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| 1 | Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial显示文摘 | Roger Stupp Monika E Hegi Warren P Mason Martin J van den Bent Martin JB Taphoorn Robert C Janzer Samuel K Ludwin Anouk Allgeier Barbara Fisher Karl Belanger Peter Hau Alba A Brandes Johanna Gijtenbeek Christine Marosi Charles J Vecht Karima Mokhtari Piet | 2009 | Lancet Oncology2009，，5： | 4 |
| 2 | Clinical classification of symptomatic heterotopic pancreas of the stomach and duodenum:A case series and systematic literature review显示文摘BACKGROUND Heterotopic pancreas(HP)is an aberrant anatomic malformation that occurs most commonly in the upper gastrointestinal tract.While the majority of heterotopic pancreatic lesions are asymptomatic,many manifest severe clinical symptoms which require surgical or endoscopic intervention.Understanding of the clinical manifestations and symptoms of HP is limited due to the lack of large volume studies in the literature.The purpose of this study is to review symptomatic cases at a single center and compare these to a systematic review of the literature in order to characterize common clinical manifestations and treatment of this disease.AIM To classify the common clinical manifestations of heterotopic pancreas.METHODS A retrospective review was conducted of pathologic samples containing heterotopic pancreas from 2000-2018.Review was limited to HP of the upper gastrointestinal tract due to the frequency of presentation in this location.Symptomatic patients were identified from review of the medical records and clinical symptoms were tabulated.These were compared to a systematic review of the literature utilizing Pub Med and Embase searches for papers pertaining to heterotopic pancreas.Publications describing symptomatic presentation of HP were selected for review.Information including demographics,symptoms,presentation and treatment were compiled and analyzed.RESULTS Twenty-nine patient were identified with HP at a single center,with six of these identified has having clinical symptoms.Clinical manifestations included,gastrointestinal bleeding,gastric ulceration with/without perforation,pancreatitis,and gastric outlet obstruction.Systemic review of the literature yielded 232 publications detailing symptomatic cases with only 20 studies describing ten or more patients.Single and multi-patient studies were combined to form a cohort of 934 symptomatic patients.The majority of patients presented with abdominal pain(67%)combined with one of the following clinical categories:(1)Dyspepsia,(n=445,48%);(2)Pancreatitis(n=260,28%);(3)Gastrointestinal bleeding(n=80,9%);and(4)Gastric outlet obstruction(n=80,9%).The majority of cases(n=832,90%)underwent surgical or endoscopic resection with 85%reporting resolution or improvement in their symptoms.CONCLUSION Heterotopic pancreas can cause significant clinical symptoms in the upper gastrointestinal tract.Better understanding and classification of this disease may result in more accurate identification and treatment of this malformation. | Michael T Le Compte Brandon Mason Keenan J Robbins Motoyo Yano Deyali Chatterjee Ryan C Fields Steven M Strasberg William G Hawkins | 2022 | World Journal of Gastroenterology2022，28，14： | 3 |
| 3 | Genetic determinants of altered virulence of Taiwanese foot-and-mouth disease virus显示文摘 | Beard C W Mason P W | 2000 | J Virol2000，74，： | 2 |
| 4 | Hepatitis B virus biology显示文摘 | Seeger C Mason WS | | Microbiology and Molecular Biology Reviews0，，： | 2 |
| 5 | T2NOM0 esophageal cancer 显示文摘 | Rice T W Mason D P Murthy S C | 2007 | J Thorac Cardiovasc Surg2007，133，： | 1 |
| 6 | Human CD4 (+) CD25 (+) thymoeytes and peripheral T cells have immune suppressive activity in virto 显示文摘 | Stephen LA Mottet C Mason D etal | 2001 | Eur J Immunol2001，31，： | 1 |
| 7 | Human immune responses to a novel Norwalk virus vaccine delivered in transgenic potatoes 显示文摘 | Mason H S Losonsky G | 2000 | J Infect Dis2000，182，： | 1 |
| 8 | Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C显示文摘 | Light Y Mason C | 1998 | Science1998，280，： | 1 |
| 9 | Design, synthesis, and anfiviral activity of 2'-deoxy- 2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication显示文摘 | CLARK L J HOLLECKER L MASON C J | 2005 | J Med Chem2005，48，17： | 1 |
| 10 | Forty-one near full-length HIV-1 sequences from Kenya reveal an epidemic of subtype A and A-containing recombinants显示文摘 | Dowling W E Kim B Mason C J | 2002 | AIDS2002，16，： | 1 |
| 11 | Enhanced electron injection in organic electroluminescence devices using an Al/LiF electrode 显示文摘 | Hung L S Tang C W Mason M G | 1997 | Appl Phys Lett1997，70，： | 1 |
| 12 | Baculoviral expression and characterization of rodent cathepsin S显示文摘 | Mason C S Lamers M B Henderson I M | 2001 | Protein Expression and Purication2001，23，： | 1 |
| 13 | Differentiation of beach , dune and aeolian flat environment by size analysis 显示文摘 | Mason C C Folk R L | 1958 | Journal of Sedimentary Petrology1958，28，： | 1 |
| 14 | Upper Echelons: The or- ganization as a Reflection of Its Top Managers 显示文摘 | Hambrick D C Mason P A | 1984 | A- cademy of Management Review1984，9，2： | 1 |
| 15 | The global framework for climate ser- vices显示文摘 | Hewitt C Mason S Walland D | 2012 | Nature Climate Change2012，2，12： | 1 |
| 16 | Sulfide controls on mercury speciation and the bioavailability in sediment pore waters显示文摘 | BENOIT J M GILMOUR C C MASON R P | 1999 | Environmental Science & Technology1999，33，： | 1 |
| 17 | Host plant constituents as oviposition stimulants for a generalist herbivore:Euro- pean corn borer 显示文摘 | Udayagiri S Mason C E | 1995 | Entomologia Experimentalis et Ap- plicata1995，76，1： | 1 |
| 18 | Chemical form of selenium in soybean lectin显示文摘 | Sathe S K Mason A C Rodibaugh R | 1992 | Journal of Agricultural and Food Chemistry1992，40，11： | 1 |
| 19 | Gastric bypass in obesity显示文摘 | Mason EE Ito C | 1967 | Surg Clin North Am1967，47，6： | 1 |
| 20 | Upper echelons: the organizationsas a reflection of its m anagers显示文摘 | HAMBRICK D C MASON P A | 1984 | Academy ofManagement Review-1984，9，2： | 1 |
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