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| 1 | Management of hepatocellular carcinoma with portal vein tumor thrombosis: Review and update at 2016显示文摘Portal vein tumor thrombosis(PVTT) is a common phenomenon in hepatocellular carcinoma(HCC). Compared to HCC without PVTT, HCC with PVTT is characterized by an aggressive disease course, worse hepatic function, a higher chance of complications related to portal hypertension and poorer tolerance to treatment. Conventionally, HCC with PVTT is grouped together with metastatic HCC during the planning of its management, and most patients are offered palliative treatment with sorafenib or other systemic agents. As a result, most data on the management of HCC with PVTT comes from subgroup analyses or retrospective series. In the past few years, there have been several updates on management of HCC with PVTT. First, it is evident that HCC with PVTT consists of heterogeneous subgroups with different prognoses. Different classifications have been proposed to stage the degree of portal vein invasion/thrombosis, suggesting that different treatment modalities may be individualized to patients with different risks. Second, more studies indicate that more aggressive treatment, including surgical resection or locoregional treatment, may benefit select HCC patients with PVTT. In this review, we aim to discussthe recent conceptual changes and summarize the data on the management of HCC with PVTT. | Stephen L Chan Charing CN Chong Anthony WH Chan Darren MC Poon Kenneth SH Chok | 2016 | World Journal of Gastroenterology2016，22，32： | 44 |
| 2 | Nonenzymatic antioxidant activity of four organ sulfur compounds derived from garlic显示文摘 | Yin MC Hwang SW Chan KC | 2002 | J Agric Food Chem2002，50，21： | 1 |
| 3 | Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression显示文摘 | Chan MC Hilyard AC Wu C | 2010 | EMBO J2010，29，： | 1 |
| 4 | Effects of TGF-13s on the growth, collagen synthesis and collagen lattice contrac- tion of human dental pulp fibroblasts in vitro显示文摘 | Chan CP Lan WH Chang MC | 2005 | Arch Oral Biol2005，50，5： | 1 |
| 5 | Chromosomal localization of the human NF-E2 family of bZIP transcription factors by fluorescence in situ hybridization显示文摘 | Chan JY Cheung MC Moi P | | 0，，03： | 1 |
| 6 | Adenosquamous/squamous cell carcinoma of the gallbladder 显示文摘 | Chan KM Yu MC Lee WC | 2007 | J Surg Oncol2007，95，2： | 1 |
| 7 | Etiology and cytokine expression in patients requiring mechanical ventilation due to severe community-acquired pneumonia 显示文摘 | Wu CL Chan MC Chang GC | 2006 | Formos Med Assoc2006，105，1： | 1 |
| 8 | Facial emotion processing in schizophremia:a meta-analysis of functional neuroimaging data显示文摘 | Li H Chan RC Mc Alonan GM | 2010 | Schizophr Bull2010，36，5： | 1 |
| 9 | Diabetes and thehyl Do- thalamo-pituitary-adrenal(HPA) axis 显示文摘 | Chan O Inouye K Riddeli MC | 2005 | Minerva Endocrinol2005，28，： | 1 |
| 10 | Epidemiologic risk profile of infection with different groups of human papillomaviruses 显示文摘 | Chan PK Ho WC Wong MC | 2009 | J Med Virol2009，81，9： | 1 |
| 11 | Timing for initia- tion of continuous renal replacement therapy in patients with septic shock and acute kidney injury显示文摘 | Shum HP Chan KC Kwan MC | 2013 | Ther Apher Dial2013，17，3： | 1 |
| 12 | Executive function deficits and neural discordance in children with autism spectrum disorders 显示文摘 | Chan AS Cheung MC Han YM | 2009 | Clin Neurophysiol2009，120，6： | 1 |
| 13 | Sapovirus detectionby quantitative real-time RT-PCR in clinical stool specimens显示文摘 | CHAN MC SUNG JJ LAM RK | 2006 | J Virol Methods2006，134，12： | 1 |
| 14 | DASI81, a sialidase fusion protein ,protects human airway epithelium against influenza virus infection : an in vitro pharmacodynamic analysis 显示文摘 | Triana - Baltzer GB Babizki M Chan MC | 2009 | J Antimicrob Che- mother2009，65，： | 1 |
| 15 | Benefits of a pediatric an-timicrobial stewardship program at a children′s hospital显示文摘 | Di Pentima MC Chan S Hossain J | 2011 | Pediatrics2011，128，6： | 1 |
| 16 | Angiopoietin -like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice显示文摘 | Xu A Lam MC Chan KW | 2005 | Proc Natl Acad Sci USA2005，102，17： | 1 |
| 17 | Effect of diallyl trisulfiderich garlic oil on blood coagulation and plasma activity of anticoagulation factors in rats显示文摘 | Chan KC Yin MC Chao WJ | 2007 | Food Chem Toxicol2007，45，3： | 1 |
| 18 | Comparison of Fcγ receptor expression on neutrophils with procalcitonin for the diagnosis of sepsis in critically illpatients显示文摘 | Hsu KH Chan MC Wang JM | 2011 | Respirology2011，16，1： | 1 |
| 19 | The superiority of hybrid-volumetric arc therapy(VMAT) technique over double arcs VMAT and 3D-conformal technique in the treatment of locally advanced non-small cell lung cancer-a planning study显示文摘 | Chan OS Lee MC Hung AW | 2011 | Radiother Oncol2011，101，2： | 1 |
| 20 | Evaluation of a new inflammatory molecule (triggering receptor expressed on myeloid cells-1) in the diagnosis of pleural effusion显示文摘 | Chan MC Chang KM Chao WC | 2007 | Respirology2007，12，3： | 1 |
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