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2篇 您的检索式:作者名="Marsha R. ROSNER"
    题名 作者 年代 出处 被引量
1Modulation of the MAP kinase signaling cascade by Raf kinase inhibitory protein显示文摘Proteins like Raf kinase inhibitory protein (RKIP) that serve as modulators of signaling pathways, either by promoting or inhibiting the formation of productive signaling complexes through protein-protein interactions, have been demon- strated to play an increasingly important role in a number of cell types and organisms. These proteins have been implicated in development as well as the progression of cancer. RKIP is a particularly interesting regulator, as it is a highly conserved, ubiquitously expressed protein that has been shown to play a role in growth and differentiation in a number of organisms and can regulate multiple signaling pathways. RKIP is also the first MAP kinase signaling modulator to be identified as playing a role in cancer metastasis, and identification of the mechanism by which it regulates Raf-1 activation provides new targets for therapeutic intervention.Nicholas TRAKUL Marsha R. ROSNER 2005Cell Research2005,15,1:25
2Raf Kinase Inhibitory Protein Regulates Aurora B Kinase and the Spindle Checkpoint显示文摘Eva M. Eves Paul Shapiro Karuna Naik Ulf R. Klein Nicholas Trakul Marsha Rich Rosner 2006Molecular Cell2006,,4:1
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