 1.13,p=0.662).Conclusion:This pilot study illustrates that mobile technology may be feasible in rural,resource-poor settings as there are high rates of mobile phone ownership and the intervention had a 100%uptake rate,with positive feedback from staff and patients.In this particular setting,the intervention did not improve attendance rates.However,further research is planned to investigate the impact on adherence to appointments and medications in other settings,such as HIV chronic care follow-up and as part of an enhanced package to improve adherence. | Merav Kliner Abigail Knight Canaan Mamvura John Wright John Walley | 2013 | Infectious Diseases of Poverty2013，2，1： | 2 |
| 5 | Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppresser显示文摘 | Volker HH Jonathan NG Merav S | 2001 | PANS2001，98，4： | 1 |
| 6 | Investigating the factors affecting blood donation among Israelis显示文摘 | Merav B N Lena G | 2011 | Int Emerg Nuts2011，，19： | 1 |
| 7 | Enhancement of Naringenin bioavailability by complexation with hydroxypropoyl-β-cycoldextrin 显示文摘 | Maria S Merav C Alejandro S G | 2011 | Plos One2011，6，4： | 1 |
| 8 | Israelis' perceived motivation for choosing a nursing career 显示文摘 | Merav Ben Natan Fainna Becker | 2010 | Nurse Education Today2010，30，： | 1 |
| 9 | Akt Signaling and cancer: surviving but not moving on显示文摘 | Alex T Merav YL | 2006 | Cancer Res2006，66，9： | 1 |
| 10 | Providing financial incentives to rural-to-urban tuberculosis migrants in Shanghai: an intervention study显示文摘Background:Financial issues are major barriers for rural-to-urban migrants accessing tuberculosis(TB)care in China.This paper discusses the effectiveness of providing financial incentives to migrant TB patients(with a focus on poor migrants in one district of Shanghai using treatment completion and default rates),the effect of financial incentives in terms of reducing the TB patient cost,and the incremental cost-effectiveness ratio of the intervention.Results:Ninety and ninety-three migrant TB patients were registered in the intervention and control districts respectively.TB treatment completion rates significantly improved by 11%(from 78%to 89%)in the intervention district,compared with only a 3%increase(from 73%to 76%)in the control district(P=0.03).Default rates significantly decreased by 11%(from 22%to 11%)in the intervention district,compared with 1%(from 24%to 23%)in the control district(P=0.03).In the intervention district,the financial subsidy(RMB 1,080/US$170)accounted for 13%of the average patient direct cost(RMB 8,416/US$1,332).Each percent increase in treatment completion costs required an additional RMB 6,550(US$1,301)and each percent reduction in defaults costs required an additional RMB 5,240(US$825)in the intervention district.Conclusions:Overall,financial incentives proved to be effective in improving treatment completion and reducing default rates among migrant TB patients in Shanghai.The results suggest that financial incentives can be effectively utilized as a strategy to enhance case management among migrant TB patients in large cities in China,and this strategy may be applicable to similar international settings. | Xiaolin Wei Guanyang Zou Jia Yin John Walley Huaixia Yang Merav Kliner Jian Mei | 2012 | Infectious Diseases of Poverty2012，1，1： | 1 |
| 11 | Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor显示文摘 | Volker H H Jonathan N G Merav S | 2001 | Proe Natl Aead Sei USA2001，98，4： | 1 |
| 12 | Pulmonary endometriosis显示文摘 | Karpel JP Appel D Merav A | | 0，，03： | 1 |
| 13 | Akt Signaling and cancer: surviving but not moving on显示文摘 | Alex T Merav Y L | 2006 | Cancer Res2006，66，9： | 1 |
| 14 | Can life be evaluated?显示文摘 | Raphael Cohen-Almagor and Merav Shmueli | 2000 | Theoretical Medicine and Bioethics2000，，21： | 1 |
| 15 | p73 Overexpression and Nuclear Accumulation in Hepatitis C Virus-Associated Hepatocellular Carcinoma显示文摘 | Romy Zemel Claud Koren Larisa Bachmatove Smadar Avigad Ella Kaganovsky Elimelech Okon Ziv Ben-Ari Franklin Grief Merav Ben-Yehoyada Yosef Shaul Ran Tur-Kaspa | 2002 | Digestive Diseases and Sciences2002，，4： | 1 |
| 16 | Accuracyof gray-scale coding in lung sound mapping显示文摘 | Atul C Mehta Merav Gat Shlomit Mann | 2010 | Comput-erized Medical Imagine and Graphics journal homepage2010，34，5： | 1 |
| 17 | Soil-borne strain IC14 of Serratia plymuthica with multiple mechanisms of antifungal activity provides biocontrol of Botrytis cinerea and Sclerotinia sclerotiorum diseases 显示文摘 | Merav K Marianna O Ilan C h | 2003 | Soil B iol Bioehem2003，35，： | 1 |
| 18 | Akt signaling and cancer:surviving but not moving on显示文摘 | Alex T Merav YL | 2006 | Cancer Res2006，66，4： | 1 |
| 19 | mTOR inhibition by rapamycin prevents β-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes显示文摘 | Merav F Mali KG Yafa A | 2008 | Diabetes2008，57，4： | 1 |
| 20 | Cloning and expression of the genes involved in the production of and immunity against the bacteriocin lacticin RM显示文摘 | Merav Yarmus Anait Mett Roni Shapira | 2000 | BBA - Gene Structure and Expression2000，，3： | 1 |
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