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| 1 | Prognostic criteria for postoperative mortality in 170 patients undergoing major right hepatectomy显示文摘BACKGROUND: Postoperative hepatic failure is a dreadful complication after major hepatectomy and carries high morbidity and mortality rates. In this study, we assessed the accuracy of the 50/50 criteria (bilirubin >2.9 mg/dL and international normalized ratio >1.7 on postoperative day 5) and the Mullen criteria (bilirubin peak >7 mg/dL on postoperative days 1-7) in predicting death from hepatic failure in patients undergoing right hepatectomy only. In addition, we identified prognostic factors linked to intra-hospital morbidity and mortality in these patients. METHODS: One hundred seventy consecutive patients underwent major right hepatectomy at a tertiary medical center from 2000 to 2008. Nineteen (11.2%) patients suffered from liver cirrhosis. Univariate and multivariate analyses were performed to identify predictors of intra-hospital mortality, morbidity and death from hepatic failure. RESULTS: The intra-hospital mortality was 6.5% (11/170). Of the six patients who died from hepatic failure, one was positive for the 50/50 criteria, but all six patients were positive for the Mullen criteria. Multivariate analysis showed that male gender, hepatitis C (HCV), hepatocellular carcinoma, postoperative bilirubin >7 mg/dL and ALT<188 U/L on postoperative day 1 were predictive of death from hepatic failure in the postoperative period. Age >65 years, HCV, reoperation, andrenal failure were significant predictors of overall intra-hospital mortality on multivariate analysis. CONCLUSIONS: The Mullen criteria were more accurate than the 50/50 criteria in predicting death from hepatic failure in patients undergoing right hepatectomy. A bilirubin peak >7 mg/dL in the postoperative period, HCV positivity, hepatocellular carcinoma, and an ALT level <188 U/L on postoperative day 1 were associated with death from hepatic failure in our patient population. | Filippo Filicori Xavier M Keutgen Matteo Zanello Giorgio Ercolani Salomone Di Saverio Federico Sacchetti Antonio Daniele Pinna Gian Luca Grazi | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，5： | 2 |
| 2 | Serotonin modula- tion of the basal ganglia circuitry: therapeutic implication for Parkinson's disease and other motor disorders 显示文摘 | Di Matteo V Pierucci M Esposito E | 2008 | Prog Brain Res2008，172，： | 1 |
| 3 | Espresso coffee (EC) by POD : Study of thermal profile during extraction process and influence of water temperature on chemical-physical and sensorial properties 显示文摘 | D Albanese M Di Matteo M Poiana | 2009 | Food Research International2009，44，： | 1 |
| 4 | Biochemical evidence that tire atypical antipsychotic drags dozapine and rispenlone block 5-HT (2C) receptors in vivo显示文摘 | Di Matteo V Cacchio M Di Giulio C | 2002 | Phannacol Biochem Behav2002，71，4： | 1 |
| 5 | Intake of tomato-en- riched diet protects from 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons 显示文摘 | di Matteo V Pierucci M Di Giovanni G | 2009 | J Neural Transmission2009，73，： | 1 |
| 6 | A cost-of-illness study of spina bifida in Italy显示文摘 | Colombo GL Di Matteo S Vinci M | 2013 | Clinicoecon Outcomes Res2013，5，3： | 1 |
| 7 | The pathogenesis of endometrial polyps:a systematic semi-quantitative review显示文摘 | Indraccolo U Di Iorio R Matteo M | 2013 | Eur J Gynaecol Oncol2013，34，1： | 1 |
| 8 | Interactions with single-stranded and double-stranded DNA-binding factors and alternative promoter conformation upon transcriptional activation of the HtJg-a/RanBP1 and HtJg-c genes显示文摘 | Di Matteo G Salerno M Guarguaglini G | 1998 | J Biol Chem1998，273，： | 1 |
| 9 | Effect of acute administration of hypericum perforatum-CO2 extract on dopamine and serotonin release in the rat central nervous system显示文摘 | Di Matteo V Di Giovanni G Di Mascio M | 2000 | Pharmacopsychiatry2000，33，： | 1 |
| 10 | Intake of tomato-enriched diet protects from 6 - hydroxydopamine - induceddegeneration of rat nigral dopaminergic neurons 显示文摘 | Matteo V Pierucci M Di Giovanni G | 2009 | Journal ofNeural Transmission2009，73，： | 1 |
| 11 | Short-term efficacy to conventional blind injection versus ultrasound-guided injection of local corticosteroids in tenosynovitis in patients with inflammatory chronic arthritis:a randomized comparative study显示文摘 | Gutierrez M Di Matteo A Rosemffet M | 2016 | Joint Bone Spine2016，83，2： | 1 |
| 12 | The Pathogenesis ofendometrial Polyps:a systematic semi-quantitative review 显示文摘 | Indraccolo U Di Iorio R Matteo M | 2013 | Euro Pean journal2013，34，1： | 1 |
| 13 | Intracytoplasmic injection of morphologically selected spermatozoa (IMSI) improves outcome after assisted reproduction by deselecting physiologically poor quality spermatozoa 显示文摘 | WILDING M COPPOLA G DI MATTEO L | 2010 | J Assist Reprod Genet2010，，： | 1 |
| 14 | Morphologic observations on respiratory tracts of chickens after hatchery infectious bronchitis vaccination and formaldehyde fumigation 显示文摘 | Di Matteo A M Sonez M C Plano C M | 2000 | Avian Dis2000，44，3： | 1 |
| 15 | Effect of acute administration of hypericum perforaturn - CO2 extracton dopamine and serotonin release in the rat central system 显示文摘 | Di Matteo V Di Giovanni G Di Mascio M | | Pharmacopsychiatry0，33，1： | 1 |
| 16 | Loss of caveolin‐1 in prostate cancer stroma correlates with reduced relapse‐free survival and is functionally relevant to tumour progression显示文摘 | Gustavo Ayala Matteo Morello Anna Frolov Sungyong You Rile Li Fabiana Rosati Gianluca Bartolucci Giovanna Danza Rosalyn M Adam Timothy C Thompson Michael P Lisanti Michael R Freeman Dolores Di Vizio | 2013 | Pathol2013，，1： | 1 |
| 17 | Role of serotonin(2C) receptors in the control of brain dopaminergic function 显示文摘 | Di Matteo V Caeehlo M Di Giulio C | 2002 | Phannaeol Biochem Behav2002，71，4： | 1 |
| 18 | Intraeytoplasmic injection of morphologically selected spermatozoa (IMSI) improves outcome after assisted reproduction by deseleeting physiologically poor quality spermatozoa显示文摘 | Wilding M Coppola G di Matteo L | 2011 | J Assist Reprod Genet2011，28，： | 1 |
| 19 | Dide- Botcazo syndrome due to bilateral occlusion of posterior cerebral artery 显示文摘 | Cappellari M Tomelleri G Di Matteo A | 2010 | Neurol Sci2010，31，1： | 1 |
| 20 | Mitochondrial aggregation patterns and activity in human oocytes and preimplantation embryos显示文摘 | Dale B Marino M di Matteo L Alviggi C Pisaturo ML | 2001 | Hum Reprod2001，16，5： | 1 |
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