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| 1 | Soluble CD40 ligand in prediction of acute severe pancreatitis显示文摘瞄准:在胰腺炎严厉估计可溶的 CD40L (sCD40L ) 的早可预测性。方法:在 2000 年 2 月和 2003 年 2 月之间,有尖锐胰腺炎的 279 个连续病人有希望地在我们的学习被注册。在这份报告, 40 个病人与温和并且有严重胰腺炎的 40 个病人随机被学习。sCD40L 集中被测量在承认以后的 48 个小时。结果:sCD40L 层次显著地更高在在严重胰腺炎的承认以后的 48 个小时比在温和胰腺炎。用 1000 的截止,检测疾病的一堂严重功课的 sCD40L 的 pg/L,敏感和特性为 CRP 与 72% 和 81% 相比分别地是 78% 和 62% 。发现那 CRP 的逻辑回归分析统计上是唯一的能检测疾病的一堂严重功课的重要标记。结论:这些调查结果显示 CRP 仍然是一个珍贵标记而 sCD40L 层次应该在进一步的研究被估计,决定尖锐胰腺炎的严厉和预后。 | Jean Louis Frossard Philippe Morel Brenda Kwak Catherine Pastor Thierry Berney Léo Buhler Alain Von Laufen Sandrine Demulder Francois Mach | 2006 | World Journal of Gastroenterology2006,12,10: | 2 |
| 2 | Genetic improvement of Trichoderma ability to induce systemic resistance显示文摘The beneficial applications of Trichoderma spp. in agriculture include not only the control of plant pathogens, but also the improvement of plant growth, micronutrient availability, and plant tolerance to abiotic stress. In addition, it has been suggested that these fungi are able to increase plant disease resistance by activating induced systemic resistance (ISR) . The mode of action of these beneficial fungi in the Trichoderma -plant-pathogen interaction are many, complex and not completely understood. Numerous lytic enzymes have been characterized, the encoding genes (ech42 gluc78, nag1 from T. atroviride strain P1) cloned, and their role in biocontrol demonstrated. The corresponding biocontrol-related inducible promoters have been used in a reporter system based on the Aspergillus niger glucose oxidase gene (goxA) to monitor biocontrol activity. Glucose oxidase catalyzes the oxygen-dependent oxidation of D-glucose to D-glucono-1,5-lactone and hydrogen peroxide; this latter compound is known to have an antifungal effect and activate the plant defence cascade, thus increasing resistance to pathogen attack. T. atroviride P1 transformants with various promoters gox were tested as seed coating treatments on bean seeds planted in soil infested with a soilborne fungal pathogen. Successively, the emergent leaves were inoculated with a foliar pathogen to determine the effect of the GOX transformants on biocontrol and resistance to pathogen attack. Inoculations with the P1-GOX transformants not only reduced disease symptoms caused by a soil pathogen, but also the lesions of various foliar pathogens applied far from the Trichoderma colonization, thus activating ISR. A similar approach is being use to genetically improve T. harzianum T22, a rhizosphere competent and commercially marketed strain not transformed yet, by using four different gox gene constructs under the control of constitutive and inducible promoters. Plasmids have been introduced in Trichoderma by protoplasts co-transformation. hygromicin resistant progeny selected, and mitotically stable transformants analysed to confirm the presence of the novel enzyme activity. Progenies are being tested for biocontrol ISR inducing activity. | Ciliento R Woo S L Di Benedetto P Ruocco M Scala F Soriente I Ferraioli S Brunner K Zeilinger S Mach R L Lorito M | 2004 | 浙江大学学报(农业与生命科学版)2004,30,4: | 2 |
| 3 | Role of four major cellulases in triggering of cellulase gene expression by cellulose in Trichoderma reesei 显示文摘 | Seiboth B Hakola S Mach R L | 1997 | J Bacteriol1997,179,17: | 1 |
| 4 | Role of four major cellulases in triggering of cellulase gene expression by cellulose in Trichoderma reesei显示文摘 | Seiboth B Hakola S Mach R L | 1997 | Journal of Bacteriology1997,179,17: | 1 |
| 5 | Role of four major cellulases in triggering of ceUulase gene expression by cellulose in Trichoderma reesei 显示文摘 | SE1BOTH B HAKOLA S MACH R L | 1997 | J Baeteriol1997,179,17: | 1 |
| 6 | Optimisation of porcine oocyte activation following nuclear transfer显示文摘 | TAO T MACH~TY Z ABEYDEERA L R | 2000 | Zygote2000,8,1: | 1 |
| 7 | Generation of Arabidopsis thalianna plants with complex N-glycans lacking β1,2-linked xylose and coreα1,3-linked fucose显示文摘 | Strasser R Altmann F Mach L | 2004 | FEBS Lett2004,561,13: | 1 |
| 8 | Estimation of Drug-Protein Binding Parameters on Assuming the Validity of Thermodynamic Equilibrium显示文摘 | Soltes L Mach M | 2002 | Journal of Chromatography B2002,768,1: | 1 |
| 9 | Phylogenetic relationship of Fusarium langsethiae to Fusarium poaeand Fusarium sporotrichioidesas inferred by IGS,ITS,β-tubulin sequences and UP-PCR hybridization analysis显示文摘 | Mattila T Mach R L Alekhina I A | 2004 | International Journal of Food Microbiology2004,95,3: | 1 |
| 10 | Ca2+-calmodulin antagonists interfere with xylanase formation andsecretion in Trichoderma reesei显示文摘 | MACH R L ZEILINGER S KRISTUFEK D | 1998 | Biochimica et BiophysicaActa1998,1403,: | 1 |
| 11 | Regulation of gene expressionin industrial fungi:Trichoderma显示文摘 | MACH R L ZEILINGER S | 2003 | Applied MicrobiologicalBiotechnology2003,60,: | 1 |
| 12 | Role of fourmajor cellulases in triggering of cellulose gene expression bycellulose in Trichoderma reesei显示文摘 | SEIBOTH B HAKOLA S MACH R L | 1997 | Journal of Bacteriology1997,179,17: | 1 |
| 13 | Phylogenetic relation- ship of Fusarium langsethiae to Fusarium poae and Fusarium spo- rotrichioides as inferred by IGS, ITS, h-tubulin sequences and UP- PCR hybridization analysis显示文摘 | Yli-Mattila T Mach R L Alekhina I A | 2004 | International Journal of Food Micro- biology2004,95,: | 1 |
| 14 | Trichoderma:from genes to biocontrol显示文摘 | KUBICEK C P MACH R L PETERBAUER C K | 2001 | Journal of plant pathology2001,83,2: | 1 |
| 15 | Regulation of gene expression in industrial fungi:Trichoderma显示文摘 | Mach R L Zeilinger S | | 0,,05: | 1 |
| 16 | Ueber einen interferenzrefraktor 显示文摘 | Mach L | | Zeitschrift Ftir Instrumentenkunde0,12,: | 1 |
| 17 | Organic phosphorus and carbon in marine sediments显示文摘 | MACH D L RAMIREZ A HOLLAND H D | 1987 | American J Sci1987,287,5: | 1 |
| 18 | Determination of Escherichia coli Contamination with Chromocult Coliform Agar Showed a High Level of Discrimination Efficiency for Differing Fecal Pollution Levels in Tropical Waters of Kampala, Uganda显示文摘 | Byamukama D Kansiime F Mach R L | | Appl En0,,: | 1 |
| 19 | Xyr1 receives the lactose induction signal and regulates lactose metabolism in Hypocrea jecorina显示文摘 | Stricker A R Steiger M G Mach R L | | 0,,21: | 1 |
| 20 | Transformation of Trichoderma reesei based on hygromycin B resistance using homologous expression signals显示文摘 | MACH R L SCHINDLER M KUBICEK C P | 1994 | Curr Genet1994,25,6: | 1 |