|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Analysis of the postoperative hemostatic profile of colorectal cancer patients subjected to liver metastasis resection surgery显示文摘BACKGROUND Liver resection surgery has advanced greatly in recent years,and the adoption of fasttrack programs has yielded good results.Combination anesthesia (general anesthesia associated to epidural analgesia) is an anesthetic-analgesic strategy commonly used for the perioperative management of patients undergoing surgery of this kind,though there is controversy regarding the coagulation alterations it may cause and which can favor the development of spinal hematomas.AIM To study the postoperative course of liver resection surgery,an analysis was made of the outcomes of liver resection surgery due to colorectal cancer metastases in our centre in terms of morbiditymortality and hospital stay according to the anesthetic technique used (general vs combination anesthesia).METHODS A prospective study was made of 61 colorectal cancer patients undergoing surgery due to liver metastases under general and combination anesthesia between January 2014 and October 2015.The patient characteristics,intraoperative variables,postoperative complications,evolution of hemostatic parameters,and stay in intensive care and in hospital were analyzed.RESULTS A total of 61 patients were included in two homogeneous groups: general anesthesia (n = 30) and combination anesthesia (general anesthesia associated to epidural analgesia)(n = 31).All patients had normal coagulation values before surgery.The international normalized ratio (INR) in both the general and combination anesthesia groups reached maximum values at 2448 h (mean 1.37 and 1.45 vs 1.39 and 1.41,respectively),followed by a gradual decrease.There was less intraoperative bleeding in the combination anesthesia group (769 mL) than in the general anesthesia group (1200 mL)(P < 0.05).Of the 61 patients,38.8% in the general anesthesia group experienced some respiratory complication vs 6.6% in the combination anesthesia group (P < 0.001).The time to gastrointestinal tolerance was significantly correlated to the type of anesthesia,though not so the stay in critical care or the time to hospital discharge.CONCLUSION Epidural analgesia in liver resection surgery was seen to be safe,with good results in terms of pain control and respiratory complications,and with no associated increase in complications secondary to altered hemostasis. | Guillermo Perez Navarro Ana Maria Pascual Bellosta Sonia María Ortega Lucea Mario Serradilla Martín Jose Manuel Ramirez Rodriguez Javier Martinez Ubieto | 2019 | World Journal of Clinical Cases2019，7，17： | 4 |
| 2 | Capsule endoscopy capture rate: Has 4 frames-per-second any impact over 2frames-per-second?显示文摘AIM: To compare the current capsule and a new prototype at 2 and 4 frames-per-second, respectively, in terms of clinical and therapeutic impact. METHODS: One hundred patients with an indication for capsule endoscopy were included in the study. All procedures were performed with the new device(SB24). After an exhaustive evaluation of the SB24 videos, they were then converted to 'SB2-like' videos for their evaluation. Findings, frames per finding, and clinical and therapeutic impact derived from video visualization were analyzed. Kappa index for interobserver agreement and χ2 and Student's t tests for qualitative/quantitative variables, respectively, were used. Values of P under 0.05 were considered statistically significant.RESULTS: Eighty-nine out of 100 cases included in the study were ultimately included in the analysis. The SB24 videos detected the anatomical landmarks(Zline and duodenal papilla) and lesions in more patients than the 'SB2-like' videos. On the other hand, the SB24 videos detected more frames per landmark/lesion than the 'SB2-like' videos. However, these differences were not statistically significant(P > 0.05). Both clinical and therapeutic impacts were similar between SB24 and 'SB2-like' videos(K = 0.954). The time spent by readers was significantly higher for SB24 videos visualization(P < 0.05) than for 'SB2-like' videos when all images captured by the capsule were considered. However, these differences become non-significant if we only take into account small bowel images(P > 0.05).CONCLUSION: More frames-per-second detect more landmarks, lesions, and frames per landmark/lesion, but is time consuming and has a very low impact on clinical and therapeutic management. | Ignacio Fernandez-Urien Cristina Carretero Erika Borobio Ana Borda Emilio Estevez Sara Galter Begoa Gonzalez-Suarez Benito Gonzalez Marisol Lujan Jose Luis Martinez Vanessa Martínez Pedro Menchén Javier Navajas Vicente Pons Cesar Prieto Julio Valle | 2014 | World Journal of Gastroenterology2014，20，39： | 2 |
| 3 | Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome:A multicenter retrospective study显示文摘BACKGROUND Single-nucleotide polymorphisms(SNPs)of the serotonin type 3 receptor subunit(HTR3)genes have been associated with psychosomatic symptoms,but it is not clear whether these associations exist in irritable bowel syndrome(IBS).AIM To assess the association of HTR3 polymorphisms with depressive,anxiety,and somatization symptoms in individuals with IBS.METHODS In this retrospective study,623 participants with IBS were recruited from five specialty centers in Germany,Sweden,the United States,the United Kingdom,and Ireland.Depressive,anxiety,and somatization symptoms and sociodemographic characteristics were collected.Four functional SNPs—HTR3A c.-42C>T,HTR3B c.386A>C,HTR3C c.489C>A,and HTR3E c.*76G>A—were genotyped and analyzed using the dominant and recessive models.We also performed separate analyses for sex and IBS subtypes.SNP scores were calculated as the number of minor alleles of the SNPs above.The impact of HTR3C c.489C>A was tested by radioligand-binding and calcium influx assays.RESULTS Depressive and anxiety symptoms significantly worsened with increasing numbers of minor HTR3C c.489C>A alleles in the dominant model(F_(depressive)=7.475,P_(depressive)=0.006;F_(anxiety)=6.535,P_(anxiety)=0.011).A higher SNP score(range 0-6)was linked to a worsened depressive symptoms score(F=7.710,P-linear trend=0.006)in IBS.The potential relevance of the HTR3C SNP was corroborated,showing changes in the expression level of 5-HT3AC variant receptors.CONCLUSION We have provided the first evidence that HTR3C c.489C>A is involved in depressive and anxiety symptoms in individuals with IBS.The SNP score indicated that an increasing number of minor alleles is linked to the worsening of depressive symptoms in IBS. | Sabrina Berens Yuanjun Dong Nikola Fritz Jutta Walstab Mauro D'Amato Tenghao Zheng Verena Wahl Felix Boekstegers Justo Lorenzo Bermejo Cristina Martinez Stefanie Schmitteckert Egbert Clevers Felicitas Engel Annika Gauss Wolfgang Herzog Robin Spiller Miriam Goebel-Stengel Hubert Mönnikes Viola Andresen Frieling Thomas Jutta Keller Christian Pehl Christoph Stein-Thöringer Gerard Clarke Timothy G Dinan Eamonn M Quigley Gregory Sayuk Magnus Simrén Jonas Tesarz Gudrun Rappold Lukas van Oudenhove Rainer Schaefert Beate Niesler | 2022 | World Journal of Gastroenterology2022，28，21： | 2 |
| 4 | Eicosapentaenoic acid actions on adiposity and insulin resistance in control and high - fat - fed rats : Role of apoptosis, adiponectin and tumour necrosis factor - alpha 显示文摘 | Perez - Matute P Perez - Echarfi N Martinez JA | 2007 | Br J Nutr2007，97，2： | 1 |
| 5 | Food-web structure and network theory:The role of connectance and size显示文摘 | Dunne J A Williams R J Martinez N D | 2002 | Proceedings of the National Academy of Sciences2002，99，12： | 1 |
| 6 | qPCR for quantitative detection of tyramine-producing bacteria in dairy products显示文摘 | LADERO V MARTINEZ N MARTIN M C | 2010 | Food Research International2010，43，1： | 1 |
| 7 | Consensus conference: Treatment of type 2 diabetes in the elderly 显示文摘 | Martinez Velilla N Vilches Moraga A | 2013 | Med Clin (Bare)2013，，： | 1 |
| 8 | A power-efficient all-optical on-chip interconnect using wavelength-based oblivious routing 显示文摘 | N Kirman J F Martinez | 2010 | Acm Sigplan Notices2010，45，3： | 1 |
| 9 | Sprouty2 binds Grb2 at two different proline-rich regions,and the mechanism of ERK inhibition is independent of this interaction显示文摘 | Martinez N Garcia-Domingnez CA Domingo B | 2007 | Cell Signal2007，19，： | 1 |
| 10 | Effect of high hydrostatic pressure treatments on physicochemical properties, microbial quality and sensory attributes of beef carpaccio显示文摘 | Natalia Szerman Yanina Barrio Belén Schroeder Paula Martinez Ana María Sancho Claudio Sanow Sergio Ramón Vaudagna | 2011 | Procedia Food Science2011，，： | 1 |
| 11 | Sprouty-2 ~verexpression in C2C12 ceils confers myogenic differentiation properties in the presence of FGF2显示文摘 | DE ALVARO C MARTINEZ N ROJAS JM | 2005 | Mol Biol Ce112005，16，9： | 1 |
| 12 | The first case of invasive EEG monitoring for the surgical treatment of epilepsy : historical significance and context显示文摘 | Ahneida A N Martinez V Feindel W | 2005 | Epilepsia2005，46，7： | 1 |
| 13 | Solution structure of a conserved domain of antizyme:a protein regulator of polyamines显示文摘 | Hoffman D W Carroll D Martinez N | 2005 | Biochemistry2005，44，11： | 1 |
| 14 | A high performance single-phase rectifier with input power factor correction 显示文摘 | Martinez R Enjeti P N | 1996 | IEEE Transactions on Power Electronics1996，11，2： | 1 |
| 15 | Label-free DNA biosensors based on functionalized carbon nanotube field effect transistors显示文摘 | Martinez M T Tseng Y C Ormategui N | | 0，，02： | 1 |
| 16 | Characterization of aroma-impact compounds in yerba mate (llex paraguarien- sis) using GC - olfactometry and GC - MS显示文摘 | M6rquez V Martinez N Guerra M etal | 2013 | Food Re- search International2013，53，2： | 1 |
| 17 | miRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapy显示文摘 | MonteMoreno S Martinez N Sanehez-Espiridi6n B | 2011 | Blood2011，118，4： | 1 |
| 18 | Payments for Environmental Services in Watersheds : Insights from a Comparative Study of Three Cases in Central America 显示文摘 | Kosoy N Martinez - TunaM Muradian R | 2007 | Ecological Economics2007，，12： | 1 |
| 19 | Automatic thermographic and RGB texture of as-built BIM for energy rehabilitation purposes显示文摘 | Lagüela S Díaz-Vilari(n)o L Martinez J | | 0，，： | 1 |
| 20 | qPCR for quantitative detection of tyramine-producing bacteria in dairy products 显示文摘 | Ladero V Martinez N Martin MC Ferndndez M Alvarez MA | 2010 | Food Res Int2010，43，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员