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| 1 | Glutamate and aspartate alleviate testicular/epididymal oxidative stress by supporting antioxidant enzymes and immune defense systems in boars显示文摘Several potential oxidative agents have damaging effects on mammalian reproductive systems.This study was conducted to investigate the effects of glutamate(Glu)and aspartate(Asp)supplementation on antioxidant enzymes and immune defense systems in the outer scrotum of boars injected with H2O2.A total of 24 healthy boars were randomly divided into 4 treatment groups:control(basal diet,saline-treated),H2O2(basal diet,H2O2-challenged outer scrotum(1 m L kg^–1 BW)),Glu(basal diet+2%Glu,H2O2-challenged),and Asp(basal diet+2%Asp,H2O2-challenged).Our results showed that both Glu and Asp supplementation improved testicular morphology and decreased the genital index in the H2O2-treated boars.Glu and Asp administration increased the antioxidant enzyme activities and affected the testicular inflammatory cytokine secretion but had no effect on sex hormone levels.Furthermore,the m RNA expression of CAT,Cu Zn SOD,and GPx4 was altered in the testes and epididymis of boars treated with Asp and Glu.Glu and Asp supplementation also modulated the expression of TGF-β1,IL-10,TNF-α,IL-6 and IL-1βin the testis and epididymis.These results indicate that dietary Glu and Asp supplementation might enhance antioxidant capacity and regulate the secretion and expression of inflammatory cytokines to protect the testes and epididymis of boars against oxidative stress. | Wenjie Tang Jian Wu Shunshun Jin Liuqin He Qinlu Lin Feijun Luo Xingguo He Yanzhong Feng Binsheng He Pingping Bing Tiejun Li Yulong Yin | 2020 | Science China(Life Sciences)2020，63，1： | 9 |
| 2 | Rice seed storage proteins:Biosynthetic pathways and the effects of environmental factors显示文摘Rice(Oryza sativa L.)is the most important food crop for at least half of the world’s population.Due to improved living standards,the cultivation of high-quality rice for different purposes and markets has become a major goal.Rice quality is determined by the presence of many nutritional components,including seed storage proteins(SSPs),which are the second most abundant nutrient components of rice grains after starch.Rice SSP biosynthesis requires the participation of multiple organelles and is influenced by the external environment,making it challenging to understand the molecular details of SSP biosynthesis and improve rice protein quality.In this review,we highlight the current knowledge of rice SSP biosynthesis,including a detailed description of the key molecules involved in rice SSP biosynthetic processes and the major environmental factors affecting SSP biosynthesis.The effects of these factors on SSP accumulation and their contribution to rice quality are also discussed based on recent findings.This recent knowledge suggests not only new research directions for exploring rice SSP biosynthesis but also innovative strategies for breeding high-quality rice varieties. | Wei He Long Wang Qinlu Lin Feng Yu | 2021 | Journal of Integrative Plant Biology2021，63，12： | 3 |
| 3 | The RALF1-FERONIA complex interacts with and activates TOR signaling in response to low nutrients显示文摘Target of rapamycin(TOR)kinase is an evolutionarily conserved major regulator of nutrient metabolism and organismal growth in eukaryotes.In plants,nutrients are remobilized and reallocated between shoots and roots under low-nutrient conditions,and nitrogen and nitrogen-related nutrients(e.g.,amino acids)are key upstream signals leading to TOR activation in shoots under low-nutrient conditions.However,how these forms of nitrogen can be sensed to activate TOR in plants is still poorly understood.Here we report that the Arabidopsis receptor kinase FERON IA(FER)interacts with the TOR pathway to regulate nutrient(nitrogen and amino acid)signaling under low-nutrient conditions and exerts similar metabolic effects in response to nitrogen deficiency.We found that FER and its partner,RPM1-induced protein kinase(RIPK),interact with the TOR/RAPTOR complex to positively modulate TOR signaling activity.During this process,the receptor complex FER/RIPK phosphorylates the TOR complex component RAPTOR1B.The RALF1 peptide,a ligand of the FER/RIPK receptor complex,increases TOR activation in the young leaf by enhancing FER-TOR interactions,leading to promotion of true leaf growth in Arabidopsis under lownutrient conditions.Furthermore,we showed that specific amino acids(e.g.,Gin,Asp,and Gly)promote true leaf growth under nitrogen-deficient conditions via the FER-TOR axis.Collectively,our study reveals a mechanism by which the RALF1-FER pathway activates TOR in the plant adaptive response to low nutrients and suggests that plants prioritize nutritional stress response over RALF1-mediated inhibition of cell growth under low-nutrient conditions. | Limei Song Guoyun Xu Tingting Li Huina Zhou Qinlu Lin Jia Chen Long Wang Dousheng Wu Xiaoxu Li Lifeng Wang Sirui Zhu Feng Yu | 2022 | Molecular Plant2022，15，7： | 2 |
| 4 | Physicochemical properties of porous starches from different botanical origin显示文摘 | Xiao Huaxi Lin Qinlu Wu Yue | 2011 | Advanced Materials Research2011，159，： | 1 |
| 5 | Effect of microwave heating on the low-salt gel from silver carp ( Hypophthalmichthys molitrix ) surimi显示文摘 | Xiangjin Fu Khizar Hayat Zhonghai Li Qinlu Lin Shiying Xu Shuiping Wang | 2011 | Food Hydrocolloids2011，，2： | 1 |
| 6 | Production of isomalto- oligosaccharide syrup from rice starch using an one-step conversion method显示文摘 | LIN Qinlu XIAO Huaxi ZHAO Jian | 2011 | International Journal of Food Science and Technology2011，46，6： | 1 |
| 7 | Octacosanol and health benefits:Biological functions and mechanisms of action显示文摘Octacosanol is a widely distributed natural higher aliphatic alcohol that can be isolated and purified from rice bran,sugarcane,beeswax,insect wax,etc.Octacosanol exerts various biological effects,including anti-fatigue,anti-hypoxia,antioxidant,anti-inflammatory,antitumor,etc.Meanwhile,it has the effects of regulating the body's immune function and energy metabolism and has potential benefits for cardiovascular disease,cerebrovascular disorders,diabetes,Parkinson's disease,and others.Octacosanol is primarily responsible for regulating multiple signaling pathways,such as AMPK,PI3K/Akt,and MAPK/NF-κB,to achieve different physiological functions.This review systemically summarized the progress in characterization,extraction and purification,biological functions,molecular mechanisms,and bioavailability of octacosanol.This study will provide a reference for many investigators to further explore the physiological functions of higher aliphatic alcohols and apply them as supplements in functional foods. | Yaping Zhou Fuliang Cao Feijun Luo Qinlu Lin | 2022 | Food Bioscience2022，47，3： | 1 |
| 8 | Brown rice:a missing nutrient-rich health food显示文摘Brown rice(BR)is a traditional health food being rich in various active substances, which have effective preventive and therapeutic effects on many diseases. In this review, we systemically summarized the efficacy of BR on cardiovascular diseases(CVDs), hyperlipidemia, hypertension, diabetes, obesity, osteoporosis, neurodegenerative diseases, cancer, immune disorders, inflammation, anxiety, liver and stomach damage, etc. Underlying mechanisms have also been analyzed, which include regulating lipid synthesis and metabolism, improving insulin levels and increasing glucose metabolism, anti-oxidation, promoting the immune system, transcription and non-transcriptional regulation, blocking cell cycle, thereby improving disease symptoms and reducing its recurrence rate. Generally, BR has been almost disappeared in modern society, but it is promising to exploit the potential to become a functional food. Further research on the nutritional value, variety differences, storage problems, taste and molecular mechanism of BR will be conducive to help meticulously design clinical intervention trials and ultimately improve the treatment and prevention of various diseases. | Xiuxiu Wu Tianyi Guo Feijun Luo Qinlu Lin | 2023 | Food Science and Human Wellness2023，12，5： | 1 |
| 9 | Roles of FERONIA-like receptor genes in regulating grain size and quality in rice显示文摘Grain yield and quality are critical factors that determine the value of grain crops.In this study,we analyzed the functions of 12 FERONIA-like receptor(FLR)family members in rice and investigated their effects on grain size and quality.We found that FLR1,FLR2 and FLR8 negatively regulated grain size,and FLR15 positively regulated grain size.flr1 mutants had a higher cell number and an accelerated rate of grain filling compared to wild-type plants,which led to grains with greater widths.A mechanism underlying the regulation of grain size by FLR1 is that FLR1 is associated with OsRac1 Rho-like GTPase,a positive regulator of grain size.Regarding grain quality,the flr1 mutant had a higher percentage of chalkiness compared with wild-type plants,and seeds carrying mutations in flr3 and flr14 had endosperms with white floury cores.To elucidate the possible mechanism underlying this phenomenon,we found that FLR1 was constitutively expressed during endosperm development.RNA-seq analysis identified 2,367 genes that were differentially expressed in the flr1 mutant,including genes involved in starch and sucrose metabolism and carbon fixation.In this study,we identified the roles played by several FLR genes in regulating grain size and quality in rice and provided insights into the molecular mechanism governing the FLR1-mediated regulation of grain size. | Long Wang Dandan Wang Zhuhong Yang Shun Jiang Jianing Qu Wei He Zhenming Liu Junjie Xing Youchu Ma Qinlu Lin Feng Yu | 2021 | Science China(Life Sciences)2021，64，2： | 1 |
| 10 | Study on mechamism of soy protein oxidation induced by lipid per- oxidation products显示文摘 | WU Wei LIN Qinlu HUA Yufei | 2013 | Adv J Food Sci Technol2013，5，1： | 1 |
| 11 | Anticancer properties of Monascus metabolites显示文摘 | Tao Yang Junwen Liu Feijun Luo Qinlu Lin Thomas J. Rosol Xiyun Deng | 2014 | Anti-Cancer Drugs2014，，7： | 1 |
| 12 | Microwave synthesis and adsorption performance of a novel crosslinked starch microsphere显示文摘 | Qintie Lin Jianxin Pan Qinlu Lin | 2013 | J Hazard Mater2013，263，： | 1 |
| 13 | Production ofisomalto-oligosaccharide syrup from rice starch using an one-stepconversion method显示文摘 | Qinlu Lin Huaxi Xiao Jian Zhao | 2011 | International Journal of Food Science andTechnology2011，46，： | 1 |
| 14 | Rice Storage Proteins:Focus on Composition,Distribution,Genetic Improvement and Effects on Rice Quality显示文摘Rice storage proteins(RSPs)are plant proteins with high nutritional quality.As the second largest type of storage substance in rice,it is the main source of protein intake for people who consume rice as a staple food.The content and type of RSPs affect the appearance,processing quality and eating quality of rice.These effects involve the distribution of RSPs in rice grains as well as the interactions of RSPs with other components such as starch in rice grains.In the past two decades,some progress has been made in the genetic improvement of RSPs.However,the determination mechanism of protein content and composition in rice is still unclear,and the mechanism of the effect of RSPs on rice quality has not been elucidated.In this review,the composition,biosynthesis and distribution of RSPs,and quantitative trait loci mapping and cloning of RSP genes are summarized,the research progress of the influence of RSPs and their components on rice quality are reviewed,and the research directions in the future are proposed. | LONG Xinkang GUAN Chunmin WANG Lin JIA Liting FU Xiangjin LIN Qinlu HUANG Zhengyu LIU Chun | 2023 | Rice science2023，30，3： | 0 |
| 15 | Parboiled rice supplementation alleviates high-fat diet-induced hyperlipidemia by regulating genes and gut microbiota in mice显示文摘Dietary parboiled rice(PR)has a low risk of disease,but little is known about the contribution of PR to the prevention of hyperlipidemia.The potential role and underlying mechanisms of PR in hyperlipidemia were evaluated in this study.Male C57BL/6J mice were fed with a normal diet,high-fat diet(HFD)containing refined rice(HFDRR)or PR(HFDPR).It was found that PR intervention improved lipid accumulation in mice.Transcriptomic data analysis revealed that 27 genes were up-regulated(mostly involved in lipid breakdown)and 86 genes were down-regulated(mostly involved in inflammatory responses)in the HFDPR group compared to the HFDRR group.And 15 differentially expressed genes(DEGs)were validated by quantitative real-time PCR(RT-qPCR),while protein interaction network showed that protein tyrosine phosphatase receptor type C(PTPRC)has a central role.The gut microbiota of mice was also altered after different dietary treatments,with higher ratio of Firmicutes and Bacteroidetes,increased abundances of Ruminococcaceae,Lachnospiraceae,Christensenellaceae,Porphyromonadaceae,Rikenellaceae and Prevotellaceae,and decreased abundances of Lactobacillaceae,Peptostreptococcaceae,Erysipelotrichaceae and Actinobacteria in the HFDRR group.In addition,it was observed that PPAR signaling pathway may act as a bridge between DEGs and differential gut microbiota.These results suggested that PR can prevent hyperlipidemia by modulating liver genes and gut microbiota. | Xiuxiu Wu Tianyi Guo Biao Li Shuai Han Zuomin Hu Yi Luo Dandan Qin Yaping Zhou Feijun Luo Qinlu Lin | 2024 | Food Science and Human Wellness2024，13，3： | 0 |
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