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    题名 作者 年代 出处 被引量
1中国人口政策对生育率的影响显示文摘本文利用超生罚款数额来测度县级人口控制的强度,并以此估算人口控制对生育率的影响。研究发现,现有的罚款政策平均降低每位农村妇女0.33的累计生育率;罚敖对低收入家庭影响较大;另外,限制农村劳动力流动有显著的刺激生育作用。杨涛 Marjorie McElroy 孙征 2000中国人口科学2000,,3:19
2组织间和组织内知识转移:对其前因后果的元分析及评估显示文摘当前,学术界对组织知识转移的研究方兴未艾,但我们对其前因后果的理解依然相当含糊。尽管已经有人对组织知识转移的文献进行了概念性的定性回顾,但目前还没有人对已有的定量研究结果进行总结。为了实现这个目标,本文首先利用元分析方法考察了知识、组织和网络等不同前因变量是如何影响组织知识转移的;然后,对现有的关于知识转移及其后果之间关系的研究进行了整合;最后,论证了组织间和组织内的情境因素、知识转移的方向性以及测量特性对所研究关系的调节作用。通过收集和归纳现有研究结论,本文不仅对组织知识转移的途径和结果提出了新见解,还指明了未来的研究方向。Raymond van Wijk Justin J.P.Jansen Marjorie A.Lyles 毕克贵 2012管理世界2012,28,4:19
3Physiological Responses of Contrasting Rice Genotypes to Salt Stress at Reproductive Stage显示文摘Salinity is a major abiotic stress affecting plant growth and productivity. Considerable genetic variation is present in rice in response to salt stress, with higher sensitivity during early seedling and reproductive stage. In this study, physiological changes in leaves and developing panicles of rice genotypes (IR686, Sadri, Rc222, CSR28, IR670 and Pokkali) contrasting in salt tolerance at the reproductive stage were evaluated in greenhouse experiment under salt stress. The results showed that IR670 and the tolerant-check Pokkali maintained lower Na^+/K^+ ratio, less reduction in chlorophyll concentration, lower malondialdehyde (MDA) production, higher concentrations of reduced ascorbate (reduced AsA), higher proline accumulation and lower percentage reduction in pollen viability than the salt-sensitive genotypes under salt stress. The higher concentration of reduced AsA suggests an efficient ROS-scavenging system. Physiological measurements and pollen viability analysis revealed that Sadri (moderately tolerant at the seedling stage) is sensitive to salt stress at the flowering stage. The findings will be useful in breeding salt tolerant varieties at both seedling and reproductive stages by selecting appropriate genotypes and phenotypes.Maria Elisa B.GERONA Marjorie P. DEOCAMPO James A.EGDANE Abdelbagi M.ISMAIL Maribel L. DIONISIO-SESE 2019Rice science2019,26,4:9
4睾丸后精子成熟,不育与高胆固醇血症显示文摘胆固醇是参与哺乳动物生理活动的重要分子,由于它是固醇类激素合成的通用前体物质,因而对生殖系统尤为重要。胆固醇不仅仅对于配子发生起到重要作用,它也是公认的精子功能的调节分子。胆固醇体内平衡的调节对睾丸后精子的成熟至关重要,胆固醇水平失衡会影响到睾丸后调控事件。代谢性脂质紊乱(血脂异常症)会影响男性的生育能力,但大多数这方面的研究是从内分泌/睾丸的角度进行探讨的,而这篇综述将关注像高胆固醇血症这样的特定血脂异常症在哺乳动物精子的睾丸后成熟过程中的有害影响。Marjorie Whitfield Xavier PoUet-Villard Rachel Levy Joel R Drevet Fabrice Saez 2015Asian Journal of Andrology2015,17,5:8
5Glucocorticosteroid therapy in inflammatory bowel diseases: From clinical practice to molecular biology显示文摘Inflammatory bowel diseases(IBDs),such as ulcerative colitis and Crohn's disease,are chronic pathologies associated with a deregulated immune response in the intestinal mucosa,and they are triggered by environmental factors in genetically susceptible individuals.Exogenous glucocorticoids(GCs)are widely used as anti-inflammatory therapy in IBDs.In the past,patients with moderate or severe states of inflammation received GCs as a first line therapy with an important effectiveness in terms of reduction of the disease activity and the induction of remission.However,this treatment often results in detrimental side effects.This downside drove the development of second generation GCs and more precise(non-systemic)drugdelivery methods.Recent clinical trials show that most of these new treatments have similar effectiveness to first generation GCs with fewer adverse effects.The remaining challenge in successful treatment of IBDs concerns the refractoriness and dependency that some patients encounter during GCs treatment.A deeper understanding of the molecular mechanisms underlying GC response is key to personalizing drug choice for IBDs patients to optimize their response to treatment.In this review,we examine the clinical characteristics of treatment with GCs,followed by an in depth analysis of the proposed molecular mechanisms involved in its resistance and dependence associated with IBDs.This thorough analysis of current clinical and biomedical literature may help guide physicians in determining a course of treatment for IBDs patients and identifies important areas needing further study.Karen Dubois-Camacho Payton A Ottum Daniel Franco-Munoz Marjorie De la Fuente Alejandro Torres-Riquelme David Díaz-Jiménez Mauricio Olivares-Morales Gonzalo Astudillo Rodrigo Quera Marcela A Hermoso 2017World Journal of Gastroenterology2017,23,36:6
6Interprofessional, multiple step simulation course improves pediatric resident and nursing staff management of pediatric patients with diabetic ketoacidosis显示文摘AIM To investigate the use of a multidisciplinary, longitudinal simulation to educate pediatric residents and nurses on management of pediatric diabetic ketoacidosis.METHODS A multidisciplinary, multiple step simulation course was developed by faculty and staff using a modified Delphi method from the Pediatric Simulation Center and pediatric endocrinology department. Effectiveness of the simulation for the residents was measured with a pre- and post-test and a reference group not exposed to simulation. A follow up post-test was completed 3-6 mo after the simulation. Nurses completed a survey regarding the education activity. RESULTS Pediatric and medicine-pediatric residents(n = 20) and pediatric nurses(n = 25) completed the simulation course. Graduating residents(n = 16) were used as reference group. Pretest results were similar in the control and intervention group(74% ± 10% vs 76% ± 15%, P = 0.658). After completing the intervention, participants improved in the immediate post-test in comparison to themselves and the control group(84% ± 12% post study; P < 0.05). The 3-6 mo follow up post-test results demonstrated knowledge decay when compared to their immediate post-test results(78% ± 14%, P = 0.761). Residents and nurses felt the interdisciplinary and longitudinal nature of the simulation helped with learning.CONCLUSION Results suggest a multidisciplinary, longitudinal simulation improves immediate post-intervention knowledge but important knowledge decay occurs, future studies are needed to determine ways to decrease this decay.Linnea M Larson-Williams Amber Q Youngblood Dawn Taylor Peterson J Lynn Zinkan Marjorie L White Hussein Abdul-Latif Leen Matalka Stephen N Epps Nancy M Tofil 2016World Journal of Critical Care Medicine2016,5,4:4
7硫醇转移酶基因敲除小鼠模型的建立及其白内障形成机制显示文摘目的:通过建立硫醇转移酶(TTase)基因敲除小鼠模型,观察其晶状体形态和生化方面随年龄的改变,探讨TTase在晶状体氧化还原系统中的重要作用及参与年龄相关性白内障形成的机制。方法:建立TTase基因敲除小鼠模型并进行基因型鉴定。裂隙灯观察TTase基因敲除型和野生型小鼠白内障随年龄的发生情况。检测小鼠晶状体中谷胱甘肽(GSH)含量。Western blot检测晶状体中氧化产物蛋白质二硫化物(PSSG)的变化。免疫共沉淀法鉴定形成PSSG的蛋白质。观察纯化的重组人晶状体TTase(RHLT)对PSSG的脱硫醇作用。结果:TTase基因敲除型小鼠和野生型小鼠白内障的发生均随年龄而增加,且主要表现为核性白内障。在TTase基因敲除型小鼠中,白内障最早从4月龄开始发生,9月龄时最为显著;野生型小鼠白内障最早从9月龄开始发生,12月龄时最为显著。两种基因型小鼠晶状体中GSH含量均随年龄增加而下降,9月龄TTase基因敲除型小鼠晶状体中GSH下降更为显著,且PSSG的表达明显高于野生型,主要表现为高分子聚合物。免疫共沉淀反应证实形成PSSG的蛋白质包含肌动蛋白(actin)和三磷酸甘油醛脱氢酶(GAPDH),这种积聚的PSSG可被GSH还原,且与纯化的RHLT反应更有效。结论:TTase基因敲除可以加速小鼠年龄相关性白内障的发生,这与晶状体中PSSG的积聚相关,且形成的PSSG可被TTase脱硫醇,证实TTase在防止年龄相关性白内障的发生中发挥重要作用。张婕 严宏 Marjorie F.Lou 2020国际眼科杂志2020,20,3:4
8Risk of ventricular arrhythmia in patients with myocardial infarction and non-obstructive coronary arteries and normal ejection fraction显示文摘AIM To assess the arrhythmic determinants and prognosis of patients presenting with myocardial infarction and nonobstructive coronary arteries(MINOCA)with normal ejection fraction(EF).METHODS This is an observational analysis of 131 MINOCA patients with normal EF.Three cardiac magnetic resonance(CMR)diagnosis classes were recognized according to the late gadolinium enhancement(LGE)pattern:Myocardial infarction(MI)(n=34),myocarditis(n=47),and'no LGE'(n=50).Ventricular events occurring during hospitalization were recorded and the entire population was followed-up at 1 year.RESULTS Ventricular arrhythmia was observed in 18(13.8%)patients during hospitalization.The'no LGE'patients experienced fewer ventricular events than the MI and myocarditis patients[4.0%vs 26.5%and 14.9%,respectively(P=0.013)].There was no significant difference between the MI and myocarditis groups.On multivariate analysis,LGE transmural extent[OR=1.52(1.08-2.15),P=0.017]and ST-segment elevation[OR=4.65(1.61-13.40),P=0.004]were independent predictors of ventricular arrhythmic events,irrespective of the diagnosis class.Finally,no patient experienced sudden cardiac death or ventricular arrhythmia recurrence at 1-year.CONCLUSION MINOCA patients with normal EF presented no 1-year cardiovascular events,irrespective of the CMR diagnosis class.LGE transmural extent and ST segment elevation at admission are risk markers of ventricular arrhythmia during hospitalization.Loic Bière Marjorie Niro Hervé Pouliquen Jean-Baptiste Gourraud Fabrice Prunier Alain Furber Vincent Probst 2017World Journal of Cardiology2017,9,3:3
9Absorptive capacity, learning, and performance in international joint ventures显示文摘Peter J.Lane Jane E.Salk Marjorie A.Lyles 2001Strat Mgmt J2001,,12:3
10中大西洋被动大陆边缘的热演化——一个中生代超级地幔柱上的大陆裂解实例显示文摘沿北美和西非被动大陆边缘,一个近同期的早侏罗世(200Ma)岩浆事件可以用西非克拉通下的一个大规模地幔柱(超级地幔柱)上升来解释。岩石圈下部地幔流向北东方向外流的侧向偏离能解释拉斑玄武岩岩浆作用从巴西到西班牙南部延伸近5000km。据认为,大陆裂解出现在停滞流线之上,沿停滞流线被地幔柱从大陆岩石圈底部侵蚀的冷物质返回对流地幔。动力模式是根据最近从夏威夷地幔柱模式提出的,该模式满意地解释了为什么中大西洋洋壳生成时没有热异常地幔。Marjorie Wilson 韩欣 1998地质科学译丛1998,15,2:3
11Pediatric Nd:YAG laser capsulotomy in the operating room: review of 87 cases显示文摘AIM: To report a large series of children having Nd:YAG laser capsulotomy in the operating room using the lateral decubitus position. METHODS: Medical records of children who underwent Nd:YAG laser capsulotomy in the operating room at Ann & Robert H. Lurie Children's Hospital of Chicago between September 2008 and April 2017 were reviewed. Induction of general anesthesia and intubation was performed in the supine position after which the patient was placed in lateral decubitus position. The Nd:YAG laser capsulotomy was performed using a standard protocol. At the completion of the procedure, the patient was turned back into the supine position and extubated. RESULTS: This study included 87 eyes of 60 patients. Patient's age ranged from 1 to 18 y(mean 6.4±4.1 y). In most cases(84/87, 97%), the procedure was performed under general anesthesia. In all cases, good focus on the membrane was achieved, and the procedure was performed successfully. There were no intraoperative ocular or anesthesia-related complications. CONCLUSION: When performing Nd:YAG laser capsulotomy in the operating room, the lateral decubitus position allowsan easy and safe approach without the risk of potentially devastating complications that have been associated with the previously described sitting and prone positions.Michael Kinori Narasimhan Jagannathan Anne M Langguth Marjorie A Sasso Marilyn B Mets Bahram Rahmani Hawke Yoon Rebecca Mets-Halgrimson Sudhi P Kurup Janice L Zeid 2019International Journal of Ophthalmology(English edition)2019,12,5:2
12Ecophysiological responses of two closely related Magnoliaceae genera to seasonal changes in subtropical China显示文摘Aims Plants use a variety of hydraulic strategies to adapt to seasonal drought that differ by species and environmental conditions.The early-diverging Magnoliaceae family includes two closely related genera with contrasting leaf habits,Yulania(deciduous)and Michelia(evergreen),which naturally inhabit temperate and tropi-cal regions,respectively.Here,we evaluate the hydraulic strategy of species from both genera that have been ex situ conserved in a subtropical region to determine how they respond to the novel cool-dry season climatic pattern.Methods We measured ecophysiological traits in five Michelia and five Yulania species conserved in the South China Botanical Garden in both wet and dry season conditions and monitored the whole-year sap flow for four of these species.Important Findings We found that Magnoliaceae species that have been ex situ con-served in a subtropical climate did not suffer from excessive water stress due to the mild drought conditions of the dry season and the ecophysiological adjustments the species made to avoid this stress,which differed by leaf habit.Specifically,deciduous species com-pletely shed their leaves during the dry season,while evergreen species decreased their turgor loss points,dry mass based photo-synthetic rates,stomatal conductance and specific leaf areas(SLAs)compared to wet season measurements.In comparing the two dis-tinct leaf habits during the wet season,the leathery-leaved evergreen species had higher leaf hydraulic conductance and leaf to sapwood area ratios than the papery-leaved deciduous species,while the deciduous species had greater hydraulic conductivity calculated on both a stem and leaf area basis,dry mass based photosynthetic rates,leaf nutrients,SLAs and stomatal sizes than the evergreen species.Interestingly,species from both genera maintained similar sap flow in the wet season.Both photosynthetically active radia-tion and vapour pressure deficit affected the diurnal patterns of sap flow in the wet season,while only vapour pressure deficit played a dominant role in the dry season.This study reveals contrasting hydraulic strategies in Yulania and Michelia species under subtropi-cal seasonal conditions,and suggests that these ecophysiological adjustments might be affected more by leaf habit than seasonality,thus reflecting the divergent evolution of the two closely related genera.Furthermore,we show that Magnoliaceae species that are ex situ conserved in a subtropical climate are hydraulically sound,a finding that will inform future conservation efforts of this ancient family under the threat of climatic change.Hui Liu Liwei Zhu Qiuyuan Xu Marjorie R.Lundgren Keming Yang Ping Zhao Qing Ye 2018Journal of Plant Ecology2018,11,3:2
13Predicting corporate financial distress: Reflections on choice-based sample bias显示文摘Harlan D. Platt Marjorie B. Platt Journal of Economics and Finance0,,:2
14High throughput genetic transformation mediated by Agrobacterium tumefaciens in maize显示文摘Zuo-yu Zhao Weining Gu Tishu Cai Laura Tagliani David Hondred Diane Bond Sheryl Schroeder Marjorie Rudert Dottie Pierce 2002Molecular Breeding2002,,4:2
15Ion Channels at the Nucleus: Electrophysiology Meets the Genome显示文摘原子信封被对在原子核影响基因抄写和另外的进程的信号 transduction 小径感兴趣的研究人员逐渐地从一个 electrophysiological 观点看。这里,我们由原子毛孔在原子膜并且为可能的离子 gating 为离子隧道和 transporters 描述证据。我们主张细胞的规定的系统级的理解是可能的要求原子 electrophysiology 的吸收进分子、生物化学的发信号的小径。Antonius J.M. Matzkea Thomas M. Weiger Marjori Matzke 2010Molecular Plant2010,3,4:2
16RNA-mediated chromatin-based silencing in plants显示文摘Marjori Matzke Tatsuo Kanno Lucia Daxinger Bruno Huettel Antonius JM Matzke 2009Current Opinion in Cell Biology2009,,3:2
17Human immunodeficiency virus type-1 induces a regulatory B cell-like phenotype in vitro显示文摘Individuals infected with human immunodeficiency virus type-1(HIV-1)usually show a general dysregulation and hyper-activation of the immune system.A direct influence of HIV-1 particles on B-cell phenotypes and functions has been previously described.However,the consequences of B-cell dysregulation are still poorly understood.We evaluated the phenotypic changes in primary B cells after direct contact with HIV-1 particles in comparison with different types of stimuli.The functionality of treated B cells was challenged in co-culture experiments with autologous CD4+and CD8+T cells.We demonstrated that HIV-1 induces a phenotypic change in B cells towards a regulatory B-cell phenotype,showing a higher level of IL-10,TGF-β1,EBI3 or IL-12(p35)mRNA expression and acquiring an immunosuppressive profile.The acquisition of a Breg phenotype was confirmed by co-culture experiments where HIVtreated B cells reduced the proliferation and the TNFαproduction of CD4+or CD8+T cells.This suppressive ability of HIV-treated B cells was dependent on cell-to-cell contact between these B cells and effector cells.To our knowledge,these data provide the first evidence that HIV-1 can directly induce a regulatory B cell-like immunosuppressive phenotype,which could have the ability to impair specific immune responses.This dysregulation could constitute one of the mechanisms underlying unsuccessful efforts to develop an efficient vaccine against HIV-1.Jacobo Lopez-Abente Adrián Prieto-Sanchez Maria-Ángeles Muñoz-Fernandez Rafael Correa-Rocha Marjorie Pion 2018Cellular & Molecular Immunology2018,15,10:2
18Absorptive capacity, learning, and performance in international joint ventures显示文摘Peter J.Lane Jane E.Salk Marjorie A.Lyles 2001Strat. Mgmt. J2001,,12:2
19Inter- and intra-organizational knowledge transfer: a meta-ana- lytic review and assessment of its antecedents and eonse- quences显示文摘RAYMOND W JUSTIN J P J MARJORIE A L 2008Journal of Management Studies2008,45,4:1
20Developmental Changes in the Consideration of Sample Diversity in Inductive Reasoning显示文摘Marjorie Rhodes Susan A. Gelman Daniel Brickman 2008Journal of Cognition and Development2008,,1:1
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