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| 1 | Galectin-1-mediated biochemical controls of melanoma and glioma aggressive behavior显示文摘Gliomas and melanomas are associated with dismal prognosis because of their marked intrinsic resistance to proapoptotic stimuli,such as conventional chemotherapy and radiotherapy,as well as their ability to escape immune cell attacks.In addition,gliomas and melanomas display pronounced neoangiogenesis.Galectin-1 is a hypoxia-sensitive protein,which is abundantly secreted by glioma and melanoma cells,which displays marked proangiogenic effects.It also provides immune tolerogenic environments to melanoma and glioma cells through the killing of activated T cells that attack these tumor cells.Galectin-1 protects glioma and melanoma cells against cytotoxic insults(including chemotherapy and radiotherapy) through a direct role in the unfolded protein response.Altogether,these facts clearly point to galectin-1 as an important target to be combated in gliomas and melanomas in order to:(1) weaken the defenses of these two types of cancers against radiotherapy,chemotherapy and immunotherapy/vaccine therapy;and(2) reinforce antiangiogenic therapies.In the present article,we review the biochemical and molecular biology-related pathways controlled by galectin-1,which are actually beneficial for melanoma and glioma cells,and therefore detrimental for melanoma and glioma patients. | Florence Lefranc Véronique Mathieu Robert Kiss | 2011 | World Journal of Biological Chemistry2011，2，9： | 6 |
| 2 | In Situ Dynamics of Microbial Communities during Decomposition of Wheat,Rape,and Alfalfa Residues显示文摘 | Pascault N Cécillon L Mathieu O Hénault C Sarr A Lév(e)que J Fatty P Ranjard L Maron PA | | 0，，04： | 1 |
| 3 | Cell-permeable peptides induce dose-and length-dependent cytotoxic effects 显示文摘 | Cardozo AK Buchillier V Mathieu M Chen J Ortis F Ladriere L | 2007 | Biochim Biophys Acta2007，1768，9： | 1 |
| 4 | Identification ofdifferentially expressed genes in a porcine in vivo model ofadipogenesis using suppression subtractive hybridization 显示文摘 | Labrecque B Mathieu 0 Bordignon V | 2009 | Comp Biochem PHys D2009，4，： | 1 |
| 5 | Service strategies within the manufacturing sector: Benefit, costs and partnership 显示文摘 | Mathieu V | 2001 | International Journal of Service Industry Management2001，12，5： | 1 |
| 6 | In Search of a Cytostatic Agent Derived from the Alkaloid Lycorine:Synthesis and Growth Inhibitory Properties of Lycorine Derivatives显示文摘 | EVDOKIMOVA N M LAMORAL-THEYSB D MATHIEU V | 2011 | Bioorganic&Medicinal Chemistry2011，19，23： | 1 |
| 7 | AKT involvement in cispla- tin chemoresistance of human uterine cancer cells显示文摘 | Gagnon V Mathieu 1 Sexton E | 2004 | Gyneeol Oncol2004，94，3： | 1 |
| 8 | Variationof the ultrasonic response of a dental implant embe-dded in tricalcium silicate-based cement under cyclicloading显示文摘 | Vayron R Karasinski P Mathieu V | 2013 | J Biomech2013，46，6： | 1 |
| 9 | Galectins and gli- omas显示文摘 | Le MM Fortin S Mathieu V et aI | 2010 | BrainPathol2010，20，1： | 1 |
| 10 | Recent advance in techniques for hyperspectral image processing显示文摘 | Antonio P Jon A B Joseph W B Jason B Lorenzo B Gustavo C V Jocelyn C Mathieu F Paolo G Anthony G Mattia M James C T Giovanna T | 2009 | Remote Sensing of Environment2009，113，： | 1 |
| 11 | Benign Liver Tumors显示文摘 | Mathieu D Vilgrain V Mahfouz AE | 1997 | Magn Reson Imaging Clin N Am1997，5，2： | 1 |
| 12 | Mutual antagonistic relationship between prostaglandin E(2) and IFN-gamma:Implications for rheumatoid arthritis显示文摘 | Mathieu M C Lord-Dufour S Bernier V | 2008 | Eur J Immunol2008，38，7： | 1 |
| 13 | Influence of time elapsed between myocardial infarction and coronary artery bypass grafting surgery on operative mortality显示文摘 | Pierre V Mathieu P Doyle D | | 0，，03： | 1 |
| 14 | Managing learning in informal innovation network: overcoming the Daphne - dilemma 显示文摘 | Joan E Aken V Mathieu P W | 2000 | R&D Management2000，30，2： | 1 |
| 15 | A reflective film for improving colour 显示文摘 | Mathieu V | 2000 | Apple2000，160，： | 1 |
| 16 | Standardized way for imaging of the sagittal spinal balance显示文摘 | Morvan G Mathieu P Vuillemin V | 2011 | Eur Spine J2011，20，： | 1 |
| 17 | Service Strategies within the Manufacturing Sector: Benefits, Costs and Partnership 显示文摘 | Mathieu V | 2001 | International Journal of Service Industry Management2001，12，5： | 1 |
| 18 | Comparison of theeffects of sucrose and hexose on furfural formation and browning incookies baked at different temperatures显示文摘 | AMEUR L A MATHIEU O LALANNE V | 2007 | Food Chemistry2007，101，4： | 1 |
| 19 | Product Services :from a Service Supporting the Product to a Service Supporting the Client 显示文摘 | Mathieu V | 2001 | Journal of Business & Industrial Marketing2001，16，1： | 1 |
| 20 | Product Services:from a Service Supporting the Product to a Service Supporting the Client显示文摘 | MATHIEU V | 2001 | Journal of Business & Industrial Marketing2001，16，1： | 1 |
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