|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | High levels of serum interleukin-6 increase mortality of hepatitis B virus-associated acute-on-chronic liver failure显示文摘BACKGROUND Patients with hepatitis B virus-associated acute-on-chronic liver failure(HBVACLF)present a complex and poor prognosis.Systemic inflammation plays an important role in its pathogenesis,and interleukin-6(IL-6)as a pro-inflammatory cytokine is related with severe liver impairment and also plays a role in promoting liver regeneration.Whether serum IL-6 influences HBV-ACLF prognosis has not been studied.AIM To determine the impact of serum IL-6 on outcome of patients with HBV-ACLF.METHODS We performed a retrospective study of 412 HBV-ACLF patients.The findings were analyzed with regard to mortality and the serum IL-6 level at baseline,as well as dynamic changes of serum IL-6 within 4 wk.RESULTS The serum IL-6 level was associated with mortality.Within 4 wk,deceased patients had significantly higher levels of IL-6 at baseline than surviving patients[17.9(7.3-57.6)vs 10.4(4.7-22.3),P=0.011].Patients with high IL-6 levels(>11.8 pg/mL)had a higher mortality within 4 wk than those with low IL-6 levels(≤11.8 pg/mL)(24.2%vs 13.2%,P=0.004).The odds ratios calculated using univariate and multivariate logistic regression were 2.10(95%confidence interval[CI]:1.26-3.51,P=0.005)and 2.11(95%CI:1.15-3.90,P=0.017),respectively.The mortality between weeks 5 and 8 in patients with high IL-6 levels at 4 wk was 15.0%,which was significantly higher than the 6.6%mortality rate in patients with low IL-6 levels at 4 wk(hazard ratio=2.39,95%CI:1.05-5.41,P=0.037).The mortality was 5.0%in patients with high IL-6 levels at baseline and low IL-6 levels at 4 wk,7.5%in patients with low IL-6 levels both at baseline and at 4 wk,11.5%in patients with low IL-6 levels at baseline and high IL-6 levels at 4 wk,and 16.7%in patients with high IL-6 levels both at baseline and at 4 wk.The increasing trend of the mortality rate with the dynamic changes of IL-6 was significant(P for trend=0.023).CONCLUSION A high level of serum IL-6 is an independent risk factor for mortality in patients with HBV-ACLF.Furthermore,a sustained high level or dynamic elevated level of serum IL-6 indicates a higher mortality. | Chao Zhou Ning Zhang Ting-Ting He Yao Wang Li-Fu Wang Yong-Qiang Sun Jing Jing Jing-Jing Zhang Shuang-Nan Fu Xuan Wang Xiao-Xiao Liang Xin Li Man Gong Jun Li | 2020 | World Journal of Gastroenterology2020，26，30： | 15 |
| 2 | Evaluation of a simulation-based workshop on clinical performance for emergency physicians and nurses显示文摘BACKGROUND: Simulation-based medical education has been growing rapidly and becomes one of the most popular teaching methods for improving patient safety and patient care. The Simulation Subcommittee of the Hong Kong College of Emergency Medicine organized an educational program emphasizing the team training, clinical decision-making and communication skills. This study aimed to evaluate the attitude of the participants toward a new training program and the change in the knowledge on clinical performance in emergency physicians and nurses after attending the educational program.METHODS: A course evaluation form was filled in by the participants at the end of the workshop. An assessment of 20 multiple-choice questions with 5 options was administered to the participants before and after the 2-day simulation-based training workshop.RESULTS: A total of 72 doctors and nurses working in the Accident and Emergency Department were enrolled. The average pretest and posttest scores were 12 and 14.3 respectively. The percentage improvement in the mean score of the pretest and posttest was 11.5%. The Chi-square test showed signifi cant improvement in the pretest and posttest score grading(P=0.00). Paired t-test revealed signifi cant difference between the mean scores of the pretest and posttest(P=0.00).CONCLUSIONS: Participants had positive attitude toward this new training program. Significant improvement of the knowledge on clinical performance in healthcare professionals in the Accident and Emergency Department was observed after the participation in this simulation-based educational program. | Chi Ho Chan Tung Ning Chan Man Cheuk Yuen Wai Kit Tung | 2015 | World Journal of Emergency Medicine2015，6，1： | 14 |
| 3 | Mechanisms of organized atrial tachycardia during catheter ablation of chronic atrial fibrillation by stepwise approach显示文摘背景广泛的 atrial 纤维性颤动(AF ) 脱离在长期的 AF 病人和 atrial 心悸亢进的增加的率与导管脱离的增加的成功率被联系(在) 在过程期间。这些 Ats 的机制在以前的研究变化。我们的学习试图报导机制在发生在逐步的脱离期间组织了长期的 AF.Methods 的过程为长期的 atrial 纤维性颤动(CAF ) 经历了一个脱离过程的 86 个连续病人的一个未来的队被调查。逐步的过程在下列顺序被执行:环绕的肺的静脉脱离,复杂 fractionated atrial 电记录图脱离,印射并且脱离在。在湾穴节奏(SR ) 被恢复或过程时间在 6 hours.Results 以外以后,端点是 AF/AT 的 noninducibility (80%) 69 病人变换成 SR 经由在。179 持续 ATs 的一个总数在过程期间在 69 个病人被观察。有 81%(n=145 ) 包括了 65 个 perimitral 电路, 48 peritricuspid 心悸亢进和 32 个房顶依赖者电路的 macroreentrant ATs, 12%(n=21 ) 局部性重入并且 7%(n=13 ) 焦点的 ATs。三十(15%) 病人们在过程经历了重要左中庭(LA ) 和 LA 附器(LAA ) 传导延期或分离或在后续 period.Conclusions 期间,大多数 CAF 病人经由脱离变换成 SR 在发生在逐步的过程期间组织了。大多数这些 ATs 的机制是宏再废。 | NING Man DONG Jian-zeng LIU Xing-peng YU Rong-hui LONG De-yong TANG Ri-bo SANG Cai-hua MA Chang-sheng | 2010 | Chinese Medical Journal2010，，7： | 10 |
| 4 | Diluted ferromagnetic semiconductor(LaCa)(ZnMn)SbO isostructural to “1111” type iron pnictide superconductors显示文摘We report discovery of ferromagnetism in(LaCa)(ZnMn)SbO isostructural to the well-studied iron-based superconductor LaFeAs(O1 xFx).Spin is induced by partial substitution of Mn2+for Zn2+,while charge is induced by substitution of Ca2+for La3+within the parent compound LaZnSbO.Ferromagnetism with Curie temperature(TC)is observed up to 40 K at the spin doping 0.15 by introducing Mn2+into the Zn2+sites for(La0.95Ca0.05)(Zn1 xMnx)SbO.The Hall coefficient measurement indicates p-type carrier for(La0.95Ca0.05)(Zn0.9Mn0.1)SbO with concentration of n^1020cm 3showing anomalous Hall effect below TC. | HAN Wei ZHAO Kan WANG XianCheng LIU QingQing NING FanLong DENG Zheng LIU Ying ZHU JinLong DING Cui MAN HuiYuan JIN ChangQing | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，11： | 8 |
| 5 | MicroRNA396-mediated alteration in plant development and salinity stress response in creeping bentgrass显示文摘The conserved microRNA396(miR396)is involved in plant growth,development,and abiotic stress response in multiple plant species through regulating its targets,Growth Regulating Factor(GRF)transcription factor genes.However,the role of miR396 has not yet been characterized in perennial monocot species.In addition,the molecular mechanism of miR396-mediated abiotic stress response remains unclear.To elucidate the role of miR396 in perennial monocot species,we generated transgenic creeping bentgrass(Agrostis stolonifera)overexpressing Osa-miR396c,a rice miRNA396 gene.Transgenic plants exhibited altered development,including less shoot and root biomass,shorter internodes,smaller leaf area,fewer leaf veins,and epidermis cells per unit area than those of WT controls.In addition,transgenics showed enhanced salt tolerance associated with improved water retention,increased chlorophyll content,cell membrane integrity,and Na^(+)exclusion during high salinity exposure.Four potential targets of miR396 were identified in creeping bentgrass and up-regulated in response to salt stress.RNA-seq analysis indicates that miR396-mediated salt stress tolerance requires the coordination of stress-related functional proteins(antioxidant enzymes and Na+/H+antiporter)and regulatory proteins(transcription factors and protein kinases).This study establishes a miR396-associated molecular pathway to connect the upstream regulatory and downstream functional elements,and provides insight into the miRNA-mediated regulatory networks. | Shuangrong Yuan Junming Zhao Zhigang Li Qian Hu Ning Yuan Man Zhou Xiaoxia Xia Rooksie Noorai Christopher Saski Shigui Li Hong Luo | 2019 | Horticulture Research2019，6，1： | 8 |
| 6 | Laparoscopic Retrieval of a Tilted Inferior Vena Cava Filter显示文摘 | Hai-Dong Wang Jian-Long Liu Wei Jia Peng Jiang Ning Zhou Zhen-Hua Liu Li-Bo Man | 2018 | Chinese Medical Journal2018，，7： | 8 |
| 7 | Long-term postoperative outcomes of bilateral lateral rectus recession vs unilateral recession-resection for intermittent exotropia显示文摘AIM: To discuss the long-term postoperative results of bilateral lateral rectus recession(BLR) and unilateral lateral rectus recession-medial rectus resection(RR) in therapy of intermittent exotropia.METHODS: We retrospectively analyzed 213 cases of intermittent exotropia who underwent surgery between2008 and 2010. The patients were grouped into BLR group and RR group. Motor outcomes were divided into three groups on the basis of the angle of deviation after surgery: overcorrection(esotropia/phoria >5△), orthophoria(esotropia/phoria ≤5△to exotropia/phoria ≤10△), and undercorrection/recurrence(exotropia/phoria >10△).Titmus test was used to evaluate stereoacuity, the stereoacuity <800s of arc meaned the patients had stereopsis. Surgical outcome including motor criteria and sensory status were compared at postoperative 6, 12,24 mo and at 36 mo examination between groups. RESULTS: At 12, 24 mo after surgery, the motor outcomes had no difference(P >0.05) between groups.However, the motor outcomes at 6, 36 mo were signally different in each group, indicating the success rate in RR group at 6mo was higher than that in BLR group(83.02%vs 82.24%, P <0.05) but the result was contrary at the 3y examination(60.75% vs 43.40%, P <0.05). No statistical significance were found in the sensory outcomes between the groups at mean of 3.7y follow-up.CONCLUSION: The motor outcomes in RR group were better than in BLR group at 6mo after surgery, while the3 y outcomes were better in BLR group. This may be due to the recurrence rate of the BLR was lower than the RR group's. | Xian Yang Teng-Teng Man Qiao-Xia Tian Gui-Qiu Zhao Qing-Lan Kong Yan Meng Yan Gao Mei-Zhen Ning | 2014 | International Journal of Ophthalmology(English edition)2014，7，6： | 8 |
| 8 | Impact of different termination modes on atrial fibrillation termination in catheter ablation of persistent atrial fibrillation显示文摘 | WANG Ping DONG Jian-zeng LONG De-yong NING Man TANG Ri-bo YU Rong-hui XUE Zeng-ming SANG Cai-hua JIANG Chen-xi MA Chang-sheng | 2012 | Chinese Medical Journal2012，，11： | 7 |
| 9 | Efficacy of catheter ablation of atrial fibrillation beyond HATCH score显示文摘 | TANG Ri-bo DONG Jian-zeng LONG De-yong YU Rong-hui NING Man JIANG Chen-xi SANG Cai-hua LIU Xiao-hui MA Chang-sheng | 2012 | Chinese Medical Journal2012，，19： | 7 |
| 10 | Autotransfusion in the management of cardiac tamponade occurring during catheter ablation of atrial fibrillation显示文摘 | GAO Ling-yun TANG Ri-bo DONG Jian-zeng LIU Xing-peng LONG De-yong YU Rong-hui JIANG Chen-xi CHEN Gang SANG Cai-hua ZHANG Xin-yong NING Man MA Chang-sheng | 2010 | Chinese Medical Journal2010，，7： | 6 |
| 11 | PNPLA3 I148M variant in nonalcoholic fatty liver disease:Demographic and ethnic characteristics and the role of the variant in nonalcoholic fatty liver fibrosis显示文摘Patatin-like phospholipase domain-containing 3(PNPLA3 or adiponutrin) displays anabolic and catabolic activities in lipid metabolism,and has been reported to be significantly associated with liver fat content.Variousstudies have established a strong link between the 148 isoleucine to methionine protein variant(I148M) of PNPLA3 and liver diseases,including nonalcoholic fatty liver disease(NAFLD).However,detailed demographic and ethnic characteristics of the I148 M variant and its role in the development of nonalcoholic fatty liver fibrosis have not been fully elucidated.The present review summarizes the current knowledge on the association between the PNPLA3 I148 M variant and NAFLD,and especially its role in the development of nonalcoholic fatty liver fibrosis.First,we analyze the impact of demographic and ethnic characteristics of the PNPLA3 I148 M variant and the presence of metabolic syndrome on the association between PNPLA3 I148 M and NAFLD.Then,we explore the role of the PNPLA3 I148 M in the development of nonalcoholic fatty liver fibrosis,and hypothesize the underlying mechanisms by speculating a pro-fibrogenic network.Finally,we briefly highlight future research that may elucidate the specific mechanisms of the PNPLA3 I148 M variant in fibrogenesis,which,in turn,provides a theoretical foundation and valuable experimental data for the clinical management of nonalcoholic fatty liver fibrosis. | Li-Zhen Chen Yong-Ning Xin Ning Geng Man Jiang Ding-Ding Zhang Shi-Ying Xuan | 2015 | World Journal of Gastroenterology2015，21，3： | 6 |
| 12 | Multiple factors related to detrusor overactivity in Chinese patients with benign prostate hyperplasia显示文摘 | LIU Ning MAN Li-bo HE Feng HUANG Guang-lin WANG Hai L1 Gui-zhong WANG Jian-wei LUYan-wei | 2012 | Chinese Medical Journal2012，，21： | 6 |
| 13 | Effectiveness and safety of Chinese herbal medicines for hepatitis B virus-related acute-on-chronic liver failure:study protocol for a multicenter randomized controlled trial显示文摘OBJECTIVE:To conduct a multicenter randomized controlled trial of the efficacy of standardized Chinese herbal medicines(CHMs)against acuteon-chronic liver failure(ACLF)and provide reproducible and high-level evidence for clinical practice.METHODS:This is a prospective,multicenter,centrally randomized controlled trial.Patients diagnosed with hepatitis B virus-related ACLF(n=510)will be allocated to the standard medical therapy or CHM group at a 1∶1 ratio.Two CHMs will be used on the basis of the traditional Chinese medicine syndrome:Liangxue Jiedu granules for excess syndromes and Yiqi Jiedu granules for deficiency syndromes.The primary outcome is transplant-free survival at week 12.The secondary outcomes are(a)transplant-free survival at week 24,(b)liver function as assessed using the model for end-stage liver disease score at week 12,(c)liver function as assessed using the Child-Pugh score at week 12,and(d)the incidence of complications at week 12.DISCUSSION:The effectiveness and safety of CHM formulations will be assessed following treatment for ACLF.TRIAL REGISTRATION:The trial was registered at Clinical Trials.gov(NCT03577938)on June 24,2018. | Zhang Ning Zhou Chao Wang Lifu He Tingting Wang Yao Wang Yan Bai Yunfeng Li Jun Xiao Xiaohe Gong Man | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 5 |
| 14 | Outcome of catheter ablation of atrial fibrillation in patients with prior ischemic stroke显示文摘 | LI Song-nan KANG Jun-ping DU Xin HE Xiao-nan LONG De-yong YU Rong-hui TANG Ri-bo SANG Cai-hua JIANG Chen-xi NING Man DONG Jian-zeng MA Chang-sheng | 2013 | Chinese Medical Journal2013，，6： | 4 |
| 15 | Surface modification of PGP for a neutrophil–nanoparticle co-vehicle to enhance the anti-depressant effect of baicalein显示文摘Exploiting cells as vehicles combined with nanoparticles combined with therapy has attracted increasing attention in the world recently. Red blood cells, leukocytes and stem cells have been used for tumor immunotherapy, tissue regeneration and inflammatory disorders, and it is known that neutrophils can accumulate in brain lesions in many brain diseases including depression. N-Acetyl Pro–Gly–Pro(PGP) peptide shows high specific binding affinity to neutrophils through the CXCR2 receptor. In this study, PGP was used to modify baicalein-loaded solid lipid nanoparticles(PGP-SLNs) to facilitate binding to neutrophils in vivo. Brain-targeted delivery to the basolateral amygdala(BLA) was demonstrated by enhanced concentration of baicalein in the BLA. An enhanced anti-depressant effect was observed in vitro and in vivo. The mechanism involved inhibition of apoptosis and a decrease in lactate dehydrogenase release. Behavioral evaluation carried out with rats demonstrated that anti-depression outcomes were achieved. The results indicate that PGP-SLNs decrease immobility time, increase swimming time and climbing time and attenuate locomotion in olfactory-bulbectomized(OB) rats. In conclusion, PGP modification is a strategy for targeting the brain with a cell–nanoparticle delivery system for depression therapy. | Baoyu Chen Man Luo Jianming Liang Chun Zhang Caifang Gao Jue Wang Jianxin Wang Yongji Li Desheng Xu Lina Liu Ning Zhang Huijun Chen Jing Qin | 2018 | Acta Pharmaceutica Sinica B2018，8，1： | 4 |
| 16 | Emphysematous Pyelonephritis Treated with Vacuum Sealing Drainage显示文摘 | Hai-Dong Wang Xiao-Fei Zhu Xiao Xu Gui-Zhong Li Ning Liu Feng He Li-Bo Man | 2017 | Chinese Medical Journal2017，，2： | 4 |
| 17 | Association between Selenium in Soil and Diabetes in Chinese Residents Aged 35–74 Years:Results from the 2010 National Survey of Chronic Diseases and Behavioral Risk Factors Surveillance显示文摘Objective To explore the association between soil selenium levels and the risk of diabetes in Chinese adults aged 35–74 years.Methods Data for this study were derived from the China Chronic Diseases and Behavioral Risk Factors Surveillance 2010 survey.Selenium concentrations in soil were obtained from the Atlas of Soil Environmental Background Values in China.A two-level binary logistic regression model was used to determine the association between soil selenium concentrations and the risk of diabetes,with participants nested within districts/counties.Results A total of 69,332 participants aged 35–74 years,from 158 districts/counties were included in the analysis.Concentrations of selenium in soil varied greatly across the 158 districts/counties,with a median concentration of 0.219 mg/kg(IQR:0.185–0.248).The results showed that both Quartile 1(0.119–0.185 mg/kg)and Quartile 4(0.249–0.344 mg/kg)groups were positively associated with diabetes compared to a soil selenium concentration of 0.186–0.219 mg/kg(Quartile 2),crude odds ratios(ORs)(95%CI)were 1.227(1.003–1.502)and 1.280(1.048–1.563).The P values were 0.045 and 0.013,for Quartile 1 and Quartile 4 groups,respectively.After adjusting for all confounding factors of interest,the Quartile 1 group became non-significant,and the Quartile 4 group had an adjusted OR(95%CI)of 1.203(1.018–1.421)relative to the reference group(Quartile 2),the P values was 0.030.No significant results were seen for the Quartile 3 group(0.220–0.248 mg/kg)compared to the reference group.Conclusion Excessive selenium concentrations in soil could increase the risk of diabetes among Chinese adults aged 35–74 years. | WANG Qi Qi YU Shi Cheng XU Cheng Dong LIU Jian Jun LI Yuan Qiu ZHANG Man Hui LONG Xiao Juan LIU Yun Ning BI Yu Fang ZHAO Wen Hua YAO Hong Yan | 2020 | Biomedical and Environmental Sciences2020，33，4： | 3 |
| 18 | Efficacy of a novel endotoxin adsorber polyvinylidene fluoride fiber immobilized with L-serine ligand on septic pigs显示文摘A novel adsorber,polyvinylidene fluoride matrix immobilized with L-serine ligand (PVDF-Ser),was developed in the present study to evaluate its safety and therapeutic efficacy in septic pigs by extracorporeal hemoperfusion.Endotoxin adsorption efficiency (EAE) of the adsorber was firstly measured in vitro.The biocompatibility and hemodynamic changes during extracorporeal circulation were then evaluated.One half of 16 pigs receiving lipopolysaccharide (Escherichia coli O111:B4,5 μg/kg) intravenously in 1 h were consecutively treated by hemoperfusion with the new adsorber for 2 h.The changes of circulating endotoxin and certain cytokines and respiratory function were analyzed.The 72 h-survival rate was assessed eventually.EAE reached 46.3% (100 EU/ml in 80 ml calf serum) after 2 hcirculation.No deleterious effect was observed within the process.The plasma endotoxin,interleukin-6 (IL-6),and tumor necrosis factor-α (TNF-α) levels were decreased during the hemoperfusion.Arterial oxygenation was also improved during and after the process.Furthermore,the survival time was significantly extended (>72 h vs.47.5 h for median survival time).The novel product PVDF-Ser could adsorb endotoxin with high safety and efficacy.Early use of extracorporeal hemoperfusion with the new adsorber could reduce the levels of circulating endotoxin,IL-6,and TNF-α,besides improve respiratory function and consequent 72 h-survival rate of the septic pigs.Endotoxin removal strategy with blood purification using the new adsorber renders a potential promising future in sepsis therapy. | Jian-ping GAO Man HUANG Ning LI Peng-fei WANG Huan-lin CHEN Qiu-ping XU | 2011 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2011，12，4： | 3 |
| 19 | Ecological Offsetting in China's Coastal Wetlands: Existing Challenges and Strategies for Future Improvement显示文摘Land-use changes in coastal wetlands have led to a worldwide degradation of marine coastal ecosystems and a loss of the ecological services they provide. Ecological offsetting is a popular strategy and an effective mitigation measure for ecosystems that have been degraded, damaged, or destroyed and is critical for habitats where natural recovery is hindered. However, the current understanding of the theory and practice of ecological offsetting for coastal wetlands is extremely limited in many developing countries. We conducted a review of ecological offsetting for coastal wetlands projects and studies in China in 1979–2017 to explore the application and limitations of ecological offsetting theory. It was found that China's coastal ecological offsetting regime has recently entered a rapidly developing stage, with an increasing number of different types of offsetting projects conducted, but theoretical research lags behind practical applications. Considerable governmental, social, technological and ethical challenges remain to resolve. Coastal ecological offsetting schemes have been inconsistent in meeting conservation objectives or preventing net losses because of the challenges of ensuring they are fully consistent in practice(mainly in-kind offsets) and theory(mainly out-of-kind offsets). Ecological offsetting projects were primarily implemented by government, developers, and non-profit organizations. The available funding of coastal ecological offsetting projects is insufficient, which makes ecological offsetting a risky operation. Therefore, we propose strategies for improvement that integrate the consideration of theoretical and practical challenges in the offsetting process, while providing a scientific basis and directional guidance for the future practice of biodiversity conservation and environmental management. | YU Shuling CUI Baoshan XIE Chengjie MA Xu MAN Ying NING Zhonghua | 2019 | Chinese Geographical Science2019，29，2： | 3 |
| 20 | Rhubarb-based Chinese herbal formulae for hepatic encephalopa-thy:a systematic review and Meta-analysis显示文摘OBJECTIVE: To evaluate the effectiveness and safety of rhubarb-based Chinese herbal formulae(RCHF), which are widely used to treat hepatic encephalopathy(HE) in China.METHODS: Nine online databases were searched from inception to November 22, 2016. Eligible studies were randomized controlled trials of Traditional Chinese Medicine(TCM) treatment for adult patients(≥ 18 years old) with HE. Outcomes such as mortality rate, clinical response rate, blood ammonia level, and alanine aminotransferase were evaluated between TCM group and control group.RESULTS: Thirty studies involving 2661 HE patients were analyzed. Most studies used RCHF treatment.Compared with conventional treatment as usual,lactulose, and vinegar, RCHF were associated with significant improvement in clinical response rate[risk ratio(RR) = 1.33, 95% confidence interval(CI) =1.25, 1.43, I2= 0%; RR = 1.26, 95% CI = 1.14, 1.38, I2=22%; and RR = 1.19, 95% CI = 1.06, 1.33, I2= 0%, respectively] and significant reductions in levels of blood ammonia and alanine aminotransferase. Only minor RCHF-associated adverse events, such as abdominal pain(0.3%), anal tenesmus(0.3%), and diarrhea(2.3%), were reported, and there were no significant differences in these events between the treatment group and the three types of control group.CONCLUSION: The findings suggest that RCHF may be an alternative treatment option for HE patients. More rigorous multicenter studies with larger samples and longer observational periods are needed to confirm these findings. | Zhang Ning Zhou Shuangnan Xiao Xiaohe Wanq Zhen Bai Yunfeng He Tingting Zhou Chao Wang Yao Kun Zhou Wang Zhongxia Liu Bing Larry J.Prokop Matthew C.Hernandez Li Jun Gong Man | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员