|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Genetics of coronary artery disease and myocardial infarction显示文摘Atherosclerotic coronary artery disease(CAD) comprises a broad spectrum of clinical entities that include asymptomatic subclinical atherosclerosis and its clinical complications, such as angina pectoris, myocardial infarction(MI) and sudden cardiac death. CAD continues to be the leading cause of death in industrialized society. The long-recognized familial clustering of CAD suggests that genetics plays a central role in its development, with the heritability of CAD and MI estimated at approximately 50% to 60%. Understanding the genetic architecture of CAD and MI has proven to be difficult and costly due to the heterogeneity of clinical CAD and the underlying multi-decade complex pathophysiological processes that involve both genetic and environmental interactions. This review describes the clinical heterogeneity of CAD and MI to clarify the disease spectrum in genetic studies, provides a brief overview of the historical understanding and estimation of the heritability of CAD and MI, recounts major gene discoveries of potential causal mutations in familial CAD and MI, summarizes CAD and MIassociated genetic variants identified using candidate gene approaches and genome-wide association studies(GWAS), and summarizes the current status of the construction and validations of genetic risk scores for lifetime risk prediction and guidance for preventive strategies. Potential protective genetic factors against the development of CAD and MI are also discussed. Finally, GWAS have identified multiple genetic factors associated with an increased risk of in-stent restenosis following stent placement for obstructive CAD. This review will also address genetic factors associated with in-stent restenosis, which may ultimately guide clinical decision-making regarding revascularization strategies for patients with CAD and MI. | Xuming Dai Szymon Wiernek James P Evans Marschall S Runge | 2016 | World Journal of Cardiology2016，8，1： | 15 |
| 2 | GRIMSEL现场的气体渗透试验(英文)显示文摘自 1976 年以来,日本核废料管理基金会与研究中心(RWMC)一直在进行核废料处置的研究。最近,RWMC非常关注核废料处置库的监测、遥控以及现场勘查技术等重要的社会公众与技术问题。其中,处置库溢出气体是一项重要的安全可靠性评估项目。这项名为“工程屏障的气体渗透试验”(GMT)的研究是在瑞士 Nagra 的 Grimsel现场实验室进行的。GMT 集中研究在粮仓形的处置库中由核废料产生的气体在工程屏障中的渗透问题。在 Grimsel现场,一个按比例缩小的工程屏障库由一个具有透气孔的混凝土仓和砂–膨润土缓冲材料组成,缓冲材料被放置在一个专门建造的洞室中。混凝土仓直径为 2.5 m,高为 2.5 m,放置在直径为 4 m 的从上到下开挖而成的竖井中。在工程屏障饱和及水渗透试验之后,气体分两个阶段被注入地窖中。气体第一次被注入之后,重复进行水渗透试验,以便观察工程屏障库的变化。第二次气体注入的时候,在工程屏障及岩石圈中采用一种可以多点取样的鸡尾酒气体跟踪器。在气体注入之后,小心挖掘出工程屏障库,然后用各种方法来进行鉴定,并采用实验室以及建模程序来进行现场的模拟研究。 | Fujiwara A Okamoto S Tsuboya T Vomvoris S Marschall P Ando K Shimura T | 2006 | 岩石力学与工程学报2006，25，4： | 2 |
| 3 | Characteristics and prognosis of myocardial infarction in patients with normal coronary arteries显示文摘 | Ammann P Marschall S | 2000 | Chest2000，117，： | 1 |
| 4 | Lcysteine on Ag (111):A combined STM and X-ray spectroscopy study of anchorage and deprotonation显示文摘 | Fischer S Papageorgiou A C Marschall M | | 0，，38： | 1 |
| 5 | Characteristics and prognosis of myocardial infarction in patients with normal coronary arteries显示文摘 | Ammann P Marschall S Kraus M | 2000 | Chest2000，117，2： | 1 |
| 6 | Cardiac troponin T in chest pain unit patients without ischemic electrocardiographic changes: angiographic correlates and long-term clinical outcomes显示文摘 | Christopher R deFilippi Monica Tocchi Rohit J Parmar Salvatore Rosanio Gerard Abreo Marjorie A Potter Marschall S Runge Barry F Uretsky | 2000 | Journal of the American College of Cardiology2000，，7： | 1 |
| 7 | Antibiotic prophylaxis for urinary tract infections after removal of urinary catheter:meta-analysis显示文摘 | Marschall J Christopher RC Fowler S | 2013 | BMJ2013，346，： | 1 |
| 8 | Impact of fatty liver disease on health care utilization and costs in a general population:a 5-year observation显示文摘 | Baumeister S E Volzke H Marschall P | 2012 | Gastroenterology2012，134，1： | 1 |
| 9 | Intrahepatic Cholestasis of Pregnancy显示文摘 | Lammert F Marschall HU Matern S | 2003 | Curr Treat Options Gastroenterol2003，6，： | 1 |
| 10 | Angiotensin induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-κB transcription factors显示文摘 | Youqi Han Marschall S Runge | 1999 | Circulation1999，84，： | 1 |
| 11 | CLEVER:cliqueenumerating variant finder显示文摘 | Marschall T Costa I G Canzar S | 2012 | Bioinformatics2012，28，22： | 1 |
| 12 | Optical coherence tomography-current technology and applications in clinical and biomedical research 显示文摘 | Marschall S Sander B Mogensen M Jrgensen TM Andersen PE | 2011 | Anal Bioanal Chem2011，400，9： | 1 |
| 13 | Oxidative stress and vascular disease显示文摘 | Nageswara R Aleksandr V Marschall S | 2005 | Arterioscler Thromb Vasc Biol2005，25，1： | 1 |
| 14 | Randomized comparison of a strategy of predischarge coronary angiography versus exercise testing in low-risk patients in a chest pain unit: in-hospital and long-term outcomes显示文摘 | Christopher R deFilippi Salvatore Rosanio Monica Tocchi Rohit J Parmar Marjorie A Potter Barry F Uretsky Marschall S Runge | 2001 | Journal of the American College of Cardiology2001，，8： | 1 |
| 15 | An algorithm to compute the character access count distribution for pattern matching algorithms显示文摘 | Marschall T Rahmann S | 2011 | Algorithms2011，4，4： | 1 |
| 16 | Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma 显示文摘 | Schulte JH Marschall T Martin M Rosenstiel P Mestdagh P Schlierf S | 2010 | Nucleic Acids Res2010，38，17： | 1 |
| 17 | Oxidative stress and vascular disease显示文摘 | Nageswara R Aleksandr V Marschall S | 2005 | Arterioscler Thromb Vasc Biol2005，25，1： | 1 |
| 18 | Sudden cardiac death in a teenager:a review of Kawasaki Disease显示文摘 | Rung E Marschall S | 1998 | Am J Med Sci1998，315，： | 1 |
| 19 | Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells显示文摘 | Benckert C Jonas S Cramer T Von Marschall Z Schafer G Peters M | 2003 | Cancer Res2003，63，5： | 1 |
| 20 | Characteristics and prognosis of myocardial infarction in patients with normal coro- nary arteries显示文摘 | Ammann P Marschall S Kraus M | 2000 | Chest2000，117，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员