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| 1 | Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome显示文摘Polycystic ovary syndrome(PCOS) is the most common endocrine disorder in reproductive-aged women. Women with PCOS frequently have metabolic complications including insulin resistance(IR), early diabetes, hypertension and dyslipidemia. Recent studies have demonstrated an association between PCOS and another metabolic complication: nonalcoholic fatty liver disease(NAFLD). NAFLD occurs as a result of abnormal lipid handling by the liver, which sensitizes the liver to injury and inflammation. It can progress to nonalcoholic steatohepatitis(NASH), which is characterized by hepatocyte injury and apoptosis. With time and further inflammation, NASH can progress to cirrhosis. Thus, given the young age at which NAFLD may occur in PCOS, these women may be at significant risk for progressive hepatic injury over the course of their lives. Many potential links between PCOS and NAFLD have been proposed, most notably IR and hyperandrogenemia. Further studies are needed to clarify the association between PCOS and NAFLD. In the interim, clinicians should be aware of this connection and consider screening for NAFLD in PCOS patients who have other metabolic risk factors. The optimal method of screening is unknown. However, measuring alanine aminotransferase and/or obtaining ultrasound on high-risk patients can be considered. First line treatment consists of lifestyle interventions and weight loss, with possible pharmacologic interventions in some cases. | Carly E Kelley Ann J Brown Anna Mae Diehl Tracy L Setji | 2014 | World Journal of Gastroenterology2014，20，39： | 11 |
| 2 | The prevalence and etiology of elevated aminotransferase levels in the United States显示文摘 | Jeanne M Clark Frederick L Brancati Anna Mae Diehl | 2003 | The American Journal of Gastroenterology2003，，5： | 2 |
| 3 | Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo显示文摘 | Brackman G Cos P Maes L | | 0，，06： | 1 |
| 4 | Health risk assessment of dioxin emissions from municipal waste incinerators: the Neerlandquarter (Wilrijk, Belgium)显示文摘 | J Nouwen C Cornelis R De Fré M Wevers P Viaene C Mensink J Patyn L Verschaeve R Hooghe A Maes M Collier G Schoeters R Van Cleuvenbergen P Geuzens | 2001 | Chemosphere2001，，4： | 1 |
| 5 | Anassessment of regression of left ventricular hypertrophy followingalcohol ablation of the interventricular septum in patients withhypertrophic cardiomyopathy with left ventricular outflow tractobstruction显示文摘 | DABROWSKI M CHOJNOWSKA L MAE K | 2012 | Kardiol Pol2012，70，8： | 1 |
| 6 | Automated model- based bias field correction of MR images of the brain 显示文摘 | Van L K Maes F Vandermeulen D | 1999 | IEEE Transactions of Medical Imaging1999，18，10： | 1 |
| 7 | Elevated serum interleukin-6 (IL-6) and IL-6 receptor concent rations in posttraumatic stress disorder following accidental manmade traumatic events显示文摘 | Maes M Lin AH Delmeire L | 1999 | Biol Psychiatry1999，45，7： | 1 |
| 8 | Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair 显示文摘 | Maes C Coenegrachts L Stockmans I | 2006 | J Clin Invest2006，116，5： | 1 |
| 9 | In vivo action of the anticoccidial diclazuril(clinacx) on the development stases of Eimeria tenella: a histological study显示文摘 | Maes L | 1988 | J Parasltol1988，74，6： | 1 |
| 10 | In vitro cytogenetic effects of 2 450 MHz waves on human peripheral blood lymphocytes 显示文摘 | Maes A Verschaeve L Arroyo A | 1993 | Bioelectromagnetics1993，14，6： | 1 |
| 11 | Qnorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo 显示文摘 | Brackman G Cos P Maes L | 2011 | Antimicrobial agents and chemotherapy2011，55，22： | 1 |
| 12 | Coumarins from Cnidium monnieri and their antiosteoporotic activity显示文摘 | Zhang Q Qin L He W Van Puyvelde L Maes D Adams A Zheng H De Kimpe N | 2007 | Planta Med2007，73，1： | 1 |
| 13 | Influence of reducing agem( CO,H2 ,and C2H4 ) and of I-I20 on NO, reduction on a Pt-Ba/AI203 catalyst 显示文摘 | Scholz C M L Maes B H W de Croon M H J M | 2007 | Applied Catalysis A: General2007，332，1： | 1 |
| 14 | Mi- gration dynamics of clupeoids in the Schelde estuary: A stable isotope approach 显示文摘 | Guelinckx J Maes J De Brabandere L | 2006 | Estuar Coast Shelf Sci2006，66，34： | 1 |
| 15 | Evaluation of 14 organic so- lvents and carriers for screening applications in zebrafish embryos and larvae 显示文摘 | Maes J Verlooy L Buenafe OE | 2012 | PLoS One2012，7，43： | 1 |
| 16 | The Role of Natural Organic Matter in the Migration Behaviour of Americium in the Boom Clay-Part Ⅰ: Migration Experiments 显示文摘 | Maes N Wang L Hicks T | 2006 | Physics and Chemistry of the Earth2006，31，： | 1 |
| 17 | In vivo action of the anticoccidial diclazuril(clinacx) on the development stags of Eimeria tenella:a histological study 显示文摘 | Maes L | 1988 | J Parasitol1988，74，6： | 1 |
| 18 | Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo显示文摘 | Brackman G Cos P Maes L | 2011 | Antimicrob Agents Chemother2011，55，6： | 1 |
| 19 | Multi-item single-level capacitated dynamic lot-sizing heuristics:a general review显示文摘 | Maes J Van Wassenhove L N | 1988 | Journal of Operational Research Society1988，39，11： | 1 |
| 20 | Determination ot lidocaine and its two 1' - desethylated metabolites in dog and horse plasma by high - per- formance liquid chromatography combined with electrospray ioni zation tandem mass spectrometry 显示文摘 | Maes A Weiland L | 2007 | J Chromatogr B Analyt Technol Biomed Life Sci2007，852，12： | 1 |
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