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| 1 | Comparisons of blood biochemical parameters,digestive enzyme activities and volatile fatty acid profile between Meishan and Yorkshire piglets显示文摘This study was conducted to compare physiological characteristics between Meishan and Yorkshire piglets in their early lives. Six healthy purebred Meishan sows and Yorkshire sows with close farrowing dates were used in this research. The piglets sucked their respective sow’s milk for 14 days, then they were slaughtered to collect samples of blood, pancreas, contents of stomach, jejunum, cecum, colon as well as feces for analysis of blood biochemical parameters, digestive enzymes, and volatile fatty acid(VFA). The results showed that Yorkshire piglets had higher concentrations of high-density lipoprotein cholesterol(HDL-C) and total cholesterol(TC)(P < 0.05). Gastric lipase activity was higher in Meishan piglets but Yorkshire piglets had higher lactase activity(P < 0.05). The total VFA together with acetate and propionate in cecum and colon were higher in Meishan piglets than in Yorkshire piglets(P < 0.05),but acetate in jejunum and ratio of acetate to propionate in colon were lower in Meishan piglets than in Yorkshire piglets(P < 0.05). In conclusion, in early suckling period, significant differences exist in host metabolism and intestinal microbial metabolism between Meishan and Yorkshire piglets. | Shouqing Ma Meilei Ma Chunlong Mu Kaifan Yu Weiyun Zhu | 2015 | Animal Nutrition2015，，4： | 2 |
| 2 | Curcumin prevents diabetic cardiomyopathy in streptozotocin-induced diabetic rats: Possible involvement of PKC–MAPK signaling pathway显示文摘 | Vivian Soetikno Flori R. Sari Vijayakumar Sukumaran Arun Prasath Lakshmanan Sayaka Mito Meilei Harima Rajarajan A. Thandavarayan Kenji Suzuki Masaki Nagata Ritsuo Takagi Kenichi Watanabe | 2012 | European Journal of Pharmaceutical Sciences2012，，3： | 2 |
| 3 | rSac3, a novel Sac domain phosphoinositide phosphatase, promotes neurite outgrowth in PC12 cells显示文摘囊包含域的蛋白质属于 phosphoinositide 磷酸酶(PIPPase 家庭) 的一个最新识别的家庭。尽管有描绘得好的酶的活动,这个哺乳动物的囊领域 PIPPase 家庭的生物功能仍然保持大部分未知。我们识别了新奇的囊包含域的蛋白质,老鼠 Sac3 (rSac3 ) 它是广泛地在各种各样的纸巾表示了并且对 endoplasmic 蜂窝胃局部性, Golgi 复杂、再循环的内涵体。rSac3 在 vitro 作为底层与 PI (3 ) P, PI (4 ) P 和 PI (3,5 ) P (2 ) 显示 PIPPase 活动,并且在囊域的催化核心的一个变化废除它的酶的活动。rSac3 的表示起来在刺激的神经生长因素(NGF ) 期间调整了 PC12 细胞 neuronal 区别,并且在这的表示上,蛋白质在 PC12 细胞支持神经突长出。相反地,由反感觉 oligonucleotides 的 rSac3 表示的抑制减少刺激 NGF 的 PC12 房间的神经突长出,并且 rSac3 的活跃地点变化消除它的 neurite-outgrowth-promoting 活动。这些结果显示 rSac3 在通过它的 PIPPase 活动区分神经原支持神经突长出,建议囊领域 PIPPase 蛋白质可以参予从到血浆膜的 endoplasmic 蜂窝胃和 Golgi 建筑群的前面的膜交通国王,并且可以作为 neuronal 房间生长和区别的这个关键过程的管理者工作。 | Yiyuan Yuan Xiang Gao Ning Guo Hui Zhang Zhiqin Xie Meilei Jin Baoming Li LeiYu Naihe Jing | 2007 | Cell Research2007，17，11： | 1 |
| 4 | Curcumin attenuates hyperglycaemia-mediated AMPK activation and oxidative stress in cerebrum of streptozotocin-induced diabetic rat显示文摘 | Arun Prasath Lakshmanan Kenichi Watanabe Rajarajan A. Thandavarayan Flori R. Sari Harima Meilei Vivian Soetikno Somasundaram Arumugam Vijayasree V. Giridharan Kenji Suzuki Makoto Kodama | 2011 | Free Radical Research2011，，7： | 1 |
| 5 | Effects of V2-receptor antagonist tolvaptan and the loop diuretic furosemide in rats with heart failure 显示文摘 | Punniyakoti T V Kenichi W Meilei M | 2008 | Biochem Pharmaco12008，75，： | 1 |
| 6 | Swimming stress in DN 14-3-3 mice triggers maladaptive cardiac remodeling:Role of p38 MAPK显示文摘 | KEN-ICHI WATANABE MEILEI M A KEN ICHI HIRA- BAYASHI | 2007 | Am J Physiol Heart Circ Physiol2007，292，： | 1 |
| 7 | Generation of monoclonal antibodies against n-3 fatty acid desaturase显示文摘Dear Editor:Omega-3 polyunsaturated fatty acids(n-3 PUFAs)are essential fatty acids for normal cellular functions and have been used for prevention and treatment of many diseases,including coronary heart disease,diabetes,and cancers[1-3].n-3 PUFAs and n-6 PUFAs have been shown to decrease and increase the severity of several human diseases,respectively[4].Unfortunately,mammals have no enzymes to synthesize n-6 and | Yanfei Zhang Yilin Yuan Meilei Sheng Wei Zhang Ying Wang Xiao Zhang Yifan Dai | 2015 | The Journal of Biomedical Research2015，29，6： | 0 |
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