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| 1 | Groundwater quality and land use change in a typical karst agricultural region:a case study of Xiaojiang watershed,Yunnan显示文摘Taking the typical karst agricultural region, Xiaojiang watershed in Luxi of Yunnan Province as a research unit, utilizing the groundwater quality data in 1982 and 2004, the aerial photos in 1982 and TM images in 2004, supported by the GIS, we probe into the law and the reason of its space-time change of the groundwater quality over the past 22 years in the paper. The results show: (1) There were obvious temporal and spatial changes of groundwater quality during the past 22 years. (2) Concentrations of NH +4, 2? SO 4, NO 3?, NO 2?, Cl ?and the pH value, total hardness, total alkalinity increased significantly, in which + NH 4, NO 3?, and NO ?2of groundwater exceeded the drinking water standards as a result of non-point pollution caused by the expansion of cultivated land and mass use of the fertilizer and pesticide. (3) Oppositely, Ca2+ and HCO 3?showed an obvious decline trend due to forest reduction and degradation and stony desertification. Meantime, there was a dynamic relation between the groundwater quality change and the land use change. | JIANG Yongjun YUAN Daoxian XIE Shiyou LI Linli ZHANG Gui HE Raosheng | 2006 | Journal of Geographical Sciences2006，16，4： | 14 |
| 2 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 3 | Incremental value of contrast echocardiography in the diagnosis of left ventricular noncompaction显示文摘 | Xiaoxiao Zhang Li Yuan Linli Qiu Yali Yang Qing Lv Lin Li Jing Wang Lin He Li Zhang Xinfang Wang Mingxing Xie Xu Yu Jin | 2016 | Frontiers of Medicine2016，10，4： | 10 |
| 4 | Dephosphorylation of cardiomyocyte Cx43 is associated with myocardial ischemia and reperfusion injury显示文摘Objective:Myocardial ischemia/reperfusion(I/R) injury is the leading cause of death in the world. However,the details of the mechanism of its pathophysiology are still unknown. The present study was designed to investigate the role of connexin 43(Cx43) in acute models of myocardial I/R injury. Methods:Male C57BL/6 mice were subjected to myocardial ischemia(45 min) followed by reperfusion(4 hrs) in vivo. The whole operation was monitored using a two-lead ECG. Hearts were harvested and the level of protein was assessed by western blot analysis. Haematoxylin and Eosin(HE) staining was used to detect the extent of neutrophil infiltration. The expression level of IL-6 was detected by ELISA. Results:A murine myocardial I/R injury model was constructed successfully. Phosphorylated Cx43 decreased 83. 45% while non-phosphorylated Cx43 increased 1.62-fold in the myocardium after I/R injury. Neutrophil infiltration and the expression of the inflammatory cytokine IL-6 increased in the myocardium following I/R. Conclusion:During myocardial I/R injury,cardiomyocyte Cx43 is dephosphorylated,and this may be associated with an inflammatory response. | Zhijuan Cao Xuan Xu Linli Que Qi Chen Yuehua Li | 2009 | Journal of Nanjing Medical University2009，23，3： | 6 |
| 5 | Reinforcement learning with actor-critic for knowledge graph reasoning显示文摘Dear editor,In recent years,with the development of artificial intelligence and deep learning techniques,knowledge graph(KG)is receiving unprecedented attention.Essentially,KG is a semantic network,which stores massive information structured as entityrelation pairs in a graphical model. | Linli ZHANG Dewei LI Yugeng XI Shuai JIA | 2020 | Science China(Information Sciences)2020，63，6： | 4 |
| 6 | Electromagnetic-Thermo-Mechanical Coupling Behavior of Cu/Si Layered Thin Plate Under Pulsed Magnetic Field显示文摘Semiconductor-based electronic devices usually work under multiphysics fields rendering complex electromagnetic-thermo-mechanical coupling.In this work,we develop a penalty function method based on a finite element analysis to tackle this coupling behavior in a metal/semiconductor bilayer plate-the representative unit of semiconductor antenna,which receives strong and pulsed electromagnetic signals.Under these pulses,eddy current is generated,of which the magnitude varies remarkably from one plate to another due to the difference in electrical conductivity.In the concerned system,the metal layer generates much larger current,resulting in the large temperature rise and the nonnegligible Lorentz force,which could lead to delamination and failure of the semiconductor-based electronic device.This study provides theoretical guidance for the design and protection of semiconductor-based electronic devices in complex environments. | Qicong Li Linli Zhu Haihui Ruan | 2022 | Acta Mechanica Solida Sinica2022，35，1： | 2 |
| 7 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 8 | TIR/BB-loop mimetic AS-1 protects vascular endothelial cells from injury induced by hypoxia/reoxygenation显示文摘Morphological and functional abnormalities of vascular endothelial cells(VECs) are risk factors of ischemiareperfusion in skin flaps.Signaling pathway mediated by interleukin-1 receptor(IL-1 R) is essential to hypoxia/reoxygenation(H/R) injury of VECs.While the TIR/BB-loop mimetic(AS-1) disrupts the interaction between IL-1 R and myeloid differentiation primary-response protein 88(MyD88),its role in the VECs dysfunction under H/R is unclear.In this study,we first showed that there was an infiltration of inflammatory cells and the apoptosis of VECs by using a skin flap section from patients who received flap transplantation.We then showed that the H/R treatment induced apoptosis and loss of cell migration of endothelial cell line H926 were attenuated by AS-1.Furthermore,our data suggested that AS-1 inhibits the interaction between IL-1 R and MyD88,and subsequent phosphorylation of IκB and p38 pathway,as well as the nuclear localization of NF-κB subunit p65/p50.Thus,this study indicated that the protective role of AS-1 in H/R induced cellular injury may be due to the AS-1 mediated down-regulation of IL-1 R signaling pathway. | Zhijia Zhang Yuxing Hou Jiantao Li Chao Tang Linli Que Qian Tan Yuehua Li | 2020 | The Journal of Biomedical Research2020，34，5： | 2 |
| 9 | Existence and stability of periodic solution for impulsive Hopfield cellular neural net-works with time delays显示文摘 | Zhang Linli Liu Anping Xiao Li | | 0，，01： | 1 |
| 10 | Effect of Stress-Dependent Thermal Conductivity on Thermo-Mechanical Coupling Behavior in GaN-Based Nanofilm Under Pulse Heat Source显示文摘The thermal properties of a nanostructured semiconductor are affected by multi-physical fields,such as stress and electromagnetic fields,causing changes in temperature and strain distributions.In this work,the influence of stress-dependent thermal conductivity on the heat transfer behavior of a GaN-based nanofilm is investigated.The finite element method is adopted to simulate the temperature distribution in a prestressed nanofilm under heat pulses.Numerical results demonstrate the effect of stress field on the thermal conductivity of GaN-based nanofilm,namely,the prestress and the thermal stress lead to a change in the heat transfer behavior in the nanofilm.Under the same heat source,the peak temperature of the film with stress-dependent thermal conductivity is significantly lower than that of the film with a constant thermal conductivity and the maximum temperature difference can reach 8.2 K.These results could be useful for designing GaN-based semiconductor devices with higher reliability under multi-physical fields. | Qicong Li Xiaoya Tang Linli Zhu Haihui Ruan | 2021 | Acta Mechanica Solida Sinica2021，34，1： | 1 |
| 11 | Modeling hydrological responses of karst spring to storm events: example of the Shuifang spring (Jinfo Mt., Chongqing, China)显示文摘 | Yuexia Wu Yongjun Jiang Daoxian Yuan Linli Li | 2008 | Environmental Geology2008，，7： | 1 |
| 12 | Non opera- tion treatment of tramnatic hepatic rupture factors analysis 显示文摘 | Li Linli Zhang generation field Raymond Lam | 2011 | Chinese medicine science2011，27，46： | 1 |
| 13 | A new coumarin glycoside from the husks of Xanthoceras sorbifolia显示文摘 | ZHAN Linli XIAN Li DAN Yili | 2007 | Fitoterapia2007，78，： | 1 |
| 14 | Optically-generated focused ultrasound for noninvasive brain stimulation with ultrahigh precision显示文摘High precision neuromodulation is a powerful tool to decipher neurocircuits and treat neurological diseases.Current non-invasive neuromodulation methods offer limited precision at the milimeter level.Here,we report opticallygenerated focused ultrasound(OFUS)for non-invasive brain stimulation with ultrahigh precision.OFUS is generated by a soft optoacoustic pad(SOAP)fabricated through embedding candle soot nanoparticles in a curved polydimethylsiloxane film.SOAP generates a transcranial ultrasound focus at 15 MHz with an ultrahigh lateral resolution of 83μm,which is two orders of magnitude smaller than that of conventional transcranial-focused ultrasound(tFUS).Here,we show effective OFUS neurostimulation in vitro with a single ultrasound cycle.We demonstrate submillimeter transcranial stimulation of the mouse motor cortex in vivo.An acoustic energy of 0.6 mJ/cm?,four orders of magnitude less than that of tFUS,is suffcient for successful OFUS neurostimulation.OFUS offers new capabilities for neuroscience studies and disease treatments by delivering a focus with ultrahigh precision noninvasively. | Yueming Li Ying Jiang Lu Lan Xiaowei Ge Ran Cheng Yuewei Zhan Guo Chen Linli Shi Runyu Wang Nan Zheng Chen Yang Ji-Xin Cheng | 2022 | Light(Science & Applications)2022，11，11： | 1 |
| 15 | Integrin β3 and its ligand regulate the expression of uPA through p38 MAPK in breast cancer显示文摘 | RUIWANG ZHAO‐QINGLI XUHAN BAI‐LINLI XIAO‐YIMI LI‐MEISUN MINSONG YAN‐CHUNHAN YANZHAO EN‐HUAWANG | 2010 | APMIS2010，，12： | 1 |
| 16 | The Variability of Air-sea O_(2)Flux in CMIP6:Implications for Estimating Terrestrial and Oceanic Carbon Sinks显示文摘The measurement of atmospheric O_(2)concentrations and related oxygen budget have been used to estimate terrestrial and oceanic carbon uptake.However,a discrepancy remains in assessments of O_(2)exchange between ocean and atmosphere(i.e.air-sea O_(2)flux),which is one of the major contributors to uncertainties in the O_(2)-based estimations of the carbon uptake.Here,we explore the variability of air-sea O_(2)flux with the use of outputs from Coupled Model Intercomparison Project phase 6(CMIP6).The simulated air-sea O_(2)flux exhibits an obvious warming-induced upward trend(~1.49 Tmol yr−2)since the mid-1980s,accompanied by a strong decadal variability dominated by oceanic climate modes.We subsequently revise the O_(2)-based carbon uptakes in response to this changing air-sea O_(2)flux.Our results show that,for the 1990−2000 period,the averaged net ocean and land sinks are 2.10±0.43 and 1.14±0.52 GtC yr−1 respectively,overall consistent with estimates derived by the Global Carbon Project(GCP).An enhanced carbon uptake is found in both land and ocean after year 2000,reflecting the modification of carbon cycle under human activities.Results derived from CMIP5 simulations also investigated in the study allow for comparisons from which we can see the vital importance of oxygen dataset on carbon uptake estimations. | Changyu LI Jianping HUANG Lei DING Yu REN Linli AN Xiaoyue LIU Jiping HUANG | 2022 | Advances in Atmospheric Sciences2022，39，8： | 1 |
| 17 | MiR-203 is downregulated in laryngeal squamous cell carcinoma and can suppress proliferation and induce apoptosis of tumours显示文摘 | Linli Tian Minghua Li Jingchun Ge Yan Guo Yanan Sun Ming Liu Hui Xiao | 2014 | Tumor Biology2014，，6： | 1 |
| 18 | Dissecting active in- gredients of Chinese medicine by content-weighted ingredi- ent-target network显示文摘 | Linli Wang Zheng Li Qing Shao | 2014 | Mol Biosyst2014，10，： | 1 |
| 19 | The best utilization of D. zingiberensis C.H. Wright by an eco-friendly process显示文摘 | Wen Huang Huazhang Zhao Jinren Ni Hang Zuo Linli Qiu Hua Li Hui Li | 2008 | Bioresource Technology2008，，15： | 1 |
| 20 | Synthesis, Characterization of Star-Shaped Analogue with Benzene Core and Three Naphthalene Diimide Side-Arms显示文摘有 diimide (NDI ) 方面武装的苯核心和三萘的二个塑造星的分子被二拍子的圆舞 imidization 反应轻易地从 1,4,5,8-naphthalenetetracarboxylic dianhydride 准备。二混合物象 NDI 一样给类似的紫外力的吸收乐队看了。他们在答案与那相比在电影显示了他们的紫外力的吸收和排放系列的 bathochromic 移动,这被发现,归功于到在处于稳固的状态的分子之间的聚集。可逆减小过程被周期的 voltammetry 和精力铺平的低躺 LUMO 观察(为 1a 的 −3.83 eV,为 1b 的 −3.87 eV ) 被推出,它建议这二混合物拥有了好电子领受人性质并且能被用作潜在的 n 类型材料。 | Linli Hu Jinling Li Jie Huang Jun Yin | 2017 | Chinese Journal of Chemistry2017，35，1： | 1 |
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