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| 1 | Foveated glasses-free 3D display with ultrawide field of view via a large-scale 2D-metagrating complex显示文摘Glasses-free three-dimensional(3D)displays are one of the game-changing technologies that will redefine the display industry in portable electronic devices.However,because of the limited resolution in state-of-the-art display panels,current 3D displays suffer from a critical trade-off among the spatial resolution,angular resolution,and viewing angle.Inspired by the so-called spatially variant resolution imaging found in vertebrate eyes,we propose 3D display with spatially variant information density.Stereoscopic experiences with smooth motion parallax are maintained at the central view,while the viewing angle is enlarged at the periphery view.It is enabled by a large-scale 2D-metagrating complex to manipulate dot/linear/rectangular hybrid shaped views.Furthermore,a video rate full-color 3D display with an unprecedented 160°horizontal viewing angle is demonstrated.With thin and light form factors,the proposed 3D system can be integrated with off-the-shelf purchased flat panels,making it promising for applications in portable electronics. | Jianyu Hua Erkai Hua Fengbin Zhou Jiacheng Shi Chinhua Wang Huigao Duan Yueqiang Hu Wen Qiao Linsen Chen | 2021 | Light(Science & Applications)2021，10，11： | 14 |
| 2 | Pb isotopic geochemical study on the crustal structure of Tongbaishan显示文摘Pb isotopic composition of the Tongbai complex, distributed in the Tongbaishan to the west of the Dabieshan, ranges between the Dabie core complex and the Dabie ultral-high pressure (UHP) metamorphic complex, the latter having more radiogenic Pb isotopic composition than the former. Granites from the Jigongshan pluton, which intruded mainly into the Tongbai complex, are distinct from the Tongbai complex but similar to the Dabie core complex in Pb isotopic composition, showing that the magma of the Jigongshan granites was derived from the partial melting of the Dabie core complex. According to Pb isotopic compositional variation model in the vertical crustal section and magma source from the Jigongshan pluton, it is suggested that the Tongbai complex was an upper rock serial of the Dabie core complex, which is beneath the Dabie UHP metamorphic complex in the crustal structure of the Tongbai-Dabie orogenic belt. The Tongbai complex was not well preserved in the Dabie area due to the high exhumed crustal section. However, the crustal section in the Tongbai area was exhumed less than that in the Dabie area, and the deep crust in the Tongbai area still contains the basement composition similar to the Dabie core complex. Therefore, the crustal basements from the Dabie to Tongbai areas are united. The present distribution of the basement blocks in different locations of the Tongbai-Dabie orogenic belt reflects different exposure of the crustal section. | ZHANG Hongfei, ZHANG Benren, ZHONG Zenqiu, SOU Shutian, ZHANG Haizu and WANG Linsen(China University of Geosciences, Wuhan 430074, China) | 2003 | Progress in Natural Science:Materials International2003，13，1： | 10 |
| 3 | A Bio-Inspired Biped Water Running Robot Incorporating the Watt-I Planar Linkage Mechanism显示文摘 | Linsen Xu Tao Mei Xianming Wei Kai Cao Mingzhou Luo | 2013 | Journal of Bionic Engineering2013，10，4： | 10 |
| 4 | Protective effects of transplanted neural stem cells on the brain of Alzheimer’s disease rats显示文摘BACKGROUND: To date, no drugs are able to halt the progression of Alzheimer's disease (AD). Neural stem cells (NSCs) transplantation has been widely used to treat AD, but the mechanism of AD treatment remains unclear. OBJECTIVE: To observe changes in protein and factors in the hippocampus and frontal lobe of AD rats following NSCs transplantation, and to understand mechanism of action of NSCs transplantation in AD treatment. DESIGN, TIME AND SETTING: A randomized, controlled animal study was conducted at the First Clinical Hospital, Jilin University, China from July 2007 to March 2009. MATERIALS: NSCs were harvested from the hippocampus of 10 E16 Wistar rats. METHODS: A total of 57 male adult Wistar rats were equally and randomly divided into normal control, AD model and NSCs groups. AD models were established in the AD model and NSCs groups by bilateral removal of hippocampus. At 2 weeks postsurgery, NSCs were transplanted into the hippocampus of rats from the NSCs group. MAIN OUTCOME MEASURES: Protein levels were measured in the hippocampus of rats from normal control, NSCs and AD model groups using proteomics. Expression of choline acetyl transferase mRNA, glial fibrillary acidic protein and S100β was measured in the hippocampus and frontal lobe of rats using in situ hybridization and immunohistochemistry. RESULTS: Expression of choline acetyl transferase mRNA, heat shock protein 70, heat shock protein 90, F-actin and actin was significantly higher in the NSCs group compared with AD model group. Glial fibrillary acidic protein and S100β expression was less in the NSCs group compared with AD model group. CONCLUSIOIN: NSCs implanted into the brain may generate new neural cells, which can relieve damage to the cholinergic system and resist apoptosis. NSCs transplantation plays a protective role in the cholinergic system in the AD rats to some extent. | Yan Zhan Dihui Ma Yu Zhang Ming Chang Linsen Hu | 2010 | Neural Regeneration Research2010，5，11： | 9 |
| 5 | Granulite Genesis and Tectonic Evolution in Tongbai Area:Single Zircon Evaporation Ages and Nd Isotopic Geochemistry显示文摘INTRODUCTIONTongbaiareainCentralChinaisanimportantregionforstudyinggenesisrelationbetweenQinlingorogenicbeltandDabieorogenicb... | Zhang Hongfei Gao Shan Zhang Li Zhong Zengqiu Ling Wenli Wang Linsen Faculty of Earth Sciences, China University of Geosciences, Wuhan 430074 | 1998 | Journal of Earth Science1998，17，3： | 6 |
| 6 | Improved dissolution and oral absorption by co-grinding active drug probucol and ternary stabilizers mixtures with planetary beads-milling method显示文摘The objective of this work is to construct a nanosuspension drug delivery system of probucol,a BCS II drug,in order to improve its dissolution and oral bioavailability.The wet milling procedure using planetary beads-milling equipment was utilized to grind the raw probucol to ultrafine nanoparticle/nanocrystal aqueous suspension that was further solidified by freeze-drying process.Cellulose derivatives of different substitution groups and molecular weights,including HPMC,HPC,and MC,were evaluated as the primary stabilizer of probucol nanosuspension.Ternary stabilizers system composed of a primary stabilizer(cellulose derivative,i.e.HPC),a nonionic surfactant(Pluronic R F68),and an anionic surfactant(SDS)was employed to obtain probucol nanosuspension of finer particle size and enhanced dissolution in aqueous media.The probucol nanosuspension with good physical stability showed no obvious change of particle size even after storing over 7 d at 4°C or 25°C.The solidified probucol nanosuspension with trehalose as the cryoprotectant showed the highest dissolution rate(>60%at 2 h)compared to other cryoprotectant.The in vivo pharmacokinetic evaluation indicated about 15-folds higher AUC value of the probucol nanosuspension compared to that of coarse probucol suspension after oral administration to rats.The probucol nanosuspension prepared by wet-milling and ternary stabilizers system may find wide applications for improving the dissolution and oral absorption of water-insoluble drugs. | Fang Li Linsen Li Shaoning Wang Yan Yang Jia Li Dongchun Liu Sijie Zhang Siling Wang Hui Xu | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，6： | 5 |
| 7 | A review of the scalable nano-manufacturing technology for flexible devices显示文摘 | Wenbin HUANG Xingtao YU Yanhua LIU Wen QIAO Linsen CHEN | 2017 | Frontiers of Mechanical Engineering2017，12，1： | 4 |
| 8 | Engineering optimization approach of nonaqueous electrolyte for sodium ion battery with long cycle life and safety显示文摘Electrolyte design strategies are closely related to the capacities, cycle life and safety of sodium–ion batteries. In this study, we aimed to optimize electrolyte with the focus on engineering aspects. The basic physicochemical properties including ionic conductivity, viscosity,wettability and thermochemical stability of the electrolytes using Na PF6 as the solute and the mixed solvent with different components of EMC,DMC or DEC in PC or EC were systematically measured. Ah pouch cell with NaNi_(1/3)Fe_(1/3)Mn_(1/3)O_(2)/hard carbon electrodes was used to evaluate the performance of the prepared electrolytes. By using the Inductive Coupled Plasma Emission Spectrometer(ICP), X-ray photoelectron spectroscopy(XPS), Thermogravimetric-differential scanning calorimetry(TG-DSC) and Accelerating Rate Calorimeter(ARC), we show that an optimized electrolyte can effectively promote the formation of a protective interfacial layer on two electrodes, which not only retards parasitic reactions between the electrodes and electrolyte but also suppresses dissolution of metal ions from the cathode. With an optimized electrolyte, a NaNi_(1/3)Fe_(1/3)Mn_(1/3)O_(2)/hard carbon cell can attain 56.16% capacity retention under the low temperature of -40℃, and can be able to retain 80%capacity retention after more than 2500 cycles while presenting excellent thermal safety. | Haiying Che Xinrong Yang Yan Yu Chaoliang Pan Hong Wang Yonghong Deng Linsen Li Zi-Feng Ma | 2021 | Green Energy & Environment2021，6，2： | 4 |
| 9 | Chaperone proteins identified from synthetic proteasome inhibitor-induced inclusions in PC12 cells by proteomic analysis显示文摘女伴蛋白质在 Lewy 身体是重要的,但是女伴蛋白质的侧面不完全地被解开。Proteomic 分析被用来为进一步的学习决定蛋白质候选人。这里,从导致代理人的包括识别潜在的女伴蛋白质,我们执行了包括在为 48 h 暴露于 10 M 希腊语的第二十三个字母的 PC12 房间形成了的导致的人工地合成的 proteasome 禁止者(希腊语的第二十三个字母) 的 proteomic 分析。用通过指纹对多重蛋白质数据库寻找了的肽质量的生物化学的分别, 2-D 电气泳动,和鉴定,我们反复从导致希腊语的第二十三个字母的包括识别了八可再现的女伴蛋白质。这些, 58 kDa 葡萄糖调整了蛋白质, 75 kDa 葡萄糖调整了蛋白质,并且钙绑定蛋白质 1 是最新识别了。其它五被报导了是 Lewy 身体的一致部件。这些调查结果建议三潜在的女伴蛋白质可能在 proteasome 抑制下面在 PC12 房间被招募到导致希腊语的第二十三个字母的包括。 | Xing'an Li Yingjiu Zhang Yihong Hu Ming Chang Tao Liu Danping Wang Yu Zhang Lei Zhang Linsen Hu | 2008 | Acta Biochimica et Biophysica Sinica2008，40，5： | 4 |
| 10 | The Inhibition Effect of Tert-Butyl Alcohol on the TiO_2 Nano Assays Photoelectrocatalytic Degradation of Different Organics and Its Mechanism显示文摘The inhibition effect of tert-butyl alcohol(TBA), identified as the·OH radical inhibitor, on the TiO_2 nano assays(TNA) photoelectrocatalytic oxidation of different organics such as glucose and phthalate was reported. The adsorption performance of these organics on the TNA photoelectrode was investigated by using the instantaneous photocurrent value, and the degradation property was examined by using the exhausted reaction. The results showed that glucose exhibited the poor adsorption and easy degradation performance, phthalate showed the strong adsorption and harddegradation, but TBA showed the weak adsorption and was the most difficult to be degraded. The degradation of both glucose and phthalate could be inhibited evidently by TBA. But the effect on glucose was more obvious. The different inhibition effects of TBA on different organics could be attributed to the differences in the adsorption and the degradation property. For instance, phthalate of the strong adsorption property could avoid from the capture of·OH radicals by TBA in TNA photoelectrocatalytic process. | Xuejin Li Jinhua Li Jing Bai Yifan Dong Linsen Li Baoxue Zhou | 2016 | Nano-Micro Letters2016，8，3： | 4 |
| 11 | Myelopoiesis during Zebrafish Early Development显示文摘Myelopoiesis 是包括单核白血球 / 巨噬细胞和 granulocytes 生产 myeloid 房间的所有类型的过程。Myeloid 房间被知道表明象改变的有免疫力的监视和织物那样的大量活动。在 myeloid 房间开发和他们的功能的不规则与发作和象白血病那样的许多人的混乱的前进为伙伴所知。在过去的十年,广泛的研究在各种各样的模型有机体被执行了阐明与这些努力将产出进治疗可译的知识为的希望位于 myelopoiesis 下面的分子的机制联系了疾病。Zebrafish 最近为学习 myelopoiesis 作为一个突出的动物模型出现了,特别在早 embryogenesis 期间,主要由于它象透明胚胎的身体和外部开发那样的唯一的性质。这评论介绍在关于 zebrafish myelopoiesis 的最近的研究进步的 zebrafish 研究和焦点使用的方法论。 | Jin Xu Linsen Du Zilong Wen | 2012 | Journal of Genetics and Genomics2012，39，9： | 4 |
| 12 | Pb Isotope Mapping in the Tongbai-Dabie Orogenic Belt, Central China显示文摘摘要:在华中的 Tongbai-Dabie orogenic 带是在 Yangtze 和诺思中国 cratons 之间的 collisional 带的部分。它代表之一最广泛超离频压力(UHP ) 并且高压(HP ) 在世界上的变形岩石。在这个区域印射的 Pb 同位素是一个重要方法抑制外壳的结构和构造进化并且在垂直的构造的栈以内识别构造边界。把 Dabie 的作文基于 Pb 同位素建筑群( DBC ), Tongbai 建筑群( TBC ), UHP 和 HP 变形岩石和联系 foliated 花岗石,从北方 Huaiyang ( NHY )的更低的变形岩石在 Tongbai-Dabie orogenic 的构造的带,和白垩纪花岗石系上带子,我们决定了 Tongbai-Dabie orogenic 带的 Pb 同位素 geochemical 地图。Pb 同位素作文在每地质的身体或 lithotectonic 单位以内是类似的 Pb 同位素地图表演,而是不同 lithotectonic 单位的 Pb 同位素作文在 Tongbai-Dabie orogenic 带显示出系统的变化。NHY 构造的带在 Pb 同位素作文与 Tongbai-Dabie UHP-HP 变形的带强烈形成对照。沿着 Xiaotian-Mozitan 的线指责,这被建议, Tongbai-Dabie UHP 和 HP 的北方限制变形岩石,代表一条重要构造边界。在 Tongbai-Dabie HP-UHP 变形的带以内,到 Xiaotian-Mozitan 差错的南方,以在不同主要 lithotectonic 单位之中的不同 lithotectonic 单位和空间关系的 Pb 同位素作文的垂直变化被抑制了。 | ZHANG Li ZHONG Zengqiu WANG Linsen Zhang Benren | 2008 | Acta Geologica Sinica(English Edition)2008，82，1： | 3 |
| 13 | Geochemical Characteristics of Pb Isotope of High-Pressure Metamorphic Rocks and Foliated Granites from HP Unit of Tongbai-Dabie Orogenic Belt显示文摘Whole-rock Pb isotopic compositions of the high-pressure (HP) metamorphic rocks, consisting of two-mica albite gneisses and eclogites, and foliated granites from the HP metamorphic unit of the Tongbai-Dabie orogenic belt are firstly reported in this paper. The results show that the HP metamorphic rocks in different parts of this orogenic belt have similar Pb isotopic compositions. The two- mica albite gneisses have 206 Pb/ 204 Pb=17.657-18.168, 207 Pb/ 204 Pb=15.318-15.573, 208 Pb/ 204 Pb=38.315-38.990, and the eclogites have 206 Pb/ 204 Pb=17.599-18.310, 207 Pb/ 204 Pb=15.465- 15.615 , 208 Pb/ 204 Pb=37.968-39.143. The HP metamorphic rocks are characterized by upper crustal Pb isotopic composition. Although the Pb isotopic composition of the HP metamorphic rocks partly overlaps that of the ultrahigh-pressure (UHP) metamorphic rocks, as a whole, the former is higher than the latter. The high radiogenic Pb isotopic composition for the HP metamorphic rocks confirms that the subducted Yangtze continental crust in the Tongbai-Dabie orogenic belt has the chemical structure of increasing radiogenic Pb isotopic composition from lower crust to upper crust. The foliated granites, intruded in the HP metamorphic rocks post the HP/UHP metamorphism, have 206 Pb/ 204 Pb=17.128-17.434, 207 Pb/ 204 Pb=15.313-15.422 and 208 Pb/ 204 Pb=37.631-38.122, which are obviously different from the Pb isotopic compositions of the HP metamorphic rocks but similar to those of the UHP metamorphic rocks and the foliated garnet-bearing granites in the UHP unit. This shows that the foliated granites from the HP and UHP units have common magma source. Combined with the foliated granites having the geochemical characteristics of A-type granites, it is suggested that the magma for the foliated granites in the UHP and HP unit would be derived from the partial melting of the retrometamorphosed UHP metamorphic rocks exhumed into middle to lower crust, and partial magmas were intruded into the HP unit. | Zhang Li Zhang Hongfei Zhong Zengqiu Zhang Benren Wang Linsen Faculty of Earth Sciences, China University of Geosciences, Wuhan 430074 | 2003 | Journal of China University of Geosciences2003，14，4： | 3 |
| 14 | Lipids and membrane-associated proteins in autophagy显示文摘Autophagy is essential for the maintenance of cellular homeostasis and its dysfunction has been linked to various diseases.Autophagy is a membrane driven process and tightly regulated by membrane-associated proteins.Here,we summarized membrane lipid composition,and membrane-associated proteins relevant to autophagy from a spatiotemporal perspective.In particular,we focused on three important membrane remodeling processes in autophagy,lipid transfer for phagophore elongation,membrane scission for phago-phore closure,and autophagosome-lysosome membrane fusion.We discussed the significance of the discoveries in this field and possible avenues to follow for future studies.Finally,we summarized the membrane-associated biochemical techniques and assays used to study membrane properties,with a discussion of their applications in autophagy. | Linsen Li Mindan Tong Yuhui Fu Fang Chen Shen Zhang Hanmo Chen Xi Ma Defa Li Xiaoxia Liu Qing Zhong | 2021 | Protein & Cell2021，12，7： | 3 |
| 15 | The onset of deep recycling of supracrustal materials at the Paleo-Mesoarchean boundary显示文摘The recycling of supracrustal materials, and in particular hydrated rocks, has a profound impact on mantle composition and thus on the formation of continental crust, because water modifies the physical properties of lithological systems and the mechanisms of partial melting and fractional fractionation. On the modern Earth, plate tectonics offers an efficient mechanism for mass transport from the Earth’s surface to its interior, but how far this mechanism dates back in the Earth’s history is still uncertain. Here, we use zircon oxygen(O) isotopes to track recycling of supracrustal materials into the magma sources of early Archean igneous suites from the Kaapvaal Craton, southern Africa. The mean δ^(18)O values of zircon from TTG(tonalite–trondhjemite–granodiorite) rocks abruptly increase at the Paleo-Mesoarchean boundary(ca.3230 million years ago;Ma), from mantle zircon values of 5‰–6‰ to approaching 7.1‰, and this increase occurs in ≤3230 Ma rocks with elevated Dy/Yb ratios. The^(18)O enrichment is a unique signature of low-temperature water–rock interaction on the Earth’s surface. Because the later phase was emplaced into the same crustal level as the older one and TTG magmas would derive from melting processes in the garnet stability field(>40 km depth), we suggest that this evident shift in TTG zircon O isotopic compositions records the onset of recycling of the mafic oceanic crust that underwent seawater hydrothermal alteration at low temperature. The onset of the enhanced recycling of supracrustal materials may also have developed elsewhere in other Archean cratons and reflects a significant change in the tectonic realm during craton formation and stabilization, which may be important processes for the operation of plate tectonics on early Earth. | Xiaolei Wang Ming Tang Jeff Moyen Di Wang Alfred Kröner Chris Hawkesworth Xiaoping Xia Hangqiang Xie Carl Anhaeusser Axel Hofmann Junyong Li Linsen Li | 2022 | National Science Review2022，9，3： | 3 |
| 16 | Spectroscopic Analysis on the Effect of Temperature on Kunitz Domain 1 of Human Tissue Factor Pathway Inhibitor-2显示文摘Kunitz 领域 1 人的织物因素 pathwayinhibitor-2 (hTFPI-2/KD1 ) 的符合构造被 Fourier 变换学习了红外线的光谱学,圆形的二色性,和拉曼光谱学。hTFPI-2/KD1 在详细 conformational 揭示的 Fouriertransform 红外线的光谱学,圆形的二色性和拉曼光谱学观察的激烈的蛋白质改变的 25 ° C .The 包含了近似 17%alpha-helices,24% 贝它海滨, 46% 随机的卷, 13% 贝它拐弯,和二种二硫键(gggand tgt ) ,这被发现那 hTFPI-2/KDlwas 热地稳定。然而, KD1 能在高温度形成一种中间的形式,当温度被降低时,然后回到它的正常符合构造。活动试金也证明 thathTFPI-2/KDl 能在为 5min 被加热到 80 ° C 以后在胞质素上保留它的禁止的活动。 | Chenqi ZHANG Desheng KONG Xingang LIU Xiaomin YAN Linsen DAI Duan MA | 2007 | Acta Biochimica et Biophysica Sinica2007，39，6： | 3 |
| 17 | Expression and characterization of Kunitz domain 3 and C-terminal of human tissue factor pathway inhibitor-2显示文摘人的织物因素小径 inhibitor-2 (hTFPI-2 ) 是一个丝氨酸朊酶禁止者,它的禁止的活动被肝磷脂提高。Kunitz 领域 3 并且 hTFPI-2 (hTFPI-2/KD3C ) 的 C 终端,向肝磷脂钙举办这项活动,成功地在 Pichia pastoris 被表示了并且由 SP-Sepharose 和 heparin-Sepharose 层析净化了。转变红外线的光谱学(FTIR )(CD ) ,拉曼光谱学,和圆形的二色性试验的 Fourier 结果暗示 hTFPI-2/KD3C 包含了螺旋和 -strand, 的小内容但是大量随机的卷和二种二硫化物契约, gauche-gauche-gauche (ggg ) 和 trans-gauche-trans (tgt ) 。有肝磷脂钙的 hTFPI-2/KD3C 的相互作用被 CD 调查。肝磷脂钙在 hTFPI-2/KD3C 导致了海滨到取决于 hTFPI-2/KD3C 和肝磷脂钙的比率的不同程度,这被发现。 | Lina Zhu Jiping Wang Jingui Mu Huijun Wang Chenqi Zhang Jue Wang Xingang Liu Xiaomin Yan Linsen Dai Duan Ma | 2009 | Acta Biochimica et Biophysica Sinica2009，41，11： | 3 |
| 18 | Adaptive Fuzzy Sliding Mode Controller with Nonlinear Observer for Redundant Manipulators Handling Varying External Force显示文摘 | Jun He Minzhou Luo Qingqing Zhang Jianghai Zhao Linsen Xu | 2016 | Journal of Bionic Engineering2016，13，4： | 3 |
| 19 | Spatial variation in grain-size population of surface sediments from northern Bering Sea and western Arctic Ocean: Implications for provenance and depositional mechanisms显示文摘In general,sediments in nature comprise populations of various diameters.Accurate information regarding the sources and depositional mechanisms of the populations can be obtained through their temporal and spatial comparisons.In this study,the grain size distribution of surface sediments from the Bering Sea and western Arctic Ocean were fitted and partitioned into populations using a log-normal distribution function.The spatial variations in the populations indicate differences in their sources and deposition mechanisms.The sediments on most of the Bering Sea Shelf originated from the Yukon River,and were transported westward by waves and currents.However,the presence of a coarser population outside Anadyr Bay was the result of Anadyr River transport.Additionally,a northward transport trend of fine suspended particles was observed on the west side of the Bering Sea Shelf.The sediments in Hope Valley in the south Chukchi Sea also originated from the Yukon River.The coarser population on the central Chukchi Sea Shelf originated from coast of Alaska to the east,not the Yukon River,and was transported by sea ice and bottom brine water.The populations of sediments from the Chukchi Basin and the base of the Chukchi Sea Slope are the result of sea ice and eddy action.Surface sediments from the western high Arctic Ocean predominantly comprised five populations,and two unique populations with mode diameters of 50–90μm and 200–400μm,respectively,were ubiquitous in the glacial and interglacial sediments.It was difficult to distinguish whether these two populations originated from sea ice or icebergs.Therefore,caution should be exercised when using either the>63μm or>250μm fractions in sediments as a proxy index for iceberg and ice sheet variation in the high Arctic Ocean. | WANG Weiguo YANG Jichao ZHAO Mengwei DONG Linsen JIANG Min HUANG Erhui | 2020 | Advances in Polar Science2020，31，3： | 2 |
| 20 | miRNA-dysregulation associated with tenderness variation induced by acute stress in Angus cattle显示文摘miRNAs are a class of small, single-stranded, non-coding RNAs that perform post-transcriptional repression of target genes by binding to 3' untranslated regions. Research has found that miRNAs involved in the regulation of many metabolic processes. Here we uncovered that the beef quality of Angus cattle sharply diversified after acute stress. By performing miRNA microarray analysis, 13 miRNAs were significantly differentially expressed in stressed group compared to control group. Using a bioinformatics method, 135 protein-coding genes were predicted as the targets of significant differentially expressed miRNAs. Gene Ontology (GO) term and Ingenuity Pathway Analysis (IPA) mined that these target genes involved in some important pathways, which may have impact on meat quality and beef tenderness. | Chunping Zhao Fei Tian Ying Yu George Liu Linsen Zan M Scott Updike Jiuzhou Song | 2012 | Journal of Animal Science and Biotechnology2012，3，2： | 2 |
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