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| 1 | The Reference Genome of Tea Plant and Resequencing of 81 Diverse Accessions Provide Insights into Its Genome Evolution and Adaptation显示文摘Tea plant is an important economic crop,which is used to produce the world's oldest and most widely consumed tea beverages.Here,we present a high-quality reference genome assembly of the tea plant(Camellia sinensis var.sinensis)consisting of 15 pseudo-chromosomes.LTR retrotransposons(LTR-RTs)account for 70.38%of the genome,and we present evidence that LTR-RTS play critical roles in genome size expansion and the transcriptional diversification of tea plant genes through preferential insertion in promoter regions and introns.Genes,particularly those coding for terpene biosynthesis pro-teins,associated with tea aroma and stress resistance were significantly amplified through recent tandem duplications and exist as gene clusters in tea plant genome.Phylogenetic analysis of the sequences of 81 tea plant accessions with diverse origins revealed three well-differentiated tea plant populations,support-ing the proposition for the southwest origin of the Chinese cultivated tea plant and its later spread to western Asia through introduction.Domestication and modern breeding left significant signatures on hundreds of genes in the tea plant genome,particularly those associated with tea quality and stress resis-tance.The genomic sequences of the reported reference and resequenced tea plant accessions provide valuable resources for future functional genomics study and molecular breeding of improved cul-tivars of tea plants. | Enhua Xia Wei Tong Yan Hou Yanlin An Linbo Chen Qiong Wu Yunlong Liu Jie Yu Fangdong Li Ruopei Li Penghui Li Huijuan Zhao Ruoheng Ge Jin Huang Ali Inayat Mallano Yanrui Zhang Shengrui Liu Weiwei Deng Chuankui Song Zhaoliang Zhang Jian Zhao Shu Wei Zhengzhu Zhang Tao Xia Chaoling Wei Xiaochun Wan | 2020 | Molecular Plant2020，13，7： | 51 |
| 2 | Livestock-carrying capacity and overgrazing status of alpine grassland in the Three-River Headwaters region, China显示文摘在中国的三河的 Headwaters 区域是为中流和下游的区域提供环境保护和地区性的持续开发的一个生态的障碍,它也在中国在畜牧起一个重要作用。这研究基于 MODIS NPP 数据在三河的 Headwaters 区域估计了草地收益,并且计算了草地的合适的带家畜的能力。我们通过在实际、合适的带家畜的能力之间的数据比较分析了过度放牧的数字和它的空间分发特征。结果显示出下列:(1 ) 在三河的 Headwaters 区域的全部的草地产量(干草) 与 465.70 kg/hm2 的平均草地收益是在 2010 的 1096 万吨(空间分发接着从东方和东南介绍一个减少的趋势给西方和西北) ;( 2 )在三河的 Headwaters 区域的合适的带家畜的能力是1219万个绵羊单位(此后描述了为苏),并且平均袜子能力是 51.27 苏[合适的带能力在在东方县的 100 SU/km2 上面,在中央县的 60 SU/km2 (除了 Madoi 县),并且在西方的县的 30 SU/km2 ];并且(3 ) 全部的过度放牧数字是在在 2010 的三河的 Headwaters 区域的 652 万苏,与过度放牧的一般水准, 67.88% 的比率和过度放牧的一般水准 27.43 SU/km2 数。更高的过度放牧比率发生在 Tongde, Xinghai, Yushu,河南省和 Z ? 甠据牥慴湩祴漠 ? 桴 ? 慣楬牢瑡潩 ? 敲?瑬 ? 慷 ? 癥污慵整 ? 祢瀠牥潦浲湩 ? 档牡吗?? | ZHANG Jiping | 2014 | Journal of Geographical Sciences2014，24，2： | 25 |
| 3 | A SET OF SYMMETRIC QUADRATURE RULES ON TRIANGLES AND TETRAHEDRA显示文摘我们在场为在三角形和 tetrahedra 上计算对称的照规则的一个节目。一套规则被使用这个节目获得。照规则多达在三角形上并且直到为在有限元素计算的使用有用的 14 在 tetrahedra 上被获得了的顺序订 21。这里介绍的所有规则有积极重量,点躺在集成领域以内。[从作者抽象] | Linbo Zhang Tao Cui Hui Liu | 2009 | Journal of Computational Mathematics2009，27，1： | 5 |
| 4 | Fucoxanthin induces growth arrest and apoptosis in human bladder cancer T24 cells by up-regulation of p21 and down-regulation of mortalin显示文摘Fucoxanthin,自然类胡萝卜素,被报导了在人的结肠癌房间,人的前列腺癌症房间,人的白血病房间,和人的上皮的颈的癌症房间举办反癌症活动。这研究被承担把 fucoxanthin 的分子的机制与人的膀胱癌症 T24 房间线作比较。 MTT 分析结果证明 5 和 10 M fucoxanthin 在生长拘捕在 G 0/G1伴随的一个剂量依赖者和时间依赖者举止禁止了 T24 房间的增长房间周期的阶段,被 p21 的起来规定调停,cyclin依赖的 kinase ( CDK )禁止的蛋白质和 CDK-2 , CDK-4 , cyclin D1 ,和 cyclin E 的下面规定。另外, 20 和 40 M fucoxanthin 由 mortalinp53 建筑群的废除和原子变异类型的 p53 的复活导致了 T24 房间的 apoptosis,它也让肿瘤 suppressor 作为野类型的 p53 工作。所有这些结果证明 T24 房间上的 fucoxanthin 的反癌症活动被 p21 的起来规定经由在 mortalin ,它是的表示水平,一个压力管理者和热的一个成员震惊的减少在低剂量和 apoptosis 在 G 0/G1阶段与房间周期拘捕联系蛋白质 70 ,在高剂量由劈开的 caspase-3 的起来规定列在后面。 | Linbo Wang Yang Zeng Ye Liu Xuansheng Hu Shuhong Li Yuepeng Wang Ling Li Zhongfang Lei Zhenya Zhang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，10： | 5 |
| 5 | Preparation and Corrosion Resistance of Anodic Oxidation Coatings on 2198 and 5A90 Al-Li Alloys显示文摘2198 and 5A90 Al-Li alloys were anodized with a constant DC potential in 18%H_2SO_4solution(Solu.A) and the mixture solution of 18%H_2SO_4+5%C_2H_2O_4(Solu.B) at room temperature. 12 and 11 V was optimized as the applied oxidation potential for 2198 and 5A90 alloys, respectively. Cross-sectional morphology, surface morphology and elements distribution of anodic oxidation coatings were observed by scanning electron microscope equipped with energy dispersive X-ray analysis(SEM/EDX). Corrosion resistance was tested by potentiodynamic polarization plot in 3.5%NaCl solution. The results showed that the thicknesses of coatings obtained at the selected potential in Solu.A and Solu.B were about 50 μm/110 μm for 2198 alloy and 80 μm/110 μm for 5A90 alloy. In both solutions, anodic oxidation coatings of 2198 alloy were primarily composed of Al oxides; those of 5A90 alloy were mainly consisted of Al oxides and a small amount of Mg oxides. The results of potentiodynamic polarization showed that anodic oxidation coatings of 2198 and 5A90 Al-Li alloys had better corrosion resistances than that of untreated alloys. | 王赫男 LI Xinming HE Linbo CUI Baolei LIU Chunzhong | 2019 | Journal of Wuhan University of Technology(Materials Science)2019，34，1： | 3 |
| 6 | Regulation of mATG9 trafficking by Src- and ULK1mediated phosphorylation in basal and starvation-induced autophagy显示文摘Autophagy 要求多样的膜来源并且包含 mATG9 的膜 trafficking,在 ATG 家庭的唯一的膜蛋白质。然而,为 autophagy 开始的 mATG9 trafficking 的分子的规定仍然保持不清楚。这里,我们识别了在 mATG9 的 cytosolic N 终点以内排序信号的二保存经典适配器蛋白质,它调停从经由和 AP1/2 建筑群的相互作用的血浆膜和 trans-Golgi 网络(TGN ) 的 mATG9 的 trafficking。在 Tyr8 到的 Src phosphorylates mATG9 处于不着重的条件维持它的 endocytic 和组成的 trafficking。响应饥饿,在由 Src 的 Tyr8 并且在由 ULK1 的 Ser14 的 mATG9 的 phosphorylation 机能上地合作支持在 mATG9 和 AP1/2 建筑群之间的相互作用,为 autophagy 从血浆膜和 juxta 原子的区域导致 mATG9 的再分配到外部水池开始。我们的调查结果揭开 mATG9 trafficking 的新奇机制并且建议基础、导致压力的 autophagy 的协作。 | Changqian Zhou Kaili Ma Ruize Gao Chenglong Mu Linbo Chen Qiangqiang Liu Qian Luo Du Feng Yushan Zhu Quan Chen | 2017 | Cell Research2017，27，2： | 2 |
| 7 | Construction and identification of an RNA interference lentivirus vector targeting the Ras homology C gene of melanoma cells显示文摘 | Wang Qiying Wang Ximei Zhai Xiaomei Zhang Jianwen Chen Minjing Liu Linbo | 2014 | Chinese Medical Journal2014，，7： | 2 |
| 8 | Synthesis of ZSM-5 with the silica source from industrial hexafluorosilicic acid as transalkylation catalyst显示文摘A new effective process to improve the utilization of industrial fluorosilicic acid of phosphate fertilizer by-product has been investigated to comprehensive application of the silicon and fluorine source. Two-step ammoniation was applied to recover high-quality silica. The recovered silica can be used to hydrothermal synthesize ZSM-5 zeolite without impurity phase contamination, which was confirmed by XRD, TG, SEM, BET and EDS characteristic techniques. It was found that with the increase of SiO_2/Al_2O_3 ratio and the extension of reaction time, the crystal type transform from the orthorhombic to the monoclinic phase. The impurity fluorine content of the recovered SiO_2 from H_2SiF_6 has great influence on the hydrothermal process for ZSM-5 crystal structure formation.Moreover, the increase of fluorine ions content in the hydrothermal process can control the crystal morphology and size of synthesized ZSM-5. Catalytic properties of synthesized HZSM-5 with different SiO_2/Al_2O_3 ratio in transalkylation of toluene and 1,2,4-trimethylbenzene show good and stable catalytic performance. The ZSM-5 synthesized with recovered silica source exhibits similar catalyst life as the performance of small particle size HZSM-5, because the ZSM-5 synthesized with the silica source from industrial hexafluorosilicic acid prefers a thin disk crystal along the b axis direction, which shortens the diffusion distance of generated products. | Fang Jin Xianqiao Wang Tieliang Liu Linbo Xiao Ming Yuan Yangchun Fan | 2017 | Chinese Journal of Chemical Engineering2017，25，9： | 1 |
| 9 | Adsorption of cations onto the surfaces of silver nanoparticles显示文摘 | Yun Liu Chunyan Liu Linbo Chen | 2003 | Interface Science2003，，257： | 1 |
| 10 | Disruption Coordination of Closed-Loop Supply Chain Network (11) Analysis and Simulations显示文摘 | Lindu Zhao Ming Liu and Linbo Qu | 2009 | International Journal of Innovative Computing Information and Control2009，5，2： | 1 |
| 11 | Lin28 Mediates Paclitaxel Resistance by Modulating p21,Rb and Let-7a miRNA in Breast Cancer Cells显示文摘 | Kezhen Lv Liqun Liu Linbo Wang | 2012 | PLoS ONE2012，7，： | 1 |
| 12 | Application of Fetal Carti-lage Grafts in the Reshaping of the Nasal Tip显示文摘 | Wang Lu Liu Linbo Zhu Ying | | 0，，05： | 1 |
| 13 | Toxic effects of citrinin on the male reproductive system in mice显示文摘 | Han Qingqing Yu Linbo Guo Yunqian Liu Shuqiang | 2010 | Experimental and Toxicologic Pathology2010，，： | 1 |
| 14 | Highly active CoP-CO_(2)N confined in nanocarbon enabling efficient electrocatalytic immobilizing-conversion of polysulfide targeting high-rate lithium-sulfur batteries显示文摘Lithium-sulfur batteries suffer from poor cycling stability because of the intrinsic shuttling effect of intermediate polysulfides and sluggish reaction kinetics,especially at high rates and high sulfur loading.Herein,we report the construction of a CoP-CO_(2)N@N-doped carbon polyhedron uniformly anchored on three-dimensional carbon nanotubes/graphene(CoP-CO_(2)N@NC/CG)scaffold as a sulfur reservoir to achieve the trapping-diffusion-conversion of polysulfides.Highly active CoP-CO_(2)N shows marvelous catalytic effects by effectively accelerating the reduction of sulfur and the oxidation of Li_(2)S during the discharging and charging process,respectively,while the conductive NC/CG network with massive mesoporous channels ensures fast and continuous long-distance electron/ion transportation.DFT calculations demonstrate that the CoP-CO_(2)N with excellent intrinsic conductivity serves as job-synergistic immobilizing-conversion sites for polysulfides through the formation of P…Li/N…Li and Co…S bonds.As a result,the S@CoP-CO_(2)N@NC/CG cathode(sulfur content 1.7 mg cm^(-2))exhibits a high capacity of988 mAh g^(-1)at 2 C after 500 cycles,which is superior to most of the electrochemical performance reported.Even under high sulfur content(4.3 mg cm^(-2)),it also shows excellent cyclability with high capacity at 1 C. | Xiaojun Zhao Tianqi Gao Wenhao Ren Chuan Zhao Zhi-Hong Liu Linbo Li | 2022 | Journal of Energy Chemistry2022，，12： | 1 |
| 15 | Cluster Randomization Trial of Sequence Mass Screening for Colorectal Cancer显示文摘 | Shu Zheng M.D. Kun Chen M.D. Xiyong Liu M.D. Xinyuan Ma M.D. Hai Yu Ph.D. Kang Chen Kaiyan Yao Lun Zhou M.D. Linbo Wang M.D. Peiling Qiu M.D. Yongchuan Deng M.D. Suzhan Zhang M.D | 2003 | Diseases of the Colon & Rectum2003，，1： | 1 |
| 16 | Carbon storage of a subtropical forest ecosystem: a case study of the Jinggang Mountain National Nature Reserve in south-eastern China显示文摘The carbon cycle of forest ecosystems plays a key role in regulating CO2 concentrations in the atmosphere. Research on carbon storage estimation of forest ecosystems has become a major research topic. However, carbon budgets of subtropical forest ecosystems have received little attention. Reports of soil carbon storage and topographic heterogeneity of carbon storage are limited. This study focused on the Jinggang Mountain National Nature Reserve as an example of a mid-subtropical forest and evaluated soil and vegetation carbon storage by field sampling combined with GIS, RS and GPS technology. We classified the forest into nine forest types using ALOS high-resolution remote sensing images. The evergreen broad-leaved forest has the largest area, occupying 26.5% of the total area, followed by coniferous and broad-leaved mixed forests and warm temperate coniferous forest, occupying 24.2 and 22.9%, respectively. The vegetation and soil carbon storage of the whole forest ecosystem were 1,692,344 and 5,514,707 t, with a carbon density of 7.4 and 24.2 kg/m^2, respectively, which suggests that the ecosystem has great carbon storage capacity. The topographic heterogeneity of the carbon storage was also analysed. The largest vegetation storage and soil storage is at 700–800 and 1000–1100 m, respectively. The vegetation carbon storage is highest in the southeast, south and southwest. | Jiping Zhang Linbo Zhang Haiguang Hao Chunlan Liu Hui Wang | 2019 | Journal of Forestry Research2019，30，3： | 1 |
| 17 | Temporal dynamic changes of connexin 43 expression in C6 cells following lipopolysaccharide stimulation显示文摘Connexin 43,a gap junction protein,is expressed mainly in glia in the central nervous system.Neuroinflammation plays an important role in central nervous system injury.Changes to glial connexin 43 levels and neuroinflammation may trigger brain injury and neurodegenerative diseases.To illustrate the relationship between connexin 43 and neuroinflammation,this study investigated how connexin 43 expression levels change in lipopolysaccharide-stimulated rat C6 glioma cells.C6 cells were treated with 0.05,0.25,0.5,1,2.5 and 5 μg/mL lipopolysaccharide for 24 hours.The nitrite estimation-detected nitric oxide release level was elevated substantially after lipopolysaccharide stimulation.To test the transcriptional level changes of inducible nitric oxide synthase,tumor necrosis factor-α and connexin 43 mRNA,C6 cells were treated with 5 μg/mL lipopolysaccharide for 3-48 hours.Reverse transcription-PCR showed that the expression of inducible nitric oxide synthase and tumor necrosis factor-α mRNA increased over time,but connexin 43 mRNA levels increased in lipopolysaccharide-stimulated C6 cells at 3 and 6 hours,and then decreased from 12 to 48 hours.Connexin 43 protein expression was detected by immunofluorescence staining,and the protein levels matched the mRNA expression levels.These results suggest that connexin 43 expression is biphasic in lipopolysaccharide-induced neuroinflammation in C6 cells,which may be correlated with the connexin 43 compensatory mechanism. | Ling Liu Zhenping Gao Linbo Zhang Lue Su Guojun Dong Haiyang Yu Jiayi Tian Hang Zhao Yanyan Xu Haiyan Liu | 2012 | Neural Regeneration Research2012，7，25： | 1 |
| 18 | Experimental study of beam-column behaviour of steel single angles 显示文摘 | LIU Yi HUI Linbo | 2008 | Journal of Constructional Steel Research2008，64，： | 1 |
| 19 | Finite element study of steel single angle beam- columns显示文摘 | LIU Yi HUI Linbo | 2010 | Engineering Structures2010，32，： | 1 |
| 20 | Cenozoic plants from Tibet:An extraordinary decade of discovery,understanding and implications显示文摘Plant fossils play an important role in understanding landscape evolution across the Tibetan Region,as well as plant diversity across wider eastern Asia.Within the last decade or so,paleobotanical investigations within the Tibet Region have led to a paradigm shift in our understanding of how the present plateau formed and how this affected the regional climate and biota.This is because:(1)Numerous new taxa have been reported.Of all the Cenozoic records of new plant fossil species reported from the Tibet(Xizang)Autonomous Region 45 out of 63(70%)were documented after 2010.Among these,many represent the earliest records from Asia,or in some cases worldwide,at the genus or family level.(2)These fossils show that during the Paleogene,the region now occupied by the Tibetan Plateau was a globally significant floristic exchange hub.Based on paleobiogeographic studies,grounded by fossil evidence,there are four models of regional floristic migration and exchange,i.e.,into Tibet,out of Tibet,out of India and into/out of Africa.(3)Plant fossils evidence the asynchronous formation histories for different parts of the Tibetan Plateau.During most of the Paleogene,there was a wide east-west trending valley with a subtropical climate in central Tibet bounded by high(>4 km)mountain systems,but that by the early Oligocene the modern high plateau had begun to form by the rise of the valley floor.Paleoelevation reconstructions using radiometrically-dated plant fossil assemblages in southeastern Tibet show that by the earliest Oligocene southeastern Tibet(including the Hengduan Mountains)had reached its present elevation.(4)The coevolution between vegetation,landform and paleoenvironment is evidenced by fossil records from what is now the central Tibetan Plateau.From the Paleocene to Pliocene,plant diversity transformed from that of tropical,to subtropical forests,through warm to cool temperate woodland and eventually to deciduous shrubland in response to landscape evolution from a seasonally humid lowland valley,to a high and dry plateau.(5)Advanced multidisciplinary technologies and novel ideas applied to paleobotanical material and paleoenvironmental reconstructions,e.g.,fluorescence microscopy and paleoclimatic models,have been essential for interpreting Cenozoic floras on the Tibetan Region.However,despite significant progress investigating Cenozoic floras of the Tibetan Region,fossil records across this large region remain sparse,and for a better understanding of regional ecosystem dynamics and management more paleobotanical discoveries and multidisciplinary studies are required. | Zhekun ZHOU Jia LIU Linlin CHEN Robert A.SPICER Shufeng LI Jian HUANG Shitao ZHANG Yongjiang HUANG Linbo JIA Jinjin HU Tao SU | 2023 | Science China Earth Sciences2023，66，2： | 0 |
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