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| 1 | Applicability Assessment of the 1998–2018 CLDAS Multi-Source Precipitation Fusion Dataset over China显示文摘Traditional hourly rain gauges and automatic weather stations rarely measure solid precipitation, except for those stations with weighing-type precipitation sensors. Microwave remote sensing has only a low ability to retrieve solid precipitation. In addition, there are no long-term, high-quality precipitation data in China that can be used to drive land surface models. To address these issues, in the China Meteorological Administration(CMA) Land Data Assimilation System(CLDAS), we blended the Climate Prediction Center(CPC) morphing technique(CMORPH) and Modern-Era Retrospective analysis for Research and Applications version 2(MERRA2) precipitation datasets with observed temperature and precipitation data on various temporal scales using multigrid variational analysis and temporal downscaling to produce a multi-source precipitation fusion dataset for China(CLDAS-Prcp). This dataset covers all of China at a resolution of 6.25 km at hourly intervals from 1998 to 2018. We performed dependent and independent evaluations of the CLDAS-Prcp dataset from the perspectives of seasonal total precipitation and land surface model simulation. Our results show that the CLDAS-Prcp dataset represents reasonably the spatial distribution of precipitation in China. The dependent evaluation indicates that the CLDAS-Prcp performs better than the MERRA2 precipitation, CMORPH precipitation, Global Land Data Assimilation System version 2(GLDAS-V2.1) precipitation,and CLDAS-V2.0 winter precipitation, as compared to the meteorological observational precipitation. The independent evaluation indicates that the CLDAS-Prcp dataset performs better than the Global Precipitation Measurement(GPM) precipitation dataset and is similar to the CLDAS-V2.0 summer precipitation dataset based on the hydrological observational precipitation. The simulated soil moisture content driven by CLDAS-Prcp is slightly better than that driven by the CLDAS-V2.0 precipitation, whereas the snow depth simulation driven by CLDAS-Prcp is much better than that driven by the CLDAS-V2.0 precipitation. This is because the CLDAS-Prcp data have included solid precipitation. Overall, the CLDAS-Prcp dataset can meet the needs of land surface and hydrological modeling studies. | Shuai SUN Chunxiang SHI Yang PAN Lei BAI Bin XU Tao ZHANG Shuai HAN Lipeng JIANG | 2020 | Journal of Meteorological Research2020，34，4： | 7 |
| 2 | Evaluation of the chemical profile from four germplasms sources of Pruni Semen using UHPLC-LTQ-Orbitrap-MS and multivariate analyses显示文摘Pruni Semen,the seed of several unique Prunus plants,is a traditional purgative herbal material.To determine the authentic sources of Pruni Semen,46 samples from four species were collected and analyzed.Ten compounds including multiflorin A(Mul A),a notable purative compound,were isolated and identified by chemical separation and nuclear magnetic resonance spectroscopy.Seventy-six communal components were identified by ultra-high performance liquid chromatography with linear ion trap-quadrupole Orbitrap mass spectrometry,and acetyl flavonoid glycosides were recognized as characteristic constituents.The flavonoids were distributed in the seed coat and cyanogenic glycosides in the kernel.Based on this,methods for identifying Pruni Semen from different sources were established using chemical fingerprinting,quantitative analysis of the eight principal compounds,hierarchical cluster analysis,principal component analysis,and orthogonal partial least squares discriminant analysis.The results showed that the samples were divided into two categories:one is the small seeds from Prunus humilis(Ph)and Prunus japonica(Pj),and the other is the big seeds from Prunus pedunculata(Pp)and Prunus triloba(Pt).The average content of Mul A was 3.02,6.93,0.40,and 0.29 mg/g,while the average content of amygdalin was 18.5,17.7,31.5,and 30.9 mg/g in Ph,Pj,Pp,and Pt,respectively.All the above information suggests that small seeds might be superior sources of Pruni Semen.This is the first comprehensive report on the identification of chemical components in Pruni Semen from different species. | Zihan Zhao Yue Liu Yushi Zhang Zeyu Geng Rina Su Lipeng Zhou Chao Han Zhanjun Wang Shuangcheng Ma Weidong Li | 2022 | Journal of Pharmaceutical Analysis2022，12，5： | 1 |
| 3 | Personalized Learning Path Recommendations for Software Testing Courses Based on Knowledge Graphs显示文摘Software testing courses are characterized by strong practicality,comprehensiveness,and diversity.Due to the differences among students and the needs to design personalized solutions for their specific requirements,the design of the existing software testing courses fails to meet the demands for personalized learning.Knowledge graphs,with their rich semantics and good visualization effects,have a wide range of applications in the field of education.In response to the current problem of software testing courses which fails to meet the needs for personalized learning,this paper offers a learning path recommendation based on knowledge graphs to provide personalized learning paths for students. | Wei Zheng Ruonan Gu Xiaoxue Wu Lipeng Gao Han Li | 2023 | 计算机教育2023，，12： | 0 |
| 4 | An Experimental Study on Oxidized Mercury Adsorption by Bromide Blended Coal Combustion Fly Ash显示文摘The application of forced mercury oxidation technology would lead to an increase of Hg^(2+)concentration in the flue gas.Although Hg^(2+)can be easily removed in the WFGD,the mercury re-emission in the WFGD can decrease the total removal of mercury from coal-fired power plants.Hence,it is necessary to control Hg^(2+)concentration in the devices before the WFGD.Fly ash adsorbent is considered as a potential alternative for commercial activated carbon adsorbent.However,the adsorption efficiency of the original fly ash is low.Modification procedure is needed to enhance the adsorption performance.In this study,the adsorption of Hg^(2+)by brominated fly ash was studied.The fly ash was collected from the full-scale power plant utilizing bromide-blended coal combustion technology.The brominated fly ash exhibited excellent performance for Hg^(2+)removal.The flue gas component HBr and SO_(2)could improve adsorbent’s performance,while HCl would hinder its adsorption process.Also,it was demonstrated by Hg-TPD experiments that the adsorbed Hg^(2+)mainly existed on the fly ash surface in the form of HgBr_(2).In summary,the brominated fly ash has a broad application prospect for mercury control. | Mingyu Yu Mengyuan Liu Guangqian Luo Ruize Sun Jingyuan Hu Hailu Zhu Li Zhong Lipeng Han Xian Li Hong Yao | 2021 | Energy Engineering2021，118，5： | 0 |
| 5 | Synthesis of DNP-modified GM3-based anticancer vaccine and evaluation of its immunological activities for cancer immunotherapy显示文摘Tumor-associated carbohydrate antigens(TACAs) are attractive targets for vaccine development. In this context, we described a strategy combining artificial TACA and glycoengineering for cancer vaccine development. A 2,4-ditrophenyl(DNP)-modified GM3 intermediate was synthesized chemoenzymatically and conjugated to keyhole limpet hemocyanin(KLH), and the resulting bioconjugate was tested for its potential as a vaccine candidate. Mice immunological studies revealed that the DNP-modified GM3(GM3-NHDNP) analog elicited strong and rapid immune responses by recruiting anti-DNP antibodies to facilitate the targeted delivery of the vaccine construct to antigen processing cells(APCs). Moreover, the endogenously produced anti-DNP antibodies, together with the elicited antibodies against GM3-NHDNP, may synergistically promote tumor binding and cancer cell death when the cancer cell surfaces are glycoengineered to express the GM3-NHDNP antigen. | Han Lin Haofei Hong Lipeng Feng Jie Shi Zhifang Zhou Zhimeng Wu | 2021 | Chinese Chemical Letters2021，32，12： | 0 |
| 6 | An effective pharmacological hydrogel induces optic nerve repair and improves visual function显示文摘Irreversible eye lesions, such as glaucoma and traumatic optic neuropathy, can cause blindness;however, no effective treatments exist. The optic nerve, in particular, lacks the capacity to spontaneously regenerate, requiring the development of an effective approach for optic nerve repair, which has proven challenging. Here, we demonstrate that a combination of the small molecules 3BDO and trichostatin A(TSA)—which regulate mTOR and HDAC, respectively—packaged in thermosensitive hydrogel for 4-week-sustained release after intravitreal injection, effectively induced optic nerve regeneration in a mouse model of optic nerve crush injury. Moreover, this combination of 3BDO and TSA also protected axon projections and improved visual responses in an old mouse model(11 months old) of glaucoma. Taken together, our data provide a new, local small molecule-based treatment for the effective induction of optic nerve repair, which may represent a foundation for the development of pharmacological methods to treat irreversible eye diseases. | Lipeng Wang Shan Zhang Yawen Han Shuo Tang Jiarui Li Lina Bu Dongyu Zhao Hongkui Deng | 2024 | Science China(Life Sciences)2024，67，3： | 0 |
| 7 | Space/Air Covert Communications:Potentials,Scenarios,and Key Technologies显示文摘Space/air communications have been envisioned as an essential part of the next-generation mobile communication networks for providing highquality global connectivity. However, the inherent broadcasting nature of wireless propagation environment and the broad coverage pose severe threats to the protection of private data. Emerging covert communications provides a promising solution to achieve robust communication security. Aiming at facilitating the practical implementation of covert communications in space/air networks, we present a tutorial overview of its potentials, scenarios, and key technologies. Specifically, first, the commonly used covertness constraint model, covert performance metrics, and potential application scenarios are briefly introduced. Then, several efficient methods that introduce uncertainty into the covert system are thoroughly summarized, followed by several critical enabling technologies, including joint resource allocation and deployment/trajectory design, multi-antenna and beamforming techniques, reconfigurable intelligent surface(RIS), and artificial intelligence algorithms. Finally, we highlight some open issues for future investigation. | Mao Haobin Liu Yanming Zhu Lipeng Mao Tianqi Xiao Zhenyu Zhang Rui Han Zhu Xia Xianggen | 2024 | China Communications2024，21，3： | 0 |
| 8 | 3D Tungsten Trioxide Nanosheets as Optoelectronic Materials for On-chip Quantification of Global Antioxidant Capacity显示文摘The photoelectrochemical properties of semiconductors mainly depend on the size and shape of the corresponding nanoparticles.Herein,3D WO3 nanosheets were controllably synthesized with the aid of polyethyleneimine,which presents enhanced photocurrent responses.Based on this excellent photoelectrochemical property,a photoelectrochemical chip was prepared by lithography technology for the smart monitoring of the antioxidant capacity(AC)in red wine and exhibits a series of advantages including rapid response time,high sensitivity,and long-lasting stability.The mechanism of the present photoelectrochemical sensing was explored and shows a single electron transfer reaction.Furthermore,only 200µL of samples are required for one testing,which demonstrates that the present photoelectrochemical chip can be potentially integrated with a portable commercial device(such as a mobile phone)for further research and development of food and drug supervision. | DAI Mengjiao MA Weiguang HAN Fangjie HAN Dongfang HAN Lipeng WANG Wei ZHAO Bolin HAN Dongxue NIU Li WANG Zhenxin | 2021 | Chemical Research in Chinese Universities2021，37，3： | 0 |
| 9 | Functionalized Hierarchical ZSM-5 Zeolites for the Viscosity Reduction of Heavy Oil at Low Temperature显示文摘Herein,we propose a novel approach to reduce the viscosity of heavy oil by functional hierarchical CTMS-ZSM-5-PTMS zeolites.CTMS-ZSM-5-PTMS zeolites synthesized by asymmetric modification and selective alkali etching can reduce the viscosity of heavy oil through adsorbing asphaltenes.This method can reduce the viscosity of heavy oil from hundreds of thousands mPa·s to about ten thousand mPa·s.The work provides an economical and environmentally friendly candidate for heavy oil viscosity reduction under low-temperature conditions. | XIAO Peiwen LI Hui WANG Pingmei LIU Bolun JING Wendan HE Lipeng WANG Runwei HAN Xue ZHANG Zongtao QIU Shilun LUO Jianhui | 2022 | Chemical Research in Chinese Universities2022，38，4： | 0 |
| 10 | Serum procalcitonin levels are associated with rhabdomyolysis following exertional heatstroke: an over 10-year intensive care survey显示文摘BACKGROUND:Heatstroke has become a common emergency event in hospitals.Procalcitonin(PCT)is used as a biomarker of infection in the emergency department(ED),but its role in rhabdomyolysis(RM)following exertional heatstroke(EHS)remains unclear.METHODS:A retrospective cohort study enrolled patients with EHS from the intensive care unit(ICU).We collected RM biomarkers,inflammation markers,critical disease scores at admission,24 h,48 h,and discharge,and 90-day mortality.Correlation analysis,linear regression and curve fi tting were used to identify the relationship between PCT and RM.RESULTS:A total of 162 patients were recruited and divided into RM(n=56)and non-RM(n=106)groups.PCT was positively correlated with myoglobin(Mb),acute hepatic injury,disseminated intravascular coagulation(DIC),Sequential Organ Failure Assessment(SOFA)score,and Acute Physiology and Chronic Health Evaluation II(APACHE II)score,with correlation coefficients of 0.214,0.237,0.285,0.454,and 0.368,respectively(all P<0.05).Interestingly,the results of curve fi tting revealed a nonlinear relationship between PCT and RM,and a two-piecewise linear regression model showed that PCT was related to RM with an odds ratio of 1.3 and a cut-off of<4.6 ng/mL.Survival analysis revealed that RM was associated with higher mortality compared to non-RM cases(P=0.0093).CONCLUSION:High serum PCT concentrations are associated with RM after EHS in critically ill patients.Elevated PCT concentrations should be interpreted cautiously in patients with EHS in the ED. | Li Zhong Feifei Shuai Conglin Wang Lipeng Han Zhifeng Liu Ming Wu | 2024 | World Journal of Emergency Medicine2024，15，1： | 0 |
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