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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | 中年成人平均动脉压的体位改变与动脉硬度的关系:Framingham心脏研究显示文摘Torjesen A, Cooper LL, Rong J, Larson MG, Hamburg NM, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Relations of arterial stiffness with postural change in mean arterial pressure in middle-aged adults:the Framingham heart study. Hyperten- sion,2017,69(4) :685-690.站立位血压稳定调节受损可导致不良结果,包括跌倒、晕厥和定向障碍。平均动脉压(meanarterialpressure,MAP)通常在站立位时增加,然而,站立位MAP增加不足或减少可能导致脑灌注减少。已有研究报道,在动脉硬度增加的老年人中存在体位性低血压,年轻至中年人MAP的体位性改变与动脉硬度的相关性尚未阐明。该研究分析了Framingham心脏研究第3代队列中的受试者3205人(女性1693人,占53%)的直立性血压反应和全面血液动力学数据。 | Torjesen A Cooper LL Rong J Larson MG Hamburg NM Levy D Benjamin EJ Vasan RS Mitchell GF 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，3： | 5 |
| 3 | Photocatalytic oxidation of ethanol:isotopic labeling and transient reaction显示文摘 | Mugli D S Larson S A Falconer J L | 1996 | J Phys Chem1996，100，15： | 3 |
| 4 | Evidence for a 15; 17translocation in every patient with acute promyelmytic leukemia显示文摘 | LARSON R A KONDO K VARDIMAN J W BUTLER A E GOLOMB H M ROWLEY J D | 1984 | Am J Med1984，76，5： | 1 |
| 5 | Diurnal variation of radon and mixing heights along a coast: a case study 显示文摘 | Hsu S A Larson R E Bressan D J | 1980 | Journal of Geophysical Research1980，85，： | 1 |
| 6 | Rapid com- munication: restriction fragment length polymorphisms at the porcine transporter associated with antigen processing 1 (TAP1) locus显示文摘 | Vaske D A Ruohonen M K Larson R ~ | 1994 | JAnim Sci1994，72，1： | 1 |
| 7 | The effect of setup uncertainties on the radiobiological advantage of fractionation in stereotaxic radiotherapy显示文摘 | Lo Y C Ling C C Larson D A | 1996 | In J Radiat Oncol Biol Plays1996，34，5： | 1 |
| 8 | Direct removal in the mouse of a floxed neo gene from a three-loxp conditional knockout allele by two novel approaches 显示文摘 | Li C Garrett-Beal L Larson D Wynshaw-Boris A Deng CX | 2001 | Genesis2001，30，1： | 1 |
| 9 | Local Derivations and Automorphisms of B(X)显示文摘 | Larson D R Sourour A R | | 0，，： | 1 |
| 10 | Traumatic intracranial aneurysms显示文摘 | Larson P S Reisner A Morassutti D J | | 0，，01： | 1 |
| 11 | The natural history of borderline isolated systolic hypertension显示文摘 | SAGIE A LARSON M G LEVY D | 1993 | N Engl J Med1993，329，： | 1 |
| 12 | The generation, of oceanic rhyolites by crustal fractionation: The basalt-rhyolite association at Volcano Alcedo, Galapagos Archipelago显示文摘 | Geist D Howard K A Larson P | 1995 | Journal of Petrology1995，36，： | 1 |
| 13 | Property rights,externalities,and resource degradation:Locating the tragedy显示文摘 | Larson B A Bromley D W | 1990 | Journal of Development Economics1990，33，2： | 1 |
| 14 | Technology Mediated Dispute Resolution (TMDR) : A New Paradigm for ADR显示文摘 | LARSON D A | 2006 | Ohio State Journal on Dispute Resolution2006，21，3： | 1 |
| 15 | The economics of air pollution health risks in Russia: a case study of Volgograd 显示文摘 | Larson B A Avaliani S Golub A Rosen S Shaposhnikov D Strukova E Vincent J R Wolff S K | 1999 | World development1999，27，10： | 1 |
| 16 | Is gratitude a moral affect 显示文摘 | McCullough M E Kilpatrick S D Emmons R A larson D B | 2001 | Psychological Bulletin2001，127，24： | 1 |
| 17 | Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans显示文摘 | Rhee Eugene P Cheng Susan Larson Martin G Walford Geoffrey A Lewis Gregory D McCabe Elizabeth Yang Elaine Farrell Laurie Fox Caroline S O’Donnell Christopher J Carr Steven A Vasan Ramachandran S Florez Jose C Clish Clary B Wang Thomas J Ger | 2011 | Journal of Clinical Investigation2011，，4： | 1 |
| 18 | Crystal size distribution in continuous crystallizer when growth rate is size-dependent 显示文摘 | Abegg C F Stevens J D Larson M A | 1968 | AIChE J1968，14，： | 1 |
| 19 | Therapist burnout: Perspectives on a critical issue 显示文摘 | Larson C C Gilbertson D L Powell J A | 1978 | Social Casework1978，，59： | 1 |
| 20 | Photocatalytic oxidation of ethanol: isotopic labelling and transient reaction 显示文摘 | Muggli D S Larson S A Falconer J L | 1996 | J Phys Chem1996，100，15： | 1 |
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