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| 1 | AMP-activated protein kinase inhibits transforming growth factor-beta-induced Smad3-dependent transcription and myofibroblast transdifferentiation 显示文摘 | Mishra R Cool BL Laderoute KR | 2008 | J Biol Chem2008，283，10： | 1 |
| 2 | The identi- fication of heme oxygenase as a major hypoxie stress protein in chinese hamster ovary ceils 显示文摘 | Murphy B J Laderoute K R Short S M | 1991 | Br J Cancer1991，64，1： | 1 |
| 3 | The Rational Design of a Novel Potent Analogue of the 5'-AMP-Activated Protein Kinase Inhibitor Compound C with Improved Selectivity and Cellular Activity显示文摘 | Maehrouhi F Ouhamou N Laderoute K | 2010 | Bioorg Med Chem Lett2010，20，： | 1 |
| 4 | Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/AKt signaling pathway in Haras-transformed ceils through a hypoxia inducible factor-1 transcriptional element显示文摘 | Mazure M Chen Y Laderoute R | 1997 | Blood1997，90，： | 1 |
| 5 | Hypoxia signals autophagy in tumor cells via AMPK activity,independent of HIF-1,BNIP3,and BNIP3L显示文摘 | Papandreou I Lim AL Laderoute K | 2008 | Cell Death Differ2008，15，： | 1 |
| 6 | SUll248 (sunitinib) directly inhibits the activity of mammalian 5'-AMP-acti- vated protein kinase (AMPK) 显示文摘 | Laderoute K R Calaoagan J M Madrid P B | 2010 | Cancer Biology & Therapy2010，，： | 1 |
| 7 | Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1显示文摘 | Murphy B J Andrews G K Bittel D Discher D J McCue J Green C J Yanovsky M Giaccia A Sutherland R M Laderoute K R Webster K A | | 0，，06： | 1 |
| 8 | Glucose utilization is essential for hypoxia-inducible factor 1-dependent phosphorylation of c-Jun显示文摘 | Laderoute KR Calaoagan JM Knapp M | 2004 | Mol Cell Biol2004，24，： | 1 |
| 9 | Inhibition of human bladder cancer cell motility by genistein is dependent on epidermal growth factor receptor but not p21ras gene expression 显示文摘 | Theodorescu D Laderoute KR Calaoagan JM | 1998 | Int J Cancer1998，78，6： | 1 |
| 10 | The interaction between HIF-1 and AP-1 transcription factors in response to low oxygen显示文摘 | Laderoute K R | 2005 | Semin Cell Dev Biol2005，16，45： | 1 |
| 11 | Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element显示文摘 | Mazure NM Chen EY Laderoute KR | 1997 | Blood1997，90，9： | 1 |
| 12 | Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor显示文摘 | LADEROUTE K ALARCON R BRODY | 2000 | Clin Cancer Res2000，，6： | 1 |
| 13 | Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/AKT signaling in HA-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element显示文摘 | Mazure NM Chen EY Laderoute KR | 1997 | Blood1997，90，： | 1 |
| 14 | 5'-AMP-activated protein kinase(AMPK)is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments显示文摘 | Laderoute KR Amin K Calaoagan JM | | 0，，14： | 1 |
| 15 | Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L 显示文摘 | PapandreouI Lim AL Laderoute K | 2008 | Cell Death Differ2008，15，10： | 1 |
| 16 | Hypoxia reoxygeneration stimulates jun Kinase activity through redox signaling in cardiac myocyes circ显示文摘 | Laderoute KP Webster KA | 1997 | Res1997，80，： | 1 |
| 17 | Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element 显示文摘 | Mazure NM Chen EY Laderoute KR | 1997 | Blood1997，90，： | 1 |
| 18 | 5'-AMP-activated Protein Kinase (AMPK) Supports the Growth of Aggressive Experi- mental Human Breast Cancer Tumors显示文摘 | Laderoute KR Calaoagan JM chao WR eta/ | 2014 | J Bid Chem2014，289，22： | 1 |
| 19 | Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF - 1, BNIP3, and BNIP3L显示文摘 | Papandreou I Lim AL Laderoute K | 2008 | Cell Death Differ2008，15，： | 1 |
| 20 | Hypoxia signals autophagy in tumor cells via AMPK activity, indepen- dent of HIF-1, BNIP3, and BNIP3L显示文摘 | PAPANDREOU I LIM A L LADEROUTE K et ol | 2008 | Cell Death and Differ- entiation2008，15，10： | 1 |
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