|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity显示文摘 | Corbin Amie S Agarwal Anupriya Loriaux Marc Cortes Jorge Deininger Michael W Druker Brian J | 2011 | Journal of Clinical Investigation2011，，1： | 3 |
| 2 | Bovine immunoglobulin protein isolates for the nutritional management of enteropathy显示文摘The gastrointestinal tract is responsible for a multitude of digestive and immune functions which depend upon the balanced interaction of the intestinal microbiota, diet, gut barrier function, and mucosal immune response. Disruptions in one or more of these factors can lead to intestinal disorders or enteropathies which are characterized by intestinal inflammation, increased gut permeability, and reduced capacity to absorb nutrients. Enteropathy is frequently associated with human immunodeficiency virus(HIV) infection, inflammatory bowel disease, autoimmune enteropathy, radiation enteritis, and irritable bowel syndrome(IBS), where pathologic changes in the intestinal tract lead to abdominal discomfort, bloating, abnormal bowel function(e.g., diarrhea, urgency, constipation and malabsorption). Unfortunately, effective therapies for the management ofenteropathy and restoring intestinal health are still not available. An accumulating body of preclinical studies has demonstrated that oral administration of plasmaor serum-derived protein concentrates containing high levels of immunoglobulins can improve weight, normalize gut barrier function, and reduce the severity of enteropathy in animal models. Recent studies in humans, using serum-derived bovine immunoglobulin/protein isolate, demonstrate that such protein preparations are safe and improve symptoms, nutritional status, and various biomarkers associated with enteropathy. Benefits have been shown in patients with HIV infection or diarrhea-predominant IBS. This review summarizes preclinical and clinical studies with plasma/serum protein concentrates and describes the effects on host nutrition, intestinal function, and markers of intestinal inflammation. It supports the concept that immunoglobulin-containing protein preparations may offer a new strategy for restoring functional homeostasis in the intestinal tract of patients with enteropathy. | Bryon W Petschow Anthony T Blikslager Eric M Weaver Joy M Campbell Javier Polo Audrey L Shaw Bruce P Burnett Gerald L Klein J Marc Rhoads | 2014 | World Journal of Gastroenterology2014，20，33： | 2 |
| 3 | 学历与一生的收入:德国最新的有关调查统计(上)显示文摘教育是一项耗费时间、精力和财力的投资。如果考虑劳动力市场以后给与的回报,这种投资是否值得?我们运用标准的净现值法,以德国当前的居民年龄与收入状况为基础,利用2011—2013年德国微观人口普查中超过100万人的数据,对不同受教育程度人群进行分类并计算他们之间终生收入的差异。研究结果表明,在整个职业生涯中,每一个较高的学历都会带来多出22%到64%的收入。但是,地域、性别,特别是职业培训和大学教育的不同专业也是影响收入差距的重要因素,例如医学和社会工作之间的差异就很大。 | Marc Piopiunik Franziska Kugler Ludger Wβmann 陈颖 | 2017 | 应用型高等教育研究2017，2，4： | 2 |
| 4 | Ultrasound of the ankle 显示文摘 | Cerard M Jacqoe B Marc W | 2001 | Eur J Ultr2001，14，1： | 1 |
| 5 | Localization of neuroglobin protein in the mouse brain显示文摘 | Sylvia W Tilmann L Marc S | 2003 | Neuroscience Letters2003，，1： | 1 |
| 6 | Rofecoxib, a COX-2 inhibitor,lowers C-reactive protein and interleukinq-6 levels in patients with acute coronary syndromes 显示文摘 | Monakier D Mates M Marc W | 2004 | Chest2004，125，： | 1 |
| 7 | Cell compartmentalization in planctomycetes:novel types of structural organization for the bacterial cell 显示文摘 | Margaret R L Richard I W Marc S | 2001 | Arch Microbiol2001，175，： | 1 |
| 8 | High Power Vacuum Window in WR10显示文摘 | MARC E H RICHARD S C DAVID H W | | 0，，05： | 1 |
| 9 | Ef- fects of aerobic and anaerobic conditions on P, N, Fe, Mn, and Hg accumulation in waters overlaying profundal sediments of an oligo-mesotrophic lake显示文摘 | Beutel Marc W Leonard Theo M Dent Stephen R | 2008 | Water Research2008，42，： | 1 |
| 10 | Breast cancer detection by Fourier transform infrared spectrometry 显示文摘 | Marc M Joellen W Jiashu T | 1996 | Vibrational Spectroscopy1996，10，： | 1 |
| 11 | Long_ term fol-low-up of meningiomas of the cavernous sinus after sur-gical treatment along 显示文摘 | Marc S Ernesto W Emmanuel J | 2007 | J Neurosurg2007，107，： | 1 |
| 12 | Evaluation of automated biometrics-based identification and verification systems 显示文摘 | Shen W Marc S Rajiv K | 1997 | Proceedings of IEEE1997，85，9： | 1 |
| 13 | Gastrointestinal tract access for urological natural orifice transluminal endoscopic surgery显示文摘We conducted a literature review of natural orifice transluminal endoscopic surgery(NOTES),focusing on urologic procedures with gastrointestinal tract access,to update on the development of this novel surgical approach.As part of the methods,a comprehensive electronic literature search for NOTES was conducted using Pub Med and Cochrane Library from March 2002 to February 2016 for papers reporting urologic procedures performed utilizing gastrointestinal tract access.A total of 11 peer-reviewed studies examining utility of gastrointestinal access for NOTES urologic procedures were noted,with the first report in 2007.The procedures reported in the studies were total/radical nephrectomy,partial nephrectomy,adrenalectomy,and prostatectomy.The transgastric approach was identified in five studies examining total/radical nephrectomy(n = 2),partial nephrectomy(n = 1),partial cystectomy(n = 1),and adrenalectomy(n = 1).Six studies evaluated transrectal approach for NOTES,describing total/radical nephrectomy(n = 3),partial nephrectomy(n = 1),robotic nephrectomy with adrenalectomy(n = 1) and prostatectomy(n = 1).Feasibility was reported in all studies.Most studies were preclinical and acute,and limited by concerns regarding restricted instrumentation and infection risk.We concluded that gastrointestinal access for urologic NOTES demonstrates promise as described by outlined feasibility studies in preclinical models.Nonetheless,clinical application awaits further advancements in surgical technology and concerns regarding infectious potential. | Olga Miakicheva Zachary Hamilton Alp T Beksac Sean W Berquist Abd-elrahman Hassan Marc Holden Ithaar H Derweesh | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，19： | 1 |
| 14 | Content-based image retrieval at the end of the early years显示文摘 | MARCE W SIMONE S | 2000 | IEEE Transactions on Pattern Analysis and Machine Intelligence2000，22，12： | 1 |
| 15 | High Power Vacu um Window in WR10 显示文摘 | Marc EH Richard S C David H W | 2001 | IEEE Transactions on Micro wave Theory and Technique2001，49，5： | 1 |
| 16 | Ultrasound of the ankle显示文摘 | CERARDMO R JACQUE B MARC W Y | 2001 | European Journal of Ultrasound2001，14，1： | 1 |
| 17 | Effects of aerobic and anaerobic conditions on P, N, Fe, bin, andhgaccumulation in waters overlaying profundal sediments of an oligo-mesotrophic lake 显示文摘 | MARC W B THEO M L STEPHEN R D | 2008 | Water Res2008，42，： | 1 |
| 18 | Novel electrode materials for thin-film ultracapacitors:comparison of electrochemical properties of Sol-Gel-derived and electrodeposited manganese dioxide显示文摘 | Suh-Cem Pang Marc A Anderson Thomas W Chapman | 2000 | J Electrochem Soc2000，147，： | 1 |
| 19 | The impact of patient and tumour baseline characteristics on the overall survival of patients with advanced hepatocellular carcinoma treated with sorafenib显示文摘 | Marcus A. W?rns Sandra Koch Ina M. Niederle Jens U. Marquardt Marc Nguyen-Tat Thomas Gamst?tter Marcus Schuchmann Henning Schulze-Bergkamen Peter R. Galle Arndt Weinmann | 2012 | Digestive and Liver Disease2012，，： | 1 |
| 20 | Dosimetry systems for radiation processing显示文摘 | Mclaughlin W L Marc F | 1995 | Radiation Phys Chem1995，46，46： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员