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| 1 | Collaboration for success:the value of strategic collaborations for precision medicine and biomarker discovery显示文摘Precision medicine aims to provide the precise treatment for the patient with the right dose at the right point of time.Biomarkers(BM)are vital for the identification of patients who would benefit the most from individualized treatment.In addition,they help to enable the prediction of prognosis,the detection of early therapeutic and adverse effects,and may serve as surrogate endpoints in clinical trials.BM are becoming essential tools to increase productivity in drug discovery and impressively enhance the way medicine is practiced.However,the identification,sufficient validation and implementation of such BM are challenging.This process requires expertise from different areas and high resource investments.Collaborations of different partners may be helpful to overcome these challenges.In the past decade,collaborations between diagnostics and pharmaceutical companies as well as industrial–academic collaborations have been increasingly pursued.Moreover,public funding may offer support and open new opportunities to form such consortia.Herein we give an overview of the different types of collaborations,their opportunities and challenges,and describe experiences in forming strategic partnerships with other companies. | Lilla Landeck Monika Lessl Joachim Reischl Andreas Busch Patricia Carrigan Matthias Gottwald Petra Reinke Khusru Asadullah | 2016 | Advances in Precision Medicine2016，1，1： | 3 |
| 2 | Solar observations from the P78-1 satellite显示文摘 | MCKENZIE D L LANDECKER P B | 1982 | Astrophys J1982，254，： | 1 |
| 3 | Types of integration and their measurement 显示文摘 | Landecker | 1951 | American Journal of Sociology1951，，4： | 1 |
| 4 | Dissolved oxygen control of the activated sludge wastewater treatment process using stable adaptive fuzzy control显示文摘 | Belchior C A C Araujo R A M Landeck J A C | 2012 | Computers & Chemical Engineering2012，37，： | 1 |
| 5 | Prevention and management of rhi- noplasty complications 显示文摘 | Cochran CS Landecker A | 2008 | Plast Reconstr Surg2008，122，2： | 1 |
| 6 | Harvesting rib cartilage grafts for secondary rhinoplasty显示文摘 | Matin VP Landecker A Gunter JP | 2008 | Plast Reconstr Surg2008，121，4： | 1 |
| 7 | Effect of sodium amylosulfate on the healing of duodenal ulcer显示文摘 | Landecker KD McCallum EM Fevre DI | 1976 | Gas-troenterology1976，71，5： | 1 |
| 8 | Assessment of long-term nipple projection:a comparison of three techniques显示文摘 | SHESTAK K C GABRIEL A LANDECKER A | 2002 | Plast Reconstr Surg2002，110，78： | 1 |
| 9 | Hippocampal Lewy pathol- ogy and cholinergic dysfunction are associated with dementia in Parkinson's disease显示文摘 | Hall H Reyes S Landeck N | 2014 | Brain2014，137，9： | 1 |
| 10 | The application of mesh support in periareolar breast surgery:clinical and mammographic evaluation显示文摘 | GOES J C LANDECKER A LYRA E C | 2004 | Aesthetic Plast Surg2004，28，5： | 1 |
| 11 | A new resorbable tack fixation technique for endoscopic brow lifts显示文摘 | Landecker A Buck JB Grotting JC | | 0，，2： | 1 |
| 12 | Types of Integration and Their Measurement显示文摘 | LANDECKER W S | | 0，，04： | 1 |
| 13 | Frequently used grafts in rhinoplasty: nomenclature and analysis 显示文摘 | Gunter JP Landecker A Cochran CS | 2006 | Plast Reconstr Surg2006，118，1： | 1 |
| 14 | Dissolved oxygen control of the activated sludge wastewater treatment process using stable adaptive fuzzy control 显示文摘 | BELCHIOR C A C ARAUJO R A M LANDECK J A C | 2012 | Computers & Chemical Engi- neering2012，37，2： | 1 |
| 15 | Absolute calibration of solar radio flux density in the microwave region显示文摘 | H. Tanaka J. P. Castelli A. E. Covington A. Krüger T. L. Landecker A. Tlamicha | 1973 | Solar Physics1973，，1： | 1 |
| 16 | Absolute calibration of solar radio flux density in the microwave region显示文摘 | H. Tanaka J. P. Castelli A. E. Covington A. Krüger T. L. Landecker A. Tlamicha | 1973 | Solar Physics1973，，1： | 1 |
| 17 | Frequently used grafts in rhinoplasty: nomenclature and analysis 显示文摘 | GUNTER J P LANDECKER A COCHRAN C S | 2006 | Plast Reconstr Surg2006，118，1： | 1 |
| 18 | Types of Integration and Their Measurement显示文摘 | Landecker W S | 1951 | The American Journal of Sociology1951，56，4： | 1 |
| 19 | Types of Integration and Their Measurement显示文摘 | Landecker W S | 1951 | The American Journal of Sociology1951，56，4： | 1 |
| 20 | Advances in precision medicine—time for a new journal显示文摘On January 20,2015,President Barack Obama announced a major research initiative,“Tonight,I am launching a new personalized medicine initiative to bring us closer to curing diseases like cancer and diabetes and to give all of us access to the personalized information we need to keep ourselves and our families healthier”.[1]The announcement itself indicates commitment and high expectations.Indeed personalized or precision medicine(PM)is presently considered to represent one of the most important trends in medicine.It may be regarded as another milestone in the‘evolution’of medicine beginning from the theory of ancient humoralism.This dominated medicine and science over a period or several thousands of years until the mid-nineteenth century when it was replaced by the introduction of modern cellular pathology.Further essential milestones on the way to PM are the discovery of the DNA by Watson and Crick in 1953 and the Human Genome Project determining to sequence the DNA that was completed in 2003[2]. | Lilla Landeck Robert L Holland Khusru Asadullah | 2016 | Advances in Precision Medicine2016，1，1： | 1 |
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