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63篇 您的检索式：作者名="Matern S"

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	题名	作者	年代	出处	被引量
1	Cholesterol crystal binding of biliary immunoglobulin A: visualization by fluorescence light microscopy显示文摘AIM To assess potential contributions of biliary IgA for crystal agglomeration into gallstones, we visualized cholesterol crystal binding of biliary IgA.METHODS Crystal-binding biliary proteins were extracted from human gallbladder bile using lectin affinity chromatography. Biliary IgA was isolated from the bound protein fraction by immunoaffinity chromatography. Pure cholesterol monohydrate crystals were incubated with biliary IgA and fluoresceine isothiocyanate (FITC)-conjugated anti-lgA at 37C. Samples were examined under polarizing and fluorescence light microscopy with digital image processing.RESULTS Binding of biliary IgA to cholesterol monohydrate crystals could be visualized with FITC-conjugated anti-lgA antibodies. Peak fluorescence occurred at crystal edges and dislocations. Controls without biliary IgA or with biliary IgG showed no significant fluorescence.CONCLUSION Fluorescence light microscopy provided evidence for cholesterol crystal binding of biliary IgA. Cholesterol crystalbinding proteins like IgA might be important mediators of crystal agglomeration and growth of cholesterol gallstones by modifying the evolving crystal structures in vivo.	Frank Lammert Stefan Südfeld Norbert Busch Siegfried Matern	2001	World Journal of Gastroenterology2001，7，2：	6
2	Genetic risk factors for hepatic fibrosis in chronic liver diseases 显示文摘	WASMUTH HE LAMMERT F MATERN S	2003	Med Klin2003，98，12：	1
3	Biliary secretory immunoglobulin A is a major of the new group of cholesterol crystal-binding proteins显示文摘	Busch N Lammert F Matern S	1998	Gastroenterology1998，115，1：	1
4	Radioassay of UDP-glucuronosyl- transferase activities towards endogenous substrates using labeled UDP- glucnronic acid and an organic solvent extraction procedure显示文摘	Matern H Heinemann H Matern S	1994	Analytical Biochemistry1994，219，：	1
5	Multidrug resis-tance and response to antiretroviral treatment显示文摘	DIETRICH C G GEIER A MATERN S	2002	Lancet2002，359，9323：	1
6	Matrixmetalloproteinases and colorectal cancer显示文摘	Roeb E Matern S	2003	Med Klin2003，98，12：	1
7	Adrenal ganglioneuroma 显示文摘	Maweja S Materne R Detrembleur N	2007	Am J Surg2007，194，：	1
8	Carnitine deficiency in OCTN2-/-newborn mice leads to a severe gut and immune phenotype with widespread atrophy, apoptosis and a pro-inflammatory response显示文摘	Sonne S Shekhawat PS Matern D	2012	PLoS One2012，7，47：	1
9	Reduction of the false- positive rate in newborn screening by implementation of MS/MS- based second-tier tests: the Mayo Clinic experience (2004-2007) 显示文摘	Matern D Tortorelli S Oglesbee D	2007	J Inherit Metab Dis2007，30，4：	1
10	The effect of short fatty acids on calcium flux rates across isolated rumen epithelium of hay-fed and con-centrate-fed sheep显示文摘	Uppal S K Wolf K Materns H	2003	Journal of Animal Physiology and Animal Nutrition2003，87，12：	1
11	Spontaneous development of intestinal and colonic atrophy and inflammation in the carnitine-de?cient jvs (OCTN2-/-) mice 显示文摘	Shekhawat P S Srinivas S R Matern D	2007	Mol Genet Metab2007，92，：	1
12	Intrahepatic Cholestasis of Pregnancy显示文摘	Lammert F Marschall HU Matern S	2003	Curr Treat Options Gastroenterol2003，6，：	1
13	Safety,hazards and ergonomics in the operating room显示文摘	Matern U Koneczny S		0，，：	1
14	Matrix matelloproteinases and colorectal cancer显示文摘	Roeb E Matern S	2003	Med Klin(Munich)2003，98，12：	1
15	Extracellular matrix-from basic research to clinical significance:an overview with special consideration of matrix metalloproteinases 显示文摘	Hamacher S Matern S Roeb E	2004	Dtsch Med Wochenschr2004，129，38：	1
16	Matrix metalloproteinases and colorectal cancer显示文摘	Roeb E Matern S	2003	Med Klin (Munich)2003，98，12：	1
17	Adrenal ganglioneuroma 显示文摘	Maweja S Materne R Detrembleur N	2007	Am J Surg2007，194，：	1
18	Prediction of gestational diabetes mellitus by soluble (pro)renin receptor during the first trimester显示文摘	Maternal diabetes Watanabe N Morimoto S Fujiwara T	2013	J Clin Endocrinol Metab2013，98，6：	1
19	Intrahepatic Cholestasis of Pregnancy显示文摘	Lammert F Marschall HU Matern S	2003	Curr Treat Options Gastroenterol2003，6，2：	1
20	Transcriptome sequencing of lentil based on secondgeneration technology permits large-scale unigene assembly and SSR marker discovery 显示文摘	Kaur S Cogan NO Pembleton L W Shinozuka M Savin K W Materne M Forster J W	2011	BMG Genomics2011，12，：	1

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