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| 1 | A combined computational pipeline to detect circular RNAs in human cancer cells under hypoxic stress显示文摘Hypoxia is associated with several diseases,including cancer.Cells that are deprived of adequate oxygen supply trigger tran-scriptional and post-transcriptional responses,which control cellular pathways such as angiogenesis,proliferation,and metabolic adaptation.Circular RNAs(circRNAs)are a novel class of mainly non-coding RNAs,which have been implicated in multiple cancers and attract increasing attention as potential biomarkers.Here,we characterize the circRNA signatures of three different cancer cell lines from cervical(HeLa),breast(MCF-7),and lung(A549)cancer under hypoxia.In order to reliably detect circRNAs,we integrate available tools with custom approaches for quantification and statistical analysis?Using this consolidated computational pipeline,we identify?12000 circRNAs in the three cancer celUines.Their molecular characteristics point to an involvement of complementary RNA sequences as well as trans-acting factors in circRNA biogenesis,such as the RNA-binding protein HNRNPC-Notably,we detect a number of circRNAs that are more abundant than their linear counterparts.In addition,64 circRNAs significantly change in abundance upon hypoxia,in most cases in a cell type-specific manner.In summary,we present a comparative circRNA profiling in human cancer cell lines,which promises novel insights into the biogenesis and function of circRNAs under hypoxic stress. | Antonella Di Liddo Camila de Oliveira Freitas Machado Sandra Fischer Stefanie Ebersberger Andreas WHeumliller Julia EWeigand Michaela Muller-McNicoll Kathi Zarnack | 2019 | Journal of Molecular Cell Biology2019，11，10： | 3 |
| 2 | Hepatic Artery Ligation for Arterial Rupture Following Liver Transplantation: A Reasonable Option显示文摘 | E. Boleslawski A. F. Bouras S. Truant G. Liddo A. Herrero B. Badic M. Audet M. Altieri A. Laurent N. Declerck F. Navarro C. Létoublon P. Wolf L. Chiche D. Cherqui F. R. Pruvot | 2013 | American Journal of Transplantation2013，，4： | 2 |
| 3 | Ratiometric detection of Cr3+and Hg2+by a naphthalimide-rhodamine based fluorescent probe显示文摘 | Mahato P Saha S Suresh E Liddo R D Parnigotto P P Conconi M T Kesharwani M K Ganguly B Das A | 2012 | Inorganic Chemistry2012，51，： | 1 |
| 4 | New immortalized human stromal cell lines enhancing in vitro expansion of cord blood hematopoietic stem cells显示文摘 | De Angeli S Di Liddo R Buoro S | 2004 | Int J Mol Med2004，13，3： | 1 |
| 5 | Pelvic recurrence of rectal cancer:our experience显示文摘 | Di Bartolomeo N Balestra M R Liddo G | 2005 | Suppl Tumori2005，4，3： | 1 |
| 6 | Pelvic recurrence of rectal cancer: our experience 显示文摘 | Di Bartolomeo N Balestra MR Liddo G | 2005 | Suppl Tumori2005，4，： | 1 |
| 7 | Massive bone allograft reconstruction in high-grade osteosarcoma显示文摘 | Donati D Di Liddo M Zavatta M | | 0，，： | 1 |
| 8 | Tracheal matrices,obtained by a detergent-enzymatic method,support in vitro the adhesion of chondrocytes and tracheal epithelial calls显示文摘 | Conconi MT De Coppi P Di Liddo R | 2005 | Transpl Int2005，18，6： | 1 |
| 9 | CD105 ( + ) cells from Wharton's jelly show in vitro and in vivo myogenic differentiative potential显示文摘 | Conconi MT Burra P Di Liddo R | 2006 | Int J Mol Med2006，18，： | 1 |
| 10 | Massive bone allograft reconstruction in High-Grade osteosarcoma显示文摘 | Donati Davide Di Liddo Michele Zavatta Marcello | 2000 | Clin Orthop2000，，377： | 1 |
| 11 | Massive bone allograft reconstruction in high - grade osteosarcoma 显示文摘 | DONATI D DI LIDDO M ZAVATTA M | 2000 | Clin Orthop2000，377，： | 1 |
| 12 | CD105+cells from Wharton's jelly show in vitro myogenic differentiative potential显示文摘 | Concni MT Burra P Di Liddo R | 2006 | Int J Mol Med2006，18，： | 1 |
| 13 | Tracheal matrices, obtained by a deter-gent-enzymatic method,support in vitrothe adhesion of chondrocytes and trachealepithelial cells 显示文摘 | Conconi MT De Coppi P Di Liddo R etal | 2005 | Transpl Int2005，18，6： | 1 |
| 14 | Massive bone allograft reconstruction in high-grade osteosarcoma显示文摘 | Donati D Di Liddo M Zavatta M | 2000 | Clin Orthop2000，377，： | 1 |
| 15 | CD105(+) cel s from Wharton's jel y show in vitro and in vivo myogenic differentiative potential显示文摘 | Conconi MT Burra P Di Liddo R | | 0，，06： | 1 |
| 16 | A Cross-sectional Study of Homocysteine-, NO-levels, and CT-findings in Alzheimer Dementia, Vascular Dementia and Controls显示文摘 | Marcella Folin Silvia Baiguera Maurizio Gallucci Maria Teresa Conconi Rosa Liddo Andrea Zanardo Pier Paolo Parnigotto | 2005 | Biogerontology2005，，4： | 1 |
| 17 | CD105 ( + ) cells from Wharton's jelly show in vitro and in vivo myoge- nic differentiative potential 显示文摘 | Conconi MT Burra P Di Liddo R | 2006 | Int J Mol Med2006，18，6： | 1 |
| 18 | Massive boneallograft reconstruction in high-grade osteosacoma 显示文摘 | Donati D Di Liddo M Zavatta M | 2000 | Clin Orthop2000，，377： | 1 |
| 19 | Laparoscopic approach to acuteabdomen:a single-center clinical experience显示文摘 | Napolitano L Waku M Liddo G | 2008 | G Chir2008，29，12： | 1 |
| 20 | Apolipoprotein E as vascular risk factor in neurodegenerative dementia.显示文摘 | Marcella Folin Silvia Baiguera Maria Teresa Conconi Rosa Di Liddo Eugenio De Carlo Pier Paolo Parnigotto Gastone G Nussdorfer | 2004 | International Journal of Molecular Medicine2004，，4： | 1 |
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