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| 1 | Antioxidant drugs to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis:What does evidence suggest?显示文摘AIM:To determine whether or not the use of antioxidant supplementation aids in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis.METHODS:A systematic review of randomized controlled trials(RCTs) was made to evaluate the preventive effect of prophylactic antioxidant supplementation in post-endoscopic retrograde cholangiopancreatography pancreatitis(PEP).The inclusion criteria included:acute post-endoscopic retrograde cholangiopancreatography pancreatitis in adults; randomized clinical trials with the use of any antioxidant as an intervention compared with placebo,to reduce PEP.The outcome measure was the incidence and severity of PEP.Twelve RCTs involving 3110 patients since 1999 wereincluded.The antioxidants used were selenite,β-carotene,and pentoxifylline(each one in one trial),N-acetylcysteine(NAC) in three trials,and allopurinol in six trials.The group of patients treated with NAC received different doses; either oral or intravenous,and allopurinol-treated patients received five different oral doses in two different administration periods.The results are expressed with raw numbers,proportions,as well as mean and standard deviations.The incidence of pancreatitis between groups was analyzed with Pearson's χ2 test or Fisher's exact test(F).The main outcome is expressed as relative risks and 95%CI.RESULTS:The incidence of pancreatitis in all antioxidant treatment groups was 8.6%,whereas it was 9.7% in the control group.The antioxidants used were selenite,β-carotene,and pentoxifylline(each one in one trial),NAC in three trials,and allopurinol in six trials.In allopurinol trials,three different dosifications were used; two trials reported a low dosage(of less than 400 mg),two trials reported a moderate dose(600 mg) and the remaining two employed higher doses(more than 900 mg).Supplementation was not associated with a significant reduction in the incidence of PEP [relative risk(RR) = 0.93; 95%CI:0.82-1.06; P = 0.28].In addition,the incidences of PEP in patients treated with allopurinol and those treated with other antioxidants were similar to that observed in patients who received the placebo(RR for trials with allopurinol,0.92; 95%CI:0.78-1.08; P = 0.31) and,with the use of other antioxidants,the incidence of PEP was 8.9%,whereas it was 9.7% in the control group(RR = 0.95; 95%CI:0.77-1.18; P = 0.19).CONCLUSION:Antioxidant supplementation shows no beneficial effect on the incidence of PEP.There is a lack of robust trials to support the use of antioxidants for prevention. | Clotilde Fuentes-Orozco Carlos Davalos-Cobian Jesus Garcia-Correa Gabriela Ambriz-Gonzalez Michel Dassaejv Macias-Amezcua Jesus Garcia-Renteria Jorge Rendon-Felix Mariana Chavez-Tostado Lizbeth Araceli Cuesta-Marquez Andrea Socorro Alvarez-Villasenor Ana Olivia Cortes-Flores Alejandro Gonzalez-Ojeda | 2015 | World Journal of Gastroenterology2015，21，21： | 6 |
| 2 | Gastric cancer in relation to the intake of nutrients involved in one-carbon metabolism among MTHFR 677 TT carriers显示文摘 | Marcia V. Galván-Portillo Alejandra Cantoral Luis F. O?ate-Oca?a Jia Chen Roberto Herrera-Goepfert Luisa Torres-Sanchez Raul U. Hernandez-Ramirez Oswaldo Palma-Coca Lizbeth López-Carrillo | 2009 | European Journal of Nutrition2009，，5： | 3 |
| 3 | Capsaicin consumption, Helicobacter pylori CagA status and IL1B-31C <ce:hsp sp='0.25'/>><ce:hsp sp='0.25'/> T genotypes: A host and environment interaction in gastric cancer显示文摘 | Lizbeth López-Carrillo M. Constanza Camargo Barbara G. Schneider Liviu A. Sicinschi Raúl U. Hernández-Ramírez Pelayo Correa Mariano E. Cebrian | 2012 | Food and Chemical Toxicology2012，，6： | 2 |
| 4 | An evaluation of Problem- based learning in a nursing theory and practicemodule显示文摘 | Lizbeth JB G eraldine L Tony B | 2002 | Nurse E- ducation in Practice2002，2，1： | 1 |
| 5 | Optimization of the ammonia fiber explosion (AFEX) treatment parameters for enzymatic hydrolysis of corn stover显示文摘 | Farzaneh Teymouri Lizbeth Laureano-Perez Hasan Alizadeh | 2005 | Bioresource Technology2005，96，18： | 1 |
| 6 | Insects as alternative feed for ruminants:comparison of protein evaluation methods显示文摘Background:The high dependence of intensive ruminant production on soybean meal and the environmental impact of this crop encourage the search for alternative protein-rich feeds.The use of insects seems promising,but the extent of their ruminal protein degradation is largely unknown.This parameter has major influence not only on N utilization efficiency but also on the environmental burden of ruminant farming.In addition,although assessing ruminal N degradation represents a key first step to examine the potential of new feeds,it is a challenging task due to the lack of a reference method.This study was conducted to investigate the potential of 4 insects(Tenebrio molitor,Zophobas morio,Alphitobius diaperinus and Acheta domesticus)as alternative protein sources for ruminants,using 3 methodologies:1)a regression technique based on the in vitro relationship between gas production and ammonia-N concentration;2)a conventional in vitro technique of batch cultures of ruminal microorganisms,based on filtering the incubation residue through sintered glass crucibles;and 3)the in situ nylon bag technique.The in vitro intestinal digestibility of the non-degraded protein in the rumen was also determined.Soybean meal was used as a reference feedstuff.Results:Comparison of evaluation methods(regression,in vitro and in situ)did not allow to reliably select a single value of ruminal N degradation for the studied substrates,but all techniques seem to establish a similar ranking,with good correlations between methods,particularly between regression and in situ results.Regardless of the methodology,nitrogen from the 4 insects(with contents ranging from 81 to 112 g/kg of dry matter)did not show high ruminal degradation(41–76%),this value being always lower than that of soybean meal.Furthermore,the in vitro intestinal digestibility of non-degraded N was relatively high in all feeds(≥64%).Conclusion:Overall,these results support the potential of the 4 studied insects as alternative feedstuffs for ruminants.Among them,T.molitor showed the lowest and greatest values of ruminal N degradation and intestinal digestibility,respectively,which would place it as probably the best option to replace dietary soybean meal and increase the sustainability of ruminant feeding. | Pablo G.Toral Gonzalo Hervás Mariana Gabriela González-Rosales Alejandro G.Mendoza Lizbeth E.Robles-Jiménez Pilar Frutos | 2022 | Journal of Animal Science and Biotechnology2022，13，4： | 1 |
| 7 | Optimization of the ammonia fiber explosion (AFEX) treatment parameters for enzymatic hydrolysis of corn stover 显示文摘 | Farzaneh Teymouri Lizbeth Laureano-Perez Hasan Alizadeh | 2005 | Bioresource Technology2005，96，18： | 1 |
| 8 | Exposure to Phthalates and Breast Cancer Risk in Northern Mexico显示文摘 | López-Carrillo Lizbeth Hernández-Ramírez Raúl U Calafat Antonia M Torres-Sánchez Luisa Galván-Portillo Marcia Needham Larry L Ruiz-Ramos Rubén Cebrián Mariano E | 2010 | Environmental Health Perspectives2010，，4： | 1 |
| 9 | ls rapid withdrawal of anti-epileptic drug therapy during video EEG monitoring safe and efficacious显示文摘 | Syed A A gizvi Lizbeth Hernandez--Ronquillo Adam Wu | | Epilepsy research0，4，108： | 1 |
| 10 | Serine protease mechanism and specificity 显示文摘 | Lizbeth Hedstrom | 2002 | Chemical Reviews2002，102，12： | 1 |
| 11 | Phthalate exposure associated with self-reported diabetes among Mexican women显示文摘 | Katherine Svensson Raúl U. Hernández-Ramírez Ana Burguete-García Mariano E. Cebrián Antonia M. Calafat Larry L. Needham Luz Claudio Lizbeth López-Carrillo | 2011 | Environmental Research2011，，6： | 1 |
| 12 | Inappropriate continuation of stress ulcer prophylactic therapy after discharge显示文摘 | Paul D Lizbeth A Hansen W | 2007 | Ann Pharmacother2007，41，10： | 1 |
| 13 | The Impact of Operat-ing in Multiple Value Chains for Upgrading : The Case of theBrazilian Furniture and Footwear Industries 显示文摘 | Lizbeth Navas - Alema’ N | 2011 | World De-velopment2011，39，8： | 1 |
| 14 | The Impact of Operating in Multiple Value Chains for Upgrading: The Case of the Brazilian Furniture and Footwear Industries显示文摘 | Lizbeth Navas-Alemán | 2011 | World Development2011，，8： | 1 |
| 15 | Serine Protease Mechanism and Specificity显示文摘 | Lizbeth Hedstrom | 2002 | Chem Rev2002，102，： | 1 |
| 16 | Dietary Patterns and Gastric Cancer Risk in Mexico显示文摘 | Edgar Denova-Gutiérrez RaúlU. Hernández-Ramírez Lizbeth López-Carrillo | 2014 | Nutrition and Cancer2014，，3： | 1 |
| 17 | Latctation and lead body burden turnover:A pilot study in Mexico显示文摘 | Jacqueline M Lizbeth LC Luisa TS | 2000 | J Occup Environ Med2000，42，11： | 1 |
| 18 | A1298C polymor-phism of the MTHFR gene and neural tube defects in the state of Yucatan,Mexico显示文摘 | Lizbeth Gonzalez-Herrera Ileana Castillo-Zapata | 2007 | Clinical and Molecular Teratology2007，79，8： | 1 |
| 19 | Prolonged postictal encephalopathy显示文摘 | Victor Biton John R. Gates Lizbeth dePadua Sussman | 1990 | Neurology1990，，6： | 1 |
| 20 | The Impact of Operating in Multiple Value Chains for Upgrading: The Case of the Brazilian Furni- ture and Footwear Industries 显示文摘 | Lizbeth Navas-Alema' N | 2011 | World Development2011，39，8： | 1 |
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