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| 1 | Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism显示文摘Amycolatopsis mediterranei 被用于 rifamycin 的工业规模生产,它在 antimycobacterial 治疗起一个重要作用。作为类 Amycolatopsis 的首先定序的染色体, 236 715 底配对的包括 10 的紧张 U32 的染色体,最大的原核生物的染色体之一到目前为止曾经被定序。不同于在 streptomycetes 发现的线性拓扑学,这个染色体是圆形的,特别地类似于 Saccharopolyspora erythraea 和奴卡氏菌属 farcinica,在发展史和分类代表他们的靠近的关系。尽管在 A 预言了 9 228 编码蛋白质的基因。mediterranei 染色体 S 与那些分享了 orthologs 的最大的数字。erythraea,它被 Streptomyces coelicolor 而非 N 出人意料地跟随。farcinica,显示不同新陈代谢的特征经由改编演变到多样的生态的壁龛。除类似于那的一个核心区域以外在 streptomycetes 普通,有典型核心特征的一个新奇“伪核心”在非核心区域以内被定义,在 21 从 26 基因为第二等的代谢物生产聚类的总数被定位的地方。位于核心的 rifamycin 生合成基因簇为 rifamycin SV 的变换编码细胞色素 P450 酶必需品到 B,由比作 rifamycin 生产 B 紧张 S699 的高度相应的簇揭示了并且进一步由基因互补证实了。A 的 genomic 信息。mediterranei 表明在看起来复杂的规章的机制的控制下面不仅为各种各样的碳来源和无机的氮混合物的广泛的利用而且为新陈代谢的中介的有效 funneling 安排进第二等的抗菌素合成进程的一个新陈代谢的网络。 | Wei Zhao Yi Zhong Hua Yuan Jin Wang Huajun Zheng Ying Wang Xufeng Cen Feng Xu Jie Bai Xiaobiao Han Gang Lu Yongqiang Zhu Zhihui Shao Han Yan Chen Li Nanqiu Peng Zilong Zhang Yunyi Zhang Wei Lin Yun Fan Zhongjun Qin Yongfei Hu Baoli Zhu Shengyue Wang Xiaoming Ding Guo-Ping Zbao | 2010 | Cell Research2010,20,10: | 10 |
| 2 | Scalable microfabrication of three-dimensional porous interconnected graphene scaffolds with carbon spheres for high-performance all carbon-based micro-supercapacitors显示文摘As one of the most important micro energy storage devices(MESDs),graphene-based micro-supercapacitors(G-MSCs)possess the advantages of excellent flexibility,long cycle life,affordability and high reliability.In most cases,constructing three-dimensional(3D)graphene networks is widely utilized to promote the permeation of electrolyte and enhance the utilization of active materials.In this work,conventional freeze-drying process is utilized in the fabrication of G-MSCs to constitute 3D interconnected networks micro-electrodes,and further by regulating the composition of inks,carbon spheres(CSs)at different mass loadings are introduced into the graphene scaffolds to further increase the active sites of the micro-electrodes.The fabricated all carbon-based MSC with the optimal mass loading of CSs(0.406 mg cm^(-2))exhibits a high specific areal capacitance of 17.01mF cm^(-2)at the scan rate of 10mV s^(-1)and a capacitance retention of 93.14%after 10000 cycles at the scan rate of 500 mV s^(-1).The proposed microfabrication process is facile and fully compatible with modern microtechnologies and will be highly suitable for large-scale production and integration. | Yiming Chen Minghao Guo Liang He Wei Yang Lin Xu Jiashen Meng Xiaocong Tian Xinyu Ma Qiang Yu Kaichun Yang Xufeng Hong Liqiang Mai | 2019 | Journal of Materiomics2019,5,2: | 6 |
| 3 | Chiral Spirocyclic Phosphoric Acids and Their Growing Applications显示文摘Chiral spirocyclic phosphoric acids(SPAs)are introduced in 2010 and have been versatile catalysts capable of promoting a wide range of asymmetric organocatalytic reactions,such as multi-component reactions,Friedel–Crafts reactions,Pictet–Spengler reactions,Fischer indolizations,cycloaddition reactions,desymmetrization reactions,dearomatization reactions,conjugate addition reactions and rearrangement reactions,etc.Moreover,a diverse range of applications in metal-organic cooperative catalysis,organic photoredox catalysis,total synthesis,materials science and molecular recognition are beautifully illustrated.This account summarizes the past decade's advances in this field and highlights the selected but not comprehensive significant achievements. | Xufeng Lin Lei Wang Zhao Han Zhouli Chen | 2021 | Chinese Journal of Chemistry2021,39,4: | 5 |
| 4 | Hydrogen saline is protective for acute lung ischaemia/reperfusion injuries in rats显示文摘 | Jianxin Shi Feng Yao Chenxi Zhong Xufeng Pan Yu Yang Qiang Lin | 2012 | Heart, Lung and Circulation2012,,9: | 1 |
| 5 | Synthesis and properties of a novel UV-curable waterborne hyperbranched polyurethane显示文摘 | Lin Xufeng Zhang Shouyi Qian Jun | 2014 | J Coat Technol Res2014,11,3: | 1 |
| 6 | Molecular iodine-catalyzed one-pot synthesis of substituted quinolines from imines and aldehydes显示文摘 | Lin Xufeng Cui Sunliang Wang Yanguang | 2006 | Tetrahedron Lett2006,47,18: | 1 |
| 7 | Synthesis and biological evaluation of functionalized coumarins as acetylcholinesterase inhibitors显示文摘 | Qiong Shen Quan Peng Jialiang Shao Xufeng Liu Zhishu Huang Xianzhang Pu Lin Ma Yue-Ming Li Albert S.C. Chan Lianquan Gu | 2005 | European Journal of Medicinal Chemistry2005,,: | 1 |
| 8 | Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain显示文摘 | Lin Shu Storlien LH Huang Xufeng | 2000 | Brain Res2000,875,: | 1 |
| 9 | An error con- trol approach to tool path adjustment conforming to the de- formation of thin-walled workpiece显示文摘 | Wan Xiaojin Hua Lin Wang Xufeng | 2011 | International Journal of Machine Tools and Manufacture2011,51,3: | 1 |
| 10 | In-situ selective surface engineering of graphene micro-supercapacitor chips显示文摘Surface modification of graphene oxide(GO)is a powerful strategy to develop its energy density for electrochemical energy storage.However,pre-modified GO always exhibits unsatisfactory hydrophilia and its ink-relevant utilization is extremely limited.Although GO ink is widely utilized in fabricating micro energy storage devices via extrusion-based 3D-printing,simultaneously obtaining satisfactory hydrophilia and high energy density still remains a challenge.In this work,an in-situ surface engineering strategy was employed to enhance the performance of GO micro-supercapacitor chips.Three dimensionally printed GO micro-supercapacitor chips were treated with pyrrole monomer to achieve selective and spontaneous anchoring of polypyrrole on the microelectrodes without affecting interspaces between the finger electrodes.The interface-reinforced graphene scaffolds were edge-welded and exhibited a considerably improved specific capacitance,from 13.6 to 128.4 mF·cm^(-2).These results are expected to provide a new method for improving the performance of micro-supercapacitors derived from GO inks and further strengthen the practicability of 3D printing techniques in fabricating energy storage devices. | Yiming Chen Minghao Guo Lin Xu Yuyang Cai Xiaocong Tian Xiaobin Liao Zhaoyang Wang Jiashen Meng Xufeng Hong Liqiang Mai | 2022 | Nano Research2022,15,2: | 0 |
| 11 | Fabrication and performance of 3D co-continuous magnesium composites reinforced with Ti_(2)AlN_(x) MAX phase显示文摘Magnesium composites reinforced by N-deficient Ti_(2)AlN MAX phase were first fabricated by non-pressure infiltration of Mg into three-dimensional(3D)co-continuous porous Ti_(2)AlN_(x)(x=0.9,1.0)preforms.The relationship between their mechanical properties and micro-structure is discussed with the assessment of 2D and 3D characterization.X-ray diffraction(XRD)and scanning electron microscopy detected no impurities.The 3D reconstruction shows that the uniformly distributed pores in Ti_(2)AlN_(x) preforms are interconnected,which act as infiltra-tion tunnels for the melt Mg.The compressive yield strength and microhardness of Ti_(2)AlN_(0.9)/Mg are 353 MPa and 1.12 GPa,respectively,which are 8.55%and 6.67%lower than those of Ti_(2)AlN/Mg,respectively.The typical delamination and kink band occurred in Ti_(2)AlN_(x) under compressive and Vickers hardness(V_(H))tests.Owing to the continuous skeleton structure and strong interfacial bonding strength,the crack ini-tiated in Ti_(2)AlN_(x) was blocked by the plastic Mg matrix.This suggests the possibility of regulating the mechanical performance of Ti_(2)AlN/Mg composites by controlling the N vacancy and the hierarchical structure of Ti_(2)AlN skeleton. | Wantong Chen Wenbo Yu Pengcheng Zhang Xufeng Pi Chaosheng Ma Guozheng Ma Lin Zhang | 2022 | International Journal of Minerals,Metallurgy and Materials2022,29,7: | 0 |
| 12 | NAD^(+)-capped RNAs are widespread in rice(Oryza sativa)and spatiotemporally modulated during development显示文摘Dear Editor,Nicotinamide adenine dinucleotide(NAD+),a nucleotidecontaining metabolite,can be incorporated as an RNA 5′cap to form NAD^(+)-capped RNAs(NAD-RNAs),which have been identified in bacteria,yeast,mammalian cells and Arabidopsis thaliana(Hu et al.,2021).Most NAD-RNAs are m RNAs encoded by the nuclear and mitochondrial genomes。 | Haijiao Dong Xufeng Wang Cong Tan Lei Gao Jie Cui Lin Liu Beixin Mo Yongzhong Xing Yu Yu Xuemei Chen | 2022 | Science China(Life Sciences)2022,65,10: | 0 |
| 13 | Hydrogel electrodes with conductive and substrate-adhesive layers for noninvasive long-term EEG acquisition显示文摘Noninvasive brain–computer interfaces (BCIs) show great potential in applications including sleep monitoring, fatigue alerts, neurofeedback training, etc. While noninvasive BCIs do not impose any procedural risk to users (as opposed to invasive BCIs), the acquisition of high-quality electroencephalograms (EEGs) in the long term has been challenging due to the limitations of current electrodes. Herein, we developed a semidry double-layer hydrogel electrode that not only records EEG signals at a resolution comparable to that of wet electrodes but is also able to withstand up to 12 h of continuous EEG acquisition. The electrode comprises dual hydrogel layers: a conductive layer that features high conductivity, low skin-contact impedance, and high robustness;and an adhesive layer that can bond to glass or plastic substrates to reduce motion artifacts in wearing conditions. Water retention in the hydrogel is stable, and the measured skin-contact impedance of the hydrogel electrode is comparable to that of wet electrodes (conductive paste) and drastically lower than that of dry electrodes (metal pin). Cytotoxicity and skin irritation tests show that the hydrogel electrode has excellent biocompatibility. Finally, the developed hydrogel electrode was evaluated in both N170 and P300 event-related potential (ERP) tests on human volunteers. The hydrogel electrode captured the expected ERP waveforms in both the N170 and P300 tests, showing similarities in the waveforms generated by wet electrodes. In contrast, dry electrodes fail to detect the triggered potential due to low signal quality. In addition, our hydrogel electrode can acquire EEG for up to 12 h and is ready for recycled use (7-day tests). Altogether, the results suggest that our semidry double-layer hydrogel electrodes are able to detect ERPs in the long term in an easy-to-use fashion, potentially opening up numerous applications in real-life scenarios for noninvasive BCI. | Hailing Xue Dongyang Wang Mingyan Jin Hanbing Gao Xuhui Wang Long Xia Dong’ang Li Kai Sun Huanan Wang Xufeng Dong Chi Zhang Fengyu Cong Jiaqi Lin | 2023 | Microsystems & Nanoengineering2023,9,3: | 0 |