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6篇 您的检索式:作者名="Mark Humayun"
    题名 作者 年代 出处 被引量
1Outcomes of 140 Consecutive Cases of 25-Gauge Transconjunctival Surgery for Posterior Segment Disease显示文摘Rohit R. Lakhanpal Mark S. Humayun Eugene de Juan Jennifer I. Lim Lawrence P. Chong Tom S. Chang Michael Javaheri Gildo Y. Fujii Aaron C. Barnes Terry J. Alexandrou 2005Ophthalmology2005,,5:1
2Characteristics of visual loss by scanning laser ophthalmoscope microperimetry in eyes with subfoveal choroidal neovascularization secondary to age-related macular degeneration显示文摘Gildo Y Fujii Eugene De Juan Mark S Humayun Janet S Sunness Tom S Chang Juliana V Rossi 2003American Journal of Ophthalmology2003,,6:1
3Natural course of experimental retinal vein occlusion in rabbit; arterial occlusion following venous photothrombosis显示文摘Hossein Ameri Tanapat Ratanapakorn Narsing A. Rao Gerald J. Chader Mark S. Humayun 2008Graefe’s Archive for Clinical and Experimental Ophthalmology2008,,10:1
4Visual perception in a blind subject with a chronic microelectronic retinal prosthesis显示文摘Mark S. Humayun James D. Weiland Gildo Y. Fujii 0,,24:1
5Introcular retinal prosthesis 显示文摘MARK S HUMAYUN M S 2001Transactions of American Ophthalmological Society2001,99,1018:1
6ecent Advances in the Science of Burst Wave Lithotripsy and Ultrasonic Propulsion显示文摘Objective.Retinal degeneration involving progressive deterioration and loss of function of photoreceptors is a major cause of permanent vision loss worldwide.Strategies to treat these incurable conditions incorporate retinal prostheses via electrically stimulating surviving retinal neurons with implanted devices in the eye,optogenetic therapy,and sonogenetic therapy.Existing challenges of these strategies include invasive manner,complex implantation surgeries,and risky gene therapy.Methods and Results.Here,we show that direct ultrasound stimulation on the retina can evoke neuron activities from the visual centers including the superior colliculus and the primary visual cortex(V1),in either normal-sighted or retinal degenerated blind rats in vivo.The neuron activities induced by the customized spherically focused 3.1 MHz ultrasound transducer have shown both good spatial resolution of 250μm and temporal resolution of 5 Hz in the rat visual centers.An additional customized 4.4 MHz helical transducer was further implemented to generate a static stimulation pattern of letter forms.Conclusion.Our findings demonstrate that ultrasound stimulation of the retina in vivo is a safe and effective approach with high spatiotemporal resolution,indicating a promising future of ultrasound stimulation as a novel and noninvasive visual prosthesis for translational applications in blind patients.Xuejun Qian Gengxi Lu Biju B.Thomas Runze Li Xiaoyang Chen K.Kirk Shung Mark Humayun Qifa Zhou 2022Biomedical Engineering Frontiers2022,3,1:0
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