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| 1 | Efficacy and safety of endoscopic prophylactic treatment with undiluted cyanoacrylate for gastric varices显示文摘AIM:To evaluate the efficacy and safety of undiluted N-butyl-2 cyanoacrylate plus methacryloxysulfolane(NBCM)as a prophylactic treatment for gastric varices(GV)bleeding.METHODS:This prospective study was conducted at a single tertiary-care teaching hospital between October 2009 and March 2013.Patients with portal hypertension(PH)and GV,with no active gastrointestinal bleeding,were enrolled in primary prophylactic treatment with NBCM injection without lipiodol dilution.Initial diagnosis of GV was based on endoscopy and confirmed with endosonography(EUS); the same procedure was used after treatment to confirm eradication of GV.After puncturing the GV with a regular injection needle,1 mL of undiluted NBCM was injected intranasally into GV.The injection was repeated as necessary to achieve eradication or until a maximum total volume of 3 mL of NBCM had been injected.Patients were followed clinically and evaluated with endoscopy at 3,6 and 12 mo.Later follow-ups were performed yearly.The main outcome measures were efficacy(GV eradication),safety(adverse events related to cyanoacrylate injection),recurrence,bleeding from GV and mortality related to GV treatment.RESULTS:A total of 20 patients(15 male)with PH and GV were enrolled in the study and treated with undiluted NBCM injection.Only 2(10%)patients had no esophageal varices(EV); 18(90%)patients were treated with endoscopic band ligation to eradicate EV before inclusion in the study.The patients were followed clinically and endoscopically for a median of 31 mo(range:6-40 mo).Eradication of GV was observed in all patients(13 patients were treated with 1 session and 7 patients with 2 sessions),with a maximum injected volume of 2 mL NBCM.One patient had GV recurrence,confirmed by EUS,at 6-mo follow-up,and another had late recurrence with GV bleeding after 35 mo of follow-up; overall,GV recurrence was observed in 2 patients(10%),after 6 and 35 mo of follow-up,and GV bleeding rate was 5%(1 patient).Mild epigastric pain was reported by 3 patients(15%).No mortality or major complications,including embolism,or damage to equipment were observed.CONCLUSION:Endoscopic injection with NBCM,without lipiodol,may be a safe and effective treatment for primary prophylaxis of gastric variceal bleeding. | Matheus Cavalcante Franco Gustavo Flores Gomes Frank Shigeo Nakao Gustavo Andrade de Paulo Angelo Paulo Ferrari Jr Ermelindo Della Libera Jr | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，6： | 16 |
| 2 | Chronic radiation proctopathy: A practical review of endoscopic treatment显示文摘Chronic radiation proctopathy(CRP) is a troublesome complication of pelvic radiotherapy. The most common presentation is rectal bleeding. CRP symptoms interfere with daily activities and decrease quality of life. Rectal bleeding management in patients with CRP represents a conundrum for practitioners. Medical therapy is ineffective in general and surgical approach has a high morbidmortality. Endoscopy has a role in the diagnosis,staging and treatment of this disease. Currently available endoscopic modalities are formalin,potassium titanyl phosphate laser,neodymium:yttrium-aluminum-garnet laser,argon laser,bipolar electrocoagulation(BiCAP),heater probe,band ligation,cryotherapy,radiofrequency ablation and argon plasma coagulation(APC). Among these options,APC is the most promising. | Luciano Lenz Rachel Rohr Frank Nakao Ermelindo Libera Angelo Ferrari | 2016 | World Journal of Gastrointestinal Surgery2016，8，2： | 7 |
| 3 | A signature of immune function genes associated with recurrence-free survival in breast cancer patients显示文摘 | Maria Libera Ascierto Maciej Kmieciak Michael O. Idowu Rose Manjili Yingdong Zhao Margaret Grimes Catherine Dumur Ena Wang Viswanathan Ramakrishnan Xiang-Yang Wang Harry D. Bear Francesco M. Marincola Masoud H. Manjili | 2012 | Breast Cancer Research and Treatment2012，，3： | 2 |
| 4 | Fracture resistance of teethrestored with two different post-and-core designs cemented with two different cements:An in vitro study PartI显示文摘 | Mezzomo E Massa F Libera SD | 2003 | Quintessence Int2003，34，3： | 1 |
| 5 | Disc chondrocyte transplantation in a canine model:a treatment for degenerated or damaged intervenebral disc显示文摘 | Ganey T Libera J Moos V | 2003 | Spine2003，28，23： | 1 |
| 6 | Some classes of regular univalent functions显示文摘 | Libera R J | 1965 | Proc Amer Math Soc1965，16，： | 1 |
| 7 | Surface loss in ozone-based atomic layer depositionprocesses 显示文摘 | KNOOPS H C M ELAM J W LIBERA J A | 2011 | Chemistry of Materials2011，23，23： | 1 |
| 8 | Effects of implantation temperature on the structure, composition, and oxidation resistance of aluminum-implanted SiC显示文摘 | YANG Zunde DU Honghua LIBERA Matthew | 1995 | J Mater Res1995，10，6： | 1 |
| 9 | Beneficial effects on skeletal muscle of the an giotensin Ⅱ type Ⅰ receptor blocker irbesartan in experimental heart failure 显示文摘 | Dalla Libera L Ravara B Angelini A | 2001 | Circulation2001，103，： | 1 |
| 10 | Alteration of oxidation behavior of silicon carbide by aluminum implantation显示文摘 | DU H YANG Z LIBERA M | 1995 | J Mater Sci Lett1995，14，： | 1 |
| 11 | Apoptosis and atrophy in rat slow skeletal muscles in chronic heart failure 显示文摘 | Libera LD Zennaro R Sandri M | 1999 | Am J Physiol1999，277，51： | 1 |
| 12 | Chemistry and structure of beta silicon carbide implanted with high-dose aluminum 显示文摘 | DU Honghua YANG Zunde LIBERA Matthew | 1993 | J Am Ceram Soc1993，76，2： | 1 |
| 13 | Morphological Development in Solvent - Cast Polystyrene - Polybutadiene - Polystyrene (SBS) 显示文摘 | Kim G Libera M | 1998 | Macromolecules1998，31，8： | 1 |
| 14 | Human bocavirus in children with acute gastroenteritis in Albania显示文摘 | G. La Rosa S. Della Libera M. Iaconelli D. Donia F. Cenko G. Xhelilaj P. Cozza M. Divizia | 2016 | J. Med. Virol2016，，： | 1 |
| 15 | Viral infections acquired indoors through airborne, droplet or contact transmission显示文摘 | La Rosa G Fratini M Della Libera S | 2013 | Ann Ist Super Sanita2013，49，2： | 1 |
| 16 | Disc chondrocyte transplantation in a canine model:a treatment for degenerated or damaged intervertebral disc显示文摘 | Ganey T Libera J Moos V | 2003 | Spine2003，28，23： | 1 |
| 17 | Apop tosis and atrophy in rat slow skeletalmuscles in chronic heart failure 显示文摘 | Libera LD Zennaro R SandriM | 2006 | Am J Physiol2006，277，521： | 1 |
| 18 | Papillary thyroid carcinoma of the thyroglossal duct cyst : comparative cytohistologic and immunochemical study of 2 new cases and review of the literature 显示文摘 | Falconieri G Della Libera D Zanella M | 2001 | Int J Surg Pathol2001，9，1： | 1 |
| 19 | Conformal ZnO coatings on high sttrface area silica gel using atomic layer deposition 显示文摘 | LIBERA J A ELAM J W PELLIN M J | 2008 | Thin Solid Films2008，516，18： | 1 |
| 20 | Endosonographyguided drainage of pancreatic pseudocyst without gastric or duodenal compression显示文摘 | Ardengh JC Della Libera E Ferrari AP | 1998 | Endoscopy1998，30，： | 1 |
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