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    题名 作者 年代 出处 被引量
1Treatment of esophageal carcinoma 显示文摘Lerut T Coosemans W De Leyn P 1999Chest1999,116,6:7
2Treatment of esophageal carcinoma显示文摘Lerut T Coosemans W De Leyn P 1999Chest (Supplement)1999,116,6:2
3Molecular epidemiology of Giardia duodenalis infection in humans in Southern Ethiopia:a triosephosphate isomerase gene-targeted analysis显示文摘Background:Giardia duodenalis is a species complex consisting of multiple genetically distinct assemblages.The species imposes a major public health crisis on developing countries.However,the molecular diversity,transmission dynamics and risk factors of the species in these countries are indeterminate.This study was conducted to determine the molecular epidemiology of G.duodenalis infection in asymptomatic individuals in Southern Ethiopia.Methods:From March to June 2014,fresh stool samples were collected from 590 randomly selected individuals.Socio-demographic data were gathered using a pre-tested structured questionnaire.The genotyping was done using triosephosphate isomerase gene-based nested polymerase chain reaction and DNA sequencing.The genetic identity and relatedness of isolates were determined using the basic local alignment search tool and phylogenetic analysis.Risk factors associated with G.duodenalis infection were analysed using binary and multinomial logistic regression models.Results:The results showed that 18.1%(92/509)of the study subjects were infected by G.duodenalis.Among the isolates,35.9%(33/92)and 21.7%(20/92)were sub-typed into assemblages A and B,respectively,whereas 42.4%(39/92)showed mixed infections of A and B.Most of the assemblage A isolates(94%,31/33)were 100%identical to sequences registered in GenBank,of which the majority belonged to sub-assemblage AII.However,the high genetic variability and frequency of double peaks made sub-genotyping of assemblage B more problematic and only 20%(4/20)of the isolates matched 100%with the sequences.The risk factors of age(P=0.032)and type of drinking water source(P=0.003)both showed a significant association with the occurrence G.duodenalis infection.Conclusions:This study established the endemicity of G.duodenalis in Southern Ethiopia.Infection with assemblage A was more frequent than with assemblage B,and the rate of infection was higher in children and in municipal/tap and open spring water consumers than the other groups.Sub-typing of assemblage B and determining the origin of double peaks were challenging.The present study confirms the need for further inclusive studies to be conducted focusing on sub-types of assemblage B and the origin of heterogeneity.Mengistu Damitie Zeleke Mekonnen Tadesse Getahun Dante Santiago Luc Leyns 2018Infectious Diseases of Poverty2018,7,1:2
4Long-term survival of surgically staged IIIA-N2 non-small-cell lung cancer treated with surgical combined modality approach: analysis of a 7-year prospective experience显示文摘Lorent N De Leyn P Lievens Y 2004Ann Oncol2004,15,11:1
5Tracheotomy:elinieal review and guidelines显示文摘De Leyn P Bedert L Delcroix M 2007Eur J Cardiothorac Surg2007,32,3:1
6Lymph node staging in non-small cell lung cancer with FDG-PET scan: a prospective study on 690 lymph node stations from 68 patients 显示文摘Vansteenkiste JF Stroobants SG De Leyn PR 1998J Clin Oncol1998,16,:1
7Infections in systemic lupus erythematosus显示文摘Navarra SV Leynes MS 2010Lupus2010,19,12:1
8Rescue of a human mRNA splicing defect by the plant cytokinin kinetin显示文摘Slaugenhaupt S A Mull J Leyne M Cuajungco M P Gill S P Hims M M Quintero F Axelrod 0,,04:1
9Tracheotomy: clinical review and guidelines显示文摘De Leyn P Bedert L Delcroix M 2007Eur J Cardiothorac Surg2007,32,3:1
10Relation between endoscopic ultrasound findings and outcome of patients with tumors of the esophagus or esophagogastric junction显示文摘Martin Hiele Paul De Leyn Piet Schurmans Antoon Lerut Steven Huys Karel Geboes Anne-Marie Gevers Paul Rutgeerts 1997Gastrointestinal Endoscopy1997,,5:1
11ESTS guidelines for intraoperative lymph node staging in non-small cell lung cancer显示文摘Lardinois D De Leyn P Van Schil P 2006Eur J CardiothoracSurg2006,30,5:1
12Tumors of the esophagogastric junction:long-term survival in relation to the pattern of lymph node metastasis and a critical analysis of the accuracy or inaccuracy of TNM classification 显示文摘Steup WH Leyn PD Denffe G 1996J Thorac cardiovasc Surg1996,111,1:1
13Cervical videomediastinoscopy显示文摘Lerut T De Leyn P Coosemans W 2010Thorac Surg Clin2010,20,:1
14Prospective comparative study of integrated positron emission tomography-computed tomography scan compared with remediastinoscopy in the assessment of residual mediastinal lymph node disease after induction chemotherapy for mediastinoscopy-proven stage IIIA-N2 non-small-cell lung cancer:, a Leuven Lung Cancer Group Study 显示文摘De Leyn P Stroobants S De Wever W 2006J Clin Oneol2006,24,21:1
15Tracheostomy: clinical review and guidelines显示文摘De Leyn P Bedert L Delcroix M 2007Eur J Cardiothorc Surg2007,32,3:1
16Stand- ardization of real-time PCR gene expression data from independent biological replicates 显示文摘WILLEMS E LEYNS L VANDESOMPELI J 2008Analytical Bio- chemistry2008,379,1:1
17Tracheotomy: clinical review and guidelines 显示文摘De Leyn P Bedert L Delcroix M 2007Eur J Cardiothorac Surg2007,32,3:1
18Minimally invasive esophagectomy for cancer 显示文摘Decker G Coosemans W De Leyn P 2009Eur J Cardiothorac Surg2009,35,1:1
19Treatment of esophageal carcinoma显示文摘Lerut T Coosemans W De Leyn P 1999Chest1999,116,6:1
20Tracheotomy: clinical review and guidelines 显示文摘De Leyn P Bedert L Deleroix M et ai 2007European Journal of Cardio-Thoracic Surgery2007,32,3:1
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