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| 1 | Transcranial direct current stimulation in psychiatric disorders显示文摘The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry. | Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni | 2015 | World Journal of Psychiatry2015，5，1： | 6 |
| 2 | Molecular markers(PECAM-1,ICAM-3,HLA-DR)determine prognosis in primary non-Hodgkin's gastric lymphoma patients显示文摘瞄准:与主要 non-Hodgkin 的胃的淋巴瘤在病人调查 PECAM-1, ICAM-3 和 HLA 医生抗原的预示的意义。方法:我们免疫组织化学地在 36 个 B 房间麦芽类型主要胃的淋巴瘤病人学习了 PECAM-1, ICAM-3 和 HLA 医生抗原表示。十非恶意并且十个健康胃的织物标本被用作控制。Clinicopathological 和幸存数据与染色的结果被相关。结果:HLA 医生抗原表示在 33 个胃的淋巴瘤病人(91.7%) 和 6 个非恶意的病人(54.5%) 被检测。PECAM-1 染色了 10 个病人(27.8%) 的肿瘤房间, 9 个病人(25%) 的 endothelial 并且煽动性有良性的胃的疾病的 4 个病人(40%) 渗入。ICAM-3 表示在 17 个病人(47.2%) 的肿瘤房间上被观察,当 5 个非恶意的病人(50%) 被染色时积极也。任何一个都没为任何学习的基因健康控制被染色。在里面多,变量分析, HLA 医生抗原和 PECAM-1 被证明是与联系的统计上重要的独立预示的因素一赞成并且不利预后分别地(P=0.009 和 P=0.003 ) 。在 univariate 分析, PECAM-1 (+)/ICAM-3 (-) 和 HLA 医生(-)/ICAM-3 (-) 病人与确切相反的基因表示模式与那些相比展出了显著地减少的全面幸存(P=0.0041 和 P=0.0091,分别地) 。是 HLA 医生(+)/ICAM-3 (+)/PECAM-1 (-)(n=8 ) 的那些病人让显著地更高的幸存与这个组(n=24 )(P=0.0289 ) 的其余部分相比评价。结论:PECAM-1, ICAM-3 和 HLA 医生分别地是肿瘤扩大潜力和主人免疫者监视的代表性的标记。他们的联合使用可以帮助我们识别能得益于更好攻击的治疗学的协议的高风险的病人。 | Alexander Darom Ilias P Gomatos Emmanuel Leandros Emmu Chatzigianni Dimitris Panousopoulos Manousos M Konstadoulakis George Androulakis | 2006 | World Journal of Gastroenterology2006，12，12： | 4 |
| 3 | Topographic patterns of intestinal metaplasia and gastric cancer显示文摘 | Mauro Cassaro Massimo Rugge Oscar Gutierrez Gioacchino Leandro David Y Graham Robert M Genta | 2000 | The American Journal of Gastroenterology2000，，： | 2 |
| 4 | Transfer of catechins and proanthocyanidins from solid parts of the grape cluster into wine显示文摘 | Pinto T Leandro M C | 1999 | Am J enol Vitic1999，50，： | 1 |
| 5 | Adsorption studies of methylene blue and gentian violet on sugarcane bagasse modified with EDTA dianhydride ( EDTAD ) in aqueous solutions : Kinetic and equilibrium aspects 显示文摘 | Km'la A G G Leandro V A G Tania M S M | 2013 | Journal of Environmental Management2013，118，： | 1 |
| 6 | Antioxidant and antimicrobial effects of phenolic compounds extracts of Northeast Portugal honey 显示文摘 | LETICIA E ANA P P LEANDRO M | 2008 | Food and Chemical Toxicology2008，46，： | 1 |
| 7 | The expression in Saccharomyces cerevisiae of a glucose/xylose symporter from Candida intermedia is affected by the presence of a glucose/ xyose facilitor 显示文摘 | Leandro M J Spencer-Martins I Goncalves P | 2008 | Microbiology2008，154，： | 1 |
| 8 | Reliability worth applied to transmission expansion planning based on ant colony system 显示文摘 | ARMANDO M LEANDRO S LUIZ A | 2010 | Electrical Power and Energy Sys- tems2010，32，10： | 1 |
| 9 | Hexose and pentose transport in ascomycetous yeasts:an overview显示文摘 | Leandro M J Fonseca C Goncalves P | | 0，，04： | 1 |
| 10 | Effects of Bacillus subtilis in the Dynamics of Infiltration of Immunological Cells in the Intestinal Mucosa of Chickens Challenged with Salmonella Minnesota显示文摘 | Camargo L M Leandro K N Patrick W | 2012 | Int J Poult Sci2012，11，5： | 1 |
| 11 | Clinical features of refluxesophagitis in older people:a study of 840 consecutive patients显示文摘 | Pilotto A Franceschi M Leandro G | 2006 | JAm Geriatr Soc2006，54，3： | 1 |
| 12 | Land-use and land- cover change in Alantic Forest landscapes显示文摘 | Paula K L Leandro R T Robert M E | 2012 | Forest Ecology and Management2012，278，： | 1 |
| 13 | B cell depletion thera- py in systemic lupus erythematosus: long-term follow-up and predictors of response显示文摘 | Ng K P Cambridge G Leandro M J | 2007 | Ann Rheum Dis2007，66，9： | 1 |
| 14 | Retinal vessel segmentation using the 2-D Gabor wavelet and supervised classification显示文摘 | Soares J V B Leandro J J G Cesar R M | 2006 | IEEE Transactions on Medical Imaging2006，25，9： | 1 |
| 15 | Preparation of hierarchically structured porous alumi- nas by a dual soft template method 显示文摘 | Leandro M | 2010 | Mieroporous and Meso- porous Materials2010，，132： | 1 |
| 16 | B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients 显示文摘 | LEANDRO M J CAMBRIDGE G EDWARDS J C | 2005 | Rheumatology2005，44，12： | 1 |
| 17 | Use of chaotic sequences in a biologically inspired algorithm for engineering design optimization显示文摘 | VIVIANA C M | 2008 | Expert Systems with Applications2008，34，3： | 1 |
| 18 | Hepatic stellate cell immunodetection and cirrhotic evolution of viral hepatitis in liver allografts显示文摘 | Guido M Rugge M Leandro G | 1997 | Hepatology1997，26，： | 1 |
| 19 | Life satisfaction of twoyear post-stroke survivors:effects of socioeconomic factors,motor impairment,Newcastle Stroke-Specific Quality of Life Measure and World Health Organization Quality of Life-bref of informal caregivers in Luxembourg and a rural area in portugal显示文摘 | Baumann M Lurbe K Leandro ME | 2012 | Cerebrovasc Dis2012，33，： | 1 |
| 20 | B cell depletion therapy in systemic lupus erythematosus: long-term follow-up and predictors of response显示文摘 | NG K P CAMBRIDGE G LEANDRO M J | 2007 | Ann Rheum Dis2007，66，9： | 1 |
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