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| 1 | Natural Variation in OsPRR37 Regulates Heading Date and Contributes to Rice Cultivation at a Wide Range of Latitudes显示文摘标题日期和光周期敏感是决定米饭改编到大量 geographicenvironments 的基本特点。由印射的量的特点地点(QTL ) 和候选人基因分析使用整个染色体重新定序,我们 foundthat Oryza sativa 伪反应 Regulator37 (OsPRR37;此后 PRR37 ) 为早 heading7-2 (EH7-2 ) 负责从迟了标题的米饭 Milyang23 (M23 ) 和早标题的米饭 H143 的一个十字被识别的 /Heading date2 (Hd2 ) QTL。在 CCT 的不变地保存的氨基酸的 H143 containsa 错误感觉变化(CONSTANS,共同喜欢,并且 TOC1 ) PRR37 protein.In 的领域世界米饭收集, nonfunctional PRR37 等位基因的不同类型在许多欧洲、亚洲的米饭栽培变种被发现。尤其是,在自然长天的条件下面极其早怀有 Ghd7/Hd4 和 PRR37/Hd2 花的 nonfunctional 等位基因的装饰用的梨树变化,并且被使适应米饭耕作的极北的区域,多达 53 ?? ? 攠潸祣瑳 ????? 楶牴 ??? 啅?? | Bon-Hyuk Koo Soo-Cheul Yoo Joon-Woo Park Choon-Tak Kwon Byoung-Doo Lee Gynheung An Zhanying Zhang linjie Li Zichao Li Nam-Chon Paek | 2013 | Molecular Plant2013，6，6： | 42 |
| 2 | Ankylosing spondylitis: etiology, pathogenesis, and treatments显示文摘Ankylosing spondylitis(AS), a common type of spondyloarthropathy, is a chronic inflammatory autoimmune disease that mainly affects spine joints, causing severe, chronic pain;additionally, in more advanced cases, it can cause spine fusion. Significant progress in its pathophysiology and treatment has been achieved in the last decade. Immune cells and innate cytokines have been suggested to be crucial in the pathogenesis of AS, especially human leukocyte antigen(HLA)?B27 and the interleukin?23/17 axis.However, the pathogenesis of AS remains unclear. The current study reviewed the etiology and pathogenesis of AS, including genome-wide association studies and cytokine pathways. This study also summarized the current pharmaceutical and surgical treatment with a discussion of future potential therapies. | Wei Zhu Xuxia He Kaiyuan Cheng Linjie Zhang Di Chen Xiao Wang Guixing Qiu Xu Cao Xisheng Weng | 2019 | Bone Research2019，7，3： | 30 |
| 3 | Kinetics of the accumulation of group 2 innate lymphoid cells in IL-33-induced and IL-25-induced murine models of asthma:a potential role for the chemokine CXCL16显示文摘ILC2s are implicated in asthma pathogenesis, but little is known about the mechanisms underlying their accumulation in airways.We investigated the time course of ILC2 accumulation in different tissues in murine models of asthma induced by a serial per-nasalchallenge with ovalbumin (OVA), house dust mice (HDM), IL-25 and IL-33 and explored the potential roles of ILC2-attractingchemokines in this phenomenon. Flow cytometry was used to enumerate ILC2s at various time points. The effects of cytokines andchemokines on ILC2 migration were measured in vitro using a chemotaxis assay and in vivo using small animal imaging. Comparedwith saline and OVA challenge, both IL-25 and IL-33 challenge alone induced significant accumulation of ILC2s in the mediastinallymph nodes, lung tissue and bronchoalveolar lavage fluid of challenged animals, but with a distinct potency and kinetics. In vitro,IL-33 and CXCL16, but not IL-25 or CCL25, directly induced ILC2 migration. Small animal in vivo imaging further confirmed that asingle intranasal provocation with IL-33 or CXCL16 was sufficient to induce the accumulation of ILC2s in the lungs followinginjection via the tail vein. Moreover, IL-33-induced ILC2 migration involved the activation of ERK1/2, p38, Akt, JNK and NF-κB, whileCXCL16-induced ILC2 migration involved the activation of ERK1/2, p38 and Akt. These data support the hypothesis that epitheliumderived IL-25 and IL-33 induce lung accumulation of ILC2s, while IL-33 exerts a direct chemotactic effect in this process. AlthoughILC2s express the chemokine receptors CXCR6 and CCR9, only CXCL16, the ligand of CXCR6, exhibits a direct chemoattractanteffect. | Yan Li Shihao Chen Yafei Chi Yiran Yang Xiwen Chen Huating Wang Zhe Lv Jingjing Wang Linjie Yuan Ping Huang Kewu Huang Chris JCorrigan Wei Wang Sun Ying | 2019 | Cellular & Molecular Immunology2019，16，1： | 13 |
| 4 | Direct generation of an ultrafast vortex beam in a CVD-graphene-based passively mode-locked Pr:LiYF4 visible laser显示文摘We report on the direct generation of passively mode-locked vortex lasers in the visible spectral region, for the first time to the best of our knowledge, using a Pr :Li YF4(Pr:YLF) crystal as the gain medium. A stable mode-locked TEM00 mode has been achieved with a maximum average output power of 75 m W using a graphene saturable absorber mirror. The mode-locked pulse width is measured to be as short as about 73.4 ps at a repetition rate of about 140 MHz, and the laser wavelength is at about 721 nm with spectral width of about 0.5 nm. By slightly misaligning the laser resonator, a first-order Laguerre-Gaussian mode(LG0,1) has also been obtained with output power reduced to about 22 m W. The achieved LG0,1 mode has been verified via a home made improved Fizeau interferometer. This work provides a simple and universal method for direct generation of an ultrafast vortex laser,which can be readily extended to other spectral regions by using different laser gain mediums. | Nan Li Junjie Huang Bin Xu Yaqi Cai Jie Lu Linjie Zhan Zhengqian Luo Huiying Xu Zhiping Cai Weiwei Cai | 2019 | Photonics Research2019，7，11： | 9 |
| 5 | Physiological effects of weightlessness: countermeasure system development for a long-term Chinese manned spaceflight显示文摘The Chinese space station will be built around 2020. As a national space laboratory, it will offer unique opportunities for studying the physiological effects of weightlessness and the efficacy of the countermeasures against such effects. In this paper, we described the development of countermeasure systems in the Chinese space program. To emphasize the need of the Chinese space program to implement its own program for developing countermeasures, we reviewed the literature on the negative physiological effects of weightlessness, the challenges of completing missions, the development of countermeasure devices, the establishment of countermeasure programs, and the efficacy of the countermeasure techniques in American and Russian manned spaceflights. In addition, a brief overview was provided on the Chinese research and development on countermeasures to discuss the current status and goals of the development of countermeasures against physiological problems associated with weightlessness. | Linjie Wang Zhili Li Cheng Tan Shujuan Liu Jianfeng Zhang Siyang He Peng Zou Weibo Liu Yinghui Li | 2019 | Frontiers of Medicine2019，13，2： | 9 |
| 6 | Formation mechanism of a smooth, defectfree surface of fused silica optics using rapid CO2 laser polishing显示文摘Surface defects introduced by conventional mechanical processing methods can induce irreversible damage and reduce the service life of optics applied in high-power lasers.Compared to mechanical processing,laser polishing with moving beam spot is a noncontact processing method,which is able to form a defect-free surface.This work aims to explore the mechanism of forming a smooth,defect-free fused silica surface by high-power density laser polishing with coupled multiple beams.The underlying mechanisms of laser polishing was revealed by numerical simulations and the theoretical results were verified by experiments.The simulated polishing depth and machined surface morphology were in close agreement with the experimental results.To obtain the optimized polishing quality,the effects of laser polishing parameters(e.g.overlap rate,pulse width and polishing times)on the polishing quality were experimentally investigated.It was found that the processing efficiency of fused silica materials by carbon dioxide(CO2)laser polishing could reach 8.68 mm2 s−1,and the surface roughness(Ra)was better than 25 nm.Besides,the cracks on pristine fused silica surfaces introduced by initial grinding process were completely removed by laser polishing to achieve a defect-free surface.The maximum laser polishing rate can reach 3.88μm s−1,much higher than that of the traditional mechanical polishing methods.The rapid CO2 laser polishing can effectively achieve smooth,defect-free surface,which is of great significance to improve the surface quality of fused silica optics applied in high-power laser facilities. | Linjie Zhao Jian Cheng Mingjun Chen Xiaodong Yuan Wei Liao Qi Liu Hao Yang Haijun Wang | 2019 | International Journal of Extreme Manufacturing2019，1，3： | 8 |
| 7 | Reduced Graphene Oxide Mediated SnO_2 Nanocrystals for Enhanced Gas-sensing Properties显示文摘SnO2 ereduced graphene oxide (SnO2-rGO) composites were prepared via a hydro-thermal reaction of graphene oxide (GO) and SnCl2·2H2O in the mixed solvent of ethylene glycol and water. During the redox reaction, GO was reduced to rGO while Sn2+ was oxidized to SnO2, uniformly depositing on the surface of rGO sheets. The composites were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), infrared spectra analysis (IR) and transmission electron microscopy (TEM), respectively, and their gas sensing properties were further investigated. Compared with pure SnO2 nanoparticles, the as-prepared SnO2-rGO gas sensor showed much better gas sensing behavior in sensitivity and response-recovery time to ethanol and H2S at low concentrations. Overall, the highly sensitive, quickresponding and low cost SnO2-rGO gas sensor could be potentially applied in environmental monitoring area. | Yanhong Chang Yunfeng Yao Bin Wang Hui Luo Tianyi Li Linjie Zhi | 2013 | Journal of Materials Science & Technology2013，29，2： | 7 |
| 8 | 16 × 16 silicon Mach–Zehnder interferometer switch actuated with waveguide microheaters显示文摘We experimentally demonstrate a 16 × 16 reconfigurably nonblocking optical switch fabric using a Benes architecture. The switch fabric consists of 56 2 × 2 Mach–Zehnder interferometer based elementary switches, with each integrated with a pair of waveguide microheaters. The average on-chip insertion loss is ~5.2 dB for both of the 'all-cross' and the 'all-bar' states, with a loss variation of 1 dB over all routing paths. The cross talk for all switching states is better than -30 d B. The switching time of the switch element is about 22 μs. The switching functionality is verified by transmission of a 40 Gb∕s quadrature phase-shift keying optical signal. | Shuoyi Zhao Liangjun Lu Linjie Zhou Dong Li Zhanzhi Guo Jianping Chen | 2016 | Photonics Research2016，4，5： | 7 |
| 9 | Molecular Framework for Auxin-Controlled Hlomeostasis-of Shoot Stem Cells in Arabidopsis显示文摘 | Linjie Luo Jian Zengg Haijun Wu Zhaoxia Tian Zhong Zhao | 2018 | Molecular Plant2018，11，7： | 7 |
| 10 | Human CMTM2/CKLFSF2 enhances the ligand-induced transactivation of the androgen receptor显示文摘CKLF (chemokine-like factor)-like MARVEL (MAL and related proteins for vesicle trafficking and mem-brane link domain) transmembrane domain containing (CMTM) is a novel gene family. One member of this family, CMTM2, also named chemokine-like factor superfamily 2 (CKLFSF2), is expressed highly in the testis and moderately in the prostate, marrow and peripheral blood cells. However, the function of human CMTM2 remains unknown. Here, we found that CMTM2 was upregulated in 5α-dihydrotestos- terone (DHT)-treated LNCaP cells. We investigated the relationship between CMTM2 and the androgen receptor. Our results showed that CMTM2 enhanced DHT-mediated androgen receptor (AR) transacti-vation and the expression of prostate specific antigen (PSA). We also observed that CMTM2 enhanced the AR protein level, which was reversed by silencing endogenous CMTM2 expression, which sug-gested that CMTM2 might play an important role in maintaining the AR protein level. We also found that CMTM2 suppressed Akt activation. A previous study showed that Akt could phosphorylate AR at Ser210 and Ser790 and lead to AR ubiquitylation and degradation as well as suppression of AR activity. Taken together, suppressing Akt activation and increasing the AR protein level might be one of the mechanisms for the CMTM2-mediated enhancement of AR transactivation. | LIU DaZhen YIN CaiHua ZHANG YingMei TIAN LinJie LI Ting LI Dan MA DaLong GUO YingLu WANG Ying | 2009 | Chinese Science Bulletin2009，54，6： | 7 |
| 11 | Conditional Similarity Solutions of the Boussinesq Equation显示文摘The direct method proposed by Clarkson and Kruskal is modified to obtain some conditional similarity solutions of a nonlinear physics model. Taking the (1+ 1 )-dimensional Boussinesq equation as a simple example, six types of conditional similarity reductions are obtained. | TANGXiao-Yan LINJi 等 | 2001 | Communications in Theoretical Physics2001，35，4： | 6 |
| 12 | Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions显示文摘Brain tumors are dynamic complex ecosystems with multiple cell types.To model the brain tumor microenvironment in a reproducible and scalable system,we developed a rapid three-dimensional(3D)bioprinting method to construct clinically relevant biomimetic tissue models.In recurrent glioblastoma,macrophages/microglia prominently contribute to the tumor mass.To parse the function of macrophages in 3D,we compared the growth of glioblastoma stem cells(GSCs)alone or with astrocytes and neural precursor cells in a hyaluronic acid-rich hydrogel,with or without macrophage.Bioprinted constructs integrating macrophage recapitulate patient-derived transcriptional profiles predictive of patient survival,maintenance of stemness,invasion,and drug resistance.Whole-genome CRISPR screening with bioprinted complex systems identified unique molecular dependencies in GSCs,relative to sphere culture.Multicellular bioprinted models serve as a scalable and physiologic platform to interrogate drug sensitivity,cellular crosstalk,invasion,context-specific functional dependencies,as well as immunologic interactions in a species-matched neural environment. | Min Tang Qi Xie Ryan C.Gimple Zheng Zhong Trevor Tam Jing Tian Reilly L.Kidwell Qiulian Wu Briana C.Prager Zhixin Qiu Aaron Yu Zhe Zhu Pinar Mesci Hui Jing Jacob Schimelman Pengrui Wang Derrick Lee Michael H.Lorenzini Deobrat Dixit Linjie Zhao Shruti B.hargava Tyler E.Miller Xueyi Wan Jing Tang Bingjie Sun Benjamin F.Cravatt Alysson R.Muotri Shaochen Chen Jeremy N.Rich | 2020 | Cell Research2020，30，10： | 6 |
| 13 | Conditional Similarity Reductions of Jimbo—Miwa Equation via the Classical Lie Group Approach显示文摘Recently, the Clarkson and Kruskal direct method has been modified to find new similarity reductions (conditional similarity reductions) of nonlinear systems and the results obtained by the modified direct method cannot be obtained by the current classical and/or non-classical Lie group approach. In this paper, we show that the conditional similarity reductions of the Jimbo-Miwa equation can be reobtained by adding an additional constraint equation to the original model to form a conditional equation system first and then solving the model system by means of the classical Lie group approach. | TANGXiao-Yan LINJi 等 | 2003 | Communications in Theoretical Physics2003，39，1： | 5 |
| 14 | Modeling and optimization of a single-drive push–pull silicon Mach–Zehnder modulator显示文摘We present an equivalent circuit model for a silicon carrier-depletion single-drive push–pull Mach–Zehnder modulator(MZM)with its traveling wave electrode made of coplanar strip lines.In particular,the partialcapacitance technique and conformal mapping are used to derive the capacitance associated with each layer.The PN junction is accurately modeled with the fringe capacitances taken into consideration.The circuit model is validated by comparing the calculations with the simulation results.Using this model,we analyze the effect of several key parameters on the modulator performance to optimize the design.Experimental results of MZMs confirm the theoretical analysis.A 56 Gb/s on–off keying modulation and a 40 Gb/s binary phase-shift keying modulation are achieved using the optimized modulator. | Yanyang Zhou Linjie Zhou Haike Zhu Chiyan Wong Yida Wen Lei Liu Xinwan Li Jianping Chen | 2016 | Photonics Research2016，4，4： | 5 |
| 15 | A comprehensive CFD combustion model for supercritical CFB boilers显示文摘A combustion model of a large-scale supercritical circulati ng fluidized bed (CFB) boiler was developed for comprehensive computational-fluid-dynamics analysis. The model incorporates gas-solid hydrodynamics, coal combustion, heat transfer on heat exchange surfaces in the furnace, and heat transfer between fumace and working medium in the heat transfer tubes. In simulating the dense and dilute phases in the fumace, the gas-solid hydrodynamics is based on the Euler-Euler model and energy-minimization multiscale drag model. Coal combustion entails evaporation, devolatilization, char combustion, gas homoge neous reaction, and pollutant emission. The coefficient ofheat transfer between gas-solid and the waterwall is estimated using the cluster renewal model, and for radiation, the discrete ordinate model is used. Moreover, thermohydraulic processes in the membrane wall are also in eluded in the heat transfer process. The model was successfully applied in simulations of a 350-MW supercritical CFB boiler. Detailed distributions of solids concentration, oxygen, heat flux, and working medium temperature in the boiler furnace are presented. | Linjie Xu Leming Cheng JieqiangJi Qinhui Wang Mengxiang Fang | 2019 | Particuology2019，17，2： | 5 |
| 16 | Exact Solutions of the Coupled KdV system via a Formally Variable Separation Approach显示文摘Most of the nonlinear physics systems are essentially nonintegrable. There is no very good analytical approach to solve nonintegrable system. The variable separation approach is a powerful method in linear physics. In this letter, the formal variable separation approach is established to solve the generalized nonlinear mathematical physics equation. The method is valid not only for integrable models but also for nonintegrable models. Taking a nonintegrable coupled KdV equation system as a simple example, abundant solitary wave solutions and conoid wave solutions are revealed. | LOUSee-Yue LINJi 等 | 2001 | Communications in Theoretical Physics2001，36，2： | 4 |
| 17 | Silicon high-speed binary phase-shift keying modulator with a single-drive push–pull high-speed traveling wave electrode显示文摘We demonstrate binary phase shift keying(BPSK) modulation using a silicon Mach–Zehnder modulator with aπ-phase-shift voltage(Vπ) of-4.5 V.The single-drive push–pull traveling wave electrode has been optimized using numerical simulations with a 3 dB electro-optic bandwidth of 35 GHz.The 32 Gb/s BPSK constellation diagram is measured with an error vector magnitude of 18.9%. | Jinting Wang Linjie Zhou Haike Zhu Rui Yang Yanyang Zhou Lei Liu Tao Wang Jianping Chen | 2015 | Photonics Research2015，3，3： | 4 |
| 18 | Kinetics of nitrobenzene degradation coupled to indigenous microorganism dissimilatory iron reduction stimulated by emulsified vegetable oil显示文摘Widespread contamination by nitrobenzene(NB) in sediments and groundwater requires better understanding of the biogeochemical removal process of the pollutant. NB degradation, coupled with dissimilatory iron reduction, is one of the most efficient pollutant removal methods. However, research on NB degradation coupled to indigenous microorganism dissimilatory iron reduction stimulated by electron donors is still experimental. A model for remediation in an actual polluted site does not currently exist.Therefore, in this study, the dynamics was derived from the Michaelis–Menten model(when the mass ratio of emulsified vegetable oil and NB reached the critical value 91:1). The effect of SO_4^(2-), NO_3^-, Ca^(2+)/Mg^(2+), and the grain size of aquifer media on the dynamics were studied, and the NB degradation dynamic model was then modified based on the most significant factors. Utilizing the model, the remediation time could be calculated in a contaminated site. | Jun Dong Linjie Ding Zifang Chi Jiansen Lei Yan Su | 2017 | Journal of Environmental Sciences2017，29，4： | 4 |
| 19 | Achieving long-cycling sodium-ion full cells in ether-based electrolyte with vinylene carbonate additive显示文摘Application of sodium-ion batteries is suppressed due to the lack of appropriate electrolytes matching cathode and anode simultaneously.Ether-based electrolytes,preference of anode materials,cannot match with high-potential cathodes failing to apply in full cells.Herein,vinylene carbonate(VC)as an additive into NaCF_(3) SO_(3)-Diglyme(DGM)could make sodium-ion full cells applicable without preactivation of cathode and anode.The assembled FeS@C||Na3 V2(PO_(4))_(3)@C full cell with this electrolyte exhibits long term cycling stability and high capacity retention.The deduced reason is additive VC,whose HOMO level value is close to that of DGM,not only change the solvent sheath structure of Na^(+),but also is synergistically oxidized with DGM to form integrity and consecutive cathode electrolyte interphase on Na3 V2(PO_(4))_(3)@C cathode,which could effectively improve the oxidative stability of electrolyte and prevent the electrolyte decomposition.This work displays a new way to optimize the sodium-ion full cell seasily with bright practical application potential. | Juan Shi Lina Ding Yanhua Wan Liwei Mi Linjie Chen Dan Yang Yuxiong Hu Weihua Chen | 2021 | Journal of Energy Chemistry2021，30，6： | 4 |
| 20 | A design method for high fabrication tolerance integrated optical mode multiplexer显示文摘The tapered asymmetric directional coupler has the potential to realize high fabrication tolerance and high transmission efficiency on-chip mode multiplexer.However,the geometry parameter selection of tapered structure remains empirical.In this paper,we propose a design method for the tapered structure based on genetic algorithm.Combined with the adjusted coupling equations and interpolation method,lowtime-cost optimization can be realized.Three mode multiplexers(TE0&TE1,TE0&TE2 and TE0&TE5)are designed by our method.According to simulation results,the insertion loss of the designed devices is lower than 1.8 dB and the crosstalk is lower than-15 dB when the fabrication error is within required range(±10 nm for TE0&TE2 and TE0&TE5,and±20 nm for TE0&TE1)in the bandwidth of 1.5–1.6μm.In addition,the entire optimization process takes only 2 h for each device,which is around the time cost of a single 3 D simulation. | Bitao SHEN Haowen SHU Linjie ZHOU Xingjun WANG | 2020 | Science China(Information Sciences)2020，63，6： | 3 |
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