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| 1 | Atrophic gastritis: Risk factor for esophageal squamous cell carcinoma in a Latin-American population显示文摘AIM: To study the association between atrophic gastritis (AG) and esophageal squamous cell carcinoma (ESCC) in a Latin-America population. METHODS: A case-control study was performed at two reference Brazilian hospitals including patients diagnosed with advanced ESCC and dyspeptic patients who had been subjected to upper gastrointestinal endoscopy, with biopsies of the gastric antrum and body.All cases with ESCC were reviewed by a single pathologist, who applied standard criteria for the diagnosis of mucosal atrophy, intestinal metaplasia, and dysplasia, all classified as AG. The data on the patients' age, sex, smoking status, and alcohol consumption were collected from clinical records, and any missing information was completed by telephone interview. The association between AG and ESCC was assessed by means of univariate and multiple conditional logistic regressions. RESULTS: Most patients were male, and the median age was 59 years (range: 37-79 years) in both the ESCC and control groups. Univariate analysis showed that an intake of ethanol greater than 32 g/d was an independent risk factor that increased the odds of ESCC 7.57 times (P = 0.014); upon multiple analysis, alcohol intake of ethanol greater than 32 g/d exhibited a risk of 4.54 (P = 0.081), as adjusted for AG and smoking. Smoking was shown to be an independent risk factor that increased the odds of ESCC 14.55 times (P = 0.011) for individuals who smoked 0 to 51 packs/year and 21.40 times (P = 0.006) for those who smoked more than 51 packs/year. Upon multiple analyses, those who smoked up to 51 packs/year exhibited a risk of 7.85 (P = 0.058), and those who smoked more than 51 packs/ year had a risk 11.57 times higher (P = 0.04), as adjusted for AG and alcohol consumption. AG proved to be a risk factor that increased the odds of ESCC 5.33 times (95%CI: 1.55-18.30, P = 0.008) according to the results of univariate conditional logistic regression. CONCLUSION: There was an association by univariate conditional logistic regression between AG and ECSS in this sample of Latin-American population. | Emiliano de Carvalho Almodova Walmar Kerche de Oliveira Lucas Faria Abraho Machado Juliana Rigotto Grejo Thiago Rabelo da Cunha Wagner Colaiacovo Erika Veruska Paiva Ortolan | 2013 | World Journal of Gastroenterology2013，19，13： | 5 |
| 2 | Potential role of Limosilactobacillus fermentum as a probiotic with anti-diabetic properties: A review显示文摘Oxidative stress,inflammation,and gut microbiota impairments have been implicated in the development and maintenance of diabetes mellitus.Strategies capable of recovering the community of commensal gut microbiota and controlling diabetes mellitus have increased in recent years.Some lactobacilli strains have an antioxidant and anti-inflammatory system capable of protecting against oxidative stress,inflammation,and diabetes mellitus.Experimental studies and some clinical trials have demonstrated that Limosilactobacillus fermentum strains can beneficially modulate the host antioxidant and anti-inflammatory system,resulting in the amelioration of glucose homeostasis in diabetic conditions.This review presents and discusses the currently available studies on the identification of Limosilactobacillus fermentum strains with anti-diabetic properties,their sources,range of dosage,and the intervention time in experiments with animals and clinical trials.This review strives to serve as a relevant and well-cataloged reference of Limosilactobacillus fermentum strains capable of inducing anti-diabetic effects and promoting health benefits. | Diego Cabral Lacerda Paulo César Trindade da Costa Paula Brielle Pontes Lucas Alves Carneiro dos Santos JoséPatrocínio Ribeiro Cruz Neto Cristiane Cosmo Silva Luis Vanessa Polyana de Sousa Brito JoséLuiz de Brito Alves | 2022 | World Journal of Diabetes2022，13，9： | 3 |
| 3 | Streptococcus agalactiae:Identification methods,antimicrobial susceptibility, and resistance genes in pregnant women显示文摘BACKGROUND Group B Streptococcus(GBS)is a normal component of the gastrointestinal and genital microbiota in humans and can lead to important infections in newborns.AIM To compare GBS isolation and identification methods as well as to assess the antibiotic susceptibility and to identify resistance genes in GBS strains from pregnant women attended in healthcare services from the city of Vitória da Conquista,in Bahia State,Brazil.METHODS From January 2017 to February 2018,vaginorectal swabs were obtained from 186 participants and the samples were seeded onto chromogenic agar for GBS before and after inoculation in selective broth.Confirmatory identification using 3 CAMP and latex tests was performed in samples with GBS-suggestive colonies.Then,disk diffusion antibiograms were performed in GBS-positive samples,and the detection of the resistance genes ermB,ermTR,mefA,and linB in the clindamycin and/or erythromycin-resistant samples was carried out.RESULTS Thirty-two samples(17.2%)were GBS-positive.The culture in chromogenic agar after sample incubation in selective broth was the most sensitive method(96.9%)for GBS detection.All isolates were susceptible to penicillin,ampicillin,cefotaxime,and vancomycin.Clindamycin resistance was observed in 6 samples(18.8%),while 8 samples(25%)were erythromycin-resistant.All erythromycin and/or clindamycin-resistant GBS strains had negative D-tests.Two strains(25%)presented an M phenotype and 6 isolates(75%)presented a cMLSB phenotype.The ermB gene was identified in 4 samples(44.4%),the mefA gene was also found in 4 samples(44.4%),the ermTR gene was identified in 1 isolate(11.1%),and the linB gene was not found in any isolate.CONCLUSION This study evidenced that the screening for SGB can be performed by means of various methods,including chromogenic media,and that the chemoprophylaxis for pregnant women who cannot use penicillin must be susceptibility-guided. | Fabrícia Almeida Fernandes Santana Tais Viana Ledo de Oliveira Marcelo Barreto de Souza Filho Lucas Santana Coelho da Silva Breno Bittencourt de Brito Fabrício Freire de Melo Cláudio Lima Souza Lucas Miranda Marques Márcio Vasconcelos Oliveira | 2020 | World Journal of Clinical Cases2020，8，18： | 2 |
| 4 | Contruct stiffness of different fixation methods for supracondylar femoral fractures above knee prostheses显示文摘 | Gusick RP Lucas GL Mcqueen DA | 2000 | Am J orthop2000，29，9： | 1 |
| 5 | Unplanned extubation in pediat-ric critically ill patients : a systematic review and best practive recom-medations 显示文摘 | Lucas da Silva PS de Carvalho WB | 2010 | Pediatric Critical Care Med2010，11，2： | 1 |
| 6 | Identification of the SELDI protein chip human serum retentate by microcapillary liquid chromatography-tandem mass spectrometry显示文摘 | Zhou M Prieto DA Lucas DA | 2006 | J Proteome Res2006，5，9： | 1 |
| 7 | Adhesive joints at high and low temperatures using similar and dissimilar adherends and dual adhesives 显示文摘 | Lucas F M da Silva Adams R D | 2007 | International Journal of Adhesion & Adhesives2007，27，： | 1 |
| 8 | Electrocardiographic criteria for vagotonia—validation with pharmacological parasympathetic blockade in healthy subjects显示文摘 | José Kawazoe Lazzoli Pedro Paulo da Silva Soares Antonio Claudio Lucas da Nóbrega Claudio Gil Soares de Araújo | 2002 | International Journal of Cardiology2002，，2： | 1 |
| 9 | Preoperative rectal tumor embolization as an adjunctive tool for bloodless abdominoperineal excision:A case report显示文摘BACKGROUND Abdominoperineal excision(APE)-related hemorrhage can be challenging due to difficult access to pelvic organs and the risk of massive blood loss.The objective of the present study was to demonstrate the use of preoperative embolization(PE)as a strategy for blood preservation in a patient with a large low rectal tumor with a high risk of bleeding,scheduled for APE.CASE SUMMARY A 56-year-old man presented to our institution with a one-year history of anal bleeding and rectal tenesmus.The patient was diagnosed with bulky adenocarcinoma limited to the rectum.As the patient refused any clinical treatment,surgery without previous neoadjuvant chemoradiation was indicated.The patient underwent a tumor embolization procedure,two days before surgery performed via the right common femoral artery.The tumor was successfully devascularized and no major bleeding was noted during APE.Postoperative recovery was uneventful and a one-year follow-up showed no signs of recurrence.CONCLUSION Therapeutic tumor embolization may play a role in bloodless surgeries and increase surgical and oncologic prognoses.We describe a patient with a bulky low rectal tumor who successfully underwent preoperative embolization and bloodless abdominoperineal resection. | Marley Ribeiro Feitosa Lucas Fernandes de Freitas Antonio Balestrim Filho Guilherme Seizem Nakiri Daniel Giansante Abud Ligia Magnani Landell Mariângela Ottoboni Brunaldi Jose Joaquim Ribeiro da Rocha Omar Feres Rogério Serafim Parra | 2020 | World Journal of Clinical Oncology2020，11，12： | 1 |
| 10 | Repair of articular cartil age defects using mesenchymal stem cells显示文摘 | Lucas PA Manji R | 1995 | Tissue Eng1995，4，： | 1 |
| 11 | Orthopedic injuryies from the Andover,Kansas tornado显示文摘 | Rosenfield LA McQueen DA Lucas GL | | 0，，： | 1 |
| 12 | Manufacture of Adhesive Joints and Bulk Specimens with High-temperature Adhesives显示文摘 | Lucas F M Da Silva R D Adams | 2004 | International Journal of Adhesion and Adhesives2004，24，1： | 1 |
| 13 | One year soy protein supple- mentation has positive effects on bone formation markers but not bone density in postmenopausal women 显示文摘 | Arjmandi BH Lucas EA Khalil DA | 2005 | Nutr J2005，23，4： | 1 |
| 14 | Revisited anatomy of lhe recurrent laryngeal nerves 显示文摘 | Guglielmo A Luca R Lucia DA | 2004 | Am J Surg2004，187，2： | 1 |
| 15 | The use of urine proteomic and metabonomic patterns for the diagnosis of interstitial cystitis and bacterial cystitis显示文摘 | Van QN Klose JR Lucas DA | 2004 | Dis Markers2004，19，45： | 1 |
| 16 | Ethanol-extracted soy protein isolate does not modulate serum cholesterol in golden Syrian hamsters: a model of postmenopausal hypercholesterolemia显示文摘 | Lucas EA Khalil DA Daggy BP | 2001 | J Nutr2001，131，2： | 1 |
| 17 | Revisited anatomy of the recurrent laryngeal nerves显示文摘 | Guglielmo A Luca R Lucia DA | 2004 | Am J Surg2004，187，2： | 1 |
| 18 | Bidens pilosa L. Exhibits High Sensitivity to Coumarin in Comparison with Three Other Weed Species显示文摘 | érica Marusa Pergo Denise Abrahim Patrícia Cristina Soares da Silva Kátia Aparecida Kern Lucas Jonatas Silva Elemar Voll Emy Luiza Ishii-Iwamoto | 2008 | Journal of Chemical Ecology2008，，4： | 1 |
| 19 | Direct ampholyte-free liquidphase isoelectrie peptide focusing: application to the human serum proteome 显示文摘 | Xiao Z Conrads TP Lucas DA | 2004 | Electrophoresis2004，25，1： | 1 |
| 20 | An experimental comparison of a graphite electrode and a gas diffusion electrode for the cathodic production of hydrogen peroxide显示文摘 | Anna Da Pozzo Luca Di Palma Carlo Merli Elisabetta Petrucci | 2005 | Journal of Applied Electrochemistry2005，，4： | 1 |
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