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| 1 | Treatment of central precocious puberty by GnRH analogs: long-term outcome in men显示文摘在男孩,中央早熟的发身(CPP ) 是以前垂体促性腺激素分泌物驾驶的第二等的性别特征的外观 9 年的年龄。在最后年里,在 CPP 的处理的相关改进被完成了。因为 CPP 在男孩是稀罕的,这个问题上的报纸的多数集中于女孩并且不关于结束结果和安全探讨男病人的特定的特征。在现在的纸,有在男人的 GnRH 类似物的 CPP 管理的最近的进展被总结。在未经治疗、对待的病人的结束结果被最近出版的文学的分析也在男人在 CPP 的治疗上考察。可得到的数据显示没有重要不利短期、长期的效果,有 GnRH 类似物的那治疗能改进最后的高度进目标高度的范围,但是病人的更大的系列的更长的后续是仍然要求了得出权威的结论。 | Silvano Bertelloni Dick Mul | 2008 | Asian Journal of Andrology2008，10，4： | 13 |
| 2 | Metabolic syndrome in hypertensive patients:An unholy alliance显示文摘For many years, it has been recognized that hypertension tends to cluster with various anthropometric and metabolic abnormalities including abdominal obesity, elevated triglycerides, reduced high-density lipoprotein cholesterol, glucose intolerance, insulin resistance and hyperuricemia. This constellation of various conditions has been transformed from a pathophysiological concept to a clinical entity, which has been defined metabolic syndrome(MetS). The consequences of the MetS have been difficult to assess without commonly accepted criteria to diagnose it. For this reason, on 2009 the International Diabetes Federation, the American Heart Association and other scientific organizations proposed a unified MetS definition. The incidence of the MetS has been increasing worldwide in parallel with an increase in overweight and obesity. The epidemic proportion reached by the MetS represents a major public health challenge, because several lines of evidence showed that the MetS, even without type 2 diabetes, confers an increased risk of cardiovascular morbidity and mortality in different populations including also hypertensive patients. It is likely that the enhanced cardiovascular risk associated with MetS in patients with high blood pressure may be largely mediated through an increased prevalence of preclinical cardiovascular and renal changes, such as left ventricular hypertrophy, early carotid atherosclerosis, impaired aortic elasticity, hypertensive retinopathy and microalbuminuria. Indeed, many reports support this notion, showing that hypertensive patients with MetS exhibit, more often than those without it, these early signs of end organ damage, most of which are recognized as significant independent predictors of adverse cardiovascular outcomes. | Giuseppe Mulè IIenia Calcaterra Emilio Nardi Giovanni Cerasola Santina Cottone | 2014 | World Journal of Cardiology2014，6，9： | 10 |
| 3 | Liver hemangioma and vascular liver diseases in patients with systemic lupus erythematosus显示文摘AIM:To investigate whether systemic lupus erythematosus (SLE) is associated with benign focal liver lesions and vascular liver diseases, since these have been occasionally reported in SLE patients. METHODS:Thirty-five consecutive adult patients with SLE and 35 age-and sex-matched healthy controls were evaluated. Hepatic and portal vein patency and presence of focal liver lesions were studied by colour-Doppler ultrasound, computerized tomography and magnetic resonance were used to refine the diagnosis, clinical data of SLE patients were reviewed. RESULTS:Benign hepatic lesions were common in SLE patients (54% vs 14% controls, P < 0.0001), withhemangioma being the most commonly observed lesion in the two groups. SLE was associated with the presence of single hemangioma [odds ratios (OR) 5.05; 95% confidence interval (CI) 1.91-13.38] and multiple hemangiomas (OR 4.13; 95% CI 1.03-16.55). Multiple hemangiomas were associated with a longer duration of SLE (9.9 ± 6.5 vs 5.5 ± 6.4 years; P = 0.04). Imaging prior to SLE onset was available in 9 patients with SLE and hemangioma, showing absence of lesions in 7/9. The clinical data of our patients suggest that SLE pos- sibly plays a role in the development of hemangioma. In addition, a Budd-Chiari syndrome associated with nodular regenerative hyperplasia (NRH), and a NRH associated with hepatic hemangioma were observed, both in patients hospitalized for abdominal symptoms, suggesting that vascular liver diseases should be specifically investigated in this population. CONCLUSION:SLE is associated with 5-fold increased odds of liver hemangiomas, suggesting that these might be considered among the hepatic manifestations of SLE. | Annalisa Berzigotti Marilena Frigato Elena Manfredini Lucia Pierpaoli Rita Mulè Carolina Tiani Paola Zappoli Donatella Magalotti Nazzarena Malavolta Marco Zoli | 2011 | World Journal of Gastroenterology2011，17，40： | 5 |
| 4 | 高血压患者颈动脉粥样硬化和脉压及肾血流动力学的关系显示文摘动脉粥样硬化结构性损害、动脉硬化、脉压和肾血流动力学之间可能相互作用与相互影响。肾阻力指数(renal resistance index,RRI)被认为是可预测全身血管变化的一个很好的指标。 | Geraci G MulèG Costanza G Mogavero M Geraci C Cottone S 陈云 叶鹏 | 2016 | 中华高血压杂志2016，24，6： | 3 |
| 5 | Laser Doppler velocimeter based on the self-mixing effect in a fiber-coupled semiconductor laser:theory显示文摘 | MH Koelink M Slot FFM de Mul | 1992 | Applied Optics1992，31，18： | 1 |
| 6 | Reversal of in vitro cellular MRPI and MRP2 mediated vincristine resistance by the flavonoid myricetin 显示文摘 | VAN ZANDEN JJ DE MUL A WORTELBOER HM | 2005 | Biochem Pharmacol2005，69，11： | 1 |
| 7 | Feasibility study towards a Cu/K/Mo/(C1) soot oxidation catalyst for application in diesel exhaust gases显示文摘 | Neeft J P A Schipper W Mul G | 1997 | Appl Catal B1997，11，34： | 1 |
| 8 | Cel lular reaction on the anterior surface of 4 types of intraocular lens es显示文摘 | Mul lner-Eidenbock A Amon M Schauersberger J | 2001 | J Cataract Refract Surg2001，27，5： | 1 |
| 9 | Aspergil us endocarditis presenting as femoral artery embolism显示文摘 | Verghese S Maria CF Mul aseri AS | | 0，，5： | 1 |
| 10 | Condensed Monte Carlo simulations for the description of light transport显示文摘 | Graaff R Koelink M H Mul F F M | 1993 | Appl Opt1993，，4： | 1 |
| 11 | Calculations of dietary exposure to aerylamide 显示文摘 | Polly E Boon Anika de Mul Hilko van der Voet | 2005 | Mutation Research2005，580，12： | 1 |
| 12 | Catalytic oxidation of model soot by metal chlorides 显示文摘 | Mul G Kapteijn F Moulijn J A | 1997 | Applied Catalysis B: Environmental1997，12，： | 1 |
| 13 | Differentiation of Fusarium verticillioides from banana fruits by IGS and EF-1α sequence analyses 显示文摘 | Mirete S V zquez C Mul G | 2004 | Eur J Plant Pathol2004，110，： | 1 |
| 14 | β-catenin antisense studies in embryonic liver cultures: Role in proliferation, apoptosis, and lineage specification显示文摘 | Satdarshan P.S. Monga Hardarshan K. Monga Xinping Tan Karen Mulé Peter Pediaditakis George K. Michalopoulos | 2003 | Gastroenterology2003，，1： | 1 |
| 15 | Increased risk of thromboembolism in esophageal cancer patients treated with neoadjuvant chemoradiotherapy显示文摘 | Dirk J. Bosch Quirine A. Van Dalfsen Véronique E.M. Mul Geke A.P. Hospers John Th.M. Plukker | 2013 | The American Journal of Surgery2013，，： | 1 |
| 16 | Use of selenium in chemoprevention of bladder cancer 显示文摘 | Brinkman M Buntinx F Muls E | 2006 | Lancet Oncol2006，7，9： | 1 |
| 17 | Treatment of thoracolumbar burst fractures without neurologic deficit by indirect reduction and posterior instrumentation:bisegmental stabilization with monosegmental fusion显示文摘 | Mul er U Berlemann U Sledge J | | 0，，04： | 1 |
| 18 | The contact between arbitrarily curved bodies of finite dimensions 显示文摘 | de Mul J M Kalker J J Fredriksson B | 1986 | Journal of Tribology1986，108，1： | 1 |
| 19 | Final height after gonadotropin rleasing hormone agonist treatment for central precocious puberty显示文摘 | Mul D Oostdijk W Otten BJ | 2000 | J Pediatr Endocrinol Metab2000，，： | 1 |
| 20 | Fiber-coupled self-mixing laser diode Doppler velocimeter:technical aspects and flow velocity profile disturbances in water and blood flows显示文摘 | M H Koelink F F M de Mul A L Weijers | 1994 | Applied Optics1994，33，24： | 1 |
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