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| 1 | Study of ozone “weekend effect” in Shanghai显示文摘Analysis of observed ozone data in 2006 from five monitoring sites (Xujiahui, Chongming, Baoshan, Pudong, Jinshan) in Shanghai reveals that ozone (O_3) concentrations in Xujiahui are higher at week-ends than those on weekdays, despite the fact that emissions of ozone precursor substances, such as oxides of nitrogen (NOx), carbon monoxide (CO) and volatile organic compounds (VOCs) are lower at weekends than those on weekdays. The possible chemical cause of ozone 'weekend effect' is that NO_2/NO ratio increases at weekends by 25.61% compared with those on weekdays. In addition, because of an average 12.13% reduction in NOx (NO + NO_2) in the early morning (05:00-09:00) at weekends compared with that on weekdays, the ozone inhibition period ends 0.5 h earlier at weekends resulting in the longer duration of ozone accumulation and the higher ozone production rate. The rate of ozone production is a function of VOCs and NOx in the atmosphere. VOCs/NOx ratio in Xujiahui is 4.55 at weekends, and 4.37 on weekdays, belonging to the 'NOx-limited'. The increasing VOCs/NOx ratio at weekends leads to ozone enhancement from 73 ppbv to 80 ppbv, which are consistent with ozone 'weekend effect' in Xujiahui. Furthermore, combining with MICAPS cloud amount data, the fact that ozone 'weekend effect' in Xujiahui weakens gradually along with the increasing of cloud amount indicates that ozone photochemical production leads to ozone 'weekend effect' in Xujiahui of Shanghai. | TANG WenYuan1↑, ZHAO ChunSheng1, GENG FuHai1,2, PENG Li2, ZHOU GuangQiang2, GAO Wei2, XU JianMing2 & TIE XueXi2,3 1 Department of Atmospheric Science, School of Physics, Peking University, Beijing 100871, China 2 Atmospheric Chemistry Laboratory of Shanghai Meteorological Bureau, Shanghai 200030, China 3 Atmospheric Chemistry Division, NCAR, Boulder CO 80301, USA | 2008 | Science China Earth Sciences2008，51，9： | 23 |
| 2 | Elemental composition of aerosols collected in the glacier area on Nyainqêntanglha Range, Tibetan Plateau, during summer monsoon season显示文摘In order to investigate the elemental composition in atmospheric aerosols and its sources in the glacier area over the Tibetan Plateau (TP), seven totally suspended particle samples were collected continuously at the col of the Zhadang glacier (30°28′N,90°39′E,5800 m a.s.l.), Nyainqêntanglha Range, southern TP, from June to October 2006. Twenty-seven elements (Li, Be, B, Na, Mg, Al, K, Ca, Sc, Ti, V, Fe, Mn, Zn, Ga, As, Rb, Sr, Y, Cd, Cs, Ba, Tl, Pb, Bi, Th, U) were analyzed by Inductively Coupled Plasma Mass Spectrometry (ICP-MS). The result indicates that the concentrations of most elements (especially crustal elements) are lower than values at the Nam Co Station during the same period of 2005, and also much lower than other sites in the TP such as Wudaoliang and Waliguan. This suggests that elemental compositions of aerosols in the Zhadang glacier area may represent the background levels of the middle/upper troposphere over the TP. Crustal enrichment factors (EFs) reveal that several elements (e.g. B, Zn, As, Cd, Pb and Bi) may have anthropogenic sources. The southern TP is mainly influenced by the summer Indian monsoon during the sampling period. Backward air mass trajectory analysis suggests that air masses in the region may originate from South Asia. Therefore, anthropogenic pollutants from South Asia may be transported by the summer Indian monsoon to the region which clearly affects the atmospheric environment in the southern TP during the summer monsoon season. | LI ChaoLiu1,2, KANG ShiChang1,3 & CONG ZhiYuan1,2 1 Nam Co Monitoring and Research Station for Multisphere Interactions, Institute of Tibetan Plateau Research, CAS, Beijing 100085, China 2 Graduate University of Chinese Academy of Sciences, Beijing 100039, China 3 State Key Laboratory of Cryospheric Sciences, CAS, Lanzhou 730000, China | 2007 | Chinese Science Bulletin2007，52，24： | 18 |
| 3 | 有机硒可降低肉品的滴水损失显示文摘有机硒可降低肉品的滴水损失DonaldCoMahan著文杰摘译肖玉校禽肉的滴水损失(driplos)、猪肉的PSE肉,都是由细胞膜氧化破裂、细胞液外溢所致。滴水损失发生后,肉的外观变差,烹饪时肉变柴变干。本文简要介绍硒和维生素E对减少肉品滴水损失的作... | Donald Co Mahan 文杰 肖玉 | 1997 | 国外畜牧科技1997，24，2： | 14 |
| 4 | Tension and Thickness Control Strategy Analysis of Two Stands Reversible Cold Rolling Mill显示文摘In order to lucubrate the rolling characteristic of the two stands reversible cold rolling mill and establish the tension and thickness control strategy, the steady-state characteristic simulating program was established using the steady-state continuous rolling theory. The influences of each factor on exit thickness under different tension control methods were analyzed. The results show that, the influence of the entry stand gap on exit thickness is significant and it changes little with different tension control methods. As a result, the entry stand gap can be used as the main control method of exit thickness, whereas rolling speed of any stand and roll gap of the exit stand can be used to adjust the inter-stand tension. The results are beneficial for thickness and tension control of the two stands reversible cold rolling mill. | LIU Guang-ming1, DI Hong-shuang2, ZHOU Cun-long1, LI Hong-cui3, LIU Jiang3 (1. College of Materials Science and Engineering, Taiyuan University of Science and Technology, Taiyuan 030024, Shanxi, China 2. State Key Laboratory of Rolling and Automation, Northeastern University, Shenyang 110819, Liaoning, China 3. Cold Rolling Plant, Jinan Iron and Steel Group Co Ltd, Jinan 250101, Shandong, China) | 2012 | Journal of Iron and Steel Research(International)2012，19，10： | 12 |
| 5 | HCWCI/Carbon Steel Bimetal Liner by Liquid-Liquid Compound Lost Foam Casting显示文摘Impact, friction and corrosion from the grinding balls and the grinding medium during the mineral processing result in liner breakage. Liner, made from Hadfield steel or alloyed steel, could not have served in wet grinding environment for more than ten months. Composite liner, made from HCWCI (high Cr white cast iron) and carbon steel, has been developed successfully with liquid-liquid composing process based on LFC (lost foam casting). The microstructure of composite was analyzed with optical microscope, SEM (scanning electron microscope)/EDX energy-dispersive X-ray and XRD (X-ray diffraction). According to micrograph, the combination region of two metals was staggered like dogtooth, no mixtures occurred between two liquid metals, and its interface presented excellent metallurgical bonding state. The results of mechanical property test show that, the hardness of HRC, the fracture toughness, and the bending strength are more than 61, 16.5 J/cm2 and 1 600 MPa, respectively. Comparison between liners made from bimetal composite and alloyed steel has also been investigated in industrial hematite ball mill. The results of eight months test in wet grinding environment prove that the service life of bimetal composite liner is three times as long as that of one made from alloyed steel. | XIAO Xiao-feng1,2, YE Sheng-ping2, YIN Wei-xin3, XUE Qiong4 (1. School of Mechanical Engineering and Automation, Wuhan Textile University, Wuhan 430073, Hubei, China 2. State Key Laboratory of Material Processing and Die and Mould Technology, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China 3. Wuhan Zhike Abrasive-Resistant Material Science and Technology Development Co Ltd, Wuhan 430073, Hubei, China 4. College of Science, Wuhan University of Technology, Wuhan 430079, Hubei, China) | 2012 | Journal of Iron and Steel Research(International)2012，19，10： | 11 |
| 6 | Dome Combustion Hot Blast Stove for Huge Blast Furnace显示文摘In Shougang Jingtang 5 500m 3 huge blast furnace ( BF ) design , dome combustion hot blast stove ( DCHBS ) technology is developed.DCHBS process is optimized and integrated , and reasonable hot blast stove ( HBS ) technical parameters are determined.Mathematic model is established and adopted by computational fluid dynamics ( CFD ) .The transmission theory is studied for hot blast stove combustion and gas flow , and distribution results of HBS velocity field , CO density field and temperature field are achieved.Physical test model and hot trail unit are established , and the numeral calculation result is verified through test and investigation.3-D simulation design is adopted.HBS process flow and process layout are optimized and designed.Combustion air two-stage high temperature preheating technology is designed and developed.Two sets of small size DCHBSs are adopted to preheat the combustion air to 520-600℃.With the precondition of BF gas combustion , the hot blast stove dome temperature can exceed 1 420 ℃. According to DCHBS technical features , reasonable refractory structure is designed.Effective technical measures are adopted to prevent hot blast stove shell intercrystalline stress corrosion.Hot blast stove hot pipe and lining system are optimized and designed.After blowing in , the blast temperature keeps increasing , and the monthly average blast temperature reaches 1 300℃ when burning single BF gas. | ZHANG Fu-ming , MAO Qing-wu , MEI Cong-hua , LI Xin , HU Zu-rui ( Beijing Shougang International Engineering Technology Co Ltd , Beijing 100043 , China ) | 2012 | Journal of Iron and Steel Research(International)2012，19，9： | 11 |
| 7 | Climate Changes in the 21st Century over the Asia-Pacific Region Simulated by the NCAR CSM and PCM显示文摘The Climate System Model (CSM) and the Parallel Climate Model (PCM), two coupled global climate models without flux adjustments recently developed at NCAR, were used to simulate the 20th century climate using historical greenhouse gas and sulfate aerosol forcing. These simulations were extended through the 21st century under two newly developed scenarios, a business-as-usual case (BAU, CO2≈710 ppmv in 2100) and a CO2 stabilization case (STA550, CO2≈540 ppmv in 2100). The simulated changes in temperature, precipitation, and soil moisture over the Asia-Pacific region (10°-60°N, 55°-155°) are analyzed, with a focus on the East Asian summer monsoon rainfall and climate changes over the upper reaches of the Yangtze River. Under the BAU scenario, both the models produce surface warming of about 3-5℃ in winter and 2-3℃ in summer over most Asia. Under the STA550 scenario, the warming is reduced by 0.5-1.0℃ in winter and by 0.5℃ in summer. The warming is fairly uniform at the low latitudes and does not induce significant changes in the zonal mean Hadley circulation over the Asia-Pacific do- main While the regional precipitation changes from single CSM integrations are noisy, the PCM ensemble mean precipitation shows 10%-30% increases north of ~ 30°N and~10% decreases south of ~ 30°N over the Asia-Pacific region in winter and 10%-20% increases in summer precipitation over most of the region. Soil moisture changes are small over most Asia The CSM single simulation suggests a 30% increase in river runoff into the Three Gorges Dam, but the PCM ensemble simulations show small changes in the | Aiguo Dai, G.A. Meehl, W.M. Washington, and T.M.L. Wigley National Center for Atmospheric Research P.O. Box 3000, Boulder, CO 80307 ) Email: adai@ ucar. edu The National Center for Atmospheric Research is sponsored by the U S National Science Foundation. | 2001 | Advances in Atmospheric Sciences2001，18，5： | 9 |
| 8 | A one-dimensional heat transfer model of the Antarctic Ice Sheet and modeling of snow temperatures at Dome A, the summit of Antarctic Plateau显示文摘A vertical one-dimensional numerical model for heat transferring within the near-surface snow layer of the Antarctic Ice Sheet was developed based on simplified parameterizations of associated physical processes for the atmosphere, radiation, and snow/ice systems. Using the meteorological data of an automatic weather station (AWS) at Dome A (80°22′S, 70°22′E), we applied the model to simulate the seasonal temperature variation within a depth of 20 m. Comparison of modeled results with observed snow temperatures at 4 measurement depths (0.1, 1, 3, 10 m) shows good agreement and consistent seasonal variations. The model results reveal the vertical temperature structure within the near-surface snow layer and its seasonal variance with more details than those by limited measurements. Analyses on the model outputs of the surface energy fluxes show that: 1) the surface energy balance at Dome A is characterized by the compensation between negative net radiation and the positive sensible fluxes, and 2) the sensible heat is on average transported from the atmosphere to the snow, and has an evident increase in spring. The results are considered well representative for the highest interior Antarctic Plateau. | CHEN BaiLian1,3, ZHANG RenHe2, SUN ShuFen1, BIAN LinGen2, XIAO CunDe4,2 & ZHANG TingJun5 1 Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China 2 Chinese Academy of Meteorological Sciences, Beijing 100081, China 3 Graduate University of Chinese Academy of Sciences, Beijing 100049, China 4 Cold and Arid Regions Environmental and Engineering Research Institute, Chinese Academy of Sciences, Lanzhou 730000, China 5 The National Snow and Ice Data Center, University of Colorado, Boulder, CO 80309-0449, USA | 2010 | Science China Earth Sciences2010，53，5： | 7 |
| 9 | Effects of glutamine supplementation on gut barrier,glutathione content and acute phase response in malnourished rats during inflammatory shock显示文摘AIM: To evaluate the effect of glutamine on intestinal mucosa integrity,glutathione stores and acute phase response in protein-depleted rats during an inflammatory shock. METHODS: Plasma acute phase proteins (APP),jejunal APP mRNA levels,liver and jejunal glutathione concentrations were measured before and one,three and seven days after turpentine injection in 4 groups of control,protein-restricted,protein-restricted rats supplemented with glutamine or protein powder. Bacterial translocation in mesenteric lymph nodes and intestinal morphology were also assessed. RESULTS: Protein deprivation and turpentine injection significantly reduced jejunal villus height,and crypt depths. Mucosal glutathione concentration significantly decreased in protein-restricted rats. Before turpentine oil,glutamine supplementation restored villus heights and glutathione concentration (3.24 ± 1.05 vs 1.72 ± 0.46 μmol/g tissue,P < 0.05) in the jejunum,whereas in the liver glutathione remained low. Glutamine markedly increased jejunal α1-acid glycoprotein mRNA level after turpentine oil but did not affect its plasma concentration. Bacterial translocation in protein-restricted rats was not prevented by glutamine or protein powder supplementation. CONCLUSION: Glutamine restored gut glutathione stores and villus heights in malnourished rats but had no preventive effect on bacterial translocation in our model. | Liliana Belmonte Mose Co■ffier Florence Le Pessot Olga Miralles-Barrachina Martine Hiron Antony Leplingard Jean-Franois Lemeland Bernadette Hecketsweiler Maryvonne Daveau Philippe Ducrotté Pierre Déchelotte | 2007 | World Journal of Gastroenterology2007，13，20： | 6 |
| 10 | Reduction Behavior of Sinter Based on Top Gas Recycling-Oxygen Blast Furnace显示文摘In order to explore the behavior laws of sinter reduction in TGR-OBF ( top gas recycling-oxygen blast furnace ), reduction experiments of sinter have been conducted by thermal balance mass loss method with different atmospheres , temperatures and volume flows.The changes of RI ( reduction degree of Fe 2 O 3 ), RI′ ( reduction rate of Fe 2 O 3 ) and r ( reduction degree of FeO ) have been examined.The results show that the reduction of sinter was significantly improved under TGR-OBF atmosphere , and the RIand r were measured up to 98.2%and 97.8%at 900℃ respectively.With increasing of the reduction temperature , the reduction of sinter speeded up greatly , and the reduction time-duration shortened from 117min at 900 ℃ to 63min at 1 100 ℃.Moreover , the reduction of sinter enhanced with increasing of the reductive gas flow.When the flow increased from 10to 15L / min , the initial reduction rate of sinter increased from 2.47% / min to 3.73% / min.While increasing H2and CO contents in the reductive atmosphere , the reduction of sinter was promoted.Besides , H 2 influenced more evidently than CO to the reduction of sinter , especially in the later stage of the reduction process , for instance , the reduction of wustite will be improved enormously when increasing the H2content in the reductive atmosphere. | LAN Rong-zong 1 , 2 , WANG Jing-song 1 , HAN Yi-hua 1 , SHE Xue-feng 1 , WANG Lin-tao 1 , XUE Qing-guo 1 ( 1.State Key Laboratory of Advanced Metallurgy , University of Science and Technology Beijing , Beijing 100083 , China 2.China Railway Materials Xiamen Steel Co Ltd , Xiamen 361008 , Fujian , China ) | 2012 | Journal of Iron and Steel Research(International)2012，19，9： | 6 |
| 11 | 血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI. | Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A | 2014 | 中华神经外科疾病研究杂志2014，13，3： | 6 |
| 12 | Overview:Development of Clean Steel Production at Baosteel显示文摘The development of clean steel technology at Baosteel can be dated back to the first production of IF steels and pipeline steels in the early 1990s.Now the technology has gradually covered nearly the whole range of products.This progressive development is introduced in the overview including the levels of cleanliness for some steel grades at Baosteel.The technologies at different processes for the production of clean steel and the removal of some impurity elements in molten steel are also discussed.Suggestions are given on the future research and development of clean steel technology at Baosteel in the aim to keep a sustainable development,which should focus on the basic research,inclusion control and making efficient use of inclusions,as well as stable and reliable low-cost manufacturing technology,removal of harmful residual elements,and the expanding of the technology to stainless steels and special steels. | HUANG Zong-ze,ZHENG Yi-yu,JIANG Xiao-fang,CUI Jian(Baoshan Iron and Steel Co Ltd.Shanghai 201900,China) | 2011 | Journal of Iron and Steel Research(International)2011，18，S2： | 5 |
| 13 | A cross-sectional study on compliance with topical glaucoma medication and its associated socioeconomic burden for a Chinese population显示文摘AIM: To estimate the overall drug compliance for local Chinese glaucoma patients on long-term topical treatment.METHODS: This was a retrospective cross-sectional study.Fifty-seven primary glaucoma patients from the subspecialty clinic of a publicly-funded tertiary care hospital in Hong Kong completed a questionnaire on compliance with topical glaucoma medication,attitude towards glaucoma and therapy and vision related quality of life.Noncompliance was defined as reporting missing more than or equal to 10% of the prescribed topical glaucoma medication during the 2wk immediately prior to the consultation.Relationships between noncompliance and demographics,attitude,disease and treatment status was studied.Cost was estimated with quality of life and direct medical cost involved with noncompliance.Multivariable logistic regression on noncompliance was performed on selected factors.RESULTS: Compliance was calculated as 75%(95% CI: 64%-87%) among 57 subjects(mean age 69 y,female 51%).No statistical significant relationship was established between noncompliance and any single factors or outcomes.Age(P=0.048) and forgetfulness(P=0.064) were found to be marginally significant predictive factors on noncompliance in multivariable logistic regression.Noncompliance might be related(P=0.130) to poorer self-rated vision-associated quality of life.The societal cost of noncompliance was estimated to be over 2510 life-years and US$ 3.7 million territory-wide.CONCLUSION: The compliance of Chinese glaucoma patients in Hong Kong is comparable to other parts in the world,and carries detrimental impacts on individual and societal levels.Age and forgetfulness are two possible independent predictors for noncompliance. | Man-Hin Lui Jason Chun Ho Lam Yi Lee Kwong Tak Siu Wong Pak Long Cheung Sherri Shun Yan Lai Pak Lun Yuen Wai Yiu Lam Ho Yan Chan Yiu Fai Wong Jimmy Shiu Ming Lai Kendrick Co Shih | 2017 | International Journal of Ophthalmology(English edition)2017，10，2： | 5 |
| 14 | Deformation Uniformity of Cold-Rolled Q235 Steel Rebar by FEM in Bending and Rolling Processes显示文摘An analytic model based on ANSYS/LS-DYNA has been developed on the cold rolling process for Q235 steel rebar with 12 mm in diameter. The elastic-plastic finite element method (FEM) and the cold deformation resistance model of Q235 steel were adopted in this model. Deformation uniformity of the final product has been analyzed using this model. The results indicate that the uniformity of the final product is obtained only as the centerline of the bending rolls is vertical to the centerline of the driven roll and parallel to the centerline of the drive roll in the whole rolling process. Besides, the number of the bending rolls must even realize the continuous bending and reverse bending process. Also, the number of the bending rolls must match the deformation degree of the workpiece in the cold rolling process. The validity of this finite element model was verified by the size and distribution of grains from the billet to the rebar in a practical cold rolling process. | SUI Feng-li1, CHEN Qi-wei1, ZHU Guo-hui1, LIU Bao-dong2 (1. Anhui Key Laboratory of Materials and Processing, School of Materials Science and Engineering, Anhui University of Technology, Maanshan 243002, Anhui, China 2. Dongyang Steel Making Co Ltd, Shenyang 110026, Liaoning, China) | 2012 | Journal of Iron and Steel Research(International)2012，19，8： | 4 |
| 15 | Excellent Heat Affected Zone Toughness Technology Improved by Use of Strong Deoxidizers显示文摘Excellent Heat Affected Zone Toughness Technology Improved by use of Strong Deoxidizers (ETISD Technology) has been developed by Baosteel. When deoxidation of molten steel is conducted at the precisely controlled oxygen concentrations, the formation of the micro-meter inclusions and the nano-meter precipitates in the steel plate can be effectively controlled. During the welding process with high-heat input, the formation of acicular ferrite can be selectively promoted with the aid of micro-meter inclusions; the growth of γ grain can also be selectively restrained by the pinning effect of nano-meter precipitates. After welding with high-heat input of 400 kJ/cm, excellent heat affected zone toughness can be obtained for the steel plates with both of the above microstructures, and the average absorbed energy is greater than 200 J for V notch Charpy impact test at -20℃ . | YANG Jian, ZHU Kai, WANG Rui-zhi, SHEN Jian-guo (Metallurgical Process Department, Research Institute, Baoshan Iron and Steel Co Ltd, Shanghai 201900, China) | 2011 | Journal of Iron and Steel Research(International)2011，18，S2： | 4 |
| 16 | 2,4,6-trinitrobenzene sulfonic acid-induced chronic colitis with fibrosis and modulation of TGF-β1 signaling显示文摘AIM:To investigate whether targeting proteasome might reverse intestinal fibrosis in rats.METHODS:Chronic colitis was induced in rats by repeated administration of increasing dose of2,4,6-trinitrobenzene sulfonic acid(TNBS,15,30,45,60,60,60 mg)by rectal injection for 6 wk(from day0 to day 35),while control rats received the vehicle.TNBS+bortezomib(BTZ)rats received intraperitoneal injections of BTZ twice weekly(from day 37 to day44)at a dose of 25 mg/kg,whereas the control and TNBS groups received the same amount of the vehicle.Histologic scoring of inflammation and fibrosis was performed.Colonic production of transforming growth factor(TGF)-βwas measured by ELISA.Colon fibrosisrelated proteins such as phospho-p38,phosphoSMAD2/3,Akt and peroxisome proliferator activated receptorγ(PPARγ)were studied by western blot.Expression of the tight junction proteins,occludin and claudin-1,were assessed by Western blot.Colon proteasome activities(chymotrypsin-like and trypsinlike activities)were assessed.RESULTS:TNBS-treated rats had a higher colon weight/length ratio compared to control rats(P<0.01).Furthermore,fibrosis and inflammation scores were higher in TNBS-treated rats compared to control rats(P<0.01 for both).Colonic production of TGF-βproduction tended to be higher in TNBS-treated rats(P<0.06).Fibrosis-related proteins such as phospho-p38,phospho-SMAD2/3,and PPARγwere significantly higher in TNBS-treated rats compared to control rats(all P<0.05).TNBS rats had a higher expression of Akt compared to control rats(P<0.01).Tight junction proteins were modified by repeated TNBS challenge:colon occludin expression rose significantly(P<0.01),whereas claudin-1 expression fell(P<0.01).Bortezomib inhibition significantly decreased chymotrypsin-like activity(P<0.05),but had no significant effect on trypsin-like activity(P>0.05).In contrast,bortezomib had no effect on other studied parameters such as fibrosis score,TGF-βsignaling,or tight junction expression(P>0.05 for all).CONCLUSION:Rats with TNBS-induced chronic colitis exhibited colon fibrosis associated with higher TGF-βsignaling.Proteasome inhibition by bortezomib had no effect on fibrosis in our experimental conditions. | Emilien Loeuillard Julien Bertrand Anni Herranen Chloé Melchior Charlène Guérin Mo?se Co?ffier Moutaz Aziz Pierre Déchelotte Guillaume Savoye Rachel Marion-Letellier | 2014 | World Journal of Gastroenterology2014，20，48： | 4 |
| 17 | Overlap syndrome consisting of PSC-AIH with concomitant presence of a membranous glomerulonephritis and ulcerative colitis显示文摘The association of primary sclerosing cholangitis(PSC)and autoimmune hepatitis(AIH)is known as an overlap syndrome(OS).OS can also be described in the setting of concomitant presence of AIH and PSC.These diseases can in some cases be associated with ulcerative colitis.In this case report we describe,to our knowledge,the first case in the literature of a young Caucasian male suffering from ulcerative colitis and an overlap syndrome consisting of an association betweenPSC-AIH,with the concomitant presence of a membranous glomerulonephritis. | Odile Warling Christophe Bovy Carla Combra Timothée Noterdaeme Jean Delwaide Edouard Louis | 2014 | World Journal of Gastroenterology2014，20，16： | 4 |
| 18 | 门诊烧伤的预防与治疗显示文摘大多数烧伤可由初级保健医生在门诊实施治疗。加强预防可使烧伤发生率明显下降,特别对儿童而言。与其他创伤管理相似,烧伤管理包括初级和次级评估。处理浅度烧伤可采用药液、蜂蜜、芦荟或抗生素软膏局部用药。部分皮层烧伤局部用抗菌药物或吸收性封闭敷料有助于减少疼痛、促进愈合和防止创面干燥。 | Emillia CO Lloyd Blake C Rodgers 周淑新(译) 葛军(译) | 2013 | 中国全科医学2013，16，9： | 3 |
| 19 | Chemistry Design of B-Containing Ultra-Heavy Plate Steels Aided by Thermo-Calc Calculation显示文摘Effect of N-bonding elements on dissolution and precipitation of B in micro B-treated ultra-heavy plate steels has been investigated,utilizing Thermo-Calc thermo-dynamic software and experimental test.The calculation results show that Titanium or excessive Aluminum content is effective to bond Nitrogen,preventing BN from forming and thus keeping boron in solid solution in austenite,while Vanadium is not.The experiment has also revealed that slight amount of solution Boron by addition of Ti or a little excessive Aluminum is helpful to improve hardenability of the steels. | PAN Tao 1,WANG Xiao-yong 1,WANG Hua 2,LI Yun 2,SU Hang 1,YANG Cai-fu 1 (1.Division of structural materials,Central Iron and Steel Research Institute,Beijing 100081,China 2.Anshan Iron and Steel Co Ltd,Anshan 114001,Liaoning,China) | 2011 | Journal of Iron and Steel Research(International)2011，18，S1： | 3 |
| 20 | National Food Contamination Monitoring Programmes-Levels of Mercury, Lead and Cadmium in Chinese Foods显示文摘Six hundred and thirty-four food samples of six kinds were collected from Beijing,Shanghai, Jiangsu, Sichuan, Jilin and Guangdong areas, China and Hg, Pb, Cd contents were determined. The results showed that their levels in the Chinese foods were low; their levels in meat, egg, milk and fish were generally below the national hygienic standard. The average daily dietary intake of Hg, Pb, Cd were 7.25 μg, 103.77μg and 30.72 μg respectively and they were all less than the ADI established by | YANG HUI-FEN LUO XUE-YUN SHEN WEN ZHOU ZHONG-FU JIN CHUANG-YU YU FENGC AND LIANG CHUN-SUI(Institute of Food Safety Control and Inspection, Ministry of Public Health, 7 Pan Jia Yuan, Beijing 100021, China Shanghai Municipal Institute of Food Safety Co | 1994 | Biomedical and Environmental Sciences1994，7，4： | 3 |
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