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| 1 | A cross-sectional study on compliance with topical glaucoma medication and its associated socioeconomic burden for a Chinese population显示文摘AIM: To estimate the overall drug compliance for local Chinese glaucoma patients on long-term topical treatment.METHODS: This was a retrospective cross-sectional study.Fifty-seven primary glaucoma patients from the subspecialty clinic of a publicly-funded tertiary care hospital in Hong Kong completed a questionnaire on compliance with topical glaucoma medication,attitude towards glaucoma and therapy and vision related quality of life.Noncompliance was defined as reporting missing more than or equal to 10% of the prescribed topical glaucoma medication during the 2wk immediately prior to the consultation.Relationships between noncompliance and demographics,attitude,disease and treatment status was studied.Cost was estimated with quality of life and direct medical cost involved with noncompliance.Multivariable logistic regression on noncompliance was performed on selected factors.RESULTS: Compliance was calculated as 75%(95% CI: 64%-87%) among 57 subjects(mean age 69 y,female 51%).No statistical significant relationship was established between noncompliance and any single factors or outcomes.Age(P=0.048) and forgetfulness(P=0.064) were found to be marginally significant predictive factors on noncompliance in multivariable logistic regression.Noncompliance might be related(P=0.130) to poorer self-rated vision-associated quality of life.The societal cost of noncompliance was estimated to be over 2510 life-years and US$ 3.7 million territory-wide.CONCLUSION: The compliance of Chinese glaucoma patients in Hong Kong is comparable to other parts in the world,and carries detrimental impacts on individual and societal levels.Age and forgetfulness are two possible independent predictors for noncompliance. | Man-Hin Lui Jason Chun Ho Lam Yi Lee Kwong Tak Siu Wong Pak Long Cheung Sherri Shun Yan Lai Pak Lun Yuen Wai Yiu Lam Ho Yan Chan Yiu Fai Wong Jimmy Shiu Ming Lai Kendrick Co Shih | 2017 | International Journal of Ophthalmology(English edition)2017，10，2： | 5 |
| 2 | Current phase lead compens- ation in single-phase PFC boost converters with a reduced switching frequency to line frequency ratio显示文摘 | Louganski K P Lai Jason | 2007 | IEEE Transactions on Power Electronics2007，22，1： | 1 |
| 3 | High- efficiency MOSFET inverter with H6-type configuration for photovoltaic nonisolated AC -module applications 显示文摘 | YU Wen-song Jih-Sheng (Jason) Lai | 2011 | IEEE Transactions on Power Electronics2011，26，4： | 1 |
| 4 | A high-efficiency grid-tie battery energy storage system 显示文摘 | Qian Hao Zhang Jianhui Lai Jih-Sheng (Jason) | 2011 | IEEE Transactions on Power Electronics2011，3，26： | 1 |
| 5 | Design of parallel inverters for smooth mode transfer microgrid applications显示文摘 | Chien-Liang Chen Yubin Wang Jih-Sheng (Jason) Lai | 2010 | IEEE Transactions on Power Electronics2010，25，1： | 1 |
| 6 | On the Performance of Wide-Area Thin-Client Computing显示文摘 | Albert M Lai Jason Nieh | 2006 | ACM Transactions on Computer Systems2006，24，2： | 1 |
| 7 | The Middle Permian (Capitanian) mass extinction on land and in the oceans显示文摘 | David P.G. Bond Jason Hilton Paul B. Wignall Jason R. Ali Liadan G. Stevens Yadong Sun Xulong Lai | 2010 | Earth Science Reviews2010，，1： | 1 |
| 8 | High-efficiency Grid-connected Photovoltaic Module Integrated Converter System With High-speed Communication Interfaces for Small-scale Dis- tribution Power Generation显示文摘 | Woo-Young Choi Jason Lai | 2010 | Solar Energy2010，84，4： | 1 |
| 9 | The role of the methyl ester moiety in biodiesel combustion:A kinetic modeling comparison of methyl butanoate and n-butane显示文摘 | Lin Kuang C Lai Jason Y W Violi Angela | | 0，，01： | 1 |
| 10 | 冰酒——凛冬专属佳酿显示文摘如果你对冰酒稍有了解,就会知道它产量极低,是世界上最昂贵的葡萄酒之一。一直以来,加拿大和德国是世界上最大的两个冰酒生产国。但自进入21世纪以来,辽宁省北部借助其得天独厚的天然环境,渐渐形成了完整的冰酒产业链,让世界刮目相看。你愿意在这个寒冬到那里去一探究竟吗? | Jason Lai BillyBudd | 2018 | 疯狂英语(新悦读)2018，0，1： | 0 |
| 11 | Impact of androgen-deprivation therapy on the outcome of dose-escalation prostate cancer radiotherapy without elective pelvic irradiation显示文摘在有为局部性的前列腺癌症的增强剂量的放射疗法(DERT ) 的联合的雄激素剥夺治疗(ADT ) 的利益没在使随机化的研究被决定。在这研究, ADT 的利益在一致地与增强剂量的调制紧张的放射治疗(IMRT ) 对待到前列腺和精囊然而并非骨盆的病人被估计。总共,有局部性的前列腺腺癌的 419 个病人经历了权威的 IMRT (累积剂量 78 Gy ) 与通过 T4 疾病的 32.6% , 33.1% , 32.1% ,和 2.1% 有的 T1,分别地,并且 51.2% 有高风险的疾病。ADT 被给 76.1% 病人。与 60 个月的中部的后续, 5 年的生物化学的没有失败、没有疾病、全面的幸存率分别地是 87% , 86% ,和 87% 。T 舞台是所有三率的一个独立预言者。五年的骨盆的节的复发率是 2.9% 。ADT 改进了生物化学的没有失败、没有疾病的幸存然而并非全面幸存。ADT 在高风险的疾病然而并非中间风险的疾病显示出利益。晚胃肠、泌尿生殖器的毒性等级 2 分别地发生在 11.0% 和 6.7% 。在结论,有 78 Gy 的 DERT 产出好疾病控制和骨盆的节的复发的低率。ADT 与高风险然而并非中间风险的疾病在病人改进没有疾病的幸存。 | Wei-Hsien Hou Chao-Yuan Huang Chia-Chun Wang Keng-Hsueh Lan Chung-Hsin Chen Hong-Jen Yu Shih-Ping Liu Ming-Kuen Lai Yeong-Shau Pu Jason Chia-Hsien Cheng | 2017 | Asian Journal of Andrology2017，19，5： | 0 |
| 12 | 乡愁中的古典与前卫——蓝舍艺术空间显示文摘在全球化与本土化的二元背景下解读岭南文化地方性与全球化常有博弈,古典与前卫也非属矛盾,传承与创新更可相互成全。从全球化和在地性的二元互动下,作为背靠中华大地,面向亚洲和世界的建筑师群体,我们关注更多的是在国际化和区域文化多样性的维度下展开建筑与文化身份认同的讨论。 | 无 丁劭恒 Jason Wei Amelia Chan Cowen Chow K.S.Kang Carrie Lai Kelvin Tam Young Chow Hobo Bryant Tim Kwok Liky Lin(摄影) | 2023 | 世界建筑导报2023，38，6： | 0 |
| 13 | Are EPB41 and alpha-synuclein diagnostic biomarkers of sport-related concussion?Findings from the NCAA and Department of Defense CARE Consortium显示文摘Background:Current protein biomarkers are only moderately predictive at identifying individuals with mild traumatic brain injury or concussion.Therefore,more accurate diagnostic markers are needed for sport-related concussion.Methods:This was a multicenter,prospective,case-control study of athletes who provided blood samples and were diagnosed with a concussion or were a matched non-concussed control within the National Collegiate Athletic Association-Department of Defense Concussion Assessment,Research,and Education Consortium conducted between 2015 and 2019.The blood was collected within 48 h of injury to identify protein abnormalities at the acute and subacute timepoints.Athletes with concussion were divided into 6 h post-injury(0-6 h post-injury)and after 6 h postinjury(7-48 h post-injury)groups.We applied a highly multiplexed proteomic technique that used a DNA aptamers assay to target 1305proteins in plasma samples from athletes with and without sport-related concussion.Results:A total of 140 athletes with concussion(79.3%males;aged 18.71±1.10 years,mean±SD)and 21 non-concussed athletes(76.2%males;19.14±1.10 years)were included in this study.We identified 338 plasma proteins that significantly differed in abundance(319 upregulated and 19 downregulated)in concussed athletes compared to non-concussed athletes.The top 20 most differentially abundant proteins discriminated concussed athletes from non-concussed athletes with an area under the curve(AUC)of 0.954(95%confidence interval:0.922-0.986).Specifically,after 6 h of injury,the individual AUC of plasma erythrocyte membrane protein band 4.1(EPB41)and alpha-synuclein(SNCA)were 0.956 and 0.875,respectively.The combination of EPB41 and SNCA provided the best AUC(1.000),which suggests this combination of candidate plasma biomarkers is the best for diagnosing concussion in athletes after 6 h of injury.Conclusion:Our data suggest that proteomic profiling may provide novel diagnostic protein markers and that a combination of EPB41 and SNCA is the most predictive biomarker of concussion after 6 h of injury. | Rany Vorn Christina Devoto Timothy B.Meier Chen Lai Sijung Yun Steven P.Broglio Sara Mithani Thomas W.McAllister Christopher C.Giza Hyung-Suk Kim Daniel Huber Jaroslaw Harezlak Kenneth L.Cameron Gerald McGinty Jonathan Jackson Kevin M.Guskiewicz Jason P.Mihalik Alison Brooks Stefan Duma Steven Rowson Lindsay D.Nelson Paul Pasquina Michael A.McCrea Jessica M.Gill the CARE Consortium Investigators | 2023 | Journal of Sport and Health Science2023，12，3： | 0 |
| 14 | Rails常见性能问题一览显示文摘作者从性能问题的角度,针对在分析Rails应用程序时遇到的影响各种应用程序性能的问题进行了详细分析,并针对读者感兴趣的问题给出忠告和编码技巧。 | Stefan Kaes Jason Lai(译) | 2007 | 程序员2007，，1： | 0 |
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