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| 1 | The endoplasmic reticulum-associated degradation is necessary for plant salt tolerance显示文摘真核细胞的有机体有允许错误褶层或 unassembled 蛋白质在 endoplasmic 蜂窝胃被保留的质量控制的机制(嗯) 并且随后由嗯联系降级(ERAD ) 降级了。ERAD 小径很好在酵母和哺乳动物被学习;然而,植物 ERAD 的生物功能没被报导。通过分子、细胞的生物途径,我们发现 ERAD 是必要的让植物克服盐应力。在蛋白质在植物房间增加了的盐处理 ubiquitinated 之上,特别展开了快速在 ER 积累了并且随后导致了的蛋白质嗯压力回答。在 ERAD 小径的 HRD1/HRD3 建筑群的 HRD3A 的缺点导致了展开的蛋白质反应(UPR ) 的改变,腌的增加的植物敏感,和在植物房间的 ERAD 底层的保留。而且,我们证明从 ER 的那个 Ca 2+ 版本涉及 UPR 的举起,反应的氧种类(ROS ) 参与 ERAD 相关的植物盐反应小径。 | Lijing Liu Feng Cui Qingliang Li Bojiao Yin Huawei Zhang Baoying Lin Zaorong Wu Ran Xia Sanyuan Tang Qi Xie | 2011 | Cell Research2011，21，6： | 19 |
| 2 | The vernalization-induced long non-coding RNA VAS functions with the transcription factor TaRF2b to promote TaVRN1 expression for flowering in hexaploid wheat显示文摘Vernalization is a physiological process in which prolonged cold exposure establishes flowering competence in winter plants. In hexaploid wheat, TaVRN1 is a cold-induced key regulator that accelerates floral transition. However, the molecular mechanism underlying the gradual activation of TaVRN1 during the vernalization process remains unknown. In this study, we identified the novel transcript VAS (TaVRN1 alternative splicing) as a non-coding RNA derived from the sense strand of the TaVRN1 gene only in winter wheat, which regulates TaVRN1 transcription for flowering. VAS was induced during the early period of vernalization, and its overexpression promoted TaVRN1 expression to accelerate flowering in winter wheat. VAS physically associates with TaRF2b and facilitates docking of the TaRF2b-TaRF2a complex at the TaVRN1 promoter during the middle period of vernalization. TaRF2b recognizes the Sp1 motif within the TaVRN1 proximal promoter region, which is gradually exposed along with the disruption of a loop structure at the TaVRN1 locus during vernalization, to activate the transcription of TaVRN1. The tarf2b mutants exhibited delayed flowering, whereas transgenic wheat lines overexpressing TaRF2b showed earlier flowering. Taken together, our data reveal a distinct regulatory mechanism by which a long non-coding RNA facilitates the transcription factor targeting to regulate wheat flowering, providing novel insights into the vernalization process and a potential target for wheat genetic improvement. | Shujuan Xu Qi Dong Min Deng Dexing Lin Jun Xiao Peilei Cheng Lijing Xing Yuda Niu Caixia Gao Wenhao Zhang Yunyuan Xu Kang Chong | 2021 | Molecular Plant2021，14，9： | 7 |
| 3 | Adsorption removal of o-nitrophenol and p-nitrophenol from wastewater by metal–organic framework Cr-BDC显示文摘In the present paper, a metal–organic framework Cr-BDC was prepared and used as adsorbent for adsorption of o-nitrophenol(ONP) and p-nitrophenol(PNP) from aqueous solutions. Cr-BDC was characterized by scanning electron microscopy, transmission electron microscope, X-ray diffraction and BET methods. The results indicate that Cr-BDC gets a very large specific surface area of 4128 m^2·g^(-1)and pore sizes are concentrated in 1 nm, which is a benefit for using for wastewater treatment. The influences of the adsorption conditions, such as temperature,solution concentration, adsorption time and reusability on adsorption performance were investigated. Cr-BDC exhibited an encouraging uptake capacity of 310.0 mg·g^(-1)for ONP, and adsorption capacity of Cr-BDC for ONP is significantly higher than that for PNP under suitable adsorption conditions. The characterizations of adsorption process were examined with the Lagergren pseudo-first-order, the pseudo-second-order kinetic model, and the intra-particular diffusion model. Kinetics experiments indicated that the pseudo-second-order model displayed the best correlation with adsorption kinetics data. Furthermore, our adsorption equilibrium data could be better described by the Freundlich equation. The results indicate that the as-prepared Cr-BDC is promising for use as an effective and economical adsorbent for ONP removal. | Jianhua Chen Xue Sun Lijing Lin Xinfei Dong Yasan He | 2017 | Chinese Journal of Chemical Engineering2017，25，6： | 6 |
| 4 | An endpoint damage oriented model for life cycle environmental impact assessment of buildings in China显示文摘The midpoint impact assessment methodology and several weighting methods that are currently used by most building Life cycle assessment (LCA) researchers in China, still have some shortcomings. In order to make the evaluation results have better temporal and spatial applicability, the endpoint impact assessment methodology was adopted in this paper. Based on the endpoint damage oriented concept, four endpoints of resource exhaustion, energy exhaustion, human health damage and ecosystem damage were selected according to the situation of China and the specialties of the building industry. Subsequently the formula for calculating each endpoint, the background value for normalization and the weighting factors were defined. Following that, an endpoint damage oriented model to evaluate the life cycle environmental impact of buildings in China was established. This model can produce an integrated indicator for environmental impact, and consequently provides references for directing the sustainable building design. | GU LiJing LIN BoRong GU DaoJin ZHU YingXin | 2008 | Chinese Science Bulletin2008，53，23： | 4 |
| 5 | Oxidation behavior of ammonium in a 3-dimensional biofilm-electrode reactor显示文摘Excess nitrogenous compounds are detrimental to natural water systems and to human health. To completely realize autohy- drogenotrophic nitrogen removal, a novel 3-dimensional biofilm-electrode reactor was designed. Titanium was electroplated with ruthenium and used as the anode. Activated carbon fiber felt was used as the cathode. The reactor was separated into two chambers by a permeable membrane. The cathode chamber was filled with granular graphite and glass beads. The cathode and cathode chamber were inhabited with domesticated biofilm. In the absence of organic substances, a nitrogen removal efciency of up to 91% was achieved at DO levels of 3.42 ± 0.37 mg/L when the applied current density was only 0.02 mA/cm2. The oxidation of ammonium in biofilm- electrode reactors was also investigated. It was found that ammonium could be oxidized not only on the anode but also on particle electrodes in the cathode chamber of the biofilm-electrode reactor. Oxidation rates of ammonium and nitrogen removal efciency were found to be afected by the electric current loading on the biofilm-electrode reactor. The kinetic model of ammonium at diferent electric currents was analyzed by a first-order reaction kinetics equation. The regression analysis implied that when the current density was less than 0.02 mA/cm2, ammonium removal was positively correlated to the current density. However, when the current density was more than 0.02 mA/cm2, the electric current became a limiting factor for the oxidation rate of ammonium and nitrogen removal efciency. | Jinjing Tang Jinsong Guo Fang Fang Youpeng Chen Lijing Lei Lin Yang | 2013 | Journal of Environmental Sciences2013，25，12： | 3 |
| 6 | Mechanistic insights into the adsorption and bioactivity of fibronectin on surfaces with varying chemistries by a combination of experimental strategies and molecular simulations显示文摘Fibronectin(Fn)is significant to the performance of biomaterials,and the chemistry of biomaterial surface play important roles in Fn adsorption and subsequent cell behavior.However,the“molecular scale”mechanism is still unclear.Herein,we combined experimental strategies with molecular simulations to solve this problem.We prepared self-assembled monolayers with varying chemistries,i.e.,SAMs-CH3,SAMs-NH2,SAMs-COOH and SAMs-OH,and characterized Fn adsorption and cell behaviors on them.Next,Monte Carlo method and all-atom molecular dynamics simulations were employed to reveal the orientation/conformation of Fn on surfaces.We found that SAMs-CH3 strongly adsorbed Fn via hydrophobic interactions,but show poor bioactivity as the low exposure of RGD/PHSRN motifs and the deformation of Fn.SAMs-NH2 and SAMs-COOH could adsorb Fn efficiently via vdW interactions,electrostatic interactions,hydrogen bonds and salt bridges.Fn exhibited excellent bioactivity for cell adhesion,proliferation and osteogenic differentiation as high exposure of bioactive motifs on SAMs-NH2,or as the activation of other inferior cell-binding motifs on SAMs-COOH.SAMs-OH showed poor Fn adsorption as the water film.However,the adsorbed Fn displayed non-negligible bioactivity due to high exposure of PHSRN motif and large degree of protein flexibility.We believe that the revealed mechanism presents great potential to rationally design Fn-activating biomaterials. | Lijing Hao Tianjie Li Lin Wang Xuetao Shi Yan Fan Chang Du Yingjun Wang | 2021 | Bioactive Materials2021，6，10： | 3 |
| 7 | The Community Renewal of Shantytown Transformation in Old Industrial Cities:Evidence from Tiexi Worker Village in Shenyang,China显示文摘There are many problems,such as poverty,unemployment,poor infrastructure and how to improve the ecological environment,in the shantytowns of old industrial cities.Shantytowns are the most centralized areas with different contradictions,referred to as the‘problem areas’of urban sustainable development.The shantytown transformation of old industrial cities is a typical process of unit community disintegration,which is reflected not only in the reconstruction of physical space but also in the community renewal of social spatial integration and culture reconstruction.Based on qualitative research,questionnaires and in-depth interviews,taking Tiexi Worker Village in Shenyang as a research case,this paper attempts to analyse the characteristics and driving forces of the community renewal of shantytown transformation in old industrial cities.We found that the physical space of Tiexi Worker Village has changed considerably,which is embodied in its land use structure,living environment and community service facilities,reflecting the development of community function from simple industrial function to comprehensive functions.The residents in this community have experienced a transformation from a period of homogeneity to one of heterogeneity.The social network of the community has been destroyed.Social stratification,social differentiation and higher fluidity have occurred.Community renewal is mainly affected by macro factors such as policy regulation,economic driving,condition constraints,and micro factors such as residents’choice of living space and willingness to renew their communities.The transformation policy of the old industrial zone and the development policy of the new urban area are the fundamental and deep-seated reasons for the renewal of Tiexi Worker Village,which determine the direction of the renewal and development of the community.The paid use of land and the development of the real estate industry are the direct stimulating factors for the renewal of Tiexi Worker Village,which become the direct reasons for the spatial transformation.The changes in the population in urban and rural areas and the promotion of traffic are the driving factors for the renewal of the community,while the choice of residents and their willingness regarding community renewal are the endogenous forces for promoting community renewal.Finally,the author attempts to put forward a model of the interlaced mechanism of the forming of community renewal at the macroscopic and microcosmic levels,which are the urban renewal and reconstruction and social space differentiation of community residents,respectively. | DONG Lijing WANG Yongchao LIN Jiayi ZHU Ermeng | 2020 | Chinese Geographical Science2020，30，6： | 1 |
| 8 | miR-378-mediated glycolytic metabolism enriches the Pax7^(Hi) subpopulation of satellite cells显示文摘Adult skeletal muscle stem cells,also known satellite cells(SCs),are a highly heterogeneous population and reside between the basal lamina and the muscle fiber sarcolemma.Myofibers function as an immediate niche to support SC self-renewal and activation during muscle growth and regeneration.Herein,we demonstrate that microRNA 378(miR-378)regulates glycolytic metabolism in skeletal muscle fibers,as evidenced by analysis of myofiber-specific miR-378 transgenic mice(TG).Subsequently,we evaluate SC function and muscle regeneration using miR-378 TG mice.We demonstrate that miR-378 TG mice significantly attenuate muscle regeneration because of the delayed activation and differentiation of SCs.Furthermore,we show that the miR-378-mediated metabolic switch enriches Pax7^(Hi) SCs,accounting for impaired muscle regeneration in miR-378 TG mice.Mechanistically,our data suggest that miR-378 targets the Akt1/FoxO1 pathway,which contributes the enrichment of Pax7^(Hi) SCs in miR-378 TG mice.Together,our findings indicate that miR-378 is a target that links fiber metabolism to muscle stem cell heterogeneity and provide a genetic model to approve the metabolic niche role of myofibers in regulating muscle stem cell behavior and function. | Hu Li Lin Kang Rimao Wu Changyin Li Qianying Zhang Ran Zhong Lijing Jia Dahai Zhu Yong Zhang | 2022 | Cell Regeneration2022，11，1： | 1 |
| 9 | New loci for refractive errors and ocular biometric parameters in young Chinese Han adults显示文摘Myopia has become a major public health issue with an increasing prevalence.There are still individuals who experience similar environmental risk factors and,yet,remain non-myopic.Thus,there might be genetic factors protecting people from myopia.Considering the opposite ocular characteristics of primary angle closure glaucoma(PACG)to myopia and possible common pathway between them,we propose that certain risk genes for PACG might act as a protective factor for myopia.In this study,2,678 young adults were genotyped for 37 targeted single nucleotide polymorphisms.Compared with emmetropia,rs1401999(allele C:OR=0.795,P=0.03;genotype in dominant model:OR=0.759,P=0.02)and rs1258267(allele A:OR=0.824,P=0.03;genotype in dominant model:OR=0.603,P=0.01)were associated with low to moderate myopia and high myopia,respectively.Genotype under recessive model of rs11024102 was correlated with myopia(OR=1.456,P=0.01),low to moderate myopia(OR=1.443,P=0.02)and high myopia(OR=1.453,P=0.02).However,these associations did not survive Bonferroni correction.Moreover,rs1401999,rs1258267,and rs11024102 showed associations with certain ocular biometric parameters in different groups.Our study suggests that ABCC5,CHAT and PLEKHA7 might be associated with refractive errors by contributing to the regulation of ocular biometry,in terms of uncorrected results and their biological functions. | Yunyun Sun Zi-Bing Jin Shifei Wei Hongyan Jia Kai Cao Jianping Hu Caixia Lin Wenzai An Jiyuan Guo He LiJing Fu Shi-Ming Li Ningli Wang the Anyang University Students Eye Study Group the Anyang University Students Eye Study Group | 2022 | Science China(Life Sciences)2022，65，10： | 1 |
| 10 | Novel fiber-optic dis- tributed disturbance sensor using a modified phase generation carrier technique 显示文摘 | Lin Wentai Zhang Chunxi Li Lijing | 2011 | Advanced Materials Research2011，，： | 1 |
| 11 | Convergence and quotient convergence of iterative methods for solving singular linear e- quations with index one显示文摘 | Lin Lijing Wei Yimin Zhang Naimin | 2009 | Linear Algebra and its Applications2009，430，56： | 1 |
| 12 | Influence of degree of specific allergic sensitivity on severity of rhinitis and asthma in Chinese allergic patients显示文摘 | LiJing Huang Ymg Lin Xiaoping | 2011 | Respir Med2011，12，： | 1 |
| 13 | Effects of arginine replacement with L-citrulline on the arginine/nitric oxide metabolism in chickens:An animal model without urea cycle显示文摘Background This study examined the efficacy of L-citrulline supplementation on the arginine/nitric oxide metabolism,and intestinal functions of broilers during arginine deficiency.A total of 288 day-old Arbor Acre broilers were randomly assigned to either an arginine deficient basal diet(NC diet),NC diet+0.50%L-arginine(PC diet),or NC diet+0.50%L-citrulline(NCL diet).Production performance was recorded,and at 21 days old,chickens were euthanized for tissue collection.Results The dietary treatments did not affect the growth performance of broilers(P>0.05),although NC diet increased the plasma alanine aminotransferase,urate,and several amino acids,except arginine(P<0.05).In contrast,NCL diet elevated the arginine and ornithine concentration higher than NC diet,and it increased the plasma citrulline greater than the PC diet(P<0.05).The nitric oxide concentration in the kidney and liver tissues,along with the plasma and liver e NOS activities were promoted by NCL diet higher than PC diet(P<0.05).In the liver,the activities of arginase 1,ASS,and ASL,as well as,the gene expression of i NOS and OTC were induced by PC diet greater than NC diet(P<0.05).In the kidney,the arginase 1,ASS and ASL enzymes were also increased by PC diet significantly higher than the NC and NCL diets.Comparatively,the kidney had higher abundance of n NOS,ASS,ARG2,and OTC genes than the liver tissue(P<0.05).In addition,NCL diet upregulated(P<0.05)the m RNA expression of intestinal nutrient transporters(EAAT3 and PEPT1),tight junction proteins(Claudin 1 and Occludin),and intestinal mucosal defense(MUC2 and p Ig R).The intestinal morphology revealed that both PC and NCL diets improved(P<0.05)the ileal VH/CD ratio and the jejunal VH and VH/CD ratio compared to the NC fed broilers.Conclusion This study revealed that NCL diet supported arginine metabolism,nitric oxide synthesis,and promoted the intestinal function of broilers.Thus,L-citrulline may serve as a partial arginine replacement in broiler’s diet without detrimental impacts on the performance,arginine metabolism and gut health of chickens. | Victoria Anthony Uyanga Lijing Sun Yu Liu Meiming Zhang Jingpeng Zhao Xiaojuan Wang Hongchao Jiao Okanlawon M.Onagbesan Hai Lin | 2023 | Journal of Animal Science and Biotechnology2023，14，3： | 1 |
| 14 | Optics‑guided Robotic System for Dental Implant Surgery显示文摘At present,dental implant surgery mainly relies on the clinical experience of the doctor and the assistance of preoperative medical imaging.However,there are some problems in dental implant surgery,such as narrow space,sight obstruction,inaccurate positioning,and high requirements of doctors’proficiency.Therefore,a dental implant robot system(DIRS)guided by optical navigation is developed in this study,with an x-shaped tool and an irregular pentagonal tracer are designed for spatial registration and needle tip positioning strategy respectively.The coordinate system of each unit in DIRS is unified through system calibration,spatial registration,and needle tip positioning strategy.Then the surgical path is planned on the computed tomography(CT)images in the navigation software before operation.The automatic positioning method and the auxiliary positioning method can be used in the operation to achieve accurate positioning and assist doctors to complete the operation.The errors of spatial registration,needle tip positioning strategy,and the overall accuracy of the system were evaluated respectively,and the results showed that they all met the needs of clinical surgery.This study preliminarily verified the feasibility of the precise positioning method for dental surgery robots and provided certain ideas for subsequent related research. | Biao Yan Wenlong Zhang Lijing Cai Lingxiang Zheng Kaiyang Bao Yuming Rao Lin Yang Weitao Ye Peifeng Guan Wei Yang Jiang Li Rongqian Yang | 2022 | Chinese Journal of Mechanical Engineering2022，35，3： | 1 |
| 15 | Thermal degradation behavior and gas phase flame‐retardant mechanism of polylactide/PCPP blends显示文摘 | Haijuan Lin Lijing Han Lisong Dong | 2014 | J Appl Polym Sci2014，，13： | 1 |
| 16 | Ultrasmall Ru nanoparticles supported on chitin nanofibers for hydrogen production from NaBH4 hydrolysis显示文摘In this work,a series of chitin-supported Ru catalysts,composed of ultrasmall Ru nanoparticles supported on the chitin nanofibers,with different Ru content from 0.07 wt%to 0.93 wt%,are fabricated.Results from catalyzed NaBH4 hydrolysis experiments indicate that the catalytic activity of the fabricated chitin-supported Ru catalysts increases gradually with the decreasing of Ru content.The rate of hydrogen generation from NaBH4 hydrolysis catalyzed by the catalyst with 0.07 wt%Ru content is as high as 55.29 L min 1 gRu-1 at 30℃,and this reaction exhibits activation energy of 39.16 kJ/mol.The augment of NaBH4 dosage in the experiments does not weaken the catalytic activity.In addition,the fabricated chitin-supported Ru catalysts show excellent durability in NaBH4 hydrolysis,with only 9.2%activity loss after used for 20 cycles.With excellent catalytic activity and durability,the as-obtained Ru catalysts provide a promising choice for promoting hydrogen production from NaBH4 hydrolysis. | Jiapeng Zhang Fanzhen Lin Lijing Yang Zhaoyi He Xiaoshan Huang Dingwei Zhang Hua Dong | 2020 | Chinese Chemical Letters2020，31，7： | 0 |
| 17 | Correction to: miR-378-mediated glycolytic metabolism enriches the Pax7Hi subpopulation of satellite cells显示文摘Following publication of the original article(Li et al.,2022),due to a typesetting error,the sentence below was missing in the article.Hu Li and Lin Kang contributed equally to this work.The correct information has been provided in this Correction and the original article(Li et al.,2022)has been updated. | Hu Li Lin Kang Rimao Wu Changyin Li Qianying Zhang Ran Zhong Lijing Jia Dahai Zhu Yong Zhang | 2022 | Cell Regeneration2022，11，1： | 0 |
| 18 | Highly dispersed Ru/Co catalyst with enhanced activity for catalyzing NaBH4 hydrolysis in alkaline solutions显示文摘Ru and Co are highly dispersed on the surface of TiO2 nanopa rticles with an easy coprecipitation method to fabricate a novel Ru-based catalyst(Ru/Co-TiO2).The fabricated Ru/Co-TiO2 catalyst exhibits superior catalytic performance for promoting NaBH4 hydrolysis in alkaline medium,showing an impressive hydrogen generation rate per gram Ru as high as 172 L min-1 gRu-1 which is better than most of recently reported Ru-based catalysts.In addition,the fabricated Ru/Co-TiO2 catalyst also shows excellent du rability in cycle use,with only 2.9% activity loss after being used for 5 cycles.These advantages make the developed Ru/Co-TiO2 catalyst a potential choice for promoting hydrogen generation from NaBH4 hydrolysis. | Jiapeng Zhang Fanzhen Lin Lijing Yang Hua Dong | 2020 | Chinese Chemical Letters2020，31，9： | 0 |
| 19 | Cell-penetrating riboflavin conjugate for antitumor photodynamic therapy显示文摘Riboflavin(RF,vitamin B2)is an essential vitamin and has been considered as a promising natural photosensitizer for photodynamic therapy(PDT).However,further exploration of RF in antitumor application was limited by its poor cellular uptake.In this study,using cell-penetrating peptides Arg8,(Cha-Arg)3 and small molecule triphenylphosphine(TPP)as delivery compounds,three RF conjugates were prepared to increase the accumulation of RF in cells,termed as Arg8-RF,(Cha-Arg)3-RF and TPP-RF,respectively.Compared with TPP-RF and Arg8-RF,(Cha-Arg)3-RF exhibited better cell internalization and stronger cytotoxicity against HeLa cells upon exposure to blue light.Further researches proved that(Cha-Arg)3-RF generated reactive oxygen species(ROS)under irradiation,which could indiscriminately destroy endogenous proteins and mitochondria,ultimately inducing cell death.This work provides a new approach to explore RF as a natural photosensitizer for antitumor photodynamic therapy. | Chunlei Wu Yanyan Li Zhehong Cheng Pengxin Wang Zhilong Ma Ke Liu Yulian Cheng Yimin Zhou Xian Lin Ximing Shao Yong Yang Hongchang Li Lijing Fang | 2022 | Chinese Chemical Letters2022，33，9： | 0 |
| 20 | Iron-doped Ag/Ni_(2)(CO_(3))(OH)_(2)hierarchical microtubes for highly efficient water oxidation显示文摘Doping of foreign atoms and construction of unique structures are considered as effective approaches to design high-activity and strongdurability electrocatalysts.Herein,we report Fe-doped nickel hydroxide carbonate hierarchical microtubes with Ag nanoparticles(denoted Ag/NiFeHC HMTs)through hydrolysis precipitation process.Experimental tests and density functional theory calculations reveal that Fe doping can tune the electron configuration to enhance the conductivity,markedly improve the electrochemical surface area to expose more active sites,and act as reactive centers to lower the free energy of the rate determination step.In addition,the unique hierarchical structure can also offer active sites and excellent cycling stability.Benefitting from these advantages,the as-obtained Ag/NiFeHC HMTs show excellent oxygen evolution reaction activity,with an overpotential of 208 mV at 10 mA cm^(−2)in 1.0M KOH.Also,it could achieve long-term stability at a current density of 20 mA cm^(−2)for 24 h. | Huiwen Zhang Shuxuan Liu Enlai Hu Yunfei Yang Huimin Zhang Yuting Zhu Lijing Yan Xuehui Gao Jing Zhang Zhan Lin | 2022 | Carbon Energy2022，4，5： | 0 |
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