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| 1 | Postarthroscopy analgesiawith intra articular bupivacaine/morphine : a randomized clinical trial显示文摘 | Allen GC St Amand MA Lui AC | 1993 | Anesthesiology1993，79，3： | 1 |
| 2 | Complications and outcomes of pandemic 2009 Influenza A (H1N1) virus infection in hospitalized adults:how do they differ from those in seasonal influenza显示文摘 | Lee N Chan PK Lui GC | | 0，，12： | 1 |
| 3 | Postarthroscopy analgesia with intraarticular bupivacaine/morphine显示文摘 | Allen GC St Amand MA Lui AC | 1993 | Anesthesiology1993，79，3： | 1 |
| 4 | Multiplex PCR assay for identification of Corynebacterium pseudotuberculosis from pure cultures and for rapid detection of this pathogen in clinical samples显示文摘 | Luis GC Pacheco RR Castro TL | 2007 | J Med Microbiol2007，19，10： | 1 |
| 5 | Evaluation of a rapid strip and apartiele agglutination tests for syphilis diagnosis显示文摘 | Luis JF Felipe US Santa GC | 2007 | Diag Microbiol Infect Dis2007，59，： | 1 |
| 6 | Single port thorascopic surgery using the SILS tool as a novel method in the surgical treatment of pneumothorax 显示文摘 | Orlando GC Luis BG Esperanza SG | 2010 | Arch Bronconeumol2010，48，8： | 1 |
| 7 | Evaluation of a rapid strip and particle agglutination tests for syphilis diagnosis 显示文摘 | Luis JF Felipe US Santa GC | 2007 | Diag Microbiol Infect Dis2007，59，： | 1 |
| 8 | Gradualism in Acacia dealba- ta Link invasion: Impact on soil chemistry and microbial com- munity over a chronological sequence 显示文摘 | Pablo SA Alejandra GC Luis G | 2015 | Soil Biol Biochem2015，80，1： | 1 |
| 9 | Genetic inactivation of Par4 results in hyperactivation of NF - κB and impairment of JNK and p38 显示文摘 | Isabel GC Maria JL Luis MC | 2003 | EMBO Reports2003，4，3： | 1 |
| 10 | Postarthroscopy analgesia with intra articular bupivacaine/morphine:a randomized clinical trial显示文摘 | Allen GC St Amand MA Lui AC | | 0，，03： | 1 |
| 11 | Evaluation of a rapid strip and a particle agglutination tests for syphilis diagnosis显示文摘 | Luis JF Felipe US Santa GC | 2007 | Diagnostic Micro-biology and Infectious Disease2007，59，： | 1 |
| 12 | Viral clearance and inflammatory response patterns in adults hospitalized for pandemic2009influenza A(H1N1)virus pneumonia显示文摘 | Lee N Chan PK Wong CK Wong KT Choi KW Joynt GM Lam P Chan MC Wong BC Lui GC Sin WW Wong RY Lam WY Yeung AC Leung TF So HY Yu AW Sung JJ Hui DS | 2011 | Antivir Ther2011，16，2： | 1 |
| 13 | Cytokine response patterns in severe pandemic2009H1N1and seasonal influenza among hospitalized adults显示文摘 | Lee N Wong CK Chan PK Chan MC Wong RY Lun SW Ngai KL Lui GC Wong BC Lee SK Choi KW Hui DS | 2011 | PLoS One2011，6，26： | 1 |
| 14 | Prospective application of a bleeding and ischemic risks-adjusted antithrombotic protocol in elderly patients revascularized with everolimus-eluting stents:EPIC05-Sierra75 study显示文摘OBJECTIVES Elderly patients show a higher incidence of ischemic and bleeding events after percutaneous transluminal coron-ary intervention(PCI).We sought to investigate outcomes in elderly patients treated with antithrombotic strategy guided by bleeding and ischemic risks after revascularization with last generation everolimus-eluting stent(EES).METHODS Prospective multicenter registry including patients over 75 years revascularized with EES and antithrombotic ther-apy guided by clinical presentation,PCI complexity and PRECISE DAPT score.Co-primary safety endpoints were:(1)composite of cardiac death,myocardial infarction and stent thrombosis and;(2)bleeding(BARC 2-5).Primary efficacy endpoint was target lesion revascularization.A matched group of patients revascularized with current drug-eluting stents and no such tailored antith-rombotic therapy was used as control.RESULTS Finally,1064 patients were included in SIERRA-75 cohort,80.8±4.2 years,36.6%women,71%acute coronary syn-dromes(ACS)and 53.6%complex PCI.Co-primary safety endpoint of major adverse cardiovascular events was met in 6.2%,co-primary safety endpoint of bleeding in 7.8%and primary efficacy endpoint of TKLR in 1.5%.The multivariable adjusted model showed no significant association of the prescribed short/long dual antiplatelet therapy(DAPT)durations with any endpoint suggesting a well tailored therapy.No stent thrombosis reported in the subgroup with 1-3 months DAPT duration.As compared to control group,bleeding BARC 2-5 was significantly lower in SIERRA-75 group(7.4%vs.10.2%,P=0.04)as well as the net safety-efficacy endpoint(14.3%vs.18.5%,P=0.02).CONCLUSIONS In elderly population,the application of this risks-adjusted antithrombotic protocol after revascularization with last generation EES seems to be associated with an improved prognosis in terms of ischemic and bleeding outcomes. | Jose M de la Torre Hernandez Ramon Lopez Palop Jesus M Jimenez Mazuecos Pilar Carrillo Sáez Alejandro Gutierez-Barrios Eduardo Pinar Belen Cid Luis Fernandez Tamara Garcia Camarero Cristóbal Urbano-Carrillo Juan F Oteo Dominguez Victor A Jimenez Diaz Antonio EGomez Menchero Eladio Galindo Fernández Juan GCórdoba Soriano Raymundo Ocaranza Eduardo ArroyoÚcar Koldobika Garcia San Roman Silvio Leal Ginés Martínez Cáceres Jose A Linares Vicente Georgina Fuertes Ferre Xavier Carrillo Juan CRama Merchán Catia Costa Juan Sanchis Renato Fernandes Alberto Rodrigues Jose M Vegas Valle Hélder Pereira Armando Perez de Prado | 2022 | Journal of Geriatric Cardiology2022，19，5： | 0 |
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