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| 1 | Analysis of the composition of the bacterial community in puffer fish Takifugu obscurus显示文摘 | Yang GM Bao BL Peatman E Li HR Huang LB Ren DM | 2007 | 中国生物学文摘2007，21，8： | 19 |
| 2 | Identification of tumor associated single-chain Fv by panning and screening antibody phage library using tumor cells显示文摘AIM:To study the feasibility of panning and screeningphage-displaying recombinant single-chain variablefragment (ScFv) of anti-tumor monoclonal antibodiesfor fixed whole cells as the carriers of mAb-bindingantigens.ME,ODS: The recombinant phage displaying librariesfor anti-colorectal tumor mAb MC3Ab, MC5Ab andanti-gastric tumor mAb MGD1 was constructed.Panning and screening were carried outby means ofmodified fixation of colorectal and gastric tumor cellsexpressed the mAb-binding antigens. Concordance ofbinding specificity to tumor cells between phageclones and parent antibodies was analyzed. Thephage of positive clones was identified withcompetitive ELISA, and infected by E.coli HB2151 toexpress soluble ScFv.RESULTS:The ratio of positive clones to MC3-ScF-MC5-ScFv and MGD1-ScFv were 60 %, 24 % and 30 %. MC3-ScFv had Mr 32 000 confirmed by Western blot. Thespecificity to antigen had no difference between 4positive recombinant phage antibodies and MC3Ab.CONCLUSION:The modified process of fixing wholetumor cells is efficient, convenient and feasible to panand screen the phage-displaying ScFv of anti-tumormonoclonal antibodies. | Nie, YZ He, FT Li, ZK Wu, KC Cao, YX Chen, BJ Fan, DM | 2002 | World Journal of Gastroenterology2002，8，4： | 12 |
| 3 | Anatomic structural study of cerebellopontine angle via endoscope显示文摘在颅骨底依靠寻找内视镜的技术的可能的解剖基础的背景最低限度地侵略的外科是争论的。这研究的目的是在 cerebellopontine 角度区域观察在主要的血容器和神经之间的空间关系并且为侧面、以后的颅骨底提供解剖基础经由内视镜的 retrosigmoid 锁眼 approach.Methods 的最低限度地侵略的外科这研究在三十个弄干的成年颅骨上被进行测量空间关系在之中出现以后的头部的窝的多骨的标记,并且为 retrosigmoid 锁眼 ap 定位最适当的钻区域在直径与 2.0 厘米在这个点上集中的一个洞对在 cerebellopontine 角度暴露相关结构合适。 Retrosigmoid 锁眼途径罐头减少小脑上的压力并且有效地暴露相关结构它包括面部神经, vestibulocochlear 神经,三叉的神经,舌与喉的神经,迷走神经神经,附件神经,舌下神经神经,前面的劣等的小脑的动脉,以后的劣等的小脑的动脉和迷宫的动脉,内诊镜 retrosigmoid 途径上的准确地点能避免在最低限度地侵略的外科期间拖小脑的 etc.Conclusions 。retrosigmoid 锁眼途径的申请将扩大内视镜的技术的申请。 | XIA Yin LI Xi-ping HAN De-min ZHENG Jun LONG Hai-shan SHI Jin-feng Department of Otolaryngology,Beijing Tongren Hospital,Capital Medical University Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University),Ministry of Education,Beijing 100730,China (Xia Y,Li XP,Han DM,Zheng J,Long HS and Shi JF) | 2007 | Chinese Medical Journal2007，，20： | 7 |
| 4 | High-dose methylprednisolone can induce remissions in patients with fludarabine- refractory chronic lymphocytic leukaemia显示文摘 | Xu, W Miao, KR Hong, M Zhu, DX Fang, C Dong, HJ Wang, DM Cao, X Li, JY | 2010 | 南京医科大学学报(自然科学版)2010，30，11： | 5 |
| 5 | 钢板的二次加工脆化显示文摘为满足对冷成形性能的更高要求,开发出无间隙原子(IF)钢,IF钢之所以具有优良的深冲性能,除了因为添加用于稳定间隙元素的钛和铌微合金之外,还因为钢中的碳和氮含量极低。 | Li,DM 李振贺 | 2000 | 世界钢铁2000，，2： | 2 |
| 6 | Role of Tissue Plasminogen Activator Receptor LRP in Hippocampal Long - Term Potentiation 显示文摘 | Zhuo M Holtzman DM Li Y | 2000 | The Journal of Neuroscience2000，20，2： | 1 |
| 7 | TEPI,encoded by a candidate tumor suppressor locus,is a novel protein tyrosinc phosphatase regulated by transforming growth factor β显示文摘 | Li DM Sun H | 1997 | Cancer Res1997，57，11： | 1 |
| 8 | Clinical value of com- bined detection of serum tumor markers in lung cancer diag- nosis 显示文摘 | Chen F Li WM Wang DM | 2008 | Sichuan Da Xue Xue Bao Yi Xue Ban2008，39，5： | 1 |
| 9 | Extended perceptual leaxning results in substantial recovery of positional acuity and visual acuity in juvenile amblyopia 显示文摘 | Li RW Provost A Levi DM | 2007 | Invest Ophthalmol Vis Sci2007，48，11： | 1 |
| 10 | TEP1,encoded by a candidate tumor suppressor locus,is a novel protein tyrosine phosphatase regulated by transforming growth factor β显示文摘 | Li DM Sun H | 1997 | Cancer Bes1997，57，： | 1 |
| 11 | Signaling mechanism of cell adhesion molecules in breast cancer metastasis: potential therapeutic targets显示文摘 | Li DM Feng YM | 2011 | Breast Cancer Res Treat2011，128，1： | 1 |
| 12 | Risk of iodine excess in school children in Guizhou province , china 显示文摘 | Li XS Zhou DM Yao ZY | 2010 | IDD Newsletter2010，38，4： | 1 |
| 13 | Hepatoprotective sesquiterpeneglycosides from Sarcandra glabra 显示文摘 | Li Y Zhang DM Li JB | 2006 | J Nat Prod2006，69，： | 1 |
| 14 | Cerebral phaeohyphomycosis-a cure at what lengths? 显示文摘 | Li DM de Hoog GS | 2009 | The Lancet Infectious Diseases2009，9，6： | 1 |
| 15 | eBURST : inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data显示文摘 | Feil EJ Li BC Aanensen DM | 2004 | J Bacteriol2004，186，5： | 1 |
| 16 | (Pro)renin Receptor mediates both angiotensinⅡdependent and-independent oxidative stress in neuronal cells显示文摘 | Peng H Li W Seth DM | 2013 | PLo S One2013，8，58： | 1 |
| 17 | Estimation and projection of therational profile of cancer mortality in China:1991-2005显示文摘 | Yang L Parkin DM LI LD et a1 | 2008 | Br JCancer2008，90，11： | 1 |
| 18 | Signaling mechanism of cell adhesion moleculesin breast cancer metastasis: potential therapeutic targets显示文摘 | Li DM Feng YM | 2011 | Breast Cancer Res Treat2011，128，1： | 1 |
| 19 | Improving the performance of the amblyopic visual system 显示文摘 | Levi DM Li RW | 2009 | Philos Trans R Soc Lond B Biol Sci2009，364，1515： | 1 |
| 20 | Protein expression and pro- moter methylation of the candidate biomarker TCF21 in gastric cancer显示文摘 | YANG Z LI DM XIE Q | 2015 | J Cancer Res Clin Oncol2015，141，2： | 1 |
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