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| 1 | Transcranial direct current stimulation in psychiatric disorders显示文摘The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry. | Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni | 2015 | World Journal of Psychiatry2015，5，1： | 6 |
| 2 | The capsanthin-capsorubin synthase gene: a candidate gene for the y locus controlling the red fruit colour in pepper显示文摘 | Véronique Lefebvre Marcel Kuntz Bilal Camara Alain Palloix | 1998 | Plant Molecular Biology1998，，5： | 2 |
| 3 | Understanding wild-type and mutant p53 activities in human cancer:new landmarks on the way to targeted therapies显示文摘 | Goldstein I Marcel V Olivier M | 2011 | Cancer Gene Ther2011，18，1： | 1 |
| 4 | Watersnakes: energy driven watershed segmentation 显示文摘 | HIEU T MARCEL M REIN V | 2003 | IEEE Transaction on Pattern Analy- sis and Machine Intelligence2003，25，3： | 1 |
| 5 | Watersnakes: Energy-driven watershed segmentation 显示文摘 | HIEU T MARCEL M REIN V | 2003 | IEEE Transaction on Pattern Analysis and Machine Intelligence2003，25，3： | 1 |
| 6 | Conformational effects in crow ether complexation of lithium picrota in solvents of low polarity显示文摘 | MARCEL V B JOHANNES S | 1994 | J Phys Chern1994，98，17： | 1 |
| 7 | Watersnakes:energy-driven watershed segmentation显示文摘 | HIEU T MARCEL M REIN V | 2003 | IEEE Trans on Pattern Analysis and Machine Intelligence2003，25，3： | 1 |
| 8 | Understanding wild- type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies显示文摘 | Goldstein I Marcel V Olivier M | 2011 | Cancer Gene Therapy2011，18，1： | 1 |
| 9 | Exploration of the Drosophila acetylcholinesterase substrate activation site using a reversible inhibitor (Triton X-100) and mutated enzymes 显示文摘 | Marcel V Estrada-Mondaca S Magné F | 2000 | J Biol Chem2000，275，： | 1 |
| 10 | Adjustment to climate change is constrained by arrival date in a long distance migrant bird 显示文摘 | Christiaan B Marcel E V | 2001 | Nature2001，411，6835： | 1 |
| 11 | Phage therapy reduces Campylobacterjejuni colonization in broilers显示文摘 | JAAP A W MARCEL A P V B MARK A M | 2005 | Veterinary Microbilogy2005，109，： | 1 |
| 12 | Evolution of compressive strains in retained austenite during sub-zero Celsius martensite formation and tempering 显示文摘 | Matteo V Karen P Marcel A J S | 2014 | Acta Materialia2014，65，： | 1 |
| 13 | Hepatic adenoma and focal nodular hy- perplasia:differential diagnosis and treatment 显示文摘 | Hennan P Puglies V Marcel AC | 2000 | World J Smg2000，24，3： | 1 |
| 14 | Heat shock proteins and amateur chaperones in amyloid-beta accumulation and clearance in Alzheimer' s disease 显示文摘 | Micha M M W Robert M W W Marcel M V | 2007 | Mol Neurobiol2007，35，： | 1 |
| 15 | The many functions of ERECTA 显示文摘 | ZANTEN M V BASTEN L S MARCEL C G | 2009 | Trends in Plant Science2009，14，4： | 1 |
| 16 | Short mucin 6 alleles are associated with H pylori infection显示文摘AIM: To investigate the relationship between mucin 6 (MUC6) VNTR length and H pylori infection. METHODS: Blood samples were collected from patients visiting the Can Tho General Hospital for upper gastrointestinal endoscopy. DNA was isolated from whole blood, the repeated section was cut out using a restriction enzyme (PvuⅡ) and the length of the allelefragments was determined by Southern blotting. H pylori infection was diagnosed by 14C urea breath test. For analysis, MUC6 allele fragment length was dichotomized as being either long (> 13.5 kbp) or short (≤ 13.5 kbp) and patients were classif ied according to genotype [long- long (LL), long-short (LS), short-short (SS)].RESULTS: 160 patients were studied (mean age 43 years, 36% were males, 58% H pylori positive). MUC6 PvuⅡ-restricted allele fragment lengths ranged from7 to 19 kbp. Of the patients with the LL, LS, SS MUC6 genotype, 43% (24/56), 57% (25/58) and 76% (11/46) were infected with H pylori, respectively (P = 0.003).CONCLUSION: Short MUC6 alleles are associated with H pylori infection. | Thai V Nguyen Marcel JR Janssen Paulien Gritters René HM te Morsche Joost PH Drenth Henri van Asten Robert JF Laheij Jan BMJ Jansen | 2006 | World Journal of Gastroenterology2006，12，37： | 1 |
| 17 | Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies 显示文摘 | Goldstein I Marcel V Olivier M | 2011 | Cancer Gene Ther2011，18，1： | 1 |
| 18 | The role of interfacial rheological properties on OstwaId ripening in emulsions 显示文摘 | MARCEL B J M TONVAN V | 2004 | Advances in Colloid and Interface Science2004，，： | 1 |
| 19 | Twin pregnancy with complete hydatidiform mole and coexistent fetus显示文摘 | Jér?me Massardier Fran?ois Golfier Dorothée Journet Lucien Frappart Marcel Zalaquett Anne Marie Schott Véronique Trillet Lenoir Olivier Dupuis Touria Hajri Daniel Raudrant | 2009 | European Journal of Obstetrics and Gynecology2009，，2： | 1 |
| 20 | Stabilization of caveolin-1 by cellular cholesterol and scavenger receptor class B type I显示文摘 | Frank PG Marcel YL Connelly MA Lublin DM Franklin V Williams DL | 2002 | Biochemistry2002，41，11： | 1 |
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