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| 1 | Recurrence of lymphangioleiomyomatosis: Nine years after a bilateral lung transplantation显示文摘Lymphangioleiomyomatosis(LAM) is a rare, slowly progressive lethal lung disease primary afflicting young women. LAM is characterized by proliferation of abnormal smooth muscle cells that target the lungs, causing cystic destruction and eventual respiratory failure leading to death. Recent ten year mortality due to end stage LAM has been reported to be approximately 10%-20%, but may vary. The decline in lung function in LAM is gradual, occurring at a rate of about 3% to 15% per year but can vary from patient to patient. But recently therapy with mammalian target of rapamycin(m TOR) inhibitors such as sirolimus has shown promising results in the stabilization of lung function and reduction of chylous effusions in LAM. Lung transplantation is a viable option for patients who continue to have decline in lung function despite m TOR therapy. Unique issues that may occur post-transplant in a recipient with LAM include development of chylous effusion and a risk of recurrence. We describe a case of LAM recurrence in a bilateral lung transplant recipient who developed histological findings of LAM nine years after transplantation. | Khawaja S Zaki Zahra Aryan Atul C Mehta Olufemi Akindipe Marie Budev | 2016 | World Journal of Transplantation2016，6，1： | 3 |
| 2 | Accuracyof gray-scale coding in lung sound mapping显示文摘 | Atul C Mehta Merav Gat Shlomit Mann | 2010 | Comput-erized Medical Imagine and Graphics journal homepage2010，34，5： | 1 |
| 3 | Cardiovascular magnetic resonance measurement of myocardial extracellular volume in health and disease显示文摘 | Daniel M Sado Andrew S Flett Sanjay M Banypersad Steven K White Viviana Maestrini Giovanni Quarta Robin H Lachmann Elaine Murphy Atul Mehta Derralynn A Hughes William J McKenna Andrew M Taylor Derek J Hausenloy Philip N Hawkins Perry M Elliott James C Moo | 2012 | Heart2012，，19： | 1 |
| 4 | Spontaneous pneumothorax in a single lung transplant recipient-a blessing in disguise: A case report显示文摘BACKGROUND End-stage chronic obstructive pulmonary disease(COPD)is one of the common lung diseases referred for lung transplantation.According to the international society of heart and lung transplantation,30%of all lung transplantations are carried out for COPD alone.When compared to bilateral lung transplant,singlelung transplant(SLT)has similar short-term and medium-term results for COPD.For patients with severe upper lobe predominant emphysema,lung volume reduction surgery is an excellent alternative which results in improvement in functional status and long-term mortality.In 2018,endobronchial valves were approved by the Food and Drug Administration for severe upper lobe predominant emphysema as they demonstrated improvement in lung function,exercise capacity,and quality of life.However,the role of endobronchial valves in native lung emphysema in SLT patients has not been studied.CASE SUMMARY We describe an unusual case of severe emphysema who underwent a successful SLT 15 years ago and had gradual worsening of lung function suggestive of chronic lung allograft dysfunction.However,her lung function improved significantly after a spontaneous pneumothorax of the native lung resulting in auto-deflation of large bullae.CONCLUSION This case highlights the clinical significance of native lung hyperinflation in single lung transplant recipient and how spontaneous decompression due to pneumothorax led to clinical improvement in our patient. | Himanshu Deshwal Subha Ghosh Kathleen Hogan Olufemi Akindipe Charles Randall Lane Atul C Mehta | 2020 | World Journal of Clinical Cases2020，8，14： | 0 |
| 5 | New Nodule-Newer Etiology显示文摘AIM: To evaluate frequency and temporal relationship between pulmonary nodules(PNs) and transbronchial biopsy(TBBx) among lung transplant recipients(LTR). METHODS: We retrospectively reviewed 100 records of LTR who underwent flexible bronchoscopy(FB) with TBBx, looking for the appearance of peripheral pulmonary nodule(PPN). If these patients had chest radiographs within 50 d of FB, they were included in the study. Data was compared with 30 procedures performed among non-transplant patients. Information on patient's demographics, antirejection medications, anticoagulation, indication and type of lung transplantation, timing of the FB and the appearance and disappearance of the nodules and its characteristics were gathered.RESULTS: Nineteen new PN were found in 13 procedures performed on LTR and none among nontransplant patients. Nodules were detected between 4-47 d from the procedure and disappeared within 84 d after appearance without intervention.CONCLUSION: FB in LTR is associated with development of new, transient PPN at the site of TBBxin 13% of procedures. We hypothesize that these nodules are related to local hematoma and impaired lymphatic drainage. Close observation is a reasonable management approach. | Atul C Mehta Juan Wang Sami Abuqayyas Puneet Garcha Charles Randy Lane Wayne Tsuang Marie Budev Olufemi Akindipe | 2016 | World Journal of Transplantation2016，6，1： | 0 |
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