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1157篇 您的检索式:作者名="MONTOYA"
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1精子DNA损伤的机制和临床应用显示文摘在男性配子各种不同的DNA异常中,DNA断裂最为常见,尤其是在不育症患者中。目前越来越多的研究表明,DNA断裂并不显著影响精子细胞的存活率、活动率、形态以及与卵细胞的结合能力。研究还证明,卵母细胞在一定程度上可以修复受损的DNA,其修复程度依赖于精子细胞DNA的损伤类型和卵母细胞的质量。因此,研究精子DNA断裂(SDF)在自然分娩或辅助生殖技术助孕中对胚胎发育、胚胎着床、妊娠结果、子代健康的影响变得非常重要。至今,针对SDF对生殖的影响的研究极少,且研究报道的结论很不一致。导致这种不一致的原因可能与检测SDF的手段不同、实验设计不同和精液标本选择标准不同有关。因此,目前还不能确定是否将SDF检测拽术砬用于受精评估和ART技术中。这表明,制定SDF检测技术的标准化方法势在必行,另外关于SDF对ART的影响有必要进行进一步的临床研究。Lara Tamburrino Sara Marchiani Margarita Montoya Francesco Elia Marino Ilaria Natali Marta Cambi Gianni Forti Elisabetta Baldi Monica Muratori 2012Asian Journal of Andrology2012,14,1:16
2On the road to smart biomaterials for bone research: definitions, concepts, advances, and outlook显示文摘The demand for biomaterials that promote the repair,replacement,or restoration of hard and soft tissues continues to grow as the population ages.Traditionally,smart biomaterials have been thought as those that respond to stimuli.However,the continuous evolution of the field warrants a fresh look at the concept of smartness of biomaterials.This review presents a redefinition of the term“Smart Biomaterial”and discusses recent advances in and applications of smart biomaterials for hard tissue restoration and regeneration.To clarify the use of the term“smart biomaterials”,we propose four degrees of smartness according to the level of interaction of the biomaterials with the bio-environment and the biological/cellular responses they elicit,defining these materials as inert,active,responsive,and autonomous.Then,we present an up-to-date survey of applications of smart biomaterials for hard tissues,based on the materials’responses(external and internal stimuli)and their use as immune-modulatory biomaterials.Finally,we discuss the limitations and obstacles to the translation from basic research(bench)to clinical utilization that is required for the development of clinically relevant applications of these technologies.Carolina Montoya Yu Du Anthony L.Gianforcaro Santiago Orrego Maobin Yang Peter I.Lelkes 2021Bone Research2021,9,2:7
3非洲猪瘟——威胁全球猪业的重要疾病重现江湖:基本概况显示文摘近期,非洲猪瘟(African Swine Fever,ASF)已经从撒哈拉以南的非洲国家传播到南高加索地区、俄罗斯联邦部分地区和东欧。在新一轮流行病学事件中,此次流行的ASF与其在非洲的情况有相似性,但仍有重要的差异,包括野猪的实际影响。更好地了解这种新形势能够有效地控制该病,并阻止该病的进一步传播。本文将会对这些不同情境进行比较,并讨论非洲猪瘟病毒(African Swine Fever Virus,ASFV)毒株发病机理的最新信息、动物对感染的免疫应答以及疫苗的研发前景等。本文还将讨论现有知识的差异和未来控制展望。贾良梁(译) 夏俊花(审) P. J. Sánchez-Cordón M. Montoya A. L. Reis L. K. Dixon 2019国外畜牧学(猪与禽)2019,39,4:3
4非洲猪瘟——威胁全球猪业的重要疾病重现江湖:发病机制和疫苗研发显示文摘本文是《非洲猪瘟——威胁全球猪业的重要疾病重现江湖》的第二部分,主要介绍非洲猪瘟病毒东欧分离株的试验性发病机制和疫苗研发情况。贾良梁(译) 夏俊花(审) P. J. Sánchez-Cordón M. Montoya A. L. Reis L. K. Dixon 2019国外畜牧学(猪与禽)2019,39,4:3
5High-throughput prediction of the ground-state collinear magnetic order of inorganic materials using Density Functional Theory显示文摘We present a robust,automatic high-throughput workflow for the calculation of magnetic ground state of solid-state inorganic crystals,whether ferromagnetic,antiferromagnetic or ferrimagnetic,and their associated magnetic moments within the framework of collinear spin-polarized Density Functional Theory.This is done through a computationally efficient scheme whereby plausible magnetic orderings are first enumerated and prioritized based on symmetry,and then relaxed and their energies determined through conventional DFT+U calculations.This automated workflow is formalized using the atomate code for reliable,systematic use at a scale appropriate for thousands of materials and is fully customizable.The performance of the workflow is evaluated against a benchmark of 64 experimentally known mostly ionic magnetic materials of non-trivial magnetic order and by the calculation of over 500 distinct magnetic orderings.A non-ferromagnetic ground state is correctly predicted in 95% of the benchmark materials,with the experimentally determined ground state ordering found exactly in over 60% of cases.Knowledge of the ground state magnetic order at scale opens up the possibility of high-throughput screening studies based on magnetic properties,thereby accelerating discovery and understanding of new functional materials.Matthew Kristofer Horton Joseph Harold Montoya Miao Liu Kristin Aslaug Persson 2019npj Computational Materials2019,,1:3
6底吹法精炼锰合金显示文摘对采用氧气顶吹将高碳锰铁从 C6.5—7.0%脱碳至低于1.5%的中碳锰铁生产的传统方法作了一些改变。这些改变包括:利用设置在转炉底部径向上的风嘴,在最低的氧气流速率下利用硅锰合金快速地获得最佳的脱碳温度及具有较好锰收得率程金属和炉渣容易分离的合适的炉渣。ATANASIO MONTOYA M. E 毕传泰 1991铁合金1991,,5:3
7运用手机进行改进的个体化健康促进干预以提高HIV阳性冰毒使用者的服药依从性显示文摘运用手机进行健康促进( mobile health, mHealth)干预在提高抗病毒治疗依从性上显示了明显的效果,但是对于HIV阳性的冰毒使用者来说,有必要对干预内容进行有效的调整,以满足该人群的特殊需要。Montoya JL Georges S Poquette A 胡翼飞 吴迪 2014中华预防医学杂志2014,48,11:2
8Kinetics and mechanisms of the catalytic thermal cracking of asphaltenes adsorbed on supported nanoparticles显示文摘The production of heavy and extra-heavy oil is challenging because of the rheological properties that crude oil presents due to its high asphaltene content.The upgrading and recovery processes of these unconventional oils are typically water and energy intensive,which makes such processes costly and environmentally unfriendly.Nanoparticle catalysts could be used to enhance the upgrading and recovery of heavy oil under both in situ and ex situ conditions.In this study,the effect of the Ni-Pd nanocatalysts supported on fumed silica nanoparticles on post-adsorption catalytic thermal cracking of n-C_7 asphaltenes was investigated using a thermogravimetric analyzer coupled with FTIR.The performance of catalytic thermal cracking of n-C_7asphaltenes in the presence of NiO and PdO supported on fumed silica nanoparticles was better than on the fumed silica support alone.For a fixed amount of adsorbed n-C_7asphaltenes(0.2 mg/m^2),bimetallic nanoparticles showed better catalytic behavior than monometallic nanoparticles,confirming their synergistic effects.The corrected OzawaFlynn-Wall equation(OFW) was used to estimate the effective activation energies of the catalytic process.The mechanism function,kinetic parameters,and transition state thermodynamic functions for the thermal cracking process of n-C_7 asphaltenes in the presence and absence of nanoparticles are investigated.Tatiana Montoya Blanca L.Argel Nashaat N.Nassar Camilo A.Franco Farid B.Cortés 2016Petroleum Science2016,13,3:2
9Diagnostics in assisted human reproduction显示文摘Juan Manuel Montoya Alejandra Bernal Claudia Borrero 2002Reproductive BioMedicine Online2002,,2:2
10Toxoplasmosis显示文摘JG Montoya O Liesenfeld 2004The Lancet2004,,9425:2
11豌豆颗粒的大小对生长猪可消化能的影响显示文摘研究旨在确定不同颗粒大小的11种豌豆对生长猪可消化能(DE)的影响和确定其中5种不同颗粒大小豌豆的体外淀粉水解能力。各品种豌豆通过5.4、3.28和0.74mm筛孔尺寸过筛,其几何平均粒径(GMPS)分别为1035、649和156μm。204只生长猪(28±2kg;分为34个处理组,每组6只)饲喂以谷物、豆粕、预混料或33种以豌豆为主组成的基础日粮(0.3豌豆和0.7基础日粮),并进行补充饲喂硅藻土(消化标记),共进行13d。粪便在饲喂的最后3d进行收取。其中3种GMPS的5个豌豆品种分别与胃蛋白酶作用120min,与以胰酶、异麦芽糖酶和麦芽糖酶的混合物作用240min。豌豆的DE值的变化范围为13.38~16.05MJ.kg-1。随GMPS(P<0.01)的增加,DE平均值(16.1,14.7和14.0MJ.kg-1)呈线性下降。淀粉水解程度的差异受'豌豆品种×GMPS'相互作用影响。在DE值与淀粉水解程度之间存在正相关的关系(r=0.62,P=0.02)。试验表明,随正GMPS的下降,各种豌豆的DE值呈线性增加。水解淀粉和GMPS可用来决定豌豆品种之间的差异。Carlos A Montoya L Pascal L 2012饲料博览2012,,5:2
12Predicting aqueous stability of solid with computed Pourbaix diagram using SCAN functional显示文摘In this work,using the SCAN functional,we develop a simple method on top of the Materials Project(MP)Pourbaix diagram framework to accurately predict the aqueous stability of solids.We extensively evaluate the SCAN functional’s performance in computed formation enthalpies for a broad range of oxides and develop Hubbard U corrections for transition-metal oxides where the standard SCAN functional exhibits large deviations.The performance of the calculated Pourbaix diagram using the SCAN functional is validated with comparison to the experimental and the MP PBE Pourbaix diagrams for representative examples.Benchmarks indicate the SCAN Pourbaix diagram systematically outperforms the MP PBE in aqueous stability prediction.We further show applications of this method in accurately predicting the dissolution potentials of the state-of-the-art catalysts for oxygen evolution reaction in acidic media.Zhenbin Wang Xingyu Guo Joseph Montoya Jens K.Nørskov 2020npj Computational Materials2020,,1:2
13Recent advances in the biogeochemistry of nitrogen in the ocean显示文摘NAQVI S W A VOSS M MONTOYA J P 2008Biogeosciences Discus- sions2008,5,:1
14Development of monoclonal ELISAs for azinphos-methyl:Hapten synthesis and antibody production显示文摘MERCADER J V MONTOYA A 1999J Agric Food Chem1999,47,3:1
15Ntegrations of the hepatitis B virus(HBV) and human papil]omavirus (HPV) into the human telomersse reverse transcriptase (hTERT) gene in liver and cervical cancers 显示文摘Ferber MJ Montoya DP Yu C 2003Oncogene2003,22,24:1
16Porcine circovirus type 2-induced intcrleukin-10 modulate recall antigen response显示文摘Kekarainen T Montoya M Mateu E 2008J Gcn Virol2008,,89:1
17Neuroleptic malig- nant syndrome in Mexico显示文摘Montoya A Ocampo M Torres -Ruiz A 2003Can J Clin Pharmacol2003,10,3:1
18Inhibitory effects of sulphated flavonoids isolated from Flaveria bidentis on platelet aggregation显示文摘Hugo A. Guglielmone Alicia M. Agnese Susana C. Nú?ez Montoya José L. Cabrera 2004Thrombosis Research2004,,6:1
19tRNA punctuation model of RNA processing in human mitochondria显示文摘Ojala D Montoya J Attardi G 1981Nature1981,290,:1
20An study on acceleratedcorrosion testing of wreathing steel显示文摘Montoya P Dtaza I Granizo N 2013Materials Chemistry andPhysics2013,142,1:1
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