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| 1 | A Novel QTL qTGW3 Encodes the GSK3/ SHAGGY-Like Kinase OsGSK5/OsSK41 that Interacts with OsARF4 to Negatively Regulate Grain Size and Weight in Rice显示文摘谷物尺寸和形状在米饭是谷物重量和产量的重要决定因素。这里,我们报导一个新主要量的特点在米饭的地点(QTL ) , qTGW3,那种控制谷物尺寸和重量。这个地点, qTGW3,编码 OsSK41 (也作为 OsGSK5 知道) , GLYCOGEN SYNTHASE KINASE 3/SHAGGY-like 家庭的一个成员。带 OsSK41 的 loss-of-function 等位基因的瑞斯 near-isogenic 线增加了谷物长度和重量。我们证明那 OsSK41 交往与并且 phosphorylates 植物生长素反应因素 4 (OsARF4 ) 。有 OsARF4 的 OsSK41 的合作表示在米饭原物增加 OsARF4 的累积。OsARF4 的功能的损失导致更大的米饭谷物。定序 RNA 分析建议 OsARF4 和 OsSK41 镇压下游的基因的一个普通集合的表示, ? 包括一些植物生长素应答的基因,在米饭谷物开发期间。在 qTGW3 的 OsSK41 的 loss-of-function 形式代表没被指向的基因编辑或 QTL 节节上升广泛地在 OsSK41 功能的米饭 breeding.?Suppression 利用了的稀罕等位基因提高米饭谷物尺寸和重量。因此,我们的学习在米饭谷物开发揭示 OsSK41 的重要角色 ?? 并且在另外的谷物庄稼在米饭并且也许为谷物产量的基因改进提供新候选人基因。 | Zejun Hu Sun-Jie Lu Mei-Jing Wang Haohua He Le Sun Hongru Wang Xue-Huan Liu Ling Jiang Jing-Liang sun Xiaoyun Xin Wei Kong Chengcai Chu Hong-Wei Xue Jinshui Yang Xiaojin Luo Jian-Xiang Liu | 2018 | Molecular Plant2018，11，5： | 47 |
| 2 | Conservation of IRE1-Regulated bZIP74 mRNA Unconventional Splicing in Rice (Oryza sativa L.) Involved in ER Stress Responses显示文摘在 endoplasmic 蜂窝胃合拢的蛋白质(嗯) 是在对许多环境压力脆弱的植物房间的一个基本过程。当展开时或错误褶层蛋白质在 ER,积累保存得好的展开的蛋白质反应(UPR ) 被开始由提高合拢能力或加速嗯联系蛋白质降级的蛋白质减轻 ER 压力。这里,我们报导 OsbZIP74 的激活机制的保存(也作为 OsbZIP50 知道) ,一重要嗯在 monocot 植物米饭(Oryza sativa L.) 的压力管理者。在正常条件下面, OsbZIP74 mRNA 与一个通常认为的 transmembrane 领域编码一个基本 leucinezipper 抄写因素。当对待与时嗯导致压力的代理人象 tunicamycin 和 DTT 那样, OsbZIP74 mRNA 的保存双茎环结构外面被拼接。此后,结果新 OsbZIP74 mRNA 生产 OsbZIP74 蛋白质的原子核局部性的形式,消除恐水病的区域。OsbZIP74 的激活的形式在酵母房间和 Arabidopsis 叶原物举办 transcriptional 激活活动。拼接的 OsbZIP74 的正式就职是在 OsIRE1 击倒的米饭植物压制的大部分,显示在拼接的 OsbZIP74 的 OsIRE1 的参与。我们也证明 OsbZIP74 mRNA 的异乎寻常的拼接与热应力和水杨酸酸被联系,它是在对病原体或寄生虫的全身的获得的抵抗的重要植物荷尔蒙。 | Sun-Jie Lu Zheng-Ting Yang Ling Sun Le Sun Ze-Ting Song Jian-Xiang Li | 2012 | Molecular Plant2012，5，2： | 28 |
| 3 | Expenditure and financial burden for the diagnosis and treatment of colorectal cancer in China:a hospital.based,multicenter,cross-sectional survey显示文摘Background: The increasing prevalence of colorectal cancer(CRC) in China and the paucity of information about relevant expenditure highlight the necessity of better understanding the financial burden and effect of CRC diagnosis and treatment. We performed a survey to quantify the direct medical and non-medical expenditure as well as the resulting financial burden of CRC patients in China.Methods: We conducted a multicenter, cross-sectional survey in 37 tertiary hospitals in 13 provinces across China between 2012 and 2014. Each enrolled patient was interviewed using a structured questionnaire. All expenditure data were inflated to the 2014 Chinese Yuan(CNY; 1 CNY = 0.163 USD). We quantified the overall expenditure and financial burden and by subgroup(hospital type, age at diagnosis, sex, education, occupation, insurance type, household income, clinical stage, pathologic type, and therapeutic regimen). We then performed generalized linear modeling to determine the factors associated with overall expenditure.Results: A total of 2356 patients with a mean age of 57.4 years were included, 57.1 % of whom were men; 13.9% of patients had stage I cancer; and the average previous-year household income was 54,525 CNY.The overall average direct expenditure per patient was estimated to be 67,408 CNY, and the expenditures for stage Ⅰ, Ⅱ, Ⅲ, and Ⅳ disease were 56,099 CNY, 59,952 CNY, 67,292 CNY, and 82,729 CNY, respectively. Non-medical expenditure accounted for 8.3%of the overall expenditure. The 1-year out-of-pocket expenditure of a newly diagnosed patient was 32,649 CNY, which accounted for 59.9% of their previous-year household income and caused 75.0% of families to suffer an unmanageable financial burden. Univariate analysis showed that financial burden and overall expenditure differed in almost all subgroups(P < 0.05), except for sex. Multivariate analysis showed that patients who were treated in specialized hospitals and those who were diagnosed with adenocarcinoma or diagnosed at a later stage were likely to spend more,whereas those with a lower household income and those who underwent surgery spent less(all P < 0.05).Conclusions: For patients in China, direct expenditure for the diagnosis and treatment of CRC seemed catastrophic,and non-medical expenditure was non-ignorable. The financial burden varied among subgroups, especially among patients with different clinical stages of disease, which suggests that, in China, CRC screening might be cost-effective. | Hui-Yao Huang Ju-Fang Shi Lan-Wei Guo Ya-Na Bai Xian-Zhen Liao Guo-iangLiu A-Yan Mao Jian-Song Ren Xiao-Jie Sun Xin-Yu Zhu Le Wang Bing-Bing Song Ling-Bin Du Lin Zhu Ji-Yong Gong Qi Zhou Yu-Qin Liu Rong Cao Ling Mai Li Lan Xiao-Hua Sun Ying Ren Jin-Yi Zhou Yuan-Zheng Wang Xiao Qi Pei-An Lou Dian Shi Ni Li Kai Zhang Jie He Min Dai | 2017 | Chinese Journal of Cancer2017，36，8： | 25 |
| 4 | Performances evaluation of four typical unmanned aerial vehicles used for pesticide application in China显示文摘In recent years,unmanned aerial vehicles(UAVs)for plant protection have achieved rapid development in China.In order to test and evaluate the performances of pesticides application and development status of UAVs in China,four typical UAV models were selected to test the spraying coverage,penetrability,droplets density and the work efficiency.The results showed that the deposition and spraying liquid coverage were inconsistent both in lateral and longitudinal direction.Under the condition of the similar amount of spray volume and operation parameters,the volume median diameter(VMD)of the droplet was negatively correlated with the coverage density.The failure of the UAVs for plant protection mainly took up on the blockage of nozzle,transfusion tube and the liquid pump.The failure rate of UAVs took up 3.73%-4.36%of the total working time.The operation of UAVs during ground service took up 50%of the total working time,the preparation work took up 10%,and the route planning took up around 10%,while net operation time only took up around 30%.On the whole,the high efficiency of UAV was not fully achieved;the daily operated area was not in a satisfactory level now.The spraying performances of UAVs still need further improvement. | Wang Shilin Song Jianli He Xiongkui Song Le Wang Xiaonan Wang Changling Wang Zhichong Ling Yun | 2017 | International Journal of Agricultural and Biological Engineering2017，10，4： | 25 |
| 5 | Endothelial Nitric Oxide Synthase Gene Intron 4, 27 bp Repeat Polymorphism and Essential Hypertension in the Kazakh Chinese Population显示文摘为了调查在 27 bp 之间的关系,在内含子 4in 重复多型性 endothelial 在 KazakhChinese 人口的氮的氧化物合酶( eNOS4 )基因和必要高血压,有必要高血压和 138 个健康的人的 151 个病人在 Xinjiang uygur 从 Shawan 区域的 Boertonggu 农村被选择中国 in2006 的自治区域。在二个组的 eNOS 的多型性与聚合酶链反应试金被检测,在每个组的遗传型频率是计算的跟随 Hardy-Weinberg 法律。Fourand 27 bp 重复的五辆双人脚踏车是被指明一 and “ b' 分别地。b/b, b/a 和 eNOS4 基因的 a/a 遗传型的频率在控制组是 84.06% , 15.22% 和 0.72% ,这被发现,并且 81.46% , 15.89% 和 2.65% 分别地在高血压组织。基因的频率一 and “ b' 在控制组是 91.67% 和 8.33% , 89.40% 和 10.60% 分别地在高血压组织。血浆 eNOS 活动没与 eNOS 基因的遗传型和等位基因被联系,这被发现。在高血压组的血浆 eNOS 活动显著地与控制组(P<0.01 ) 相比被减少。结果建议 eNOS4 基因多型性是不大可能的是为在 Xinjiang 哈萨克人口的必要高血压的主要基因危险性因素。然而,在血浆 eNOS 活动之间的一个积极协会和必要高血压被揭示了。 | Fengmei DENG Qinghua HU Bin TANG Fang HE Shuxia GUO Jiang CHEN Feng LI Xuehua WU Jun ZHANG Huimin ZHANG Juan ZHAO Hua ZHONG Ling HE Jun LI Le ZHANG Shuren WANG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，5： | 18 |
| 6 | The Lumen-Facing Domain Is Important for the Biological Function and Organelle-to-Organelle Movement of bZIP28 during ER Stress in Arabidopsis显示文摘联系膜的抄写因素, bZIP28,从 endoplasmic 蜂窝胃被重定位(嗯) 免除了到 Golgi 并且解朊地膜由二朊酶, S1P 和 S2P 调停了,响应嗯在 Arabidopsis 的应力。激活的 N 终端领域成员在原子核的原子因素 Y (NF-Y ) 子单元调整嗯强调下游的基因。很少对 bZIP28 C 终端面对腔的域的函数被知道。这里,我们提供 ER 面对腔的领域怎么在 ER 压力反应影响生物功能和 bZIP28 的 organelle-to-organelle 运动的新奇卓见。首先,我们由 bZIP28 和 bZIP60 的产生和分析表明了 bZIP28 和 bZIP60 的功能的冗余性两倍变异的 zip28zip60。在有 bZIP28 上的删除的 zip28zip60 背景的随后的基因互补实验面对腔的领域强调了面对腔的领域的重要性为它的在里面在 ER 压力反应的 bZIP28 的 vivo 功能。蛋白质 subcellular 本地化和西方的弄污结果进一步表明面对腔的领域包含的 bZIP28 嗯为 bZIP28 的解朊的激活重要的保留信号。因此,面对腔的 C 终点玩的 bZIP28 在 bZIP28 的 ER-to-Golgi 运动的重要角色,它可以贡献察觉到 ER 强调。 | Le Sun Sun-Jie Lu Shuang-Shuang Zhang Shun-Fan Zhou Ling Sun Jian-Xiang Liu | 2013 | Molecular Plant2013，6，5： | 15 |
| 7 | Simultaneous incorporation of PTH(1-34) and nano-hydroxyapatite into Chitosan/Alginate Hydrogels for efficient bone regeneration显示文摘Tissue regeneration based on the utilization of artificial soft materials is considered a promising treatment for bone-related diseases.Here,we report cranial bone regeneration promoted by hydrogels that contain parathyroid hormone(PTH)peptide PTH(1-34)and nano-hydroxyapatite(nHAP).A combination of the positively charged natural polymer chitosan(CS)and negatively charged sodium alginate led to the formation of hydrogels with porous structures,as shown by scanning electron microscopy.Rheological characterizations revealed that the mechanical properties of the hydrogels were almost maintained upon the addition of nHAP and PTH(1-34).In vitro experiments showed that the hydrogel containing nHAP and PTH(1-34)exhibited strong biocompatibility and facilitated osteogenic differentiation of rat bone marrow mesenchymal stem cells(rBMSCs)via the Notch signaling pathway,as shown by the upregulated expression of osteogenic-related proteins.We found that increasing the content of PTH(1-34)in the hydrogels resulted in enhanced osteogenic differentiation of BMSCs.Implantation of the complex hydrogel into a rat cranial defect model led to efficient bone regeneration compared to the rats treated with the hydrogel alone or with nHAP,indicating the simultaneous therapeutic effect of nHAP and PTH during the treatment process.Both the in vitro and in vivo results demonstrated that simultaneously incorporating nHAP and PTH into hydrogels shows promise for bone regeneration,suggesting a new strategy for tissue engineering and regeneration in the future. | Zhiyuan Zou Le Wang Zhifei Zhou Qing Sun Delong Liu Yan Chen Hao Hu Yu Cai Sixiong Lin Zhengran Yu Bizhi Tan Wei Guo Zemin Ling Xuenong Zou | 2021 | Bioactive Materials2021，6，6： | 7 |
| 8 | Novel lignans from the stems and leaves of Trachelospermum jasminoides显示文摘5-methoxydibenzylhydroxybutyrolactone lignans 说出 5-methoxytracheloside 和 5-methoxytrachelogenin 的二篇小说从 Trachelospermum jasminoides ( Lindl )的茎和叶子被孤立 Lem ,他们的结构是被决定( 8S , 8S )-8-hydroxy-3, 3 , 4 , 5-tertramethoxylignan-9 , 9-olide-4-O--d-glucopyranoside 并且( 8S , 8S )-4, 8-dihydroxy-3 , 3 , 4 , 5-tertramethoxylignan-9 ,由各种各样的分光镜的分析的 9-olide 。5-Methoxytracheloside 是新混合物, 5-methoxytrachelogenin 第一次从生来的来源被孤立。 | Ling Jing Neng Jiang Yu Yu Shan Li Le Fu Yi Min Zhao | 2011 | Chinese Chemical Letters2011，22，9： | 5 |
| 9 | Synergistic effects of magnesium ions and simvastatin on attenuation of high-fat diet-induced bone loss显示文摘Introduction:Magnesium(Mg)has a prophylactic potential against the onset of hyperlipidemia.Similar to statin,Mg is recommended as lipid-lowering medication for hypercholesterolemia and concomitantly exhibits an association with increased bone mass.The combination of statin with Mg ions(Mg^(2+))may be able to alleviate the high-fat diet(HFD)-induced bone loss and reduce the side-effects of statin.This study aimed to explore the feasibility of combined Mg^(2+)with simvastatin(SIM)for treating HFD-induced bone loss in mice and the involving mechanisms.Materials and methods:C57BL/6 male mice were fed with a HFD or a normal-fat diet(NFD).Mice were intraperitoneally injected SIM and/or orally received water with additional Mg^(2+)until sacrificed.Enzyme-linked immunosorbent assay was performed to measure cytokines and cholesterol in serum and liver lysates.Bone mineral density(BMD)and microarchitecture were assessed by micro-computed tomography(μCT)in different groups.The adipogenesis in palmitate pre-treated HepG2 cells was performed under various treatments.Results:μCT analysis showed that the trabecular bone mass was significantly lower in the HFD-fed group than that in NFD-fed group since week 8.The cortical thickness in HFD-fed group had a significant decrease at week 24,as compared with NFD-fed group.The combination of Mg^(2+)and SIM significantly attenuated the trabecular bone loss in HFD-fed mice via arresting the osteoclast formation and bone resorption.Besides,such combination also reduced the hepatocytic synthesis of cholesterol and inhibited matrix metallopeptidase 13(Mmp13)mRNA expression in pre-osteoclasts.Conclusions:The combination of Mg^(2+)and SIM shows a synergistic effect on attenuating the HFD-induced bone loss.Our current formulation may be a cost-effective alternative treatment to be indicated for obesity-related bone loss. | Bingyang Dai Xu Li Jiankun Xu Yuwei Zhu Le Huang Wenxue Tong Hao Yao Dick Ho-kiu Chow Ling Qin | 2021 | Bioactive Materials2021，6，8： | 4 |
| 10 | Blockchain-enabled wireless communications:a new paradigm towards 6G显示文摘With the deployment of fifth-generation(5 G)wireless networks worldwide,research on sixth-generation(6 G)wireless communications has commenced.It is expected that 6 G networks can accommodate numerous heterogeneous devices and infrastructures with enhanced efficiency and security over diverse,e.g.spectrum,computing and storage,resources.However,this goal is impeded by a number of trust-related issues that are often neglected in network designs.Blockchain,as an innovative and revolutionary technology that has arisen in the recent decade,provides a promising solution.Building on its nature of decentralization,transparency,anonymity,immutability,traceability and resiliency,blockchain can establish cooperative trust among separate network entities and facilitate,e.g.efficient resource sharing,trusted data interaction,secure access control,privacy protection,and tracing,certification and supervision functionalities for wireless networks,thus presenting a new paradigm towards 6 G.This paper is dedicated to blockchain-enabled wireless communication technologies.We first provide a brief introduction to the fundamentals of blockchain,and then we conduct a comprehensive investigation of the most recent efforts in incorporating blockchain into wireless communications from several aspects.Importantly,we further propose a unified framework of the blockchain radio access network(B-RAN)as a trustworthy and secure paradigm for 6 G networking by utilizing blockchain technologies with enhanced efficiency and security.The critical elements of B-RAN,such as consensus mechanisms,smart contract,trustworthy access,mathematical modeling,cross-network sharing,data tracking and auditing and intelligent networking,are elaborated.We also provide the prototype design of B-RAN along with the latest experimental results. | Jiaheng Wang Xintong Ling Yuwei Le Yongming Huang Xiaohu You | 2021 | National Science Review2021，8，9： | 4 |
| 11 | Biodegradable magnesium pins enhanced the healing of transverse patellar fracture in rabbits显示文摘Displaced fractures of patella often require open reduction surgery and internal fixation to restore the extensor continuity and articular congruity.Fracture fixation with biodegradable magnesium(Mg)pins enhanced fracture healing.We hypothesized that fixation with Mg pins and their degradation over time would enhance healing of patellar fracture radiologically,mechanically,and histologically.Transverse patellar fracture surgery was performed on thirty-two 18-weeks old female New Zealand White Rabbits.The fracture was fixed with a pin made of stainless steel or pure Mg,and a figure-of-eight stainless steel band wire.Samples were harvested at week 8 or 12,and assessed with microCT,tensile testing,microindentation,and histology.Microarchitectural analysis showed that Mg group showed 12%higher in the ratio of bone volume to tissue volume at week 8,and 38.4%higher of bone volume at week 12.Tensile testing showed that the failure load and stiffness of Mg group were 66.9%and 104%higher than the control group at week 8,respectively.At week 12,Mg group was 60.8%higher in ultimate strength than the control group.Microindentation showed that,compared to the Control group,Mg group showed 49.9%higher Vickers hardness and 31%higher elastic modulus at week 8 and 12,respectively.At week 12,the new bone of Mg group remodelled to laminar bone,but those of the control group remained woven bone-like.Fixation of transverse patellar fracture with Mg pins and its degradation enhanced new bone formation and mechanical properties of the repaired patella compared to the Control group. | Dick Ho Kiu Chow Jiali Wang Peng Wan Lizhen Zheng Michael Tim Yun Ong Le Huang Wenxue Tong Lili Tan Ke Yang Ling Qin | 2021 | Bioactive Materials2021，6，11： | 3 |
| 12 | Cross-Scale Synthesis of Organic High-k Semiconductors Based on Spiro-Gridized Nanopolymers显示文摘High dielectric constants in organic semiconductors have been identified as a central challenge for the improvement in not only piexoelectric,preolecric,and freeltric efcts but also photoclecric conversion eficiency in OPVs,carrier mobility in OFETS,and charge density in charge-trapping memories.Herein,we report an ultralong persistence length(≈41 nm)efet of spiro-fused organic nanopolymers on dielectric properties,together with excitonic and charge carrier behaviors.The state-of-the-art nanopolymers,namely,nanopolyspirogrids(NPSGs),are synthesized via the simple crossscale Friedel-Crafts polygridlization of AjB-type nanomonomers.The high dielectric constant(k=8.43)of NPSG is firstly achieved by locking spiro-polygridization efect that results in the enhancement of dipole polarization.When doping into a polystyrene-based dielectric layer,such a high-k feature of NPSG increases the feld-ffct carrier mobility from 0.20 to 0.90cm^(2)Vl s'in pentacene OFET devices.Meanwhile,amorphous NPSG film exhibits an ultralow energy disorder(<50 meV)for an exellent zero-field hole mobility of 3.94×10^(-1)cm^(2)V^(-1)s^(-1).surpassing most of the amorphousπconjugated polymers Onganic nanopolymers with high dielectric constants open a new way to break through the bottleneck of eficiency and multifunctionality in the blueprint of the fourth generation semiconductors. | Dongqing Lin Wenhua Zhang Hang Yin Haixia Hu Yang Li He Zhang Le Wang Xinmiao Xie Hongkai Hu Yongxia Yan Haifeng Ling Jin'an Liu Yue Qian Lei Tang Yongxia Wang Chaoyang Dong Linghai Xie Hao Zhang Shasha Wang Ying Wei Xuefeng Guo Dan Lu Wei Huang | 2022 | Research2022，，2： | 3 |
| 13 | Optimization of Technology for Increasing Total Ester Content of Jujube Wine by Adding Nutrients显示文摘Using jujube juice prepared from red jujube as raw material and Saccharomyces cerevisiae as experimental strain,the effect of nutrients on the content of total ester in jujube wine was studied. The nutrients affecting the total ester content of jujube wine were glutamine,arginine,calcium chloride and biotin by Plackett-Burman design. Through the steepest ascent test,it was determined that the central points of the optimum addition of nutrients were glutamine 40 mg/L,arginine 50 mg/L,calcium chloride 35 mg/L and biotin 0. 25 mg/L,respectively.Through Box-Behnken experiment design,taking glutamine,arginine,calcium chloride and biotin as experimental factors,and the content of total ester in jujube wine as response value,the response surface optimization experiment was carried out and the verification experiment was also carried out. It was found that the response surface model can be used to predict the total ester content of jujube wine when nutritional elements were added. When the content of total ester in jujube wine was the highest,the optimal combination of nutrients was glutamine38. 8 mg/L,arginine 53. 8 mg/L,calcium chloride 35. 7 mg/L and biotin 0. 3 mg/L. At this point,the content of total ester in jujube wine was 628 mg/L,which was very close to the predicted value. Through the sensory evaluation of jujube wine,it was found that adding nutrients could help to improve the taste of jujube wine,and the fermentation method of jujube wine by adding nutrients was simple and feasible. | Guangpeng LIU Fatao HE Yongbo DOU Fengtao ZHU Ling GAO Le CHU Yan ZHAO | 2019 | Asian Agricultural Research2019，11，5： | 2 |
| 14 | JUPITER-02 trial: advancing survival for recurrent metastatic nasopharyngeal carcinoma and next steps显示文摘Nasopharyngeal carcinoma(NPC)is a disease with unique epidemiology.It is endemic in Southern China,Southeast Asia,and North Africa,and typically affects males more than females in the 30-60 years age group[1].Globally,133,354 NPC cases were diagnosed in 2020 with 80,008;deaths in the same year[2].While the survival rates of early-stage NPC after radiotherapy(RT)are high,dis-ease recurrences are common in locoregionally-advanced NPC,with the predominant pattern of failure being dis-tant metastasis[3].In this clinical scenario,palliative chemotherapy is the primary treatment modality。 | Laura Ling Ying Tan Quynh-Thu Le Nancy Ying Ying Lee Melvin Lee Kiang Chua | 2022 | Cancer Communications2022，42，1： | 2 |
| 15 | A novel spoof surface plasmon polariton structure to reach ultra-strong field confinements显示文摘Ultrathin corrugated metallic structures have been proved to support spoof surface plasmon polariton (SPP) modes on two-dimension (2D) planar microwave circuits.However,to provide stronger field confinement,larger width of strip is required to load deeper grooves,which is cumbersome in modern large-scale integrated circuits and chips.In this work,a new spoof SPP transmission line (TL) with zigzag grooves is proposed.This new structure can achieve stronger field confinement compared to conventional one with the same strip width.In other words,the proposed spoof SPP TL behaves equivalently to a conventional one with much larger size.Dispersion analysis theoretically indicates the negative correlation between the ability of field confinement and cutoff frequencies of spoof SPP TLs.Numerical simulations indicate that the cutoff frequency of the proposed TL is lower than the conventional one and can be easily modified with the fixed size.Furthermore,two samples of the new and conventional spoof SPP TLs are fabricated for experimental demonstration.Measured S-parameters and field distributions verify the ultra-strong ability of field confinement of the proposed spoof SPP TL.Hence,this novel spoof SPP structure with ultra-strong field confinement may find wide applications in microwave and terahertz engineering. | Pei Hang He Hao Chi Zhang Xinxin Gao Ling Yun Niu Wen Xuan Tang Jiayuan Lu Le Peng Zhang Tie Jun Cui | 2019 | Opto-Electronic Advances2019，2，6： | 2 |
| 16 | Mineralogy of Chang’e-4 landing site:preliminary results of visible and near-infrared imaging spectrometer显示文摘The exploration of mafic anomaly in South Pole-Aitken(SPA,the largest confirmed)basin on the Moon provides important insights into lunar interior.The landing of Chang’e-4(CE-4)and deployment of Yutu-2 rover on the discontinuous ejecta from Finsen crater enabled in-situ measurements of the unusual mineralogy in the central portion of SPA basin with visible and near-infrared imaging spectrometer(VNIS).Here we present detailed processing procedures based on the level 2B data of CE-4 VNIS and preliminary mineralogical results at the exploration area of Yutu-2 rover.A systematic processing pipeline is developed to derive credible reflectance spectra,based on which several spectral and mineral indices are calculated to constrain the mafic mineralogy.The mafic components in the soils and boulder around CE-4 landing site are concluded as clinopyroxene-bearing with intermediate composition and probably dominated by pigeonite although the possibility of mixing orthopyroxen(OPX)and calcic clinopyroxene(CPX)also exists.These mineralogical results are more consistent with a petrogenesis that the CE-4 regolith and rock fragment are derived from rapid-cooling magmatic systems and we interpret that the materials at the CE-4 landing site ejected from Finsen crater are probably recrystallized from impact melt settings. | Jian CHEN Zongcheng LING Le QIAO Zhiping HE Rui XU Lingzhi SUN Jiang ZHANG Bo LI Xiaohui FU Changqing LIU Xiaobin QI | 2020 | Science China(Information Sciences)2020，63，4： | 2 |
| 17 | Combination of a biopharmaceutic classification system and physiologically based pharmacokinetic models to predict absorption properties of baicalein in vitro and in vivo显示文摘Objective: To determine the in vitro and in vivo absorption properties of active ingredients of the Chinese medicine, baicalein, to enrich mechanistic understanding of oral drug absorption.Methods: The Biopharmaceutic Classification System(BCS) category was determined using equilibrium solubility, intrinsic dissolution rate, and intestinal permeability to evaluate intestinal absorption mechanisms of baicalein in rats in vitro. Physiologically based pharmacokinetic(PBPK) model commercial software GastroPlus~(TM) was used to predict oral absorption of baicalein in vivo.Results: Based on equilibrium solubility, intrinsic dissolution rate, and permeability values of main absorptive segments in the duodenum, jejunum, and ileum, baicalein was classified as a drug with low solubility and high permeability. Intestinal perfusion with venous sampling(IPVS) revealed that baicalein was extensively metabolized in the body, which corresponded to the low bioavailability predicted by the PBPK model. Further, the PBPK model predicted the key indicators of BCS, leading to reclassification as BCS-II. Predicted values of peak plasma concentration of the drug(C_(max)) and area under the curve(AUC)fell within two times of the error of the measured results, highlighting the superior prediction of absorption of baicalein in rats, beagles, and humans. The PBPK model supported in vitro and in vivo evidence and provided excellent prediction for this BCS class II drug.Conclusion: BCS and PBPK are complementary methods that enable comprehensive research of BCS parameters, intestinal absorption rate, metabolism, prediction of human absorption fraction and bioavailability, simulation of PK, and drug absorption in various intestinal segments across species. This combined approach may facilitate a more comprehensive and accurate analysis of the absorption characteristics of active ingredients of Chinese medicine from in vitro and in vivo perspectives. | Yang Liu Jing Sun Linying Zhong Yu Li A Na Er Tong Li Le Yang Ling Dong | 2021 | Journal of Traditional Chinese Medical Sciences2021，8，3： | 2 |
| 18 | Developing hierarchical CdS/NiO hollow heterogeneous architectures for boosting photocatalytic hydrogen generation显示文摘The hierarchical binary CdS/NiO hollow heterogeneous architectures(HHAs)with p–n heterojunction are constructed by a facile microwave-assisted wet chemical process for high-efficient photocatalytic hydrogen evolution reaction(HER)from water.The as-designed CdS/NiO HHAs are composed of hexagonal n-type CdS nanoparticles with a size in the range of 20–40 nm attaching to cubic p-type NiO hollow microspheres(HMSs)which are aggregates of porous nanoplates with a thickness of about 20 nm.The photocatalytic water splitting over CdS/NiO HHAs is significantly increased under simulated solar irradiation,among which the most active sample of CdS/NiO-3(the mass ratio of CdS to NiO is 1:3)exhibits the fastest photocatalytic HER rate of 1.77 mmol∙g^(−1)∙h^(−1),being 16.2 times than that of pure CdS.The boosted photocatalytic HER could be attributed to the synergistic effect on the proportional p–n heterojunction with special hierarchical hollow and porous morphology,an enhancement of visible light absorption,and an improvement of photoinduced charge separation as well as the photo-stability given by the composite heterojunction.This work shows a viable strategy to design the heterojunction with special morphology for the efficient hydrogen generation by water splitting utilizing solar energy. | Chonghai Deng Fan Ye Tao Wang Xiaohui Ling Lulu Peng Hong Yu Kangzhe Ding Hanmei Hu Qiang Dong Huirong Le Yongsheng Han | 2022 | Nano Research2022，15，3： | 2 |
| 19 | Antifreezing and Stretchable Organohydrogels as Soft Actuators显示文摘Inspired by the freezing tolerance performances found in living creatures, an effect approach is presented to develop novelantifreezing polymeric organohydrogel actuators. Through construction of a bilayer hydrogel including a nonresponsivepolyacrylamide (PAAm) layer and a pH-responsive polyacrylic acid (PAA) layer in the presence of a mixed solvent of water andglycerol, organohydrogel actuators that could produce various shape deformations at subzero temperatures have been achieved,and the actuating speed could be tuned by adjusting the temperature and the ratio between glycerol and water. Moreover, aseries of application demonstrations including a weightlifting robot, artificial valve, and robotic arm have been displayed. Inaddition, by introducing the ionic compound KI into the glycerol-based organogel, flexible conductors that could perform stablesensing performance over a wide range of temperatures from -30℃ to 60℃ have been developed. | Yukun Jian Baoyi Wu Xiaoxia Le Yun Liang Yuchong Zhang Dachuan Zhang Ling Zhang Wei Lu Jiawei Zhang Tao Chen | 2019 | Research2019，，1： | 2 |
| 20 | E-GrabCut: an economic method of iterative video object extraction显示文摘在录像的有效、交互前景 / 背景分割具有在录像编辑的大实际重要性。这份报纸建议当高度要求了在,一个交互、无指导的录像目标分割算法说出专注于分割质量和时间效率完成两个的 E-GrabCut 相关走。在建议算法有三个特征。第一,我们为每个框架开发了优化过程的一个强大的、非反复的版本。第二,在第一个框架的更多的用户相互作用被用来改进 Gaussian 混合模型(GMM ) 。第三,为下列框架分割的一个柔韧的算法被再使用以前的 GMM 开发了。广泛的实验证明我们的方法以时间效率和分割质量的集成超过最先进的录像分割算法。 | Le DONG Ning FENG Mengdie MAO Ling HE Jingjing WANG | 2017 | Frontiers of Computer Science2017，11，4： | 1 |
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