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| 1 | IVF或ICSI周期卵巢过度刺激获取大量卵子并不会导致妊娠率降低显示文摘Objective: To investigate the possible negative effects of a strong ovarian response on oocyte quality.Design: Retrospective study.Setting: Tertiary academic center.Patient(s): A total of 1, 894 women (IVF, n = 1, 544; ICSI, n = 350) who underwent their first ovarian stimulation cycle during the period 1995- 2002.Intervention(s): Standardized controlled ovarian stimulation with urinary FSH or recombinant FSH after pituitary down- regulation, followed by IVF/intracytoplasmic sperm injection (ICSI) and ET.Main Outcome Measure(s): Fertilization rate, fraction of high- quality embryos, and implantation rate.Result(s): Using multivariate logistic regression, we analyzed the effect, expressed as an odds ratio (OR), of the number of oocytes obtained (i.e., ovarian response) on the outcome measures.No effect of the response on the ongoing implantation rate or fraction of high- quality embryos was observed.Both in IVF (OR = 0.81, 95% confidence interval [CI] 0.75- 0.87) and in ICSI (OR = 0.88, 95% CI 0.76- 1.00), a negative effect of increasing ovarian response was seen on the fertilization rate per oocyte obtained.However, no negative effect was observed on the fertilization rate per oocyte injected in ICSI (OR = 1.00, 95% CI 0.87- 1.14).The fraction of immature oocytes rises from 3.9% , in women with ≤ 3 oocytes, to 26% in women with > 20 oocytes.Conclusion(s): Oocytes from high responders contain a greater fraction of immature oocytes, but pregnancy outcome is not impaired. | Kok J.D. Looman C.W.N. Weima S.M. Te Velde E.R. 朱亮 | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，2，9： | 5 |
| 2 | 拔罐疗法对马匹背部肌肉机械痛阈的影响显示文摘目的:为了观察拔罐前后马匹背部肌肉机械痛阈的变化,为患背部疼痛马匹提供新的治疗思路。方法:将16匹正常成年马(3岁及以上)随机等分成试验组与对照组。对试验组马匹背部两侧的固定点位(n=8)进行拔罐疗法,对照组不做处理。试验前及试验后第2天使用测痛仪分别测量所有试验对象背部两侧固定点位(n=10)的机械痛阈,记录并分析数据。结果:试验组所有测量点位测量值在试验前后差异极显著(P<0.01),对照组差异不显著(P>0.05);试验前,试验组和对照组左右两侧测量值对比均差异极显著(P<0.01),试验后,试验组两侧测量值差异不显著(P>0.05),而对照组仍差异极显著(P<0.01)。结论:拔罐疗法可以显著提高马匹背部肌肉的机械痛阈,可以用于治疗马匹背部疼痛或背部敏感。 | 韦飞 Grigorios Maleas joop Loomans Marc Koene | 2018 | 中兽医医药杂志2018，37，6： | 2 |
| 3 | A high number of oocytes obtained after ovarian hyperstimulation for in vitro fertilization or intracytoplasmic sperm injection is not associated with decreased pregnancy outcome显示文摘 | Kok JD Looman CWN Weima SM | 2006 | Fertil Steril2006，85，4： | 1 |
| 4 | Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa显示文摘 | Marieke J van der Werf Sake J de Vlas Simon Brooker Caspar W.N Looman Nico J.D Nagelkerke J.Dik F Habbema Dirk Engels | 2003 | Acta Tropica2003，，2： | 1 |
| 5 | Predictors and a remedy for noncompliance with amblyopia thera- py in children measured with the occlusion dose moni- tor显示文摘 | Loudon S E Fronius M Looman C W | 2006 | Invest Ophthalmol Vis Sci2006，47，： | 1 |
| 6 | Outdoor air temperature and mortality in the Netherlands:a time-series analysis显示文摘 | Looman CW Mackenbach J | 1993 | Am J Epidemiol1993，137，： | 1 |
| 7 | Towards a Strategy for Airflow Simulation in Building Design Center fi~r Building & Systems TNO - TU/e 显示文摘 | Djunaedy E Hensen J L M & Loomans M G L C | 2002 | Technische Universiteit Eind- hoven2002，，： | 1 |
| 8 | External coupling between CFD and energy simulation: implementation and validation 显示文摘 | DJUNAEDY E HENSEN J LOOMANS M | 2005 | ASHRAE Transactions2005，，： | 1 |
| 9 | Burden of illness of diabetic macular edema:literature review显示文摘 | Chen E Looman M Laouri M | 2010 | Curr Med Res Opin2010，26，： | 1 |
| 10 | Gastric MALT lymphoma: Epidemiology and high adenocarcinoma risk in a nation-wide study显示文摘 | L.G. Capelle A.C. de Vries C.W.N. Looman M.K. Casparie H. Boot G.A. Meijer E.J. Kuipers | 2008 | European Journal of Cancer2008，，16： | 1 |
| 11 | Gastric :ancer risk in patients with premalignant gastric lesions: a lationwide cohort study in the Netherlands 显示文摘 | Je Vries AC van Grieken NC Looman CW | 2008 | }astroenterology2008，134，4： | 1 |
| 12 | Endothelial progenitor cell dysfunction:a novel concept in the pathogenesis of vascular complications of type 1 diabetes显示文摘 | Loomans CJ de Koning EJ Staal FJ | 2004 | Diabetes2004，53，1： | 1 |
| 13 | Impact of repeated antral follicle counts on the prediction of poor ovarian response in women undergoing in vitro fertilization显示文摘 | Bancsi L F Broekmans F J Looman C W | 2004 | Fertil Steril2004，81，1： | 1 |
| 14 | Neomin as an immunogen for the development of a generic ELISA detecting gentamicin, kanamycin, and neomycin in milk显示文摘 | LOOMANS E E Van WILTENBURG 3 KOETS M | 2003 | Journal of agricultural and food chemistry2003，51，3： | 1 |
| 15 | Outdoor air temperature and mortality in the Netherlands: a time-series analysis显示文摘 | Kunst AE Looman CW Mackenbach JP | 1993 | Am J Epidemiol1993，137，： | 1 |
| 16 | Endothelial progenitor cell dysfunction:a novel concept in the pathogenesis of vascular complications of type 1 diabetes显示文摘 | Loomans CJ de Koning EJ Staal FJ | 2004 | Diabetes2004，53，1： | 1 |
| 17 | Initiation of populationbased mammography screening in Dutch municipalities and effect on breast-cancer mortality:a systematic review显示文摘 | Otto SJ Fracheboud J Looman CW | 2003 | Lancet2003，361，9367： | 1 |
| 18 | Endothelial progenitor cell dysfunction:a novel concept in the pathogenesis of vascular complications of type 1 diabetes显示文摘 | Loomans C J de Koning E J Staal FJ | 2004 | Diabetes2004，53，1： | 1 |
| 19 | Intratumoral administration of recombinant human interleukin 12 in head and neck squamous cell carcinoma patients elicits a T-helper 1 profile in the locoregional lymph nodes显示文摘 | van Herpen CM Looman M Zonneveld M etal | 2004 | Clin Cancer Res2004，10，： | 1 |
| 20 | The management of paralytic spasticity显示文摘 | Herz DA Looman JE Tiberio A | 1990 | Neurosurgery1990，26，2： | 1 |
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