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    题名 作者 年代 出处 被引量
1Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment显示文摘Pu Li Jing-Xuan Shan Xue-Hua Chen Di Zhang Li-Ping Su Xiu-Ying Huang Bei-Qin Yu Qiao-Ming Zhi Cheng-Long Li Ya-Qing Wang Sara Tomei Qu Cai Jun Ji Jian-Fang Li Lotfi Chouchane Ying-Yan Yu Fang-Zhen Sun Zhi-Heng Xu Bing-Ya Liu Zheng-Gang Zhu 2015Cell Research2015,25,5:24
2Physiological responses of Brassica napus to fulvic acid under water stress: Chlorophyll a fluorescence and antioxidant enzyme activity显示文摘The ameliorative effect of fulvic acid(0, 300, and 600 mg L-1) on photosystem II and antioxidant enzyme activity of the rapeseed(Brassica napus L.) plant under water stress(60, 100, and 140 mm evaporation from class A pan) was studied using split plots in a randomized complete block design with three replications. Results indicated that application of fulvic acid(FA) improved the maximum quantum efficiency of PSII(Fv/Fm)and performance index(PI) of plants under both well-watered and limited-water conditions. The time span from Foto Fmand the energy necessary for the closure of all reaction centers was significantly increased, but the size of the plastoquinone pool was reduced with increasing water stress levels. Plants treated with FA had higher peroxidase and catalase activities under all irrigation conditions. Activities of ascorbate peroxidase and superoxide dismutase in plants increased with increasing water stress. Malondialdehyde increased under severe water stress, but application of FA significantly decreased lipid peroxidation. Production of reactive oxygen species(ROS) is a common phenomenon in plants under stress. Under this condition, the balance between the production of ROS and the quenching activity of antioxidants is upset, often resulting in oxidative damage. In this study, application of FA significantly increased fluorescence of chlorophyll a, inhibiting ROS production and enhancing antioxidant enzymes activity that destroyed ROS. Thus, ROS in plant cells was reduced under water stress by application of FA and consequently lipid peroxidation was reduced.Ramin Lotfi Mohammad Pessarakli Puriya Gharavi-Kouchebagh Hossein Khoshvaghti 2015The Crop Journal2015,3,5:16
3基于分裂基-2/(2a)FFT算法的卷积神经网络加速性能的研究显示文摘卷积神经网络在语音识别和图像识别等众多领域取得了突破性进展,限制其大规模应用的很重要的一个因素就是其计算复杂度,尤其是其中空域线性卷积的计算。利用卷积定理在频域中实现空域线性卷积被认为是一种非常有效的实现方式,该文首先提出一种统一的基于时域抽取方法的分裂基-2/(2a)1维FFT快速算法,其中a为任意自然数,然后在CPU环境下对提出的FFT算法在一类卷积神经网络中的加速性能进行了比较研究。在MNIST手写数字数据库以及Cifar-10对象识别数据集上的实验表明:利用分裂基-2/4 FFT算法和基-2 FFT算法实现的卷积神经网络相比于空域直接实现的卷积神经网络,精度并不会有损失,并且分裂基-2/4能取得最好的提速效果,在以上两个数据集上分别提速38.56%和72.01%。因此,在频域中实现卷积神经网络的线性卷积操作是一种十分有效的实现方式。伍家松 达臻 魏黎明 SENHADJI Lotfi 舒华忠 2017电子与信息学报2017,39,2:8
4Elevated temperature oxidation behavior of HVOF sprayed TiB_2 cermet coating显示文摘Oxidation behaviors of Ni(Cr)-TiB2 coating deposited by HVOF technique were studied at 800,900 and 1 000℃in air. The microstructures of as-sprayed and oxidized coatings were characterized by X-ray diffractometry(XRD)and scanning electron microscopy(SEM).After oxidation at 800℃,a thin and adherent oxide layer was formed on the surface of the coating.With increasing exposure temperature,the thickness of the oxide layer increased;and at 1 000℃the oxide layer separated from the coating.Investigation of the kinetics of oxidation by using the thermogravimetric analysis(TGA)technique shows a parabolic oxidation rate.Behnam LOTFI 2010Transactions of Nonferrous Metals Society of China2010,20,2:7
5方波伏安法测定新型修饰多壁碳纳米管糊电极对肼的电催化氧化(英文)显示文摘The application of p-aminophenol as a suitable mediator, as a sensitive and selective voltammetric sensor for the determination of hydrazine using square wave voltammetric method were described. The modified multiwall carbon nanotubes paste electrode exhibited a good electrocatalytic activity for the oxidation of hydrazine at pH = 7.0. The catalytic oxidation peak currents showed a linear dependence of the peaks current to the hydrazine concentrations in the range of 0.5–175 μmol/L with a correlation coefficient of 0.9975. The detection limit (S/N = 3) was estimated to be 0.3 μmol/L of hydrazine. The relative standard deviations for 0.7 and 5.0 μmol/L hydrazine were 1.7 and 1.1%, respectively. The modified electrode showed good sensitivity and selectivity. The diffusion coefficient (D = 9.5 × 10–4 cm2/s) and the kinetic parameters such as the electron transfer coefficient (α = 0.7) of hydrazine at the surface of the modified electrode were determined using electrochemical approaches. The electrode was successfully applied for the determination of hydrazine in real samples with satisfactory results.Ali A. ENSAFI Mahsa LOTFI Hassan KARIMI-MALEH 2012催化学报2012,33,3:6
6面向图像分类的核主成分分析网络(英文)显示文摘为了能够用线性分类器对非线性特征进行分类,同时提高图像的分类正确率,提出了一种核主成分分析网络(KPCANet).首先通过核主成分分析算法将数据映射到高维空间中,使得数据线性可分,然后建立一个2层的KPCANet,提取出图像的主特征,最后将图像的主特征输入线性分类器中进行分类.实验结果表明,KPCANet对于人脸识别、物体识别以及手写数字识别效果良好,其分类效果优于现存的主成分分析网络(PCANet).同时,KPCANet的成分提取效果不受光照条件变化的影响,且对于遮挡以及微小的形变提取效果稳定.吴丹 伍家松 曾瑞 姜龙玉 Lotfi Senhadji 舒华忠 2015Journal of Southeast University(English Edition)2015,31,4:5
7Influence of Sludge Incineration Ash on Ryegrass Growth and Soil Phosphorus Status显示文摘Phosphorus(P) is a limited resource that could be depleted. Consequently, recycling the P contained in sewage sludge, including sewage sludge incineration ash(SIA), from wastewater treatment plants is a possibility to be explored. A greenhouse experiment using annual ryegrass(Lolium multiflorum L.) was performed with an experimental design of three completely randomized blocks of two soils and 29 treatments: one control without P and two levels of 9 and 26 kg total P ha^(-1) from 14 different sources: twelve SIAs(not contaminated by trace metals) from the US and Canada, one commercial synthetic fertilizer(triple superphosphate(TSP)), and one commercial rock phosphate(RP). Higher ryegrass biomass levels were achieved at the higher fertilization rate(26 kg total P ha^(-1))and when using the SIAs with the highest P solubility percentage(PSP)(≥ 54% of total P). The biomass increases following SIA application were as high as 29% and 59% more than the control for the sandy loam and clayey soil, respectively, but 40% less than in TSP for both soils. A similar behavior was observed for P uptake, with a maximum increase of 26% for the clayey soil, and 165% for the sandy loam soil. The ryegrass biomass and P uptake increases due to SIA application were larger than those due to RP application in the clayey soil, but similar to those in the sandy loam soil. The SIAs with a PSP of ≥ 54% significantly increased soil available P stocks and saturation. According to our findings, we conclude that the SIAs from municipal and agrifood industries have a potential for P agricultural recycling, but their efficiencies vary.Claude-Alla JOSEPH Lotfi KHIARI Jacques GALLICHAND Marc HBERT Ned BEECHER 2019Pedosphere2019,29,1:4
8Design issues for human-machine platform interface in cable-based parallel manipulators for physiotherapy applications显示文摘We outline problems and potential solutions for feasible human-machine interfaces using cable-based parallel manipulators for physiotherapy applications.From an engineering perspective,we discuss the design constraints related to acceptance by patients and physiotherapist users.To date,most designs have focused on mobile platforms that are designed to be operated as an end-effector connected to human limbs for direct patient interaction.Some specific examples are illustrated from the authors' experience with prototypes available at Laboratory of Robotics and Mechatronics (LARM),Italy.Marco CECCARELLI Lotfi ROMDHANE 2010Journal of Zhejiang University-Science A(Applied Physics & Engineering)2010,11,4:4
9Design Study of a Cable-based Gait Training Machine显示文摘这份报纸处理基于量的步法分析训练机器的步法的一条设计途径。建议训练机器由一台身体重量支持设备和一个电缆线驱动的平行机器人组成。这份报纸集中于电缆线驱动的机器人,它通过放在病人腿上的 orthosis 控制更低的手足的姿势。电报机器人通过 orthosis 的运动复制一个正常步法运动。一个运动俘获系统被用来执行正常步法的定量分析,它将被用作输入到电缆线机器人的反的动态模型。借助于一个优化算法,最佳的设计参数,在电报最小化紧张,是坚定的。二限制被考虑,即,在电报的非否定的紧张一直,并且免费 cable/end-effector 碰撞。一旦最佳的答案被计算,力量分析被执行以便缩放机器人致动器。建议途径能容易为电报机器人的一种类似的类型的设计学习被扩大。Houssein Lamine Med Amine Laribi Sami Bennour Lotfi Romdhane Said Zeghloul 2017Journal of Bionic Engineering2017,14,2:4
10Hydrogen Detection With FBG Sensor Technology for Disaster Prevention显示文摘Said SAAD Lotfi HASSINE 2013Photonic Sensors2013,3,3:4
11Characterization of two rat models of cystic fibrosis—KO and F508del CFTR—Generated by Crispr-Cas9显示文摘Background: Genetically engineered animals are essential for gaining a proper understanding of the disease mechanisms of cystic fibrosis(CF). The rat is a relevant laboratory model for CF because of its zootechnical capacity, size, and airway characteristics, including the presence of submucosal glands.Methods: We describe the generation of a CF rat model(F508 del) homozygous for the p.Phe508 del mutation in the transmembrane conductance regulator(Cftr) gene. This model was compared to new Cftr-/-rats(CFTR KO). Target organs in CF were examined by histological staining of tissue sections and tooth enamel was quantified by micro-computed tomography. The activity of CFTR was evaluated by nasal potential difference(NPD) and short-circuit current measurements. The effect of VX-809 and VX-770 was analyzed on nasal epithelial primary cell cultures from F508 del rats.Results: Both newborn F508 del and Knock out(KO) animals developed intestinal obstruction that could be partly compensated by special diet combined with an osmotic laxative. The two rat models exhibited CF phenotypic anomalies such as vas deferens agenesis and tooth enamel defects. Histology of the intestine, pancreas, liver, and lungs was normal. Absence of CFTR function in KO rats was confirmed ex vivo by short-circuit current measurements on colon mucosae and in vivo by NPD, whereas residual CFTR activity was observed in F508 del rats. Exposure of F508 del CFTR nasal primary cultures to a combination of VX-809 and VX-770 improved CFTR-mediated Cl-transport.Conclusions: The F508 del rats reproduce the phenotypes observed in CFTR KO animals and represent a novel resource to advance the development of CF therapeutics.Elise Dreano Marc Bacchetta Juliette Simonin Louise Galmiche Claire Usal Lotfi Slimani Jérémy Sadoine Laurent Tesson Ignacio Anegon Jean-Paul Concordet Aurélie Hatton Lucile Vignaud Danielle Tondelier Isabelle Sermet-Gaudelus Marc Chanson Charles-Henry Cottart 2019Animal Models and Experimental Medicine2019,2,4:3
12Caries-related factors and bacterial composition of supragingival plaques in caries free and caries active Algerian adults显示文摘Objective: To compare oral hygiene practices, education and social background, food intake and oral malodor of Algerian adults suffering from dental caries with normal controls, and to determine and compare the bacterial composition of the supragingival plaques from the above-mentioned groups.Methods: Participants completed a questionnaire and were clinically examined for dental caries using decayed, missing and filled teeth index according to the criteria laid down by the World Health Organization. Supragingival plaque samples were collected from 50 caries-free adults(CF) and 50 caries-active adults(CA). Standard procedures of culture and identification of aerobic and anaerobic bacteria were used. Data were analyzed using Chi-square test.Results: A total of 117 bacterial strains were isolated from supragingival plaques in CF group subjects, 76(64.96%) of them belonged to 9 aerobic genera, and 41(35.04%) to 9anaerobic genera(P < 0.05). While in the second group, 199 strains were isolated, 119(59.80%) of the strains belonged to 10 aerobic genera and 80(40.20%) to 10 anaerobic bacteria(P < 0.05). Streptococcus mutans, Enterococcus faecium, Aerococcus viridans,Actinomyces meyeri, Lactobacillus acidophilus and Eubacterium limosum showed a significantly higher prevalence in the CA group(P < 0.05). The findings revealed that CA group had a high sugar intake(80%). A significantly higher frequency of tooth brushing(P < 0.000) and a significantly less self-reported oral malodor(P < 0.000) and tooth pain(P < 0.000) were found in CF group, while there was no association of socioeconomic levels and intake of meal snacks with dental caries.Conclusions: This study confirms the association of some aciduric bacteria with caries formation, and a direct association of sugar intake and cultural level with dental caries.Furthermore, oral hygiene practices minimize the prevalence of tooth decay.Amina Hoceini Nihel Klouche Khelil Ilhem Ben-Yelles Amine Mesli Sara Ziouani Lotfi Ghellai Nadia Aissaoui Fatima Nas Mounia Arab 2016Asian Pacific Journal of Tropical Biomedicine2016,6,8:3
13Production of single-walled carbon nanotubes from methane over Co-Mo/MgO nanocatalyst:A comparative study of fixed and fluidized bed reactors显示文摘In this study,the performances of fixed and fluidized bed reactors in the production of single-walled carbon nanotubes(SWNTs)have been investigated.In both reactors,single-walled carbon nanotubes were grown by catalytic chemical vapor decomposition(CCVD)of methane over Co-Mo/MgO nanocatalyst under two different operating conditions.The synthesized samples were characterized by TEM,TGA and Raman spectroscopy.It is found that the performance of a fluidized bed in the synthesis of carbon nanotubes is much better than that of a fixed bed.The quality of carbon nanotubes obtained from the fluidized bed was significantly higher than that from the fixed bed and the former one with the ID/IG ratio of 0.11 while the latter one with the ID/IG ratio of 0.71.Also,the yield of SWNTs in the fluidized bed was 92 wt%,while it was 78 wt%in the fixed bed.These advantages of fluidized bed reactors for the synthesis of carbon nanotubes can be attributed to more available space for the growth of carbon nanotubes and more uniform temperature and concentration profiles.Alimorad Rashidi Roghayeh Lotfi Ehsaneh Fakhrmosavi Masoud Zare 2011Journal of Natural Gas Chemistry2011,20,4:3
14Evaluation of the Effects of Cypermethrin on Female Reproductive Function by Using Rabbit Model and of the Protective Role of Chinese Propolis显示文摘对 cypermethrin 毒性的中国 propolis 的预防效果被执行卵巢和子宫组织病理学说,以及由描绘卵巢的功能,胚胎,和崽评估。Cypermethrin 在卵巢和子宫导致了 atypia,并且减少排卵地点和胚胎的数字。导致 Cypermethrin 的氧化应力在怀孕期间,减少后代的生产率以及数字和重量并且在后代增加了词法畸形性的发生。到对待 cypermethrin 的动物的 propolis 的管理减轻了导致 cypermethrin 的繁殖毒性。AE Khatab NM Hashem LM El-Kodary FM Lotfy GA Hassan 2016Biomedical and Environmental Sciences2016,29,10:3
15Microstructure and Sliding Wear Behaviour of Ni(Cr)-TiB_2 Coatings Deposited by HVOF Spraying of SHS Powders显示文摘This work reports research concerning the microstructure and sliding wear behaviour of cermet coatings deposited by high velocity oxy-fuel (HVOF) spraying. Two cermets were prepared with the following target compositions namely, Ni (Cr)-65 wt.% TiB2 and Ni (Cr)-40 wt.% TiB2. Coating microstructures were investigated by scanning electron microscopy (SEM) and X-ray diffraction (XRD), whilst microhardness and sliding wear tests were performed on the coatings to evaluate their performance. The HVOF sprayed deposits had layered, splat-like morphologies typical of thermally sprayed cermets. Coatings consisted primarily of TiB2 particles in a nickel-based binder phase. Other minor peaks in the XRD patterns belong to TiB, Ni2B, NiTiO3 and Ti2Oj. The coatings exhibit an amorphous halo in the diffraction pattern between 2 values of 40° and 50°. Sliding wear behaviour was examined using a conventional ball-on-disc apparatus. A sintered ceramic ball (A12O3) was employed as the counterface. The Ni (Cr)-65 wt.% TiB2 coating had a lower wear rate than Ni (Cr)-40 wt.% TiB2 coating. This may be related to the larger sizes of borides. Wear scar morphologies, on both coatings were examined by using SEM and EDAX detecting in order to establish the wear mechanism. Wear is proposed to proceed by subsurface cracking in these coatings.Behnam Lotfi Zohreh Sadeghian 2004材料热处理学报2004,25,05B:3
16Efficacy and safety of botulinum toxin in treatment of anismus: A systematic review显示文摘AIM: To evaluate the efficacy and safety of botulinum toxin type A(BTX-A) in the management of patients with anismus. METHODS: An organized search of published literature was conducted using electronic databases including: Pub Med/MEDLINE, and Cochrane Central Register of Control ed Trials, also an internet-based search using 'Google Scholar' service was conducted. Both comparative and observational studies were included. We excluded irrelevant articles, editorials, case reports, reviews, and meta-analyses. The studies that followed the patients less than 6 mo were excluded. Variables collected were demographic data of the patients, technique of BTX-A injection and number of sessions, short-term and longterm clinical improvement, post-injection changes in electromyography(EMG), defecography, manometry, and balloon expulsion test, and complications recorded after BTX-A injection.RESULTS: Seven studies comprising 189 patients were included in the review. The median age of the patients was 41.2 years and female-to-male ratio was 1.3:1. The median dose of BTX-A injected per procedure was 100 IU(range, 20-100 IU). Lateral injection was done in five trails and combined lateral and posterior injections in two trials. Three studies used endorectal ultrasonographyguided technique, one study used EMG-guided technique,whereas the remaining three studies used manual palpation with the index finger. The median percentage of patients who reported initial improvement of symptoms was 77.4%(range 37.5%-86.7%), this percentage declined to a median of 46%(range 25%-100%) at 4 mo after injection of BTX-A. Rates of improvement evaluated by balloon expulsion test, EMG, and defecography ranged between(37.5%-80%),(54%-86.7%), and(25%-86.6%), respectively. Fourteen(7.4%) patients developed complications after injection of BTX-A. Complication rates across the studies ranged from 0% to 22.6%. CONCLUSION: Initial satisfactory improvement of symptoms after BTX-A injection remarkably deteriorated after 3 mo of the procedure. However, repeated injection may provide better sustained results with no additional morbidities. Further analysis of more patients is necessary to conclude the safety of BTX-A for the treatment of anismus.Sameh Hany Emile Hossam Ayman Elfeki Hosam Ghazy Elbanna Mohamed Youssef Waleed Thabet Tito M Abd El-Hamed Basem Said Ahmed Lotfy 2016World Journal of Gastrointestinal Pharmacology and Therapeutics2016,7,3:3
17Effects of rhubarb(Rheum ribes L.)syrup on dysenteric diarrhea in children:a randomized,double-blind,placebo-controlled trial显示文摘BACKGROUND:Rheum ribes L.is a plant native to China,Iran,Turkey,India,and a few other countries.Antidiarrheal activity is considered to be one of its important properties according to various systems of traditional medicine.An increasing rate of bacterial resistance to antibiotics has led to treatment failure in some cases of shigellosis in children,and underlines a need for safe,efficient and valid options.OBJECTIVE:The purpose of this study is to evaluate the efficacy of R.ribes syrup as a complementary medicine for treatment of shigellosis in children.DESIGN,SETTING,PARTICIPANTS AND INTERVENTIONS:This randomized,doubleblind,placebocontrolled trial started with a group of 150 children aged between 12–72 months with suspected Shigella dysentery.R.ribes syrup or placebo syrup was administered to the intervention and control groups,respectively for 5 days.In addition,the standard antibiotic treatment(ceftriaxone for the first 3 days and cefixime syrup for 2 further days)was administered to both groups.MAIN OUTCOME MEASURES:Body temperature,abdominal pain,need for antipyretics,defecation frequency,stool volume and consistency and microscopic stool examination were recorded as outcome measures.Any observed adverse effects were also recorded.RESULTS:Mean duration of fever and diarrhea in the R.ribes group was significantly lower than that in the placebo group(P=0.016 and 0.001,respectively).In addition,patients in the R.ribes group showed shorter duration of need for antipyretics and shorter duration of abdominal pain(P=0.012 and 0.001,respectively).However,there were no significant differences between the two groups regarding the microscopic stool analyses.Furthermore,no adverse effect was reported.CONCLUSION:R.ribes syrup can be recommended as a complementary treatment for children with Shigella dysentery.Ali Khiveh Mohammad Hashem Hashempur Mehrdad Shakiba Mohammad Hassan Lotfi Afsaneh Shakeri Seid Kazem Kazemeini Zohre Mousavi Marzie Jabbari Mohammad Kamalinejad Majid Emtiazy 2017Journal of Integrative Medicine2017,15,5:3
18Anti-inflammatory and analgesic activities with gastroprotective effect of semi-purified fractions and isolation of pure compounds from Mediterranean gorgonian Eunicella singularis显示文摘Objective: To explore anti-inflammatory activities of organic extract and its semi-purified fractions(ethanol, acetone, methanol/dichloromethane) from the Mediterranean gorgonian Eunicella singularis. Methods: The anti-inflammatory and analgesic activities were evaluated, using the carrageenan-induced rat paw edema model and the acetic acid writhing test in mice. The gastroprotective activity was determined using HCl/Et OH induced gastric ulcers in rats. The purification and structure elucidation of compound(s) from the more effective fraction were determined by chromatographic and spectroscopic methods and in comparison with data reported in the literature. Results: The fraction F-Et OH showed an important antiinflammatory activity associated with significant analgesic and gastroprotective properties. The purification and structure elucidation of compound(s) from this fraction lead to the identification of one diterpenoid and four sterols. Conclusions: These results suggested that components from the active fraction can be used to treat various anti-inflammatory diseases.Monia Deghrigue Carmen Festa Lotfi Ghribi Maria Valeria D’Auria Simona De Marino Hichem Ben Jannet Abderrahman Bouraoui 2015Asian Pacific Journal of Tropical Medicine2015,8,8:2
19Removal of chromium(VI) from aqueous solution by activated carbons: Kinetic and equilibrium studies显示文摘Lotfi Khezami Richard Capart 2005Journal of Hazardous Materials2005,,1:2
20Hydrogen FBG Sensor Using Pd/Ag Film With Application in Propulsion System Fuel Tank Model of Aerospace Vehicle显示文摘高效率氢纤维布拉格栅栏(FBG ) 传感器被介绍。敏感电影是钯银(Pd-Ag ) 的一个新联盟。另外,钛(Ti ) 层被用作粘合剂层。介绍传感器显示出超过 60 pm/1% H 的决定 < 潜水艇 class= “ a-plus-plus ” > 2 , 和 4 s5 s 的一快反应时间在 0.1% H 被保证 < 潜水艇 class= “ a-plus-plus ” > 2 4% H < 潜水艇 class= “ a-plus-plus ” > 2 范围。而且,传感器的生活时间被调查。获得的结果证明传感器有一提高的生活时间。而且,传感器在太空车辆的推进系统燃料坦克模型被使用。获得的结果显示它由于氢漏是对灾难太空的一个预防系统。Said SAAD Lotfi HASSINE Vassim ELFAHEM 2014Photonic Sensors2014,4,3:2
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