|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Outcome anal- ysis of treatment of nephroblastoma in children older than 5 years and adults显示文摘 | Dmilriy AR Vsevolod BM Maria IV | 2008 | J Uroi2008，179，41： | 1 |
| 2 | Serum levels of chemokines in adolescents with major depression treated with fluoxetine显示文摘BACKGROUND Major depressive disorder(MDD)is a global health issue that affects 350 million people of all ages.Although between 2%and 5.6%of affected individuals are adolescents,research on young patients is limited.The inflammatory response contributes to the onset of depression,and in adult MDD patients,symptom severity has been linked to chemokine levels.AIM To determine the differences in circulatory levels of chemokines in healthy volunteers(HVs)and adolescents with MDD,and assess the changes induced by fluoxetine consume.METHODS The 22 adolescents with MDD were monitored during the first 8 wk of clinical follow-up and clinical psychiatric evaluation was done using the Hamilton depresión rating scale(HDRS).The serum levels of monocyte chemoattractant protein-1(MCP-1),macrophage inflammatory protein(MIP)-1α,MIP-1β,interleukin(IL)-8,interferon gamma-induced protein(IP)-10,and eotaxin were measured in patients and HVs.RESULTS In all cases,significant differences were detected in circulating chemokine levels between patients before treatment and HVs(P<0.0001).All chemokines decreased at 4 wk,but only MCP-1 and IL-8 significantly differed(P<0.05)between 0 wk and 4 wk.In the patients,all chemokines rose to their initial concentrations by 8 wk vs 0 wk,but only IP-10 did so significantly(P<0.05).All patients experienced a significant decrease in HDRS scores at 4 wk(P<0.0001)and 8 wk(P<0.0001)compared with 0 wk.CONCLUSION Despite the consumption of fluoxetine,patients had significantly higher chemokine levels,even after considering the improvement in HDRS score.The high levels of eotaxin,IP-10,and IL-8 partially explain certain aspects that are affected in MDD such as cognition,memory,and learning. | Francisco Rafael de la Peña Carlos Cruz-Fuentes Lino Palacios Manuel Iván Girón-Pérez Emilio Medina-Rivero Maria Dolores Ponce-Regalado Samantha Alvarez-Herrera Gilberto Pérez-Sánchez Enrique Becerril-Villanueva JoséLuis Maldonado-García María C Jiménez-Martínez Lenin Pavón | 2020 | World Journal of Psychiatry2020，10，8： | 1 |
| 3 | Measuring the relationship of quality of life and health status,includin: tumor hurden,symptoms,and bio- chemical measures in patients with neuroendocrine tumors 显示文摘 | Etta V Maria PS Aaron IV | 2011 | En- docrinology and Metabolism Clinics of North America2011，40，1： | 1 |
| 4 | Co-occurrence of aflatoxins,ochratoxin A and zearalenone in barley from a northern region of Spain显示文摘 | Maria IV Elena GP Elena L | | 0，，01： | 1 |
| 5 | Functional vascular endothelial growth factor -634G>C SNP is associated with proliferative diabetic retinopathy:A case-control study in a Brazilian population of European ancestry显示文摘 | Flavia IV Luís HC Maria ER | 2007 | Diabetes Care2007，30，2： | 1 |
| 6 | Glial cells in the center of future ischemic stroke treatments显示文摘In the last century,increasing knowledge about glial cells has revealed their importance in brain physiology and disease and an exciting potential target for new therapeutic interventions(Hernández et al.,2021).Ischemic stroke is the most common of all types of stroke.As the second leading cause of disability and mortality,ischemic stroke is a serious socio-economic burden worldwide.Although it has been strongly associated with aging,during 2020 COVID-19 emerged as a new risk factor for ischemic stroke in younger patients(Cagnazzo et al.,2021).The only therapy or intervention currently available for humans is early reperfusion after the onset of the first symptoms.However,due to the high risk of brain hemorrhage,these treatments are suitable for only a small percentage of patients.Moreover,reperfusion does not prevent post-injury neurodegeneration,hence the importance of finding new therapeutic alternatives to ameliorate ischemic damage and improve post-stroke quality of life. | IvóH.Hernández Maria JoséPérez-Álvarez | 2022 | Neural Regeneration Research2022，17，12： | 1 |
| 7 | Ergatoid reproductives in the Neotropical termite Nasutitermes aquilinus (Holmgren) (Blattaria: Isoptera: Termitidae): developmental origin, fecundity, and genetics显示文摘Termite colonies are usully headed by primary reproductives,which estab-listh nests during the swar ming scason.However,secondary reproductives may develop in some specics and become supplementary or replacement breeders,extending colony lifes-pan.Here we investigate the developmental origin,fecundity and genetic characterizaion of ergatoid reproductives in the Neotropical termite Nasuitermes aquilinus(Holmgren),using morphometrical and histological techniques,five micosiallitle loci and the COI mitochondrial DNA.Twelve measurements performed on 208 apterous individuals of Nuauidius revealed 10 groups,including ergatoid females,which developed from major workers through two successive molts.and were characterized by the presence of imaginal features such as eyes andl wing buds.The difentiation of these features was correlated to physogastric development in these ergatoids,Histology revealed ooeytes in all matu-ration sages in worker-derived reproductives of N aquidinus,presence of nonflagellate spermatozoa inside the spermatheea,and royal fa body.Thus,ergatoid reproduwetives were reproductively functional.According to the genotypes of 221 individuals from 11 nests,and mitochondrial haplotypes of 43 ergatoids,73%of the colomies were simple families,whereas 27%were extendbed families.Despite the oecurenee of related reproductives,low inbreeding rates were detected within and among colonies.Such values could be explained given that sib mating itself cannot result in a higher inbreeding rate but depend on several factors discussed in detail.This is the first study to investigate the genetic structure of termite colonies influenced by the development of ergatoids and further investigations are encouraged 10 understand the inflwence of these reproductives on colony lifespan. | Iago Bueno da Silva Ives Haifig Edward LVargo Fabiana Elaine Casarin Marcelo Luiz da Mota Juliana Toledo Lima Ana Maria Costa-Leonardo | 2020 | Insect Science2020，27，6： | 0 |
| 8 | Observatory science with eXTP显示文摘In this White Paper we present the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to Observatory Science targets. These include flaring stars, supernova remnants, accreting white dwarfs, low and high mass X-ray binaries, radio quiet and radio loud active galactic nuclei, tidal disruption events, and gamma-ray bursts. eXTP will be excellently suited to study one common aspect of these objects: their often transient nature. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Science, the eXTP mission is expected to be launched in the mid 2020s. | Jean J.M.in 't Zand Enrico Bozzo JinLu Qu Xiang-Dong Li Lorenzo Amati Yang Chen Immacolata Donnarumma Victor Doroshenko Stephen A.Drake Margarita Hernanz Peter A.Jenke Thomas J.Maccarone Simin Mahmoodifar Domitilla de Martino Alessandra De Rosa Elena M.Rossi Antonia Rowlinson Gloria Sala Giulia Stratta Thomas M.Tauris Joern Wilms XueFeng Wu Ping Zhou Iván Agudo Diego Altamirano Jean-Luc Atteia Nils A.andersson M.Cristina Baglio David R.Ballantyne Altan Baykal Ehud Behar Tomaso Belloni Sudip Bhattacharyya Stefano Bianchi Anna Bilous Pere Blay Joao Braga Sφren Brandt Edward F.Brown Niccolo Bucciantini Luciano Burderi Edward M.Cackett Riccardo Campana Sergio Campana Piergiorgio Casella Yuri Cavecchi Frank Chambers Liang Chen Yu-Peng Chen Jér?me Chenevez Maria Chernyakova ChiChuan Jin Riccardo Ciolfi Elisa Costantini Andrew Cumming Antonino D'Aì Zi-Gao Dai Filippo D'Ammando Massimiliano De Pasquale Nathalie Degenaar Melania Del Santo Valerio D'Elia Tiziana Di Salvo Gerry Doyle Maurizio Falanga XiLong Fan Robert D.Ferdman Marco Feroci Federico Fraschetti Duncan K.Galloway Angelo F.Gambino Poshak Gandhi MingYu Ge Bruce Gendre Ramandeep Gill Diego G?tz Christian Gouiffès Paola Grandi Jonathan Granot Manuel Güdel Alexander Heger Craig O.Heinke Jeroen Homan Rosario Iaria Kazushi Iwasawa Luca Izzo Long Ji Peter G.Jonker Jordi José Jelle S.Kaastra Emrah Kalemci Oleg Kargaltsev Nobuyuki Kawai Laurens Keek Stefanie Komossa Ingo Kreykenbohm Lucien Kuiper Devaky Kunneriath Gang Li En-Wei Liang Manuel Linares Francesco Longo FangJun Lu Alexander A.Lutovinov Denys Malyshev Julien Malzac Antonios Manousakis Ian McHardy Missagh Mehdipour YunPeng Men Mariano Méndez Roberto P.Mignani Romana Mikusincova M.Coleman Miller Giovanni Miniutti Christian Motch Joonas Nättilä Emanuele Nardini Torsten Neubert Paul T.O'Brien Mauro Orlandini Julian P.Osborne Luigi Pacciani Stéphane Paltani Maurizio Paolillo Iossif E.Papadakis Biswajit Paul Alberto Pellizzoni Uria Peretz Miguel A.Pérez Torres Emanuele Perinati Chanda Prescod-Weinstein Pablo Reig Alessandro Riggio Jerome Rodriguez Pablo Rodríguez-Gil Patrizia Romano Agata Rózańska Takanori Sakamoto Tuomo Salmi Ruben Salvaterra andrea Sanna andrea Santangelo Tuomas Savolainen Stéphane Schanne Hendrik Schatz LiJing Shao andy Shearer Steven N.Shore Ben W.Stappers Tod E.Strohmayer Valery F.Suleimanov Jirí Svoboda F.-K.Thielemann Francesco Tombesi Diego F.Torres Eleonora Torresi Sara Turriziani andrea Vacchi Stefano Vercellone Jacco Vink Jian-Min Wang JunFeng Wang Anna L.Watts ShanShan Weng Nevin N.Weinberg Peter J.Wheatley Rudy Wijnands Tyrone E.Woods Stan E.Woosley ShaoLin Xiong YuPeng Xu Zhen Yan George Younes WenFei Yu Feng Yuan Luca Zampieri Silvia Zane andrzej A.Zdziarski Shuang-Nan Zhang Shu Zhang Shuo Zhang Xiao Zhang Michael Zingale | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 0 |
| 9 | Meiotic behavior and pollinic viability in bean cultivars显示文摘The aims of this study were to determine the meiotic behavior and to estimate pollen grains via-bility in bean(Phaseolus vulgaris L.)cultivars.Flower buds were collected during different developmental stages of the Mesoamerican bean cultivars IAPAR 44,Guapo Brilhante,BRS Expedito,BRS Valente,Guateian 6662 and Pérola,and the Andean bean cultivar Iraí,grown in a greenhouse.The meiotic index was determined by anther squashing of material fixed in absolute ethanol-glacial acetic acid(3:1)and stained with acetic orcein.No meiotic abnormalities were observed and the meiotic indices were high for all cultivars,indicating that the mismatch generated during crosses is not related to any meiotic changes.Estimation of pollen viability was made by comparing acetic orcein staining vs.Alexander’s reactive:pollen viability was high in all cultivars with either stain,but was significantly higher when using the acetic orcein stain(>99%).Though some cultivar showed a significantly smaller pollen size,the range of variation among cultivars was low(means’range 51-66μm). | Gracieli DALLA NORA Solange Bosio TEDESCO Tamara PASTORI Viviane Dal-Souto FRESCURA Nerinéia Dalfollo RIBEIRO Haywood Dail LAUGHINGHOUSE IV Sidinei JoséLOPES Maria Teresa SCHIFINO-WITTMANN | 2014 | BIOCELL2014，38，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员