| 4 | Quinine induced thrombotic microangiopathy and thrombocytopenia: A teaching hospital’s perspective显示文摘Although quinine is an infrequently prescribed drug, with malaria treatment being its only FDA-approved indication, unwitting exposure via beverages (e.g., tonic water), over the counter herbal remedies and illegal recreation drugs still occur. We present a unique case of a female patient who denied any known prior history of quinine exposure, who after being prescribed quinine tablets for restless leg syndrome, developed an immune-related thrombotic microangiopathy with thrombocytopenia and subsequent multi-organ failure. It was later elucidated that her only known potential source of prior quinine exposure was a remote history of crackcocaine use. The patient survived this rare and severe inflammatory response with recovery of renal function and was able to discontinue dialysis. | Aaron J. Franke William Paul Skelton IV | 2019 | Advances in Generial Practice of Medicine2019，2，1： | 0 |
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