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| 1 | Heavy metal concentrations of agricultural soils and vegetables from Dongguan, Guangdong显示文摘118 农业土壤和 43 件蔬菜样品的一个总数从 Dongguan 城市被收集,广东,中国。空间分发,来源,累积特征和在农业土壤和蔬菜的重金属的潜在的风险被三条不同途径在细节描绘,包括在土壤和蔬菜的八个金属元素的全部的内容,在在学习的土壤的重金属的 GIS 地图和 multivariate 分析。结果证明在农业土壤有象 Cu , Zn , Ni , Pb , Cd 和 Hg 那样的重金属的更高的累积,并且 Pb 的内容( 65.38 mg kg ? 2 )并且 Hg ( 0.24 mg kg ? 2 )分别地是在广东省的土壤的相应重金属的背景内容的 1.82 和 2.82 次。有在附近的 3.4% Cu, 5.9% Ni, 1.7% Cd 和 28% Hg 在所有从有的所有调查地点收集了土壤样品溢出为为土壤标准的中国环境质量的重金属的内容(GB15618-1995,等级 II ) 。在土壤的多金属的污染特征被 Hg 主要反映。到在土壤的八个金属元素有不同来源, Cu, Zn, Ni, Cr 并且这是主要源于父母材料,并且 Pb, Hg 和 Cd 被人为的活动影响。空间分发表演 Cu, Zn, Ni, Cr, Pb 并且农业土壤的 Hg 内容在西方高并且在东方,和 Cd 内容低在西北高,东南并且在在 Dongguan 的西南低。Ni 的蔬菜样品的比率, Pb 并且作为比最大值高的集中,在食物(GB2762-2005 ) 的沾染物的层次分别地是 4.7% , 16.3% 和 48.8% 。在蔬菜的重金属的简历集中因素(BCF ) 的顺序是 Cd > Zn > Cu > 作为 > Ni > Hg > Cr > Pb。在 Dongguan 城市里从农业土壤和蔬菜为食物安全和人健康集中于重金属的潜在的风险是必要的,广东省。 | CAI Limei HUANG Lanchun ZHOU Yongzhang XU Zhencheng PENG Xiaochun YAO Ling'ai ZHOU Yang PENG Ping'an | 2010 | Journal of Geographical Sciences2010，20，1： | 23 |
| 2 | Report on Childhood Obesity in China (9): Sugar-sweetened Beverages Consumption and Obesity显示文摘Objective To explore the associations between sugar-sweetened beverage (SSB) consumption and obesity as well as obesity-related cardiometabolic disorders among children in China. Methods A total of 6974 (boys 3558, girls 3412) children aged 6-13 years participated in the study. Each participant's height, weight, waist circumference, fasting glucose, triglycerides, total cholesterol, high- density lipoprotein cholesterol, and low-density lipoprotein cholesterol were measured. The type of beverage consumption was determined using a self-administered questionnaire. Results SSBs were consumed regularly by 46.1% of the children. The prevalence [adjusted odds ratio (95% confidence internal (CI)] of obesity was 7.6% [as the reference group (ref.)], 10.1% [1.36(1.07, 1.74)], and 11.6% [1.46(1.21, 1.75)], among children who regularly drank milk, other beverages and SSBs, respectively. Regularly drinking SSBs elevated the likelihood of abdominal obesity [adjusted odds ratio (95% CI): 1.36 (1.17, 1.59)]. The prevalence [adjusted odds ratio (95% CI)] of obesity among children who regularly drank sports/caloric beverages, carbonated beverages, sweet tea, and plant protein beverages was 16.8% [2.00(1.31, 3.07)], 12.7% [1.52(1.23, 1.88)], 11.5% [1.52(1.18, 1.95)], and 10.4% [1.41(1.03, 1.94)], respectively, which was higher than that of regular milk drinkers [7.6 % (ref.)]. The prevalence [adjusted odds ratio (95% CI)] of abdominal obesity among children who regularly drank sweet tea, fruit/vegetable juices, and carbonated beverages was 17.7% [1.55(1.26, 1.90)], 16.2% [1.36(1.09, 1.70)], and 15.3% [1.24(1.03, 1.50)], respectively, which was much higher than that of regular milk drinkers [12.8% (ref.)]. Conclusions Regular SSB consumption was positively related to obesity and abdominal obesity. This relationship should be investigated further using a longitudinal study design. | SHANG Xian Wen LIU Ai Ling ZHANG Qian HU Xiao Qi DU Song Ming MA Jun XU Gui Fa LI Ying GUO Hong Wei DU Lin LI Ting Yu MA Guan Sheng | 2012 | Biomedical and Environmental Sciences2012，25，2： | 23 |
| 3 | Animal models for the study of hepatitis B virus infection显示文摘Even with an effective vaccine, an estimated 240 million people are chronically infected with hepatitis B virus(HBV) worldwide. Current antiviral therapies,including interferon and nucleot(s)ide analogues,rarely cure chronic hepatitis B. Animal models are very crucial for understanding the pathogenesis of chronic hepatitis B and developing new therapeutic drugs or strategies. HBV can only infect humans and chimpanzees, with the use of chimpanzees in HBV research strongly restricted. Thus, most advances in HBV research have been gained using mouse models with HBV replication or infection or models with HBV-related hepadnaviral infection. This review summarizes the animal models currently available for the study of HBV infection. | wei-na guo bin zhu ling ai dong-liang yang bao-ju wang | 2018 | Zoological Research2018，39，1： | 14 |
| 4 | Distribution and seasonal variation of estrogenic endocrine disrupting compounds,N-nitrosodimethylamine, and N-nitrosodimethylamine formation potential in the Huangpu River, China显示文摘Detection of estrogenic endocrine disrupting compounds(EDCs) and N-nitrosodimethylamine(NDMA) in drinking water has led to rising concerns. There are, however, a paucity of studies on the distribution and seasonal variation of NDMA and NDMA formation potential(NDMA-FP) in natural waters, especially in China. For EDCs, limited studies have investigated the distribution and seasonal variation of estrone(E1), 17β-estradiol(E2), estriol(E3), 17α-ethinylestradiol(EE2), technical-nonylphenols(t-NP), and bisphenol A(BPA) in Shanghai. In this study, water samples were collected from 11 sampling sites along the Huangpu River in 2012. The distribution and seasonal variation of EDCs, NDMA, and NDMA-FP were investigated. The results showed that all of the 11 sampling sites were contaminated by the target compounds. Compared with E2 and EE2, higher E1 and E3 concentrations were usually detected in the Huangpu River. The values of 17β-estradiol equivalents(EEQ) suggest a high possibility of endocrine effects on exposed organisms in the Huangpu River. NDMA-FP and t-NP were the dominant contaminants among the eight target compounds. The detection rates of the target compounds and their concentrations were both higher in dry seasons than in wet seasons. Higher concentrations of target compounds were observed in urban sampling sites near drainage outlets, and also in suburban sampling sites where intensive livestock farming and farmlands were located. | Ai Zhang Yongmei Li Ling Chen | 2014 | Journal of Environmental Sciences2014，26，5： | 12 |
| 5 | Methodology and Application for Health Risk Classification of Chemicals in Foods Based on Risk Matrix显示文摘The method has been developed to accurately identify the magnitude of health risks and provide scientific evidence for implementation of risk management in food safety.It combines two parameters including consequence and likelihood of adverse effects based on risk matrix.Score definitions and classification for the consequence and the likelihood of adverse effects are proposed.The risk score identifies the intersection of consequence and likelihood in risk matrix represents its health risk level with different colors:‘low',‘medium',‘high'.Its use in an actual case is shown. | ZHOU Ping Ping LIU Zhao Ping ZHANG Lei LIU Ai Dong SONG Yan YONG Ling LI Ning | 2014 | Biomedical and Environmental Sciences2014，27，11： | 11 |
| 6 | Identification of AtENT3 as the main transporter for uridine uptake in Arabidopsis roots显示文摘当在酵母细胞生产了,差别在 Arabidopsis 器官被表示时,以前的研究证明了 Arabidopsis equilibrative nucleoside 运输 ers (AtENTs ) 拥有运输活动。此处,我们在 nucleoside 运输活动和 AtENT 成员的 transcriptional 模式报导进一步的分析。AtENTs 3 的 recombinant 蛋白质, 6,和 7,然而并非那些 AtENTs 1, 2, 4,和 8,被发现与高亲密关系搬运 thymidine。与以前的建议相反,那 AtENT1 不能搬运 uridine,这个工作证明 recombinant AtENT1 是 uridine 的 pH 依赖、高亲密关系的 transporter。当在 MS 盘子上成长时, AtENT3 猛烈植物比野类型的植物和 AtENT1 或 AtENT6 的猛烈植物对细胞毒素的 uridine 类似物 5-fluorouridine 更容忍。与这观察一致, AtENT3 猛烈的线展出了一个显著地减少的能力收起[(3 ) H ] 经由根的 uridine 什么时候与有变异的 AtENT1 或 AtENT6 的野类型的植物和植物相比。这显示那 AtENT3,然而并非 AtENTs 1 并且 6,是为在 Arabidopsis 根的 uridine 举起的主要 transporter。AtENTs 1 的抄写, 3, 4, 6, 7,和 8 在叶开发和老朽期间以一种复杂方式被调整。相反,六个 AtENT 成员并列地在种子萌芽期间被劝诱。这个工作为未来研究在 recombinant AtENT 蛋白质和新线索的运输性质上提供新信息在里面 vivo 运输活动和在 Arabidopsis 工厂的不同 ENT 蛋白质的生理的功能。 | Kun Ling Chen Min Xin Xu Guang Yong Li Hui Liang Zong Liang Xia Xin Liu Ji Shu Zhang Ai Min Zhang Dao Wen Wang | 2006 | Cell Research2006，16，4： | 7 |
| 7 | Night Sleep Duration and Risk of Cognitive Impairment in a Chinese Population: A Cross-sectional Study显示文摘Objective Although sleep is one of the most important health-related behavioral factors,the association between night sleep duration and cognitive impairment has not been fully understood.A cross-sectional study was conducted with a random sample of 2,514 participants(≥40 years of age;46.6% women) in China to examine the association between night sleep duration and cognitive impairment.Methods Night sleep duration was categorized as ≤ 5,6,7,8,or ≥9 h per night.Cognitive function was measured using the Mini-Mental State Examination.A multivariate regression analysis was used to analyze the association of night sleep duration with cognitive impairment.A total of 122 participants were diagnosed with cognitive impairment.Results A U-shaped association between night sleep duration and cognitive impairment was found.The odds ratios(95% confidence intervals) of cognitive impairment(with 7 h of daily sleep being considered as the reference) for individuals reporting ≤ 5,6,8,and ≥9 h were 2.14(1.20-3.83),1.13(0.67-1.89),1.51(0.82-2.79),and 5.37(1.62-17.80),respectively(P≤0.01).Conclusion Short or long night sleep duration was an important sleep-related factor independently associated with cognitive impairment and may be a useful marker for increased risk of cognitive impairment. | SONG Qiao Feng LIU Xiao Xue HU Wan Ning HAN Xiao Chen ZHOU Wen Hua LU Ai Dong WANG Xi Zhu WU Shou Ling | 2017 | Biomedical and Environmental Sciences2017，30，10： | 5 |
| 8 | Synthesis and anti-tumor activity evaluation of novel podophyllotoxin derivatives显示文摘In order to investigate the effects on the cytotoxicity of indole-3-oxalylamino podophyllotoxin analogs, seven novel podophyllotoxin derivatives were synthesized.The compounds were tested against Hela, K562 or K562/A02 cancer cells in vitro,four of which showed significant cytotoxicity.Among them 9a,9b and 9c were superior to the positive control VP-16. | Ting Ai Shao-Yu Shi Li-Ting Chen Ling Li Bo Cao Ying Gao Hong Chen Jing Zhou | 2013 | Chinese Chemical Letters2013，24，1： | 5 |
| 9 | Estimating the Health and Economic Outcomes of the Prevention of Mother-to-child Transmission of HIV Using a Decision Tree Model显示文摘In 2016, there were 17.8 million (15.4-20.3 million) women living with HIV/AIDS across the world and the prevalence of reproductive desire among this group was 26%-49%[1]. If pregnant women living with HIV/AIDS are left untreated, the rates of HIV transmission from mother-to-child would range from 14% to 48%, depending on the presence and duration of breastfeeding[2]. | QU Shui Ling WANG Ai Ling PAN Xiao Ping WANG Qian DOU Li Xia ZHANG Tong | 2019 | Biomedical and Environmental Sciences2019，32，1： | 4 |
| 10 | Effect of large load on the wear and corrosion behavior of high-strength EH47 hull steel in 3.5wt%NaCl solution with sand显示文摘To simulate the wear and corrosion behavior of high-strength EH47 hull steel in a complicated marine environment in which seawater,sea ice,and sea sand coexist,accelerated wear and corrosion tests were performed in a laboratory setting using a tribometer.The effect of large loads on the behavior of abrasion and corrosion in a 3.5wt%NaCl solution with ice and sand to simulate a marine environment were investigated.The experimental results showed that the coefficient of friction(COF)decreases with increasing working load;meanwhile,the loading force and sand on the disk strongly influence the COF.The mechanisms of friction and the coupling effect of abrasion and corrosion in the 3.5wt%NaCl solution with sand were the wear and corrosion mechanisms;furthermore,the wear mechanism exerted the predominant effect. | Hong-mei Zhang Yan Li Ling Yan Fang-fang Ai Yang-yang Zhu Zheng-yi Jiang | 2020 | International Journal of Minerals,Metallurgy and Materials2020，27，11： | 4 |
| 11 | Optimal Waist Circumference Cut-off values for Identifying Metabolic Risk Factors in Middle-aged and Elderly Subjects in Shandong Province of China显示文摘Objective To study the optimal waist circumference(WC) cut-off values for identifying metabolic risk factors in middle-aged and elderly subjects in Shandong Province of China. Methods A total of 2 873 men and 5 559 women were included in this cross-sectional study. Metabolic syndrome(MetS) was diagnosed according to the definition of Chinese Diabetes Society in 2004. The relation between WC and MetS was analyzed by multivariate logistic regression analysis. The optimal WC cut-off values were identified using the area under the ROC curve and the different diagnostic criteria for central obesity were compared. Results The WC was the risk factor for MetS independent of BMI, blood glucose, blood lipid, and blood pressure. The optimal WC cut-off value was 83.8 cm and 91.1 cm for identifying MetS in women and men, respectively. Compared with 80 cm and 85 cm for women and men, 85 cm and 90 cm had a higher Youden index for identifying all metabolic risk factors and MetS in women and men. Conclusion The appropriate WC cut-off value is 85 cm and 90 cm for identifying central obesity and MetS in women and men in Shandong Province of China. | HOU Xin Guo WANG Chuan MA Ze Qiang YANG Wei Fang WANG Ji Xiang LI Cheng Qiao WANG Yu Lian LIU Shu Min Hu Xiu Ping ZHANG Xiu Ping JIANG Mei WANG Wei Qing NING Guang ZHENG Hui Zhen MA Ai Xia SUN Yu SONG Jun LIN Peng LIANG Kai LIU Fu Qiang LI Wen Juan XIAO Juan GONG Lei WANG Mei Jian LIU Ji Dong YAN Fei YANG Jun Peng WANG Ling Shu TIAN Meng ZHAO Ru Xing JIANG Ling CHEN Li | 2014 | Biomedical and Environmental Sciences2014，27，5： | 3 |
| 12 | 90d Exposure to Nonylphenol has Adverse Effects on the Spermatogenesis and Sperm Maturation of Adult Male Rats显示文摘This study was conducted to elucidate the reproductive effect of NP on testis,epididymis and epididymal sperm in vivo.Adult male SpragueDawley rats were gavaged with NP at 0,40,100,or 250 mg/kg body weight(bw) on alternate days for 90 d.The results showed that oral administration of NP may damage the structure and function of testis,induce apoptosis and oxidative stress in epididymis or even have cytotoxic effects on epididymal sperm. | LU Wei Chen WANG Ai Qing CHEN Xiao Ling YANG Guo LIN Yao CHEN Yi Ou HONG Cheng Jiao TIAN Hai Lin | 2014 | Biomedical and Environmental Sciences2014，27，11： | 3 |
| 13 | Crustal thickness and composition in the South China Block:Constraints from earthquake receiver function显示文摘Crustal thickness and composition are closely related to geology and tectonic evolution of the region.Studying the differences in the crustal thickness and composition of the South China Block(SCB)is important to gain a comprehensive understanding of multi-phase amalgamation,breakup,reworking,and regional geodynamic processes.In this study,teleseismic data from 135 high-density portable broadband stations from Sino Probe were processed using Common Conversion Point(CCP)stacking and H-κstacking methods.The Moho depth and P-wave and S-wave velocity ratio(V_(p)/V_(s))were studied.Our results revealed several insights about the tectonic processes in the SCB.First,the crustal structure and V_(p)/V_(s)ratios of the Cathaysia Block,Jiangnan Orogenic Belt,and Yangtze Block were significantly different.The average depth of the Moho in the Cathaysia Block was approximately 31 km,and the V_(p)/V_(s)ratios increased from the inland area(1.66)to the coastal area(1.78),indicating the oceanward increase of mafic proportion in the lower crust,which is related to the influence of the Paleo-Pacific Plate westward subduction.Second,the crustal thickness of Jiangnan Orogenic Belt deepens from east ca.31 to the west ca.42 km and the V_(p)/V_(s)ratios varied from 1.75 to 1.64,illustrating a relatively felsic crust,which could have been related to the Mesozoic upper crustal thickening under compression followed by the lower crust removal under the extensional background.Third,the average crustal thickness of the Yangtze Block was 42 km,and the V_(p)/V_(s)ratios ranged from 1.64 to 1.84,presenting a positive correlation between the Moho depth and the V_(p)/V_(s)ratio,which is explained by the relatively thick mafic lower crust.Based on the variations in the crustal structure and V_(p)/V_(s)ratios of the profile,we inferred that the central part of the Jiangnan Orogenic Belt was bounded by the Jiangshan-Shaoxing-Hengyang in the east and the Jiujiang-Shitai-Jishou in the west.The small-scale Moho depth undulations at the intersection of the Cathaysia Block and the Jiangnan Orogenic Belt could be related to the Mesozoic compression-extension geodynamic transformation. | Changxin CHEN Qingtian LÜ Ling CHEN Danian SHI Jiayong YAN Yinshuang AI | 2022 | Science China Earth Sciences2022，65，4： | 3 |
| 14 | Preparation and Characterization of Three-dimensionally Ordered Crystalline Macroporous CeO_2显示文摘A stable 3DOM CeO2 with well-defined inverse opal microstructure and crystalline walls structure has been successfully synthesized by application of three-dimensional order PMMA beads as templates. Structural feature of products was characterized by using SEM, DTA-TG, XRD. | Xi Yan ZHANG Tong Wen WANG Wen Qing JIANG Di WU Ling LIU Ai Hong DUAN | 2005 | Chinese Chemical Letters2005，16，8： | 3 |
| 15 | Evaluating the Quality of Case-control Studies involving the Association between Tobacco Exposure and Diseases in a Chinese Population based on the Newcastle-Ottawa Scale and Post-hoc Power显示文摘According to the 2017 Global Burden of Disease Study,smoking is among the four leading risk factors contributing to deaths and disability-adjusted life years(DALYs)in China.In the past 20 years,there has been a substantial increase in the number of studies focusing on the association between tobacco exposure and disease. | SHI Yu Lin ZHAO Jian AI Fei Ling WANG Yu Tong HU Kui Ru WANG Xue Wei YANG Wen Yi WANG Jing Xin AI Li Mei WAN Xia | 2022 | Biomedical and Environmental Sciences2022，35，9： | 2 |
| 16 | Anti-hypercholesterolemic effect of kenaf(Hibiscus cannabinus L.)seed on high-fat diet Sprague dawley rats显示文摘Objective:To determine? the anlihypercholesterolemic effects of kenaf seed samples and compare with the commercial hypocholesterolemic drug on serum lipids profiles and malondialdehyde(MDA) level in the rat.Methods:Kenaf seed oil(KSO),microencapsulated kenaf seed oil(MKSO),kenaf seed extract(KSE) and defatted kenaf seed meal(DKSM) were prepared and phytocHemicals screening on these samples were done prior in viro study.Phenolic compounds in KSF.were quantified using high performance liquid chromatography.There were 40(divided in eight diet groups of 5) male Sprague dawley rats adapted lo normal standard diet or hypercholesterolemic diet(HD) with or without the treatment of these kenaf samples for 32 days.Results:All the kenaf samples exhibited to contain most of the major phytocliemicals.KSE possessed gallic acid,tannic acid,catechin.benzaldehyde.benzoic acid,syringic acid,sinapic acid,ferulic acid,naringin acid,and protocatechuic acid.The significant higher(P<0.05) serum total cholesterol,low density lipoprotein cholesterol and MDA levels in HD group without treatment than the normal control group suggested the hypercholesterolemia was induced by the Incorporation of cholesterol into diet.KSE exhibited higher cholesterol-lowering properties due to the significant lower(P<0.05)in serum triglycerides,total cholesterol and MDA levels.KSF showed the highest efficiency of cholesterol-lowering activity,followed by KSO.MKSO and DKSM.Conclusions:DKSM.MKSO.KSO and KSE appeared lo have comparable anti-hypercholesterolemic effect with the commercial hypocholesterolemic drug.Hence,kenaf seed could be used as an alternative natural source lo replace the synthetic hypocholosterolemic drugs. | Ng Shy Kai Tee Ai Nee Elaine Lai Chia Ling Tan Chin Ping Long Kamariah Nyam Kar Lin | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，1： | 2 |
| 17 | Proton irradiation effects on HVPE GaN显示文摘GaNs grown by hydride vapor phase epitaxy(HVPE) were irradiated by protons with different fluences.The changes of surface topography of as-grown and irradiated samples were characterized by atomic force microscopy(AFM).The crystal quality and optical properties of GaN films were examined by the variations of the micro-Raman and photoluminescence(PL) spectra with proton fluence.It was observed that the surface became a little more rough after irradiation.The Raman spectra indicated that the strain of materials and carrier concentration were not affected by the proton injection.The full-width at half-maximum(FWHM) of E 2 high phonon mode narrowed,which was consistent with the FWHM of PL near-band-edge emission(BE).The spectra of yellow luminescence and blue luminescence normalized to the intensity of BE demonstrated a little increase of Ga vacancy and a large decrease of O N,which may be the main reason for the change of optical properties. | LU Ling HAO Yue ZHENG XueFeng ZHANG JinCheng XU ShengRui LIN ZhiYu AI Shan MENG FanNa | 2012 | Science China(Technological Sciences)2012，55，9： | 2 |
| 18 | Environmental Monitoring of A Laboratory for New Coronavirus Nucleic Acid Testing显示文摘The coronavirus disease 2019(COVID-19) is an infection of the respiratory tract which first broke out in Wuhan, China, in December 2019. The etiologic agent of this disease was identified as a betacoronavirus related to severe acute respiratory syndrome coronavirus(SARS-CoV). Thus, the International Committee on Virus Classification named the new coronavirus severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)[1]. | NING Pei Yong YU Ai Ping WANG Yuan GUO Li Ru SHAN Dan KONG Mei YU Ling Qi LYU Li Kun ZOU Ming SU Xu FEI Chun Nan ZHOU Yu Hui WANG Bai Qi | 2020 | Biomedical and Environmental Sciences2020，33，10： | 2 |
| 19 | Mitochondrial fusion protein 2 regulates endoplasmic reticulum stress in preeclampsia显示文摘Preeclampsia(PE)refers to a group of dysfunction syndromes associated with elevated blood pressure and proteinuria in women with previously normal blood pressure after 20 weeks of pregnancy,and it may be accompanied by symptoms including headache。 | Dandan SUN Hui ZHU Ling AI Hanbing WU Yanting WU Jihua JIN | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，2： | 2 |
| 20 | Lactate anions participate in T cell cytokine production and function显示文摘After antigen stimulation, T cells preferentially increase aerobic glycolysis to meet the bioenergetic and biosynthetic demands of T cell activation, proliferation, and effector functions. Lactate, a by-product of glycolysis, has been reported to function as an important energy source and signaling molecule. Here, we found that lactate anions are involved in cytokine production in Tcells after TCR activation. During ex vivo T cell activation, the addition of excess sodium lactate(Na L) increased the production of cytokines(such as IFNγ/IL-2/TNFα) more than the addition of sodium chloride(NaCl). This enhanced cytokine production was dependent on TCR/CD3 activation but not CD28 activation. In vivo, Na L treatment inhibited tumour growth in subcutaneously transplanted tumour models in a T cell-dependent manner, which was consistent with increased T cell cytokine production in the Na L treatment group compared to the Na Cl treatment group. Furthermore, a mechanistic experiment showed that this enhanced cytokine production was regulated by GAPDH-mediated post-transcriptional regulation. Taken together, our findings indicate a new regulatory mechanism involved in glycolysis that promotes T cell function. | Jing Wen Shipeng Cheng Yaguang Zhang Ran Wang Jiefang Xu Zhiyang Ling Liyan Ma Xinghao Ai Bing Sun | 2021 | Science China(Life Sciences)2021，64，11： | 2 |
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