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| 1 | Physiopathology of splanchnic vasodilation in portal hypertension显示文摘In liver cirrhosis, the circulatory hemodynamic alterations of portal hypertension signifi cantly contribute to many of the clinical manifestations of the disease. In the physiopathology of this vascular alteration, mesen- teric splanchnic vasodilation plays an essential role by initiating the hemodynamic process. Numerous studies performed in cirrhotic patients and animal models have shown that this splanchnic vasodilation is the result of an important increase in local and systemic vasodilators and the presence of a splanchnic vascular hyporesponsiveness to vasoconstrictors. Among the molecules and factors known to be potentially involved in this arterial vasodilation, nitric oxide seems to have a crucial role in the physiopathology of this vascular alteration. However, none of the wide variety of mediators can be described as solely responsible, since this phenomenon is multifactorial in origin. Moreover, angiogenesis and vascular remodeling processes alsoseem to play a role. Finally, the sympathetic nervous system is thought to be involved in the pathogenesis of the hyperdynamic circulation associated with portal hypertension, although the nature and extent of its role is not completely understood. In this review, we discuss the different mechanisms known to contribute to this complex phenomenon. | María Martell Mar Coll Nahia Ezkurdia Imma Raurell Joan Genescà | 2010 | World Journal of Hepatology2010，2，6： | 13 |
| 2 | The Synthesis of a New Macrocyclic Dinucleating Ligand,3,6,9,17,20,23-Hexaaza-29,30-Dihydroxy-13,27-Dimethyl-Tricyclo[23,3,1,1^(11,15)]Triaconta-1(28),11,13, 15(30),25,26-Hexaene显示文摘A new dinucleating 24-membered hexaazadiphenol macrocyclic ligand, 3,6,9,17,20, 23-hexaaza-29,30- dihydroxy-13,27-dimethyl-tricycl [23, 3, 1, 1 11,15] triaconta -1(28), 11,13,15(30),25, 26-hexaene, BDBPH, was synthesized by the NaBH4 reduction of the Schiff-base obtained from the [2+2] condensation between diethylenetriamine and diformyl -p-cresol. The structure was characterized by elemental analysis, 1HNMR and FAB-MS. The synthetic method was also discussed. | Guo Qiang SHANGGUAN Arthur E. MARTELL Zhong Ren ZHANG (Department of Chemistry, Jining Medical College, Jining 272013Department of Chemistry, Texas A&M University, College Station, Texas 77842 USA) | 2000 | Chinese Chemical Letters2000，11，7： | 2 |
| 3 | Distribution of the erm (B) gene, tetracycline resistance genes, and Tn1545 -- like transposons in macrolide- and lincosamide- resistant Enterococci from pigs and humans 显示文摘 | De Leener E Martel A Decostere A | 2004 | Microb Drug Resist2004，10，： | 1 |
| 4 | Glu- cocorticoid receptor mediated inhibition of interleukin-1 stimulated neutral metalloprotease synthesis in normal hu-man chondrocytes显示文摘 | DiBattista J A Martel Pelletier J Wosu L O | 1991 | J Clin Endocrinol Metab1991，72，2： | 1 |
| 5 | Endoscopic endonasal management of invasive skull base mucocele : report of two cases显示文摘 | ALFIERI A BONCOEUR - MARTEL MP MOUFID A | 2003 | Minim Invasive Neurosurg2003，46，6： | 1 |
| 6 | Efficacy and safety of famciclovir for treating mucocutaneous herpes simplex infection in HIV-infected individuals, collaborative famciclovir HIV study group 显示文摘 | Romanowski B Aoki FY Martel A Y | 2000 | AIDS2000，14，9： | 1 |
| 7 | Thermal behavior of Bombyx mori silk:evolution of crystalline parameters,molecular structure,and mechanical properties显示文摘 | Martel A Burghammer M Davies RJ | | 0，，11： | 1 |
| 8 | Evolution of chloramphenicol resistance,with emergence of cross-resistance to florfenicol,in bovine Salmonella Typhimurium strains implicates definitive phage type (DT) 104显示文摘 | ARCANGIOLI M A LEROY-SETRIN S MARTEL J L | 2000 | J Med Microbiol2000，49，： | 1 |
| 9 | Effects of temperature during early life history on embryonic and larval development and growth in haddock显示文摘 | Martell D J Kieffer J D Trippel E A | 2005 | Journal of Fish Biology2005，66，： | 1 |
| 10 | 查看详情显示文摘 | Nguyen T B Martel A Dhal R Dujardin G | | 0，，： | 1 |
| 11 | Los tumores de ia fosa cerebral posterior: voluminoso neurinoma del hipogloso con de- sarrollo juxtabulbo-protuberancial operacioncuracion 显示文摘 | De Martel T Subirana A Gnillaume J | 1933 | Ars Med1933，9，： | 1 |
| 12 | Dioxygen affinities of synthetic co- balt Schiff base complexes 显示文摘 | Chen D Martell A E | 1987 | Inorg Chem1987，26，： | 1 |
| 13 | Net- work Companies and Competitiveness: A Framework for Analysis 显示文摘 | LAKHAL S MARTEL A KETFANI O ORAL M | 1999 | European Journal of Operations Research1999，118，2： | 1 |
| 14 | Presence of macrolide resistance genes in streptococci and enterococci isolated from pigs and pork carcasses显示文摘 | Martel A Devriese LA Decostere A | 2003 | Int J Food Microbiol2003，84，1： | 1 |
| 15 | Solving multi-criteria scheduling flow shop problem through compromise programming and satisfaction functions显示文摘 | Allouche M A Aouni B Martel J M el al | 2009 | European Journal of Operational Research2009，192，2： | 1 |
| 16 | New synthetic cobalt schiff base complexes as oxygen carriers 显示文摘 | I Chen D Martell A E Sun Y | 1989 | Inorg Chem1989，28，： | 1 |
| 17 | Prevalence and Mechanism of Resistance against Macrilides and Lincosamides in Streptococcus suis Isolates显示文摘 | Martel A Baele M Devriese L A | 2001 | Vet Microbiol2001，83，： | 1 |
| 18 | 显示文摘 | FAUCHER S MARTEL A SHERRING A | 2004 | Clin Chem2004，50，： | 1 |
| 19 | Percutaneous radiofrequency ablation of benign bone tumors:osteoid osteoma,osteoblastoma,and chondroblastoma显示文摘 | Martel Villagrán J Bueno Horcajadas A Ortiz Cruz EJ | 2009 | Radiologia2009，51，6： | 1 |
| 20 | Novel chiral N4S2-and N6S3-donor macrocyclic ligands:synthesis,protonation constants,metal-ion binding and asymmetric catalysis in the Henry reaction显示文摘 | Gao J Martell A E | 2003 | Org Biomol Chem2003，1，15： | 1 |
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